Infectious Disease Block

A 47 year old man who presents in the ED with symptoms of fever, nausea, neck stiffness and severe headache is diagnosed with bacterial meningitis caused by Haemophilus influenzae. Which of the following is a beta-lactam antibiotic that could adequately cross the blood brain barrier and be used to treat this type of infection?
Chloramphenicol
Ceftriaxone (3rd Gen cephalosporin)
Cephalexin (1st Gen cephalosporin)
Clofazimine
Tazobactam
A 34 year old HIV-positive man with a persistent cough and chest pain has a positive response to a Mantoux tuberculin skin test. Blood tests confirm the presense of TB infection, and the patient is started on combination drug therapy. A few months later the patient develops a bilateral numbness and tingling of his upper and lower extremities, attributed to drug-induced peripheral neuropathy. Which agent is most likely responsible?
Clindamycin
Ethambutol
Isoniazid
Pyrazinamide
Rifampin
A 24 year old African American woman with a history of anaphylaxis to amoxicillin is treated with an oral antibiotic for cystitis (urinary tract infection). A few days later she develops a fever, weakness, dark-colered urine, and a yellow discoloration of her eyes. Lab tests confirm that she is suffering from hemolytic anemia, and that she also has a mild deficiency in glucose-6-phosphate dehydrogenase (a genetic condition that was previously undiagnosed). The most likely cause for her anemia is:
Ceftriaxone (3rd Gen cephalosporin)
Imipenem (a carbapenem)
Nitrofurantoin
Piperacillin + Tazobactam
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