8.6 Medicamente cu actiune asupra micobacteriilor
Test Your Knowledge on Antitubercular Drugs
Welcome to the quiz designed for healthcare professionals and students! This quiz focuses on key medications that affect mycobacteria, particularly in the treatment of tuberculosis.
Test your understanding of:
- Common antitubercular drugs
- Pharmacokinetics of isoniazid
- Adverse reactions associated with these medications
- Treatment regimens for Mycobacterium tuberculosis
Sunt medicamente utilizate in tratamentul tuberculozei
Acid acetilsalicilic
Etambutol
Rifampicina
Rezerpina
Izoniazida
Izoniazida din punct de vedre farmacocinetic:
Este slab absorbita la administrarea per os
Nu traverseaza bariera hemato-encefalica
Este metabolizata la compusi inactivi
Este eliminata exclusiv prin saliva, transpiratie, lapte, fecale,
Este eliminata dupa N-acetilare.
Reactiile adverse care se pot produce la administrarea izoniazidei sunt:
Nevrita periferica
Nefrita
Hematurie
Unele reactii de hipersensibilitate
Hepatita
Hidrazida acidului nicotinic,cel mai eficient medicament antituberculos, este:
Bacteriostatic pentru bacilii aflati in faza de multiplicare rapida
Bacteriostatic pentru bacilii aflati in faza stationara
Bactericid pentru bacilii aflati in starea de multiplicare rapida
Bactericid pentru bacilii aflati in faza stationara
Fungicid
Schema de tratament in infectiile cu Mycobacterium tuberculosis include:
Izoniazida(monoterapie)
Izoniazida, rifampicina, etambutol, streptomicina(medicamente de electie administrate cate doua sau trei)
Tratament de scurta durata
Tratament cu durata de la cateva zile pana la doi ani
Mai multe medicamente ca urmare a rezistentei crescute(polichimiorezistenta) a tulpinilor de microorganisme.
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