RNA

A zinc finger is a structural motif that participates in:

Replication

Translation

Transcription

Protein synthesis

In the absence of glucose and lactose, which of the following occurs in transcription?

Increased cAMP levels result in binding to the catabolite activator protein

Increased allolactose levels bind to the repressor

Decreased cAMP levels result in poor binding to the catabolite activator protein

Repressor releases from lac operator

Which of the following tRNA sites is the binding site for amino acids?

5' tail

Anticodon

Dihydrouracil arm

CCA tail

Alpha-amanitin mushroom toxin inhibits ____________________ causing __________________

RNA polymerase I, hepatotoxicity

RNA polymerase II, hepatotoxicity

RNA polymerase III, cancer

RNA polymerase II, pancreatitis

Modifications that hnRNA suffers to become mRNA

5' cap, poly A tail, splicing of introns

5' cap, poly A tail, splicing of exons

poly A tail, splicing of introns

5' cap, poly A tail

Antibodies to spliceosomal snRNPs (anti-smith) are specific for:

Rheumatoid arthritis

Systemic Lupus Erythematosus

Psoriasis

Mixed connective tissue disease

Contain the actual genetic information coding for protein

Introns

Spliceosomes

Exons

hnRNA

Site where the incoming Aminoacyl-tRNA is located

A site

P site

E site

Which of the following medications block the A site in the ribosome preventing binding of amynoacyl transferase

Linezolid

Tetracyclines

Aminoglycosides

Macrolides

Antibiotic that blocks translocation

Linezolid

Tetracyclines

Aminoglycosides

Macrolides

Intracellular protein involved in facilitating and/or maintaining protein folding

Spliceosome

Chaperone

amynoacyl tRNA

peptydyl transferase

Site of the ribosome that acommodates the growing peptide

A site

P site

E site

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