MPN Quiz #4

1. Which patient with essential thrombocythemia (ET) should be started on cytoreductive therapy?
63-year-old male with no thrombosis history and CALR mutation positive
37-year-old female with a history of a DVT
60-year-old male with no cardiovascular risk factors and JAK2 wild type
56-year-old female with hypertension and JAK2 mutation
All patients with ET should be started on low-dose aspirin. True or False?
True
False
Which molecular mutation in ET seems to be associated with higher risk of thrombosis?
MPL
CALR
JAK2
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