Biomaterials Tutorial
Biomaterials Quiz: Test Your Knowledge
Welcome to the Biomaterials Quiz! This engaging quiz consists of 48 questions designed to test your understanding of various aspects of biomaterials and their applications in medicine. Whether you are a student, teacher, or just someone interested in the field of biomaterials, this quiz offers a valuable opportunity to enhance your knowledge.
- Multiple choice questions
- Covers topics from chemistry to application in medicine
- Perfect for students and professionals alike
How is a biomaterial different than a regular material?
A biomaterial is made out of a special material
A biomaterial is only used inside the human body
A biomaterial serves a medical purpose and interacts with a biological system
There is no difference, as these are made from the same material types
Developing a biomaterial requires that (choose most critical one)
It is strong and durable
It is biocompatible
It solves a medical problem
It can be used by everybody
For many biomaterials degradability is essential and this can be done by
Slow dissolution of the material
Breaking chemical bonds that break-up the material into small soluble components
Using the immune cells to clear materials and degrade them
All of the above
Polylactic acid has an ester bond which is composed out of
An alcohol group and amine group
An alcohol group and carboxylic acid
An amine group and carboxylic acid
Is created by ring-opening reaction
When a condensation reaction occurs there is most likely formation of
Water
A small molecule
An ester
All of the above
Amides are found in
Collagen
Silicone
Polypropylene
All of the above
A hydrogel needs cross-links which are
Made by covalent bonds
Made by charges or hydrophobic interactions
Made by both covalent and non-covalent bonds
Made by long range interactions with water which hold the network together
Biomaterials are only relevant for in vivo medical applications
Yes, because biomaterials need to fulfill a medical problem which is only addressable with an implant
Yes, because it needs to interact with a biological system
No, because also sensing of biological samples outside the body can be considered a biomaterial
No, biomaterials are also used even outside the medical field
The formation of polylactic acid from lactic acid is a
Step-growth mechanism
Chain-growth mechanism
Radical formation
Ring-opening mechanism
For a chain-growth mechanism
An initiator is needed
A small molecule is formed
The radical polymerization is the only reaction that shows this mechanism
The number of polymer chains inside the reaction is reduced
Which of the following reactions is not a termination?
Disproportionation
Hydrolysis
Chain transfer
Recombination
Radical polymerization is compatible with many environmental conditions but
Not with oxygen
Not with protein
Not with cells
Not with water
Which polymer properties will directly influence the mechanical properties?
Molecular weight
Molecular weight distribution
Monomer composition within the polymer
All mentioned
Which of the following classes of polymers degrades the slowest?
Polyacrylates
Polyesters
Polyamides
Polypeptides
Which of the following classes of polyemers degrades the fastest?
Polyacrylates
Polyesters
Polyamides
Polypeptides
A contact lens made of Polymethylmethacrylate is
Hard
Soft
A hydrogel
An elastomer
For bulk erosion of a biodegradable implant, the implant will
Lose mass and volume
Lose mass but retain its volume
Lose mass only from the surface
Lose only volume
Responsive polymers have a general mechanism with different stimulus
All responsive polymers increase their interactions with themselves and therefore collapse
All responsive polymers locally increase in temperature in a response to the change in reactivity and therefore collapse
All responsive polymers lose their affinity to water which makes them collapse
All mentioned contribute jointly
A biomaterial is always a synthetic material
Yes, as it is always made by a person/machine
Yes, biomaterials are always composed of polymers or metals which are synthetic
Yes, because natural structures are always mimicked synthetically
No, a biomaterial can also be derived from natural products
Biomaterials are composed of
Polymers and metals
Polymers, metals, and ceramics
Small molecules, polymers, and metals
Small molecules, polymers, metals, and ceramics
Polymers are important within biomaterials because
They are applicable to many different systems due to their diverse nature in properties
They are the only class of materials that is easy to process
They are able to form hydrogels
They offer most possibilities to further improve them
Synthetic polymers have the potential to be responsive and they might respond to
PH, temperature, and light
PH, ions, and temperature
PH, temperature, light, and ions
None, because only a natural polymer has these properties
The responsiveness of polymers towards various stimulus has a single common mechanism, which is
A reversible change in charge
A reversible change in water coordination
A reversible cross-linking
Not true, as the mechanism depends on the type of response chosen
For which type of fixation would one use bone cement?
Morphological fixation
Biological fixation
Bioactive fixation
Reasorption
A porous material would be most likely fixed via
Morphological fixation
Biological fixation
Bioactive fixation
Reasorption
Hydroxyapatite would most likely connect to bone via
Morphological fixation
Biological fixation
Bioactive fixation
Reasorption
Hydroxyapatite is considered a
Ceramic
Composite
Metaoxide
Inorganic polymer
Stainless steel is a corrosion resistant material alloy in which much iron is porcessed but still there is no rust formation because
A special form of iron is used that is less susceptible for corrosion
The surface is implemented with nitrogen to make it more stable
The chromium iin stainless steel induces controlled oxidation
Stainless steel has iron in the form of 3+ ions which cannot oxidize further
Alloys are very powerful as it will introduce properties into a material that are otherwise not possible. Which material has superflexibility?
Nitinol
Titanium
Cobaltchrome
Aluminiumoxide
Biomaterials are used in the dimensions of
Nanometers
Micrometers
Centimeters
All of the above
A hydrogel is
A network of polymers
A networks that is able to contain a solvent
A network that is able to contain water
A porous system that is able to entrap water
A hydrogel is made of
Synthetic polymers
Natural polymers
Small molecules
All of the above
A hydrogel inspires biomaterial scientists because they
Are easy to make
Are applicable to various orthopedic implants
Resemble the natural extracellular matrix in which cells reside
Are soft
A hydrogel increases in stiffness when
There are more water molecules entrapped in the network
The temperature of the gel is at body temperature
There are more cross-links
There are many chemical functionalities present
Alginate is a common hydrogel that is being used in biomaterials because it
It is a natural polymer that is present also in humans
Is easily cross-linkable using multivalent anions
Responds to various stimuli such as temperautre, ions, light
Can be used as a two component system where multivalent salt solution is mixed with alginate
Alginate cross-links the strongest at equal concentration with
Ca(2+)
Fe(3+)
Fe(2+)
Na(+)
Hydrogels are made of many different polymers such as
Polyethylene, polytetrafluoroethylene
Polylactic acid, alignate
Polylactic acid, polyglycolic acid
All of these polymers
There are many materials that are used from natural origin of resemble natural components. Which one is NOT of natural origin?
Collagen
Gelatin
Polylactic acid
Hydroxyapatite
Titanium is often used as a medical implant but the surface of the implant is not titanium because
There is a protein layer on the surface
There is always another metal placed on the surface
It contains an oxide layer on the surface
A layer of water coordinates to the surface
Metals can only serve as macroscopic materials or implants
True, because on the nanoscale the properties change which is then not useful anymore
True, because the metals will be much more reactive because of the higher volume-to-surface ratio at the nanoscale
False, because metallic nanoparticle can be made and are useful for different application
False, because macroscopic materials are composed of nanoscopic metallic nanoparticle so they both exist simultaneously
Nanoparticles can be made via
Top-down process
Bottom-up process via self-assembly
Bottom-up process via chemical reaction
All of the above
Properties of nanoparticles may differ from the macroscopic materials. The color is one of these which is due to
Refraction of light
Change in electronic properties
Due to the water layer that is formed around it in solution
Properties do not change, the color is not affected when making nanomaterials
For the formation of a metallic nanoparticle such as gold you would need
Metal salt, reducing agent, stabilization agent, very high temperature
Metal salt, reducing agent, stabilization agent
Metal, oxidizing agent, low temperature
Metal, oxidizing agent, stabilization agent
To alter the interaction between material and environment, a coating can be applied. Which coating is integrated into the material?
Overcoat
Surface gradient
Chemical reaction
Polyelectrolyte multilayer
A hydroxyapatite coating on an orthopedic implant is applied as a
Overcoat
Surface gradient
Self-assembled monolayer
Polyelectrolyte multilayer
Nitriding is a coating best related to
Overcoat
Surface gradient
Self-assembled monolayer
Polyelectrolyte multilayer
For applying coating to nanomaterials, a completely different strategy needs to be applied than for macroscopic materials
True, because a nanomaterial is very different in chemistry than a macroscopic material
True, because the coating thickness of a macromaterial is thicker than the size of a nanomaterial and thus not compatible
False, because the properties such as chemistry are the same and the coating thickness easily controlled
False, because nanomaterials do not need a coating as they are too small to negatively influence biological systems
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