Question 59

You astutely suspect Primary CNS lymphoma in a 72 year old gentleman who presented with recurrent posterior uveitis. You do a vitreous biopsy to obtain some of the cellular infiltrate. The most likely cytologic description of the abnormal vitreous cells in a patient with Primary CNS lymphoma would be:
Plasma cells with atypical nucleoli
Tissue macrophages expressing CD45
Large lymphocytes with high nucleus to cytoplasm ratio
Mature T lymphocytes expressing CD8
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