4th Cardiovascular USMLE

 
301
As you are examining the patient described in the previous question, he starts to complain of chest discomfort and shortness of breath and has another syncopal episode. His ECG is shown below. Which of the following is the most appropriate next step in management?
Call cardiology consult
Cardiovert the patient
Administer metoprolol
Administer amiodarone
Apply transcutaneous pacemaker
A 19-year-old woman was attacked while coming home from a party and is brought to the emergency department. She recalls being punched in the side of the head and stabbed in the left flank. Her speech is slow and she complains of a bad headache. Her pulse is 110/min, blood pressure is 90/50 mm Hg, and respiratory rate is 25/min. On examination she has a stab wound at the left costal margin in the midaxillary line. Two large-bore intravenous lines are inserted, and after infusion of 2 L of lactated Ringer’s solution her blood pressure rises to 95/55 mm Hg. What is the most appropriate next step in management?
Abdominal ultrasound
Diagnostic peritoneal lavage
Exploratory laparotomy
Noncontrast CT of the head
Peritoneal laparoscopy
A 34-year-old woman presents to your office complaining of several months of chest pain. She says that the pain is left-sided, does not change with deep inspiration, and typically lasts several hours. The pain has no relation to physical activity, but worsens with emotional stress. The patient has no significant family history, and does not use tobacco, alcohol or drugs. She takes no medications and has no drug allergies. On exam, her blood pressure is 110/70 mmHg and her heart rate is 78/min. ECG is normal. Which of the following is the best next step in her management?
Reassurance
Stress ECG testing
Transthoracic echocardiography
Lower extremity venous ultrasonography
Chest X-ray
A 60-year-old male patient is receiving aspirin, an angiotensin-converting enzyme inhibitor, nitrates, and a beta-blocker for chronic stable angina. He presents to the ER with an episode of more severe and long-lasting angina chest pain each day over the past 3 days. His ECG and cardiac enzymes are normal. Which of the following is the best course of action?
Admit the patient and add intravenous digoxin.
Admit the patient and begin low-molecular-weight heparin.
Admit the patient for thrombolytic therapy.
Admit the patient for observation with no change in medication.
Increase the doses of current medications and follow closely as an outpatient.
While palpating the pulse of a patient, you note that the pulse wave has two peaks. You auscultate the heart and are certain that there is only one heartbeat for each two pulse waves. Which of the following best describes this finding?
Pulsus alternans
Dicrotic pulse
Pulsus parvus et tardus
Pulsus bigeminus
Pulsus bisferiens
A 42-year-old female with acute pericarditis develops jugular venous distention and hypotension. The ECG shows electrical alternans. Which of the following is the most likely additional physical finding?
Basilar rales halfway up both posterior lung fields
S3 gallop
Pulsus paradoxus
Strong apical beat
Epigastric tenderness
Yesterday you admitted a 55-year-old white male to the hospital for an episode of chest pain, and you are seeking to rule out MI plus assess for any underlying coronary artery disease. The patient tends to be anxious about his health. On admission, his lungs were clear, but his heart revealed a grade 1/6 early systolic murmur at the upper left sternal border without radiation. Blood pressure readings have consistently been in the 140/90 to 150/100 range. Cardiac enzymes are normal. A resting ECG shows only left ventricular hypertrophy with secondary ST-T changes (“LVH with strain”). Why would a treadmill ECG stress test not be an appropriate test in this patient?
Anticipated difficulty with the patient’s anxiety (ie, he might falsely claim chest pain during the test)
Increased risk associated with high blood pressure readings
Concern about the heart murmur, a relative contraindication to stress testing
The presence of LVH with ST-T changes on baseline ECG
Concern that this represents the onset of unstable angina with unacceptable risk of MI with stress testing
A 67-year-old male presents to your office after community ultrasound screening revealed an aortic aneurysm measuring 3.0 x 3.5 cm. Physical examination confirms a palpable, pulsatile, nontender abdominal mass just above the umbilicus. The patient’s medical conditions include hypertension, hyperlipidemia, and tobacco use. What is the best recommendation for the patient to consider?
Watchful waiting is the best course until the first onset of abdominal pain.
Surgery is indicated except for the excess operative risk represented by the patient’s risk factors.
Serial follow-up with ultrasound, CT, or MRI is indicated, with the major determinant for surgery being aneurysmal size greater than 5 to 6 cm.
Serial follow-up with ultrasound, CT, or MRI is indicated, with the major determinant for surgery being involvement of a renal artery.
Unlike stents in coronary artery disease, endovascular stent grafts have proven unsuccessful in the management of AAAs.
A 67-year-old male presents to your clinic to establish primary care; he is asymptomatic. He has a history of hypertension for which he takes hydrochlorothiazide. His father had a myocardial infarction at age 62. The patient smoked until 5 years ago, but has been abstinent from tobacco since then. His blood pressure in the office today is 132/78. Aside from being overweight, the remainder of the physical examination is unremarkable. Which of the following preventive health interventions would be most appropriately offered to him today?
Carotid ultrasound to evaluate for carotid artery stenosis
Abdominal ultrasound to evaluate for aortic aneurysm
Lipoprotein(a) assay to evaluate coronary heart disease risk
Exercise (treadmill) stress testing to evaluate for coronary artery disease
Homocysteine level to evaluate coronary heart disease risk
 
310
You are called by a surgical colleague to evaluate a 54-year-old woman with ECG abnormalities one day after a subtotal thyroidectomy for a toxic multinodular goiter. Her only medication is fentanyl for postoperative pain control. The patient denies any history of syncope, and has no family history of sudden cardiac death. Physical examination is unremarkable except for a clean postoperative incision at the base of the neck. Her ECG is reproduced below. What is the best next step in evaluation and management of this patient?
Administration of intravenous magnesium sulfate
Measurement of serum ionized calcium
Stat noncontrast CT scan of the brain
Formal auditory testing
Reassure the patient that her ECG is normal for a woman her age
A 36-year-old man presents to the clinic with complaints of a genital sore. The patient is a sexually active heterosexual involved with three partners and practices unprotected intercourse. Four days ago he noted a painless sore on his penis. He is afebrile, with a heart rate of 80/min and blood pressure of 120/77 mm Hg. Physical examination reveals a solitary ulcerated lesion located on the lateral aspect of his penis. The lesion is nontender and associated with bilateral inguinal lymphadenopathy. Physical examination is otherwise normal. If left untreated, this man is at increased risk for which of the following?
Ascending aortic aneurysm
Coronary artery aneurysm
Endocarditis
Mitral valve stenosis
Rupture of ventricular free wall
An 81-year-old man is hospitalized for acute onset of shortness of breath and lower extremity edema. Although he lives by himself, it is very difficult for him to move around his apartment without experiencing fatigue. He has not seen his physician in years but was told in the past that he had high blood pressure. On physical examination his jugular venous pulse is palpated 9 cm above his sternal notch, inspiratory crackles are heard at his lung bases, and there is 3+ lower extremity edema. Which of the following will confirm the most likely diagnosis?
Cardiac angiography
Echocardiography
Electrocardiogram
Endomyocardial biopsy
X-ray of the chest
A 42-year-old man presents to the clinic for routine evaluation. His medical history is signifiedcant for gallstones. The patient denies smoking and drinks alcohol occasionally. His mother had a heart attack at the age of 63 years. His blood pressure is 134/77 mm Hg. The patient is overweight with well-healed laparoscopic cholecystectomy scars. Fasting laboratory tests show: Aspartate aminotransferase: 37 U/L Alanine aminotransferase: 28 U/L Alkaline phosphatase: 88 U/L Total cholesterol: 268 mg/dL LDL cholesterol: 183 mg/dL HDL cholesterol: 46 mg/dL Triglycerides: 166 mg/dL What is the most appropriate next step in management?
A trial of lifestyle modification alone (diet, exercise, and weight loss)
A trial of lifestyle modification combined with statin and niacin therapy
A trial of lifestyle modification combined with statin therapy
Niacin therapy
Statin therapy
A 62-year-old man with a prosthetic aortic valve develops fevers and malaise. His valve was replaced 5 years ago because of aortic stenosis from a bicuspid valve. He has a systolic ejection murmur but no other abnormalities on examination. Blood cultures are most likely to grow which of the following?
Fungi
Bartonella
Diptheroids
Staphylococcus epidermidis
Streptococcus bovis
A 58-year-old man with no prior cardiac history presents with retrosternal chest pain starting at rest and lasting 30 minutes. The pain radiates to the left arm and is associated with diaphoresis and dyspnea. His blood pressure is 150/90 mm Hg, pulse 100/min, the heart sounds are normal, and the lungs are clear to auscultation. Which of the following is the next most appropriate investigation?
CT scan chest
CXR
Cardiac troponin
ECG
Myocardial perfusion imaging
 
316
The laboratory results shown in Table 1–1 are obtained from the investigation of a 37-year-old African-American woman who has a blood pressure at rest of 140/100 mm Hg. Which of the following is the most likely diagnosis?
Cushing’s syndrome
Primary aldosteronism
Essential hypertension
Pyelonephritis
Bilateral renal artery stenosis
 
317
Image below is the x-ray and MR of an 8-year-old boy who had easy fatigability and a soft, continuous murmur in the upper back. ECG revealed minimal LVH. What is your diagnosis?
Aortic stenosis
Patent ductus arteriosus
Coarctation of the aorta
Pulmonary valvular stenosis
Peripheral pulmonary stenosis
A 60-year-old man with a history of congestive heart failure presents to his physician. He has a 5-year history of excessive daytime sleepiness and snoring. He also admits to three drinks of alcohol per day. His temperature is 36.6°C (98.0°F), pulse is 85/min, blood pressure is 138/82 mm Hg, respiratory rate is 14/min, and oxygen saturation is 99% on room air. His body mass index is 31 kg/m2. Physical examination is significant for macroglossia and a short neck. Polysomnography is performed and is significant for multiple nocturnal episodes of airflow cessation at the nose and mouth, despite evidence of continuing respiratory effort. Which of the following is the most effective management for this patient?
Avoidance of alcohol
Avoidance of supine posture
Nasal continuous positive airway pressure
Uvulopalatopharyngoplasty
Weight reduction
During a screening physical examination for participating in high school sports, a 14-yearold girl is found to have a late apical systolic murmur preceded by a click. The rest of the examination is unremarkable. Echocardiography shows superior displacement of the mitral leaflets of >2 mm during systole into the left atrium, with a thickness of at least 8 mm. In addition, she states that her father also has some type of heart “murmur,” but she knows nothing else about it. Which of the following is the most appropriate management at this time?
Digoxin
Instruct the patient to avoid all forms of strenuous activity
Metoprolol
Mitral valve replacement
Prophylactic antibiotics for dental procedures
A 20-year-old woman arrives at the emergency department actively seizing with QRS prolongation on ECG per paramedics. The patient’s roommate called emergency medical services after the patient collapsed, was not responsive to questioning, and began having clonic jerks bilaterally in her upper extremities. The patient’s roommate denies any knowledge of the patient consuming alcohol or illicit drugs. She does not believe the patient had any plan of harming herself, but does acknowledge that the patient has seemed “down” lately and was recently prescribed medication for generalized anhedonia. Which of the following is the most appropriate first-line treatment?
Activated charcoal
Diazepam
Flumazenil
Physostigmine
Sodium bicarbonate and diazepam
 
331
78-year-old woman presents to a nursing home physician complaining of palpitations over the past several months. Her episodes are not associated with any chest pain, dizziness, or loss of consciousness. The patient reports that she spent several weeks in the hospital as a child with rheumatic fever. ECG is shown in the image. Which of the following is the most likely diagnosis?
Atrial fibrillation
Atrial flutter
Multifocal atrial tachycardia
Paroxysmal atrial tachycardia
Paroxysmal supraventricular tachycardia
A 67-year-old woman is brought to the ED by paramedics complaining of dyspnea, fatigue, and palpitations. Her BP is 80/50 mm Hg, HR is 139 beats per minute, and RR is 20 breaths per minute. Her skin is cool and she is diaphoretic. Her lung examination reveals bilateral crackles and she is beginning to have chest pain. Her ECG shows a narrow complex irregular rhythm with a rate in the 140s. Which of the following is the most appropriate immediate treatment for this patient?
Diltiazem
Metoprolol
Digoxin
Coumadin
Synchronized cardioversion
A 61-year-old woman with a history of congestive heart failure (CHF) is at a family picnic when she starts complaining of shortness of breath. Her daughter brings her to the ED where she is found to have an oxygen saturation of 85% on room air with rales halfway up both of her lung fields. Her BP is 185/90 mm Hg and pulse rate is 101 beats per minute. On examination, her jugular venous pressure (JVP) is 6 cm above the sternal angle. There is lower extremity pitting edema. Which of the following is the most appropriate first-line medication to lower cardiac preload?
Metoprolol
Morphine sulfate
Nitroprusside
Nitroglycerin
Oxygen
A 27-year-old man complains of chest palpitations and lightheadedness for the past hour. He has no past medical history and is not taking any medications. He drinks a beer occasionally on the weekend and does not smoke cigarettes. His HR is 180 beats per minute, BP is 110/65 mm Hg, and oxygen saturation is 99% on room air. An ECG reveals an HR of 180 beats per minute with a QRS complex of 90 milliseconds with a regular rhythm. There are no discernable P waves. Which of the following is the most appropriate medication to treat this dysrhythmia?
Digoxin
Lidocaine
Amiodarone
Adenosine
Bretylium
 
325
A 59-year-old man presents to the ED with left-sided chest pain and shortness of breath that began 1 hour ago. Initial vital signs are BP 85/45 mm Hg, HR 105 beats per minute, RR 20 breaths per minute, and oxygen saturation 94% on room air. An ECG is seen below. Which of the following is the most appropriate definitive treatment?
Administer metoprolol or diltiazem
Electrical cardioversion
Administer calcium gluconate
Thrombolytic therapy
Percutaneous angioplasty
A 28-year-old man with a history of intravenous drug abuse presents to the emergency department with a 2-day history of fever, chills, and shortness of breath. On physical examination the patient has a new heart murmur, small retinal hemorrhages, and subungual petechiae. Which of the following is the most likely causative organism?
Group A Streptococcus
Mycobacterium tuberculosis
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus viridans
A boy is delivered at 37 weeks’ gestation via spontaneous vaginal delivery. He is the product of a normal pregnancy and was delivered without complications. Prenatally the mother was blood type B and was rubella immune and negative for Rh antibody, group B streptococci, rapid plasma reagin, hepatitis B surface antigen, gonorrhea, and chlamydia. The patient appears cyanotic. He is breathing at a rate of 60/min and his heart rate is 130/min. He has a normal S1 and S2. There is a harsh holosystolic murmur that is loudest at the left lower sternal border. His examination reveals palpable nonbounding peripheral pulses bilaterally. Which of the following is the most likely diagnosis?
Coarctation of the aorta
Dextraposed transposition of the great arteries
Patent ductus arteriosus
Tetralogy of Fallot
Truncus arteriosus
A 32-year-old man is stabbed in the left chest and presents to the emergency department in distress. His pulse is 130/min, blood pressure is 70/50 mm Hg, and respiratory rate is 39/min. The stab wound is in the left fifth intercostal space in the midaxillary line. On examination his trachea is deviated to the right, jugular veins are distended bilaterally, and he has absent breath sounds and hyperresonance to percussion on the left side. Subcutaneous emphysema is palpated on the left thoracic wall. What is the best next step in management?
Chest tube thoracotomy
Diagnostic peritoneal lavage
Needle thoracostomy
Pericardiocentesis
Surgical exploration
A 75-year-old man comes into the emergency department with a 10-minute history of crushing substernal chest pain radiating to his left arm. This man is well known to the staff due to his long history of chest pain. His creatine phosphokinase level is elevated and his troponin T level is 0.4 ng/mL. Which of the following is the most likely diagnosis?
Acute myocardial infarction
Hypochondriasis
Prinzmetal’s angina
Stable angina
Unstable angina
A 91-year-old woman presents to the emergency department with a chief complaint of shortness of breath over the past 2 days. She has a history of hypertension and coronary artery bypass surgery 25 years earlier. Her blood pressure is 178/92 mm Hg and she has jugular venous distension, hepatomegaly, and 3+ lower extremity edema. ECG is remarkable for left ventricular hypertrophy, no ST-segment elevations or depressions, no Q waves, and no T wave abnormalities. Echocardiogram reveals an ejection fraction of 60% and left atrial dilatation. There is universal left ventricular thickening. No valvular regurgitation or stenosis was noted. Which of the following underlying conditions is the most likely cause of this patient’s symptoms?
Hypertensive heart disease
Hypertrophic obstructive cardiomyopathy
Ischemic heart disease
Mitral valve prolapse
Myocarditis
A 39-year-old white man with essential hypertension presents for a routine health maintenance visit. He has no complaints and reports compliance with his hydrochlorothiazide. His pulse is 70/min, blood pressure is 145/92 mm Hg, and respiratory rate is 16/min. His body mass index is 24 kg/m2. His physical examination is within normal limits. For which condition is the patient at increased risk?
End-stage renal disease
Hypercholesterolemia
Hypertrophic cardiomyopathy
Second-degree Mobitz I atrioventricular block
Type 2 diabetes mellitus
 
332
A 69-year-old woman complains of easy fatigue and one episode of presyncope. On examination of the jugular venous pressure (JVP), there are irregular large a waves. The ECG has fixed PP and RR intervals but varying PR intervals. Which of the following conditions is this most likely caused by?
Surgical removal of an atrium
Independent beating of atria and ventricles
A reentry phenomenon
A drug effect
A heart rate under 60 beats/min
A 47-year-old woman has new-onset transient right arm weakness and word finding difficulty symptoms lasting 3 hours. She is also experiencing exertional dyspnea, and had a syncopal event 1 month ago. Her echocardiogram reveals a cardiac tumor in the left atrium, it is pendunculated and attached to the endocardium. Which of the following is the most likely cause of this lesion?
Myxoma
Sarcoma
Rhabdomyoma
Fibroma
Lipoma
A 58-year-old man is undergoing cardiac catheterization for evaluation of chest pain symptoms. He is worried about the risks, and as part of obtaining informed consent, you advise him about the risks and benefits of the procedure. Which of the following aspects of angiography is true?
It is contraindicated in the presence of cyanosis
It is considered noninvasive
It is generally performed with cardiopulmonary bypass
It may cause renal failure
It requires carotid artery puncture
A 23-year-old man develops sharp left-sided chest pain, fever, and a friction rub heard at the lower left sternal border, unaffected by respiration. The pain is also aggevated by lying down and relieved by sitting up. He is otherwise well with no other symptoms and the remaining physical examination is normal. Which of the following is the most likely cause for his symptoms?
Rheumatic fever
Tuberculosis (TB)
Herpes simplex virus
MI
Coxsackievirus
A 55-year-old man with hypertension and a one-pack-per-day smoking history presents to the ED complaining of three episodes of severe heavy chest pain this morning that radiated to his left shoulder. In the past, he experienced chest discomfort after walking 20 minutes that resolved with rest. The episodes of chest pain this morning occurred while he was reading the newspaper. His BP is 155/80 mm Hg, HR 76 beats per minute, and RR 15 breaths per minute. He does not have chest pain in the ED. An ECG reveals sinus rhythm with a rate of 72. Which of the following best describes this patient’s diagnosis?
Troponin I is negative
Stable angina
Unstable angina
Non–ST-elevation MI
ST-elevation MI (STEMI)
 
337
A 58-year-old man is brought to the ED for a syncopal episode at dinner. His wife states that he was well until she found him suddenly slumping in the chair and losing consciousness for a minute. The patient recalls having some chest discomfort and shortness of breath prior to the episode. His rhythm strip, obtained by EMS, is shown below. Which of the following best describes these findings?
Mobitz type I
Mobitz type II
First-degree atrioventricular (AV) block
Atrial flutter with premature ventricular contractions (PVCs)
Sinus bradycardia
In the ICU, a patient suddenly becomes pulseless and unresponsive, with cardiac monitor indicating ventricular tachycardia. The crash cart is immediately available. What is the best first therapy?
Amiodarone 150-mg IV push
Lidocaine 1.5-mg/kg IV push
Epinephrine 1-mg IV push
Defibrillation at 200 J
Defibrillation at 360 J
A 70-year-old female has been healthy except for hypertension treated with a thiazide diuretic. She presents with sudden onset of a severe, tearing chest pain, which radiates to the back and is associated with dyspnea and diaphoresis. Blood pressure is 210/94. Lung auscultation reveals bilateral basilar rales. A faint murmur of aortic insufficiency is heard. The BNP level is elevated at 550 pg/mL (Normal < 100). ECG shows nonspecific ST-T changes. Chest x-ray suggests a widened mediastinum. Which of the following choices represents the best initial management?
IV furosemide plus IV loading dose of digoxin
Percutaneous coronary intervention with consideration of angioplasty and/or stenting
Blood cultures and rapid initiation of vancomycin plus gentamicin, followed by echocardiography
IV beta-blocker to control heart rate, IV nitroprusside to control blood pressure, transesophageal echocardiogram
IV heparin followed by CT pulmonary angiography
A 55-year-old African American female presents to the ER with lethargy and blood pressure of 250/150. Her family members indicate that she was complaining of severe headache and visual disturbance earlier in the day. They report a past history of asthma but no known kidney disease. On physical examination, retinal hemorrhages are present. Which of the following is the best approach?
Intravenous labetalol therapy
Continuous-infusion nitroprusside
Clonidine by mouth to lower blood pressure
Nifedipine sublingually to lower blood pressure
Intravenous loop diuretic
A 36-year-old male presents with the sensation of a racing heart. His blood pressure is 110/70, respiratory rate 14/minute, and O2 saturation 98%. His ECG shows a narrow QRS complex tachycardia with rate 180, which you correctly diagnose as paroxysmal atrial tachycardia. Carotid massage and Valsalva maneuver do not improve the heart rate. Which of the following is the initial therapy of choice?
Adenosine 6-mg rapid IV bolus
Verapamil 2.5 to 5 mg IV over 1 to 2 min
Diltiazem 0.25-mg/kg IV over 2 min
Digoxin 0.5 mg IV slowly
Electrical cardioversion at 50 J
 
342
Auscultation of the heart of a 17-year-old boy reveals an increased intensity of the pulmonary component of the second heart sound. He complains of dyspnea on exertion but no other cardiac or pulmonary symptoms. Which of the following explanations is the most likely cause of his dyspnea?
Pulmonary stenosis
Aortic stenosis
MI
Pulmonary hypertension
Systemic hypertension
 
343
A 22-year-old woman complains of palpitations and has a regular heartbeat at a rate of 170/min, with a blood pressure of 110/70 mm Hg. The rate abruptly changes to 75/min after applying carotid sinus pressure. Which of the following is the most likely diagnosis?
Sinus tachycardia
Paroxysmal atrial fibrillation
Paroxysmal atrial flutter
Paroxysmal supraventricular tachycardia (PSVT)
Paroxysmal ventricular tachycardia
 
344
A 58-year-old man with hypertension is brought to the emergency room after suddenonset chest pain that radiates to his back and arms. He is in moderate distress with a blood pressure of 160/90 mm Hg in the left arm and 120/70 mm Hg in the right arm. Cardiac examination reveals a soft second heart sound and a murmur of aortic insufficiency. His ECG shows sinus tachycardia but no acute ischemic changes, and the chest x-ray (CXR) Which of the following is the most appropriate next step in confirming the diagnosis?
Coronary angiography
Transthoracic echocardiography
Computerized tomography (CT) chest
Exercise stress test
Cardiac troponin level
A 17-year-old girl develops exertional dyspnea, but has no cough, sputum, or wheezing symptoms. On examination, she has a fixed splitting of her second heart sound and a 3/6 systolic ejection murmur heard best over the left sternal border. An echocardiogram confirms the condition. Which of the following is the best physiologic explanation for her condition?
Pulmonary blood flow is greater than systemic blood flow
Pulmonary blood flow is less than systemic blood flow
Pulmonary blood flow is equal to systemic blood flow
The left ventricle is enlarged
The systemic blood pressure is elevated
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