The Bioanalysis Glossary Quiz
 
Test your knowledge of ten terms from The Bioanalysis Glossary.
 
There will be ten definitions, with a choice of four words beneath, pick the correct term for your chance to win a luxury Fortnum and Mason food basket!

Assay using antibodies to detect or quantify an analyte
Diagnostic assay
Immunoassay
Immunogenicity assay
Flow cytometry
The measurement of all low-molecular-weight metabolites and their intermediates in a biological system
Metabolite profiling
Metabonomics
Metabolite features
Metabolome coverage
A comprehensive set of experiments to investigate whether an analytical method is functioning according to predefined acceptance criteria. For regulated bioanalysis, criteria should be in compliance with guidelines published by regulatory authorities
Method qualification
Cross-validation
Method validation
Regulatory validation
The direct or indirect alteration or interference in instrumental response due to the presence of matrix constituents in extracted samples or unextracted samples, which the overall method selectivity is inadequate to address
Matrix factor (MF)
Post-column infusion
Matrix effect
Hemolytic effect
Mass analyzer that utilizes a field-free vacuum chamber to separate ions by their velocity. The time-of-flight is then converted into the accurate mass of the observed ion
Tandem quadrupole mass spectrometry
Time-of-flight mass spectrometry
Accelerator mass spectrometry
Ion trap mass spectrometry
The relationship between drug concentration at the site of action (receptor) and pharmacologic response, including biochemical and physiologic effects that influence the interaction of drug with the receptor
Pharmacokinetics
Pharmacodynamics
Therapeutic drug monitoring
Bioavailability
Activities undertaken within the quality management system to verify that operational activities and derived data have been verified
Good manufacturing practice
Quality assurance
Good laboratory practice
Quality control
The volumetric proportion of red blood cells in blood
Hematocrit
Blood:plasma distribution ratio
Whole blood
Serum
Sample of blood or any other biological matrix in the low μl/μg range utilized for certain preclinical or clinical studies, particularly with small animals or children
Dilution QC sample
Predose sample
Microsample
Processed sample
Means of sample extraction that relies on the partitioning of an analyte between an aqueous component and a water-immiscible organic component
Supported-liquid extraction
Online extraction
Recovery (extraction)
Liquid-liquid extraction
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