Drug cards Group 2
Clopidogrel therapeutic use
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of clopidorel
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions with clopidorel
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for clopidorel
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Alteplase therapeutic effects
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of alteplase
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions with alteplase
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for alteplase
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Altorvastatin therapeutic use
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions for atorvastatin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for atorvastatin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Cholestyramine therapeutic uses
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Administration of cholestyramine
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for cholestyramine
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Fenofibrate therapeutic uses
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of fenofibrate
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions for fenofibrate
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for fenofibrate
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Ezetimibe therapeutic uses
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Administration of ezetimibe
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for ezetimibe
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Niacin therapeutic use
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of niacin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions with niacin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for niacin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Digoxin therapeutic uses
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of digoxin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for digoxin
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Milrinone lactate therapeutic use
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Adverse effects of milrinone lactate
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Med interactions for milrinone lactate
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Nesiritide therapeutic uses
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
Education for nesiritide
Taken once everyday, taken at night if combined with statin, either 2hr before or 4 hr after bile sequestrates, monitor lipid response
Alcohol, leflunomide, statins, zidovudine, bile acid sequestriants
Narrow therapeutic window can leave to toxicity, headache, weakness, arrhythmias, GI upset
Decrease total serum cholesterol, LDL, and triglycerides, treats hypercholesterolemia
Reduce LDL
Used with dietary management for treating primary dyslipidema, reduces total cholesterol, triglyceride and increases HDL
Gi discomfort, diarrhea, may also increase cholesterol in billiard track and formation of gallstones
May enhance warfarin-type oral anticoagulants, statins, cyclosporine
Indications for use include MI, stroke, vascular death. Do not double meds if does is missed
Skin flushing, pruritus, gastric irritation, tachycardia, hypotension, dizziness, hyperglycemia, hyperuricemia
Tablet strengths are NOT interchangeable
Assess for dysrhythmias, report any evidence of bleeding, take special care when brushing teeth
Bowel program may be needed for constipation, ensure its not taken in dry form, good dental hygiene, these drugs are used to lower LDL further in those already taking a statin drug
Not compatible with other meds, do not take furosemide in same IV line
Development of potentially fatal ventricular dysrhythmias, hypotension, angina, thrombocytopenia, hypoalemia
Woman should receive contraception, monitor liver function daily, look for lipid levels and increased HDL
May cause hepatotoxicity, necessary to monitor liver, periodic blood tests, report chest pains, shortness of breath, palpitations, myalgia, malaise, excessive fatigue, fever
Magnesium and aluminum containing antacids, avoid grapefruit
Management of heart failure, atrial fibrillation, and atrial flutter
Not recommended for moderate-severe hepatic impairment, shouldn't be taken during pregnancy or lactation, maintain low cholesterol diet, periodic blood tests
Most effective for increasing HDL, most helpful in preventing heart disease in combo with dyslipidemic, used with statin can lower LDL
Degrades fibrin clots, lyses thrombi and emboli, treats acute ischemic stroke, minimize ischemic time and restores blood flow
Mix powder with water or other fluids, observe lipid levels
Toxicity develops more often and lasts longer with renal impairment, assess for edema daily, observe for pulmonary congestion
Pruritis, rash, purpura, diarrhea
Bleeding, cardiac arrhythmias with coronary repefusion, hypotension
Reduces serum triglyceride values, also helps in low HDL cases
Short term management for acute-severe heart failure for those who don't respond to digoxin, diuretics or vasodialators
Increase risk of bleeding when taken with NSAIDs, may be taken with aspirin, no garlic, ginkgo, ginger, green tea
Heparin, aspirin, and dipyridamole increase risk of hemorrhage
Reduces cardiac preload and after load (used in decompensated patients with acute HF)
Frequent monitoring for BP nd pulse, bed rest maintained, bolus does for continuous infusion, report numbness, shortness of breath or chest pain
Inhibits platelet aggregation (antiplatlet activity)
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