Clinical Chemistry

A Gaussian distribution is usually
Rectangular
Uniform
Skewed
Bell-shaped
For a data value set that is Gaussian distributed, what is the likelihood (%) that a data point will be within +/-1 SD from the mean?
68%
99%
95%
100%
The variance is expressed as:
The square of the standard deviation
Summation of the square of the difference of the mean and the value divided by the number of data
The difference of the mean and the value squared
All of the above
Ability of a method to detect small quantities of an analyte
Analytical Specificity
Analytical Sensitivity
Specificity
LOD
Ability of a method to detect only the analyte it is designed to determine
Analytical Sensitivity
Analytical Specificity
Specificity
LOD
Ability of a method to measure only the analyte of interest
Analytical Sensitivity
Analytical Specificity
Specificity
LOD
Range of analyte concentrations that can be directly measured without dilution or concentration.
AMR
CRR
LOD
AS
Range of analyte that a method can quantitatively report, allowing for dilution and concentration used to extend AMR
AMR
CRR
LOD
AS
Lowest amount of analyte accurately detected by a method
AMR
CRR
LOD
AS
Dispersion of repeated measurements about the mean due to analytic error.
Imprecision
Inaccuracy
Method Selection
All of the above
Inaccuracy
Random Error
Systemic Error
Imprecision
Random Error
Systemic Error
Reference range of glucose
80 mg/dl
150 mg/dl
70 mg/dl
65 mg/dl
Hypoglycemia reference range
80 mg/dl
50 mg/dl
70 mg/dl
65 mg/dl
Hyperglycemia reference range
80 mg/dl
150 mg/dl
70 mg/dl
65 mg/dl
Used to detect errors in accuracy and imprecision over time
Levey-Jennings Control Chart
Quality Control
Calibration
None of the above
The interfering reducing substances in the Folin-Wu glucose method may be removed by:
Dialysis
Heating
Zinc-Barium Precipitation
all of the above
Contamination of the glucose reagent with catalase is a problem with which glucose method?
Alkaline cupric ion reduction (neocuproine)
Alkaline ferric iron reduction (ferricyanide)
Glucose Oxidase
Hexokinase
Which of the following is true about blood glucose?
The renal threshold is 200-240 mg/dl
Once excreted in the glomerular filtrate, glucose must be excreted in the urine
A high blood glucose must be assiociated with a positive glucose
In the glucose tolerance test (GTT)l one may be faced with a normal blood glucose, accompanied by a positive urine glucose
A urine specimen that exhibits yellow foam on being shaken should be suspected of having increased concentration of:
Ketones
Glucose
Bilirubin
Nitrite
Which of the following precautions is necessary to insure validity of the glucose tolerance test?
A 150 gram/day carbohydrate diet for 3 days prior to the test
A fasting state before glucose is given
No undue stress before or during the test
All of the above
Agreement of results with true value for substance in given specimen
Accuracy
Precision
Reliability
All of the above
Ability to produce series of results that agree closely with each other
Accuracy
Precision
Reliability
None of the above
Measure of the ability to achieve accuracy and precision
Relability
Quality Control
Quality Assurance
None of the above
The minimum number of analytes in quality control
15
20
25
30
Mean is the:
Sum of all value over n
Sum of all value over the number of value minus 1
Σx/n
a and c
all of the above
What coagulant is used for whole blood? (color of the tube)
Green
Lavander
Red
None of the above
Coagulant used for OGTT? (color of the tube)
Green
Lavander
Lavander
None of the above
What specimen is used for OGTT?
Serum
Plasma
a and b
none of the above
The hormone released during physical and emotional stree?
Epinephrine
Adrenaline
a and b
none of the above
Site of synthesis for the growth hormone?
Anterior pituitary gland
Pars Distalis
a and b
none of the above
Glucose is primarily stored in:
blood
spleen
thyroid
none of the above
The following causes hypoglycemia EXCEPT:
Insulinoma
Islet hyperplasia
slight exercise
Von Gierke Disease
Gives an arsenomolybdenum blue positive reaction:
Nelson Somogyi
Copper Reduction Method
Glucose Oxidase
a and b
Also known as Copper Reduction Method:
Nelson Somogyi
Hagedorn Jensen
Dubowski
Folin-Wu
0
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