Histology 2E

Create an illustration of human lymphatic and immune system diagrams, highlighting organs like the thymus, spleen, and lymph nodes in an educational style.

Histology 2E Quiz

Test your knowledge of the lymphatic and immune systems with our comprehensive Histology 2E quiz. This interactive quiz covers a wide range of topics, including the adaptive immune response, lymphatic organs, and antigen-presenting cells.

  • Engaging multiple-choice questions
  • Designed for students and professionals
  • Enhance your understanding of human biology
29 Questions7 MinutesCreated by LearningCell102
What is true regarding the adaptive immunity?
Its response is very rapid
Includes antigen presenting cells
Includes the action of B-lymphocytes
Is evolutionary older than acquired immunity
It could be because of the exsintence of IgA within saliva or tears
Is because of clonal expansion of B-cells
Is because of action of lysozymes
Which organs of the lymphatic system are unencapsulated?
Palatine tonsils
Peyer's patches
Solitary nodules
Thymus
GALT
Lymph nodes
Which statement regarding the lymphatic system is true?
Penicillar arterioles are typical for the thymus
HEV's are present in lymph nodes
Spleen contains an outer cortex
Secondary lymphatic nodules have a germinal center
Appendix is the so-called tonsil of the digestive tract
Open blood circulation is specific for lymph nodes
Palatine tonsils are covered by pseudostratified epithelium
What is correct for the thymus?
The thymus belongs to the central lymphoid organ
Produces immunoglobulins
Its stroma is composed of connective tissue
Does not contain a connective tissue capsule
Is covered by a connective tissue capsule
Is covered by simple squamous epithelium
Contains a lot of lymph nodes
Undergoes involution during postnatal life
Blood-thymus barrier in the cortex
Contains white pulp
Which organ of the lymphatic system is capsulated?
Thymus
Lymph node
Spleen
Bone marrow
GALT
Which organ of the lymphatic system is unencapsulated?
Thymus
Solitary nodules
Palatine tonsil
Lymph node
Thymus:
Belongs to the central lymphoid organs
Its epithelial cells are antigen-presenting
Its stroma consists of epithelial cells
Blood-thymus barrier in the medulla
What is correct for the lymphatic system?
Open blood circulation is specific for the spleen
HEV's are present in lymph nodes
Lymphatic nodule of lymph node has a central arteriole
Lymphatic nodule of the spleen has a central arteriole
Penicillar arterioles are typical for the spleen
The spleen is the organ of red blood cell degradation
Secondary lymphatic nodules have a germinal center
Unencapsulated lymphoid organs:
Palatine tonsil
MALT
GALT
Solitary nodules
Peyer's patches
Antigen-presenting cells:
They process antigens and show them to T-lymphocytes
They have MHC 1 and 2 on their surface
Includes dendritic cells of lymphatic nodules
Includes langerhans cells of skin; dermis
Are part of the mononuclear phagocyte system
Are MHC restricted cells
Are not restricted by MHC
Lymphatic system:
Lymphatic nodule of lymph node has a central arteriole
Open blood circulation is specific for the spleen
HEV's are present in the inner cortex of lymph nodes
Adaptive immunity:
Includes the action of B-lymphocytes
It could be because of the existence of IgA within saliva and tears
Is because of the phagocytic activity of neutrophils
Is because of the action of lysosomes
Includes antigen presenting cells
Is because of clonal expansion of B-lymphocytes
Lymph nodes:
Are distributed along the course of lymphatic vessels
T-lymphocytes are situated in the paracortex
Contains lymphatic sinuses
Becomes larger during inflammation
Germinal center is part of the inner cortex
Lymph vessels enter at the convex side
Has not got any T-helper cells
Plasma cells in medullary cords
What is correct regarding the lymphatic system?
Antibodies are produced by plasma cells
Th-lymphocytes belong to the CD4 positive cells
Closed blood circulation is possible for the spleen
Open blood circulation is specific for the spleen
The spleen:
Is the biggest lymphoid organ
Its stroma is formed by reticular connective tissue
Red pulp is composed of splenic cords and T&B-cells
There are no B-lymphocytes
PALS of white matter contains B-cells
White pulp contains B-lymphocytes, PALS and central artery
PALS of white matter is the thymus dependent zone
It is a central lymphoid organ
Lymphatic organs:
Includes the central and peripheral organs
The bone marrow is the central organ for B-lymphocytes
The germinal center of lymphoid nodules contains mainly B-lymphocytes
Matches: description of the lymphatic organ
Lymph node - cortex with lymphatic nodules
Thymus - reticular epithelial stroma
Spleen - thymus dependent zone is PALS
Lymph node - outer cortex is thymus dependent
Lymph node - inner cortex is thymus dependent
Lymph node - outer cortex is thymus independent
True regarding the lymphatic system:
IgA is a secretory immunoglobulin
APC include dendritic cells
Thymus is the central lymphatic organ for T-lymphocytes
Spleen is covered with simple squamous epithelium
White pulp of spleen is composed of lymphatic nodule
Immunoglobulins
There are five classes in humans; IgG, IgA, IgM, IgE and IgD
IgG is the most abundant in serum
Are manufactured by plasma cells
IgA is a secretory antibody
IgE, IgG and IgD are monomer
IgA is a dimer
IgM is a pentamer
Antigen-presenting cells: APCs
Are found in many tissues
Includes macrophages
Includes dendritic cells
Langerhans cells are not regarded as APCs
They have on their surface MHC1 and MHC2
Include B-cells
Thymus:
Is a lympho-epithelial organ
Does not have lymphatic nodules but incomplete lobules
Hassals corpuscles are located in its medulla
Hassals corpuscles:
Are found in the medulla of the thymus
Are formed by TECs
Are degenerated epithelial cells
Immune response:
T-lymphocytes are responsible for the cellular mediated immune response
B-lymphocytes are responsible for the humoral mediated immune response
Innate immunity is rapid from start
Adaptive immunity starts slow then rapid
The lymph node:
Is the place of B-cell proliferation
Possesses afferent and efferent lymphatic vessels
Outer cortex contains lymphatic nodule
Outer cortex contains PALS
Are avascular
Lymph vessel enter the concave depression
Lymph vessel enter the convex side
Its stroma is formed by reticular connective tissue
Germinal center is part of its outer cortex
Unencapsulated lymphoid organs:
Appendix
Tonsils
Peyer's patches
Solitary lymphoid nodules
What is true about the thymus?
Has not got any lymphatic nodules
Belongs to the central lymphoid organ
Is medulla contains thymocytes cortex
Filters lymph from antigens
Produces immunoglobulins
Undergo involution during postnatal life
Antigen presenting cells:
Have phagocytic ability
Macrophages are an example of these cells
They only have MHC2 on their surface, not MHC1
Includes dendritic cells of lymphatic nodules
Processes antigens and shows them to T-lymphocytes
Produces only IgA among the immunoglobulins
Are MHC restricted cells as T-lymphocytes
Spleen:
Red pulp is composed of splenic cords and sinusoids
White pulp includes lymphoid nodule, central artery and PALS
Its capsule contains smooth muscle cells
Is divided into a medulla and cortex
Is a central lymphoid organ
Its stroma is formed by epithelial reticular cells
What is true for the lymphoid system?
HEV's are present in the inner cortex of lymph nodes
Secondary lymphatic nodules have a germinal center
The mantle of secondary lymphatic nodules contain mature B-lymphocytes
Tonsils does not have a thymus-dependent zone
Payers patches are situated in the duodenum
Payers patches are situated in the appendix
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