Immunologi

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Immunology Mastery Quiz

Test your knowledge and understanding of immunology with this comprehensive quiz. Dive into various topics, from hypersensitivity to autoimmune diseases, and challenge yourself with 30 thought-provoking questions.

Whether you're a student, educator, or just an enthusiast, this quiz can help enhance your grasp of immune system concepts.

30 Questions on Immunology
Multiple Choice Format
Engaging Learning Tool

30 Questions8 MinutesCreated by TestingTree135

3.Lymphocytes anergy is provoked by:

A) attenutation signal

B) lacking antigen recognition by TCR

C) lacking costimulatory molecules signal

D) lacking connection between the adhesive molecules

E) amino acids change in the antigen recognized by T lymphocytes

4.Which of the tests would you not use in hypersensitivity type I diagnostics:

5. Which pf the following does not belong to autoimmune diseases?

6.Which of the following represent central tolerance induction mechanisms?

8.Type III hypersensitivity is involved in the pathomechanism of the following

9. Which of the following best describes type I hypersensitivities

A) complement-dependent lysis of cells

b)the release of physiological mediators from IgE-bound mast cells and basophils

C) the formation of immune complexes that are deposited on basement membranes

D) the reaction of T CD4+ cells, cytokines, and macrophages

E) cytotoxic cells taking part in ADCC reaction

10.When type B blood is given to a person with type A blood

A) B antigen from the donor reacts with anti-A antibody in the recipient

B) B antigen from the recipient reacts with anti-B antibody in the donor

C) A antigen from the donor reacts with anti-A antibody in the recipient

D) B antigen from the donor reacts with anti B antibody in the recipient

E) no reaction occurs

5. Which of the following belong to hematological manifestations of type II hypersensitivity?

A) blood transfusion-related reaction (group complex incompatibile)

B) newborns haemolytic disease

C) autoimmune hamolytic anaemias

10. Which of the following represent effectory mechanisms of type II hypersensitivity?

Choose false sentence relating to the Coombs test

1. Direct Coombs test is applied in case of newborn hemolytic disease

2. Indirect coombs test detects incomplete anti-RhD antibodies coated on newborn’s erythrocytes

3. Antiglobulin antibodies aren’t required in this test

4. Direct and indirect Coombs test are based on precipitation reaction

5. Direct Coombs test is applied for RhD negative mother in suspicion of serological incompatibility between mother and child

4. Choose true informations about cross-match test

1. Based on molecular methods, performed once before transplantation, checks the presence of performed anti-HLA antibodies directed against donor

2. Based lymphocytotoxic test, performed once directly, checks the presence of preformed anti-HLA antibodies directed against donor

3. Based on precipitation test, performed once before transplantation, checks the level of recipient’s alloimmunization

4. Based on lymphocytotoxic test, repeated every 3 months during waiting for transplantation, checks the presence of anti-HLA antibodies directed against donor

5. Based on lymphocytotoxic test, repeated every 3 months during waiting for transplantation, checks the level of recipient’s alloimmunization

5. Choose false about correct criteria which should be respected before kidney transplantation

A)Positive result of virtual cross-matches, at least 50% HLA compatibility between donor and recipient

B) Identical blood group between donor and recipient, negative result of cross- match reaction

C) Negative result of biological and virtual cross-matches, 50% HLA compatibility between donor and recipient

D) Identical blood group between donor and recipient,

Choose false sentence about lymphocytotoxic test test

A) Based on complement fixation test

b) This test is performed only for the recipient

C) Checks the level of anti-HLA antibodies in recipient’s serum

D) Performed only before transplantation

E) Helps to avoid acute rejection

7. Choose correct pairs between TAA and carcinoma

1. PSA – prostatic cancer, CALLA –chronic myeloblastic leukemia, HPV – cervical carcinoma

2. EBV - Burkitt´s lymphoma, AFP-hepatomas, CEA- colorectal carcinoma

3. CALLA – chronic myeloblastic leukemia, Bence-Jones protein – multiple myeloma, AFP – primary liver cancer

4. CEA – pancreatic carcinoma, CALLA – acute lymphoblastic leukemia, Ca-199 – multiple myeloma

5. Ca-125 – ovarian carcinoma, PSA – prostatic cancer, Bence-Jones protein – Burkitt’s lymphoma

8. Keeps pregnancy on proper course, required for tryptophan degradation, responsible for T cells “starvation”?

9. Which mechanism facilitates tumor growth?

A) Immunological surveillance

B) Antigenic heterogenecity

C) Presence of IDO enzyme in host cells

D) Presence of TAA on tumor cells

E) Presence of MHC molecules on host cells

1. Which of the assays is NOT applied in the quantitative antibodies assessment?

2. Choose true about RIST/RAST

A) these represent immunoenzymatic assays

B) these are applied in the assessment of intracellular killing

C) these represent radioimmunologic assays

D) these are not immunologic assays

E) these are applied in the assessment of specific IgA

4. Choose true about Western blot

A) this is a quantitative assay based on colour reaction

B) this is a quantitative assay based on radiometric reaction

C) this is a quantitative assay based on radiometric reaction

D) none

E) this is an example of qualitative assay based on colour reaction

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