BMS 506 Lecture 7

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(True or False) Activation of lymphocytes occurs in secondary lymphoid organs such as the thymus. (1 pt.)

Previously activated T cells are less dependent on costimulatory molecules. (1 pt.)

It is expressed constitutively on dendritic cells:

CD4+ Th2 signature cytokine:

Models for thymic Treg cell development: i. Instructive, ii. Conventional, iii. Stochastic, iv. Selective, v. General, vi. Standard

What is/are the mechanism(s) of CTL mediated killing: i. Antibody, ii. Perforin, iii. Complement, iv. Granzyme, v. Fas/FasL

CD4+ Th1 signature cytokine:

CTLA-4 plays a role in the positive regulation of immune responses.