CARDIVA Online Quiz

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.

____________________ is a potent vasoconstrictive peptide that causes blood vessels to narrow, resulting in increased blood pressure

__________________ causes the renal tubules to increase the reabsorption of sodium and water into the blood, while at the same time causing the excretion of potassium. This increases the volume of extracellular fluid in the body, which also increases blood pressure.

If the RAS is abnormally active, blood pressure will be too high

Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.

____________________ is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

The GFR formula includes some or all of the following:

In adults, the normal GFR number is 50 or lower. Having a GFR between 60 and 89 may be abnormal for some people, including those over age 60.

A major goal of treatment for patients with type 2 diabetic nephropathy is to prevent or slow the progression to ESRD. Effective antihypertensive treatment reduces MAU in hypertensive patients with diabetes and helps slow the progression of diabetic nephropathy. Early intervention can affect outcome.

What is the Peak plasma concentrations of Irbesartan?

What is the elimination half-life of Irbesartan?

What are the indications for Irbesartan?

Irbesartan is indicated for Pregnant women up to the 3rd Trimester because it is the safest ARB.

Irbesartan offers the following benefits, except for:

Irbesartan is approved for initial therapy and in patients to achieve BP goals. Moreover, reduction in BP is significantly greater with Irbesartan/HCTZ than with either Irbesartan or HCTZ as monotherapy.