CARDIVA Online Quiz
CARDIVA Online Quiz
Test your knowledge about the renin-angiotensin system, its role in blood pressure regulation, and the therapeutic effects of Irbesartan. This comprehensive quiz covers key concepts and helps you understand the physiological mechanisms at play.
- Learn about the fundamentals of RAS
- Discover the importance of GFR in kidney fun
ction - Explore the benefits and indications of Irbesartan therapy
The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
True
False
____________________ is a potent vasoconstrictive peptide that causes blood vessels to narrow, resulting in increased blood pressure
Angiotensin II
Potassium
Prorenin
Sodium
__________________ causes the renal tubules to increase the reabsorption of sodium and water into the blood, while at the same time causing the excretion of potassium. This increases the volume of extracellular fluid in the body, which also increases blood pressure.
Renin
Aldosterone
Serotonin
Prorenin
If the RAS is abnormally active, blood pressure will be too high
True
False
Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.
True
False
____________________ is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.
Epoetin beta Filtration rate
Glomerular Filtration Rate
Renin Filtration rate
Sodium Filtration rate
The GFR formula includes some or all of the following:
Age and Blood creatinine measurement
Ethnicity and Gender
Height and Weight
All of the above
In adults, the normal GFR number is 50 or lower. Having a GFR between 60 and 89 may be abnormal for some people, including those over age 60.
True
False
A major goal of treatment for patients with type 2 diabetic nephropathy is to prevent or slow the progression to ESRD. Effective antihypertensive treatment reduces MAU in hypertensive patients with diabetes and helps slow the progression of diabetic nephropathy. Early intervention can affect outcome.
True
False
What is the Peak plasma concentrations of Irbesartan?
30 minutes
10 hours
45 minutes
1.5 to 2 hours
What is the elimination half-life of Irbesartan?
4 to 5 hours
11 to 15 hours
8 to 9 hours
2 to 3 hours
What are the indications for Irbesartan?
Essential hypertension
Uncontrolled Hypertension
Diabetic nephropathy
All of the above
Irbesartan is indicated for Pregnant women up to the 3rd Trimester because it is the safest ARB.
True
False
Irbesartan offers the following benefits, except for:
Slows progression to renal disease
Enhanced clinical efficacy
Bioavailability is higher than all other ARBs and Bioequivalent to innovator
Recommended for Pediatric patients
Irbesartan is approved for initial therapy and in patients to achieve BP goals. Moreover, reduction in BP is significantly greater with Irbesartan/HCTZ than with either Irbesartan or HCTZ as monotherapy.
True
False
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