Would DATTs (Device Assisted Treatments and Therapies) benefit me?

What do I do when I feel like my medications are not working well?
 
The first answer to this is always to speak to your doctor. They can help you optimise your medication, and will also be able to give you personalised advice on any treatment options that are appropriate for you.
 
While you're waiting to speak to your doctor, feel free to use this tool to find out more about Device Assisted Treatments and Therapies (or DATTs), and help you prepare questions to ask your healthcare professional.
 
Tick the box below to proceed.
What do I do when I feel like my medications are not working well?
 
The first answer to this is always to speak to your doctor. They can help you optimise your medication, and will also be able to give you personalised advice on any treatment options that are appropriate for you.
 
While you're waiting to speak to your doctor, feel free to use this tool to find out more about Device Assisted Treatments and Therapies (or DATTs), and help you prepare questions to ask your healthcare professional.
 
Tick the box below to proceed.
I understand that I should speak to my doctor about any healthcare issues, and would like to find out more about treatment options in the meantime.
What non-tablet treatments are there?
 
There are non oral treatment options that are commonly called Device Assisted Treatments and Therapies (DATTs).
 
! TECHNICAL TERM KLAXON !
Throughout this guide, we use the term Device Assisted Treatments and Therapies (DATTs) to encompass a range of treatment options for advanced Parkinson's. We're using this term because doctors and other clinicians use it – so you might find it helpful to use it when you’re speaking to your own healthcare professionals.
 
Click "Next" to find out more.
What non-tablet treatments are there?
 
There are non oral treatment options that are commonly called Device Assisted Treatments and Therapies (DATTs).
 
! TECHNICAL TERM KLAXON !
Throughout this guide, we use the term Device Assisted Treatments and Therapies (DATTs) to encompass a range of treatment options for advanced Parkinson's. We're using this term because doctors and other clinicians use it – so you might find it helpful to use it when you’re speaking to your own healthcare professionals.
 
Click "Next" to find out more.
What are some examples of Device Assisted Treatments and Therapies (DATTs)?
 
Click the options below to find out more about each type of DATT.
Deep Brain Stimulation
Injection pen
Pumps
MR-guided Focused Ultrasound
Skip question

Deep Brain Stimulation

 

Copy of Parkinson's Life header images.png

 

Deep Brain Stimulation (or DBS) is the most common surgical treatment for Parkinson’s, with more than 200,000 patients implanted worldwide so far.

 

How does DBS work?

It uses a small, pacemaker-like device (stimulator) to send electronic signals to a precise area in the brain that controls movement via very thin wires (leads). Stimulation of these areas appears to block the brain messages that cause disabling motor symptoms and so can provide greater symptom control.

The stimulator is usually implanted in your chest or abdomen, with leads going up through your neck and linked to electrodes implanted in the brain. The stimulator uses a battery which can be rechargeable or non-rechargeable. The procedure is fully reversible.

 

What are the benefits and risks of DBS?

The most common benefits of DBS are reduction of Parkinson’s motor symptoms including rigidity and tremor, reduction in medication intake and overall increased quality of life.

Risks of DBS are linked to surgery complication and post-operation infections, similarly to any other surgery, as well as to possible side effects such as changes in voice and personality.

 

The development of DBS

Since its first use in the late 1980s, Deep Brain Stimulation has been continuously developed further, with recent innovations including remote programming, sensing for amplitude adaptation and next-generation directional leads programable with an image-guided interface.

Since movement disorders such as Parkinson’s aren’t static, DBS systems can be adjusted – or programmed – to adapt to the evolving needs of the patient.

 

Find out more

Find out more from the companies that produce DBS devices:

Press "Back" below to return to the previous screen, or click "Next" to find out about Pens.

Deep Brain Stimulation

 

Copy of Parkinson's Life header images.png

 

Deep Brain Stimulation (or DBS) is the most common surgical treatment for Parkinson’s, with more than 200,000 patients implanted worldwide so far.

 

How does DBS work?

It uses a small, pacemaker-like device (stimulator) to send electronic signals to a precise area in the brain that controls movement via very thin wires (leads). Stimulation of these areas appears to block the brain messages that cause disabling motor symptoms and so can provide greater symptom control.

The stimulator is usually implanted in your chest or abdomen, with leads going up through your neck and linked to electrodes implanted in the brain. The stimulator uses a battery which can be rechargeable or non-rechargeable. The procedure is fully reversible.

 

What are the benefits and risks of DBS?

The most common benefits of DBS are reduction of Parkinson’s motor symptoms including rigidity and tremor, reduction in medication intake and overall increased quality of life.

Risks of DBS are linked to surgery complication and post-operation infections, similarly to any other surgery, as well as to possible side effects such as changes in voice and personality.

 

The development of DBS

Since its first use in the late 1980s, Deep Brain Stimulation has been continuously developed further, with recent innovations including remote programming, sensing for amplitude adaptation and next-generation directional leads programable with an image-guided interface.

Since movement disorders such as Parkinson’s aren’t static, DBS systems can be adjusted – or programmed – to adapt to the evolving needs of the patient.

 

Find out more

Find out more from the companies that produce DBS devices:

Press "Back" below to return to the previous screen, or click "Next" to find out about Pens.

Injection pen

 

parkinsons-injection-pen.jpg

 

What is an injection pen for Parkinson's treatment?

An injection pen is a device designed to provide you with a self-administered injection of the Parkinson’s medication apomorphine. This reduces the length of an OFF periods and the associated symptoms.

An injection pen system is normally composed of:

  • A pen, which features a wheel for adjusting medication dose and a display
  • Disposable needles
  • Cartridges containing the apomorphine medication

Injections can be self-managed or with the help of a caregiver. Injection sites are normally on your thigh, upper arm, or abdomen.

 

What are the benefits and risks of an injection pen?

The benefits of using an apomorphine injection pen are fast reduction of OFF periods and control of associated symptoms compared to oral tablets.

Common risks are related to skin reactions and possible infections, and difficulties in performing the injection by yourself or a caregiver.

 

Find out more

Find out more about injection pens from the companies supporting pen devices:

Press "Back" below to return to the previous screen, or click "Next" to find out about Pumps.

Injection pen

 

parkinsons-injection-pen.jpg

 

What is an injection pen for Parkinson's treatment?

An injection pen is a device designed to provide you with a self-administered injection of the Parkinson’s medication apomorphine. This reduces the length of an OFF periods and the associated symptoms.

An injection pen system is normally composed of:

  • A pen, which features a wheel for adjusting medication dose and a display
  • Disposable needles
  • Cartridges containing the apomorphine medication

Injections can be self-managed or with the help of a caregiver. Injection sites are normally on your thigh, upper arm, or abdomen.

 

What are the benefits and risks of an injection pen?

The benefits of using an apomorphine injection pen are fast reduction of OFF periods and control of associated symptoms compared to oral tablets.

Common risks are related to skin reactions and possible infections, and difficulties in performing the injection by yourself or a caregiver.

 

Find out more

Find out more about injection pens from the companies supporting pen devices:

Press "Back" below to return to the previous screen, or click "Next" to find out about Pumps.

Infusion pumps

 

 

What is an infusion pump?

A pump is a device designed to provide you with a continuous infusion of Parkinson's medicine via a needle inserted in your small intestine or under your skin.

This allows the medicine to bypass the gastrointestinal tract and be absorbed more rapidly by your body, reducing the fluctuations and wearing off linked to oral tablets.

The Parkinson’s medications delivered via a pump system are:

  • Levodopa/Carbidopa (delivered either in the small intestine or under the skin)
  • Levodopa/Carbidopa/Entacapone (delivered in the small intestine)
  • Apomorphine (delivered under the skin)

A pump system is normally composed of:

  • The pump device, which can include a reservoir for the medication
  • A needle, which can be inserted either in your small intestine (with a small surgical procedure) or under your skin (self-managed) and then removed, leaving
  • A cannula (thin tube) in the intestine or under the skin for the medication to be delivered through
  • Vials, cassettes or cartridges containing the medication

The pump device is normally worn attached to your belt or in a dedicated case/bag.

Pump devices have a display and button to control settings and adjust the medication flow.

Medication dose change will always be managed by a clinician.

 

The-CRONO-LECIG-pump-system-and-the-position-of-the-tube-system.png

 

What are the benefits and risks of using an infusion pump?

The benefits of using a pump are the reduction of fluctuations linked to the wearing off of medication doses and the more stable controlling of Parkinson’s symptoms.

Common risks are related to skin reactions and possible infections on the infusion site, and difficulties in handling the pump by yourself or a caregiver.

 

Where to find out more

Find out more from the companies which produce infusion pump devices:

  • Levodopa/Carbidopa pump for infusion in the small intestine
  • Levodopa/Carbidopa pump for infusion under the skin

Britannia Pharmaceuticals

  • Apomorphine pump for infusion under the skin
  • Levodopa/Carbidopa/Entacapone pump for infusion in the small intestine
  • Infusion set for apomorphine pump and levodopa/carbidopa

EVER Pharma

  • Apomorphine pump for infusion under the skin
 
Press "Back" below to return to the previous screen, or click "Next" to find out about MR-Focused Ultrasound.

Infusion pumps

 

 

What is an infusion pump?

A pump is a device designed to provide you with a continuous infusion of Parkinson's medicine via a needle inserted in your small intestine or under your skin.

This allows the medicine to bypass the gastrointestinal tract and be absorbed more rapidly by your body, reducing the fluctuations and wearing off linked to oral tablets.

The Parkinson’s medications delivered via a pump system are:

  • Levodopa/Carbidopa (delivered either in the small intestine or under the skin)
  • Levodopa/Carbidopa/Entacapone (delivered in the small intestine)
  • Apomorphine (delivered under the skin)

A pump system is normally composed of:

  • The pump device, which can include a reservoir for the medication
  • A needle, which can be inserted either in your small intestine (with a small surgical procedure) or under your skin (self-managed) and then removed, leaving
  • A cannula (thin tube) in the intestine or under the skin for the medication to be delivered through
  • Vials, cassettes or cartridges containing the medication

The pump device is normally worn attached to your belt or in a dedicated case/bag.

Pump devices have a display and button to control settings and adjust the medication flow.

Medication dose change will always be managed by a clinician.

 

The-CRONO-LECIG-pump-system-and-the-position-of-the-tube-system.png

 

What are the benefits and risks of using an infusion pump?

The benefits of using a pump are the reduction of fluctuations linked to the wearing off of medication doses and the more stable controlling of Parkinson’s symptoms.

Common risks are related to skin reactions and possible infections on the infusion site, and difficulties in handling the pump by yourself or a caregiver.

 

Where to find out more

Find out more from the companies which produce infusion pump devices:

  • Levodopa/Carbidopa pump for infusion in the small intestine
  • Levodopa/Carbidopa pump for infusion under the skin

Britannia Pharmaceuticals

  • Apomorphine pump for infusion under the skin
  • Levodopa/Carbidopa/Entacapone pump for infusion in the small intestine
  • Infusion set for apomorphine pump and levodopa/carbidopa

EVER Pharma

  • Apomorphine pump for infusion under the skin
 
Press "Back" below to return to the previous screen, or click "Next" to find out about MR-Focused Ultrasound.
MR-guided Focused Ultrasound (MRgFUS)
 
 
What is MR-guided Focused Ultrasound?
 
MR-guided Focused Ultrasound (MRgFUS) is an incisionless, one-day procedure with short recovery time for people living with Parkinson’s.
 
It uses ultrasound waves, guided by MRI (Magnetic Resonance Imaging), to precisely treat areas of the brain.
 
The procedure is currently unilateral (treating one side of the body). The patient is awake during the procedure, which lasts for around 2-3 hours, and can normally go back to normal life within a few days after therapy.
 
 
What are the benefits and risks of MR-guided Focused Ultrasound?
 
The benefits of the procedure are reduction of motor symptoms and motor complications and improvement in quality of life.
 
Side effects (such as gait and speech) are common, but most are mild to moderate and progressively resolved.
 
 
Where to find out more about MR-guided Focused Ultrasound
 
The company Insightec is currently the sole company providing MRgFUS for movement disorders.

Watch this story by the BBC featuring Oscar, living with Parkinson’s and treated with MRgFUS : Can technology help reduce Parkinson’s symptoms?
 
 
Press "Back" below to return to the previous screen, or click "Next" to find out more about DATTs.
 
 
MR-guided Focused Ultrasound (MRgFUS)
 
 
What is MR-guided Focused Ultrasound?
 
MR-guided Focused Ultrasound (MRgFUS) is an incisionless, one-day procedure with short recovery time for people living with Parkinson’s.
 
It uses ultrasound waves, guided by MRI (Magnetic Resonance Imaging), to precisely treat areas of the brain.
 
The procedure is currently unilateral (treating one side of the body). The patient is awake during the procedure, which lasts for around 2-3 hours, and can normally go back to normal life within a few days after therapy.
 
 
What are the benefits and risks of MR-guided Focused Ultrasound?
 
The benefits of the procedure are reduction of motor symptoms and motor complications and improvement in quality of life.
 
Side effects (such as gait and speech) are common, but most are mild to moderate and progressively resolved.
 
 
Where to find out more about MR-guided Focused Ultrasound
 
The company Insightec is currently the sole company providing MRgFUS for movement disorders.

Watch this story by the BBC featuring Oscar, living with Parkinson’s and treated with MRgFUS : Can technology help reduce Parkinson’s symptoms?
 
 
Press "Back" below to return to the previous screen, or click "Next" to find out more about DATTs.
 
 
Why are there different types of DATTs?
 
There are different types of DATTs because they all work in slightly different ways, and also because they were developed and went through the research and licensing process at different times.
 
This means there are a number of different versions of some of the DATTs. You can find out about all of this by reading more of this resource.
Why are there different types of DATTs?
 
There are different types of DATTs because they all work in slightly different ways, and also because they were developed and went through the research and licensing process at different times.
 
This means there are a number of different versions of some of the DATTs. You can find out about all of this by reading more of this resource.
Could I use more than one DATT and would I still take my other Parkinson's medication?
 
Potentially yes, however this would need to be decided by you and your clinician.
 
Each DATT comes with its own set of guidelines and recommendations, and it also depends on what treatment combinations will best support you to live as full a life as possible.
Could I use more than one DATT and would I still take my other Parkinson's medication?
 
Potentially yes, however this would need to be decided by you and your clinician.
 
Each DATT comes with its own set of guidelines and recommendations, and it also depends on what treatment combinations will best support you to live as full a life as possible.
Are these treatments available in my country?
 
Unfortunately, not all Parkinson's treatments are available in every country. This is due to each country having its own rules and regulations around healthcare and medical treatment.
 
We are working hard with our industry partners to list where in Europe that each of the different DATTs are available, and we will try to keep that information up to date in this resource.
 
Countries where Deep Brain Stimulation is available

Find a DBS treatment centre

 

Countries where infusion pump treatment is available

Convatec's infusion set is available from the following European countries:

Austria, Belgium, Denmark, Finland, France, Germany, Greece, Italy, Netherlands, Norway, Spain, Sweden, United Kingdom

 

Countries where Focused Ultrasound is available

Insightec Treatment Centres

Are these treatments available in my country?
 
Unfortunately, not all Parkinson's treatments are available in every country. This is due to each country having its own rules and regulations around healthcare and medical treatment.
 
We are working hard with our industry partners to list where in Europe that each of the different DATTs are available, and we will try to keep that information up to date in this resource.
 
Countries where Deep Brain Stimulation is available

Find a DBS treatment centre

 

Countries where infusion pump treatment is available

Convatec's infusion set is available from the following European countries:

Austria, Belgium, Denmark, Finland, France, Germany, Greece, Italy, Netherlands, Norway, Spain, Sweden, United Kingdom

 

Countries where Focused Ultrasound is available

Insightec Treatment Centres

What simple questions can I ask my doctor about Device-Assisted Treatments and Therapies?
 
We've compiled a printable PDF giving some questions that you might find useful in discussions with your healthcare professionals about Device-Assisted Treatments and Therapies.
 
Download the PDF [link TBC]
What simple questions can I ask my doctor about Device-Assisted Treatments and Therapies?
 
We've compiled a printable PDF giving some questions that you might find useful in discussions with your healthcare professionals about Device-Assisted Treatments and Therapies.
 
Download the PDF [link TBC]
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