The rejected MCAT Kidney Transplant Questions
Which type of donor has better outcomes post transplant?
DCD
DBD
Living Donor
Recipient HLA-A is 2,4 and HLA B is 3,-. Donor has HLA-A 3,3 and HLA-B 9, 11. How many mismatches are there?
0
1
2
3
4
5
6
How many phases are there in clincal trials per FDA?
1
2
3
4
5
Which one of these drugs is NOT an induction agent?
Methylprednisolone
Prednisone
Basiliximab
ATG
They are all induction agents
What is PLEX?
Plasma Exchange
Method to detect antibodies in recipient
Platelet Exchange
Machine used to treat delayed graft fuction
Proton beam emitter used to treat Renal Cell Carcinoma
True or False: Higher your EPTS score is, more likely your graft will survive longer
True
False
Select all the following characteristics that are used to calculate KDRI (which KDPI is derived from). Total = 10
Donor Age
Recipient Age
Height
Weight
Previous Transplant
History of Diabetes
Cause of Death
Recipient Ethnicity/Race
Donor Ethnicity/Race
Hepatitis B
Hepatitis C
HIV
DCD Status
Donor Renal Cancer
Hypertension
Donor Serum Creatinine
What is b?
Glomerulus
Bowman's capsule
Afferent Arteriole
Efferent Arteriole
Afferent Venule
Efferent Venule
Collecting Duct
True or False: The higher the KDPI, the greater the risk of graft failure
True
False
A 62y/o female, 3-month post kidney DDRT transplant patient, KDPI 32%, cPRA 5%, 2MM HLA comes in for a routine visit. You noticed her creatinine has jumped from 1.1 to 2.3 since her last visit 2 weeks ago and her dd-cfDNA went from 0.6% to 1.8%. She states slight weight loss of 10lbs since her transplant admission. Her vitals are normal, and mild diarrhea. What test/procedure would you do first to determine her results?
Re-check Creatinine in 2 weeks to see if it goes up further
Check CMV/BK viral results
Send for for-cause biopsy
Re-check her dd-cfDNA in 2 weeks
Perform an Kidney Ultrasound
Perform a stool study
What drug was replaced by tacrolimus for stndard triple immunosuppression therapy??
Sirolimus
Rapamycin
Prednisone
Cyclosporine
Belatacept
What recipient artery is typically anastamosed with the donor renal artery?
Recipient Renal Artery
Femoral Artery
Inferior mesenteric artery
Superior mesenteric artery
External Iliac Artery
Internal Iliac artery
What country first discovered Tacrolimus?
France
US
Canada
Germany
Japan
Which segment is impermeable to water?
Descending limb of loop of Henle
Thin ascending limb of loop of Henle
Collecting Tubules
Proximal Tubule
What is the active vitamin D form the kidney synthesizes?
1,25-dihydroxyvitamin D
25-hydroxyvitamin D
1-hydroxyvitamin D
None of these are correct
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