Bio test
Karyotyping and Cell Division Quiz
Test your knowledge on karyotyping, cell division, and genetic disorders with our comprehensive quiz. Designed for students and biology enthusiasts, this quiz covers essential topics in genetics and cell biology.
- 25 questions to challenge your understanding
- Multiple choice and checkbox formats
- Learn about karyotypes, chromosome structure, and cell cycle phases
What are the indications to perform karyotyping?
Infertility
Familiar clustering of colorectal cancers
Recurrent natural abortions
Occurence of malformations in the offspring of the patient
Diagnosing of viral infections
Mark the correct sequence of phases during mitotis
Meta – pro – ana – telo
Pro – ana – telo – meta
Pro – meta – ana – telo
Pro – meta – telo – ana
What is true about mosaicism? (!!!)
Occurs in somatic cells only
It occurs quite often in healthy cells
Every cell has the same genotype
Different genotypes in one individual
Which of these are examples of balanced translocations? (!!!)
R-banding
C-banding
G-banding
Q-banding
All above
Is it true that (!!!)
Mitosis leads to creation of diploid cells
Meiosis leads to creation of diploid cells
Mitosis take place in germ cells
Mitosis takes place in somatic cells
Which of these are examples of balanced translocations?
47, XX, +21
46, XY, t(9:22)(q34:q11)
46, XY, del(5)(p25)
46, XX, t(10:12)(p12:q21)
69, XXY
A male patient has an invertion in one of his chromosomes, mark the correct
46 XY, ins(7p2)
46 XY, inv(2q1)
46 XX, ins(4q21)
46 XX, inv(9p13)
What process does belong to the telophase?
Cytokinesis of the cell
Formation of a new nuclear envelope
Unwinding of the chromosomes
Disappearance of the spindle
Replication occurs during
Prophase
G1-phase
S-phase
Anaphase
What happens during the G1 phase in the cell cycle?
Transcription
DNA replication
Translation
Chromosomes start condensing
Nuclear envelope disappearing
Mark true sentences
Edward syndrome is 45 X0
Down syndrome is referred as trisomy 21
Turner syndrome is referred as trisomy 18
Klinefelter syndrome is referred as 47, XXY
What can you tell about this karyotype: 46 XY, del(15)(q24;qter)
This can be detected with karyotyping
This patient has an inversion on chromosome 13
This patient is a male
This patient has an insertion on the short arm of chromosome 15
Metacentric chromosome is characterized by
The same length of arms p=q
P arm is longer than q arm (p>q)
Q arm is longer than p arm (q>p)
Is not present in human cells
Unbalanced reciprocal translocation between non-homologous chromosomes
Usually does not lead to disease
Has usually more severe clinical impact on a carrier than a balanced reciprocal translocation
Can be detected by karyotyping performed during S phase
Can be detected by karyotyping performed during interphase
What kind of mutation does lead to Down syndrome?
Robertsonian translocation between chromosomes 14 and 21
Trisomy of 22 chromosome
Polyploidy
Aneuploidy
Chromatin is made up of (!!!)
DNA only
DNA and proteins only
DNA, proteins and small amounts RNA
RNA and small amount of DNA
Karyotyping can be performed on
Sample from fetus biopsy
Frozen tissue sample
Fresh blood
DNA isolated from blood
Formalin fixed paraffin embedded tissue
Tetrads are formed during: (!!!!)
Prophase 1 of meiose
Anaphase of mitosis
Anaphase 1 of meiose
Anaphase 2 of meiose
During which stages of meiosis do tetrads line up at equator? (!!!)
Metaphase 1
Telophase 1
Metaphase 2
Anaphase 2
Anaphase
During which stage of mitosis do the centromeres split? (!!!)
Prophase
Interphase
Anaphase
Telophase
Synthesis phase
What process belongs to telophase?
Cytokinesis of the cell
Formation of new nuclear envelope
Unwinding of the chromosomes
Disappearance of the spindle
Mark the chromosomes that are present in human cells:
Telocentric
Metacentric
Submetacentric
Acrocentric
Replication DNA occurs during:
Prophase
G1 phase
S phase
Anaphase
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