Myasthenia Gravis Quiz
By:Mohamed Mamdouh
What is the primary cause of Myasthenia Gravis?
Viral infection
Genetic factors
Autoimmune response
Environmental toxins
What neurotransmitter is deficient in the neuromuscular junction in Myasthenia Gravis?
Serotonin
Dopamine
Acetylcholine
Norepinephrine
Which muscle group is commonly affected first in Myasthenia Gravis?
Lower extremities
Facial muscles
Upper extremities
Respiratory muscles
What is the hallmark symptom of Myasthenia Gravis?
Muscle weakness that worsens with activity
Muscle spasticity
Loss of coordination
Tremors at rest
Which diagnostic test is often used to confirm Myasthenia Gravis?
MRI
CT scan
Electromyography (EMG)
Blood culture
Which of the following is a pharmacological treatment for Myasthenia Gravis?
Antibiotics
Cholinesterase inhibitors
Beta-blockers
Antifungals
What is the role of thymectomy in the management of Myasthenia Gravis?
It is a first-line treatment
It is performed to relieve symptoms but not cure the disease
It is only done in advanced stages
It has no impact on the condition
Myasthenic crisis is characterized by:
Exacerbation of symptoms leading to respiratory failure
Complete remission of symptoms
Onset of seizures
Increased muscle strength
What is the role of plasmapheresis in the treatment of Myasthenia Gravis?
It acts as an immunosuppressant
It removes circulating antibodies
It enhances acetylcholine release
It stimulates muscle regeneration
What is the role of neostigmine in Myasthenia Gravis management?
Muscle relaxant
Immunosuppressant
Cholinesterase inhibitor
Antibiotic
What is the mechanism of action of corticosteroids in the treatment of Myasthenia Gravis?
Increase acetylcholine release
Suppress the immune system
Block neuromuscular transmission
Enhance muscle strength
What is the role of respiratory function tests in Myasthenia Gravis?
They help in the diagnosis of the condition
They monitor respiratory muscle strength
They measure muscle spasticity
They have no relevance in Myasthenia Gravis
A positive response to the Tensilon test is characterized by:
Worsening of symptoms
Temporary improvement of symptoms
No change in symptoms
Permanent cure
What is the role of immunosuppressive medications in Myasthenia Gravis management?
They enhance the immune response
They suppress the production of acetylcholine
They modulate the immune system to reduce attacks on neuromuscular junctions
They stimulate muscle contraction
What is the recommended treatment for a Myasthenia Gravis crisis with respiratory failure?
Intravenous immunoglobulin (IVIG)
Plasmapheresis
Mechanical ventilation
High-dose corticosteroids
What is the role of edrophonium in the diagnosis of Myasthenia Gravis?
It prolongs muscle weakness
It is used to reverse muscle weakness temporarily
It is a treatment for the condition
It has no diagnostic significance
Which of the following is NOT a common symptom of Myasthenia Gravis?
Hyperactivity
Diplopia
Ptosis
Dysphagia
Which of the following activities is likely to worsen symptoms in a person with Myasthenia Gravis?
Regular exercise
Prolonged rest
Stressful situations
Adequate sleep
Which surgical procedure involves the removal of the thymus and is used in the treatment of Myasthenia Gravis?
Tonsillectomy
Thyroidectomy
Thymectomy
Nephrectomy
What is the main goal of treatment for Myasthenia Gravis?
Reduction of muscle contractility
Prevention of muscle atrophy
Complete cure
Symptom control and improvement in quality of life
Myasthenia gravis occurs when antibodies attack the __________ receptors at the neuromuscular junction leading to ____________.
Metabotropic; muscle weakness
Nicotinic acetylcholine; muscle weakness
Dopaminergic adrenergic; muscle contraction
Nicotinic adrenergic; muscle contraction
You're educating a patient about the pathophysiology of myasthenia gravis. While explaining the involvement of the thymus gland, the patient asks you where the thymus gland is located. You state it is located?
Behind the thyroid gland
Within the adrenal glands
Behind the sternum in between the lungs
anterior to the hypothalamus
A patient with myasthenia gravis will be eating lunch at 12:00 PM It is now 10:00 AM and the patient is scheduled to take Pyridostigmine. At what time should you administer this medication so the patient will have the maximum benefit of this medication?
As soon as possible
1 hour after the patient has eaten (at 1:00 PM)
1 hour before the patient eats (at 11:00AM)
At 12:00 PM right before the patient eats
The neurologist is conducting a Tensilon test (Edrophonium) at the bedside of a patient who is experiencing unexplained muscle weakness, double vision, difficulty breathing, and ptosis. Which findings after the administration of Edrophonium would represent the patient has myasthenia gravis?
The patient experiences worsening of the muscle weakness.
The patient experiences wheezing along with facial flushing
The patient reports a tingling sensation in the eyelids and sudden ringing in the ears
The patient experiences improved muscle strength.
Which patient below is MOST at risk for developing a cholinergic crisis?
A patient with myasthenia gravis is who is not receiving sufficient amounts of their anticholinesterase medication.
A patient with myasthenia gravis who reports not taking the medication Pyridostigmine for 2 weeks.
A patient with myasthenia gravis who is experiencing a respiratory infection and recently had left hip surgery.
A patient with myasthenia gravis who reports taking too much of their anticholinesterase medication.
Which meal option would be the most appropriate for a patient with myasthenia gravis?
Roasted potatoes and cubed steak
Hamburger with baked fries
Soup and mashed potatoes
Fresh veggie tray with sliced cheese cubes
Select all the signs and symptoms below that can present in myasthenia gravis:
Respiratory failure
Increased salivation
Diplopia
Ptosis
Slurred speech
Restlessness
Mask-like appearance of looking sleepy
Difficulty swallowing
You're providing teaching to a group of patients with myasthenia gravis. Which of the following is not a treatment option for this condition?
Plasmapheresis
Cholinesterase medications
Thymectomy
Corticosteroids
You're a home health nurse providing care to a patient with myasthenia gravis. Today you plan on helping the patient with bathing and exercising. When would be the best time to visit the patient to help these tasks?
Mid-afternoon
Morning
Evening
Before bedtime
In which gender is Myasthenia Gravis more commonly diagnosed?
Male
Female
Equal distribution between male and female
More common in children
What is the role of immunoglobulin therapy (IVIG) in the treatment of Myasthenia Gravis?
It promotes the production of antibodies
It replaces the deficient neurotransmitter
It Decrease production of abnormal antibodies
It directly strengthens muscle fibers
What role does pyridostigmine play in the management of Myasthenia Gravis?
It blocks acetylcholine receptors
It enhances acetylcholine levels by inhibiting its breakdown
It is an immunosuppressant
It stimulates muscle growth
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