Immunologia 2023 EP (PUM)

A visually engaging and informative illustration representing immunology concepts, including immune cells, vaccination protocols, and antibody responses, in a scientific and academic style.

Immunology Challenge 2023

Test your knowledge of immunology with our comprehensive quiz designed for students and enthusiasts alike. Dive deep into various topics, from NK cells to autoimmune diseases, and see how well you understand the immune system's nuances.

34 challenging questions
Covering a range of immunology topics
Engage with interactive content

34 Questions8 MinutesCreated by AnalyzingCell45

Choose correct about NK cells:

Cytotoxic cells to cells infected by viruses, cancerous cells and allogenic transplants

Kill with the participation of perforins and granzymes in direct cytotoxic mechanism

Kill with the ADCC mechanism with participation of CD18 receptor

Are cytotoxic cells to extracellular bacteria and parasites

For the recognition of foreign antigen they do not require MHC restriction

Choose correct about prophylactic vaccination:

BCG is a inactive vaccine and it should be given in 2 reminding doses

IPV is a inactive vaccine against polio virus

DTP is a vaccine which includes toxoids

Vaccination against measles, mumps and rubella is performed with a associated vaccine including all three viruses

Vaccination against Haemophilus influenza type B belongs to recommended vaccinnations

Black – neon green picture:

Glomeruli – antiAMB – Goodpasteure'a syndrome

Parietal cells – APCA – Addison-Biermere – syndrome

Hep – 2010 cells – antidsDNA – lupus erythmatosus

No correct answer

Lung alveoli – antiGBM – Goodpasteure'a syndrome

KIdney donor’s antigens
HLA: HLA – A*03, 06; B*07, 56; DRB1*01, 12,
Recepient’s HLA – A*07, 06; B*12, 56; DRB1*03, 12 and positive vPRA:
anti-HLA A1 (5678), A11 (12567), B2 (123), B27 (4256), Dr9 (567), DR17 (3987).

Is the transplant possible in this situation?:

No, because the recipient has positive anti-DSA under 5000 MFI and is disqualified for the cross match

Yes, because the recipient has positive anti-DSA under 5000 MFI and is qualified for the cross match

Yes, because the recipient has positive anti-DSA above 5000 MFI and is qualified for the cross match

No, because the recipient has positive anti-DSA above 5000 MFI and is disqualified for the cross match

Yes, becuase the recipeint has no anti-DSA and in case of negative cross match the transplant is possible

Defensin action mechanism:

Cuts the beta-glycosidic bonds in the cellular wall of bacteria

Digestion of the cellular wall, cause defensins act as hydrolytic enzymes

Bind to the membrane of the pathogen and induce perforation

Bind iron ions, necessary for living of bacteria

Destroying of the bacterial cellular wall

Notrelated kidney donor has HLA:
HLA – A* - 01, 03; B* - 04, 12; DR B1* - 0108
Blood group “A” Rh(+)
HIV(-), HCV(+), HBV(-), CMV(-), SARS-CoV(-)

Choose the most matching donor:

Based on the figure match letters (A-C) to cells/part of cells during the activation of immunological response:

A-lymphocyte Tc, B- APC cell, C- CD28

A-lymphocyte Tc, B- egg cell, C- CD28

A- lymphocyte Th, B- APC- cell, C-CTLA4

A- lymphocyte Th, B- egg cell, C- CD2

A- lymphocyte Th, B- APC-cell, C- CD28

Choose correct accroding the vaccination against tuberculosis:

Vaccination contains live attenuated strain of Mycobacterium tuberculosis

Vaccination contains live attenuated strain of Mycobacterium bovis

Vaccination contains inactive microorganisms

Is done in the first day of life

Is done in the 19th year of life

Choose correct according factors leading to self-tolerance defect:

To esogenous factors we include gender and age

To endogenous factors we include genetic factors

HLA-B27 is a clean allel in patients with myasthenia

Anitgen M5 Streptococcus group A can be a cause of rheumatic fever

Exposition to sun light can be related to characteristic skin lesions in lupus

Choose correct according lymphocytes B:

Characteristic receptor is BCR receptor which is coupled with CD3 molecule

IgM and IgG occur on pristine lymphocytes B

Mature in thymus

Show expression of CD80/CD86

Characteristic differntiation marker is CD15

Choose correct: hypersensitivity type – disease:

Choose correct according phagocytosis:

Phagocytosis is performed by NK cells

To main chemotactic factors we include C5a and IL-8

The main role in oxygen independent killing plays myeloperoxidase

To migration stage of neutrophils to site of inflammation includes: chemotaxis, rolling, activation, tight adhesion, diapedisis

Phagocytosis is more effective in the presence of antibodies

Answer acquired cell is the most important defense mechanism in the case of viral secondary infection, because onlt antibodies are able to eliminate infected cells:

Both answers are wrong

Both answers are wrong, without cause and effect relationship

First answer is wrong, second correct

Both answers are correct with cause and effect relationship

First answer is correct, second false

Choose false:

Protein antigens do not belong the MHC restriction

IFN-y is the main cytokine stimulating formation of IgE

Th2 ist the population of cells regulating acquired humoral response

IL-4 and IL-3 are main cytokines secreted by Th1

Dendritic cells show the expression of MHC I and MHC II

Choose correct:

Antigen HLA are included in autoimmunity and are a diagnostic criteria in every autoimmune disease

Autoantibodies are diagnostic criteria in autoagression disease

Hashimoto disease is a systemic disease

Presence of autoantibodies always evidence a autoimmune disease

Skin, kidneys and joints is a common location of changes in systemic disease

Choose correct according cross-match test (CXM):

Done right before a kidney transplant

Aims if the recipient has antibodies against HLA antigenes occuring in our population

Based on the ADCC reaction

Material from recipient are lymphocytes and from donor serum

Helps in prevention of hyperacute rejection

In the course of progressive systemic sclerosis significant antibodies are:

Choose correct connection between the most important molecules co-stimulating, showing inhibitory action:

Choose correct connection: cell –> test (picture):

Neutrophil – Wright test

Lymphocyte – blastic transformation test

Neutrophil – Rosette test

Neutrophil – spontaneous NBT test

Lymphocyte – Killing test

Which from the innate immunity diseases is counted to deficiencies of antibody deficiency

Choose correct according the figure:

Figure shows the process of classic complement activation and its missing element X is C5 convertase

Figure shows the process of classic compplement activation and its missing element X is C4b2a3a

Figure shows a process of lectin complement activation and its missing element X is C42a3a

Figure shows a process of alternative complement activation and its missing element X is complex attacking membranes

Figure shows a process of classic complement activation and its missing element X is convertase C3

Choose correct about immune reaction:

Graft versus host reaction is the most common complication after vascularized organs transplantation

Humoral response mechanism can be responsible for acute kidney rejection

Cellular cytotoxicity takes part in reactions of acute accelerated rejection

Negative virtual cross-match excludes reaction of acute rejection

Choose correct:

Toll-similar receptors include PAMP molecules

Alternative way of genitive activation is activated by MBL

Mastocytes are activated by genitive components C3a and C5a

C3a and C5a are chemoattractants

Phagocytotic cells do not show chemotaxis

Choose correct according hypersensitivity type I:

An example is atopic reaction, which can occur in every healthy person

To preformed mediators, secreted from mast cell are prostaglandins and PAF

Anafilactoid reaction occurs already at the first contact with antigen

Desensentization is about production of antibodies blocking IgG class, which bind antigen, do not allow crosslinking of antibodies IgE

A significant role in diagnostics play radioimmunological tests RIST and RAST

Choose correct according SLE:

All answers are correct

Immunological complexes are accumulated in kidneys and skin

DsDNA antibodies play a sifnificant role in diagnostics of this disease

Predisposed people are women in age of 30-40 years

Systemic disease is related to type III hyperensitivity

Choose correct:

VDRL test belongs to tests based on precipitation

Precipitation sample reaction is a quality test

Blastic transformation test is a quantitive test

Slide agglutination reaction is a quantitive test

Radial immunodiffusion test is a quantitive test

Choose correct: name of the test – result

ELISA – quantitiy test – positive (previous infection)

WB – quantitiy test – positive (fresh infection)

WB – quality test – positive (previous infection)

IFT – quality test – negative (fresh infection)

WB – quality test – positive (fresh infection)

Which of the following diseases are related to phagocytosis deficiency:

Which of the mechanisms of the immunological response condition immunotolerance in pregnancy:

Modulation of NK cells

Cytotoxicity of NK cells

Activity of 2,3- dioxygenaseindolamine

Presence of fetal DNA in mothers circulation

Activity of lymphocytes Treg

The presence of hemolysis in the final stage of complement fixation test shows:

Absence of wanted antigen

Presence of wanted antigen

Absence of wanted antibodies

Presence of wanted antibodies

Absence of wanted antigenes and antibodies

Unlock and Upgrade

Remove all limits from your Quizzes

Immunologia 2023 EP (PUM)

Immunology Challenge 2023

More Quizzes