Emergency USMLE 3 (216-300)
Emergency Medicine Quiz: USMLE Step 3
Welcome to the Emergency Medicine Quiz designed for those preparing for the USMLE Step 3. This quiz features 24 multiple-choice questions that assess your knowledge in various emergency scenarios.
Test your clinical reasoning and make crucial decisions in urgent medical situations. Get ready to tackle:
- Emergency diagnosis
- Patient management strategies
- Clinical presentations
A 43-year-old woman presents to the ED with a 3-week history of intermittent headache, nausea, and fatigue. She was seen at her private doctor’s office 1 week ago along with her husband and children, who also have similar symptoms. They were diagnosed with a viral syndrome and told to increase their fluid intake. She states that the symptoms began approximately when it started to get cold outside. The symptoms are worse in the morning and improve while she is at work. Her BP is 123/75 mmHg, HR is 83 beats per minute, temperature is 98.9°F, and oxygen saturation is 98% on room air. Physical examination is unremarkable. You suspect her first diagnosis was incorrect. Which of the following is the most appropriate next step to confirm your suspicion?
. Order a mono spot test
. Perform a nasal pharyngeal swab to test for influenza
. Consult psychiatry to evaluate for malingering
. Order a carboxyhemoglobin (COHb) level
. Order a lead level
A 45-year-old previously healthy male is brought to the emergency room because of headaches and confusion for 2 days. He denies any focal weakness or sensory symptoms. He has no significant past medical history and does not use any medications. He does not use tobacco, alcohol or drugs. On physical exam, the patient has a temperature of 37.9°C (100.2°F), a blood pressure of 140/86 mm Hg, a pulse of 96/min, and respirations of 16/min. Mild icterus is present. The patient's oropharynx is clear and his neck is supple and without rigidity. Examination of the patient's chest and abdomen is unremarkable. Neurologic examination reveals no focal deficits. Laboratory studies show: Complete blood count: Hemoglobin 84 g/L, Platelet count 80,000/mm3, Leukocyte count 5,500/mm3. Chemistry panel:Blood urea nitrogen (BUN) 30 mg/dL, Serum creatinine 2.2 mg/dL, Serum calcium 10.0 mg/dL, Blood glucose 98 mg/dL. A peripheral blood smear shows many fragmented red blood cells. The prothrombin time is normal. Which of the following is the most appropriate next step in the management of this patient?
. Hemodialysis
. MRI of the brain
. Electroencephalogram
. Plasma exchange
. Platelet transfusion
A 45-year-old woman is brought to the ER by ambulance after a neighbor found her to be in a somewhat obtunded state with an empty bottle of medication next to her. While en route to the ER she suffered a tonic clonic seizure. Her past medical history is significant for major depression. Her temperature is 38.3°C (100.9°F), blood pressure is 90/70 mmHg, pulse is 120/min, and respirations are 16/min. She is able to respond to painful stimuli. Pupils are 8 mm in size bilaterally. Skin is warm and flushed. Lungs are clear to auscultation. Abdomen is soft and non-tender. Bowel sounds are decreased. There is no neck stiffness. EKG shows QRS duration of 130 msec, a change from her previous EKG a month ago. Which of the following is the most appropriate next step in management?
. Lumbar puncture
Echocardiogram
. Thyroid function tests
. Calcium gluconate
. Sodium bicarbonate
A 45-year-old woman presents to the emergency department (ED) with vomiting and severe right flank pain that radiates to her groin. She has been to the ED twice in the past due to similar episodes of renal colic, and was subsequently discharged on both occasions. She admits to not seeking further medical care because she has no insurance. KUB shows a renal stone. 24-hour urine collection shows a urinary calcium excretion of 350 mg (normal is less than 250 mg in women). Laboratory studies show a serum calcium concentration of 8.9 mg/dL; serum PTH is normal. An x-ray film of the chest shows no abnormalities. Further investigations fail to reveal the cause of her hypercalciuria. Apart from advising her to increase her fluid intake, which of the following interventions will benefit this patient?
. Restriction of calcium in her diet
. Thiazide diuretics
. Low dose furosemide
. High sodium intake
. Potassium citrate
A 46-year-old male is admitted to the hospital because of right hand cellulitis. He has a history of intravenous drug use, hepatitis C infection and septic arthritis of the knee. He smokes one pack of cigarettes and drinks one pint of vodka daily. He is started on vancomycin. On the following day, the swelling and redness of his arm decreases. However, he complains of bugs crawling on his skin. His temperature is 38.3°C (100.9°F), blood pressure is 160/90 mmHg, pulse is 110/min, and respirations are 18/min. Examination shows mild hand tremors and diaphoresis. Which of the following is the most appropriate next step in management?
. Start chlordiazepoxide
. Give haloperidol
. Start propranolol
. Stop vancomycin
. Start methadone
A 48-year-old man presents to the emergency department complaining of crushing substernal chest pain. He is diaphoretic, anxious, and dyspneic. His pulse is 110/min, blood pressure is 175/112 mmHg, respiratory rate is 30/min, and oxygen saturation is 94%. Aspirin, oxygen, sublingual nitroglycerin, and morphine are given, but they do not relieve his pain. ECG shows ST-segment elevation in leads V2 to V4. The duration of symptoms is now approximately 30 minutes. What is the most appropriate treatment for this patient at this time?
Calcium channel blocker
Intravenous angiotensin-converting enzyme inhibitor
Intravenous β-blocker
Magnesium sulfate
Tissue plasminogen activator
A 49-year-old man presents to the clinic for a health maintenance visit. He has no complaints, but he requests a prescription for his “pressure pills,” as he lost his original prescription. On physical examination his blood pressure is 220/130 mmHg. Physical examination is otherwise within normal limits. Laboratory tests show: Na+: 142 mEq/L, K+: 3.8 mEq/L, Cl−: 105 mEq/L, Carbon dioxide: 25 mEq/L, Blood urea nitrogen: 20 mg/dL, Creatinine: 1.0 mg/dL, Glucose: 133 mg/dL. Urinalysis is within normal limits, and his ECG is normal. Which of the following is the most effective management?
Administer intravenous nitroprusside for management of hypertensive emergency
Administer intravenous nitroprusside for management of hypertensive urgency
Administer oral furosemide for management of hypertensive emergency
Administer oral metoprolol for management of hypertensive urgency
Administer sublingual nifedipine for management of hypertensive emergency
A 5-year-old boy is brought into the ER immediately after an unfortunate altercation with a neighbor’s immunized Chihuahua that occurred while the child was attempting to dress the dog as a superhero. The fully immunized child has a small, irregular, superficial laceration on his right forearm that has stopped bleeding. His neuromuscular examination is completely normal, and his perfusion is intact. Management should include which of the following?
Irrigation and antimicrobial prophylaxis
Tetanus booster immunization and tetanus toxoid in the wound
Copious irrigation
Destruction of the dog and examination of brain tissue for rabies
Primary rabies vaccination for the child
A 51-year-old man is brought to the emergency department (ED) by emergency medical services (EMS) with a blood pressure (BP) of 90/60 mm Hg, heart rate (HR) of 110 beats per minute, respiratory rate (RR) of 18 breaths per minute, and oxygen saturation of 97% on room air. The patient tells you that he has a history of bleeding ulcers. On examination, his abdomen is tender in the epigastric area. He is guaiac positive, with black stool. He has a bout of hematemesis and you notice that his BP is now 80/50 mm Hg, HR is 114 beats per minute, as he is slowly starting to drift off. Which of the following is the most appropriate next step in therapy?
Assess airway, establish two large-bore intravenous (IV) lines, cross-match for two units of blood, administer 1 to 2 L of normal saline, and schedule an emergent endoscopy
. Assess airway, establish two large-bore IVs, cross-match for 2 units of blood, and administer a proton pump inhibitor
. Place two large-bore IVs, cross-match for 2 units of blood, administer 1 to 2 L of normal saline, and schedule an emergent endoscopy
Intubate the patient, establish two large-bore IVs, cross-match for 2 units of blood, administer 1 to 2 L of normal saline, and schedule an emergent endoscopy
. Intubate the patient, establish two large-bore IVs, cross-match for 2 units of blood, and administer a proton pump inhibitor
A 54-year-old Caucasian woman presents to your office with fatigue. She also reports dizziness and palpitations after moderate physical activity. Additionally, her feet feel "numb" and are less sensitive to cold than they used to be. She has no significant past medical history. Physical examination reveals pale conjunctivae and a shiny tongue. Ankle reflex is decreased bilaterally. Laboratory findings include: Hemoglobin 7.6 mg/dL, MCV 110 fL, MCHC 36 g/dL, WBC count 3,900/mm3, Platelet count 150,000/mm3. This patient should be monitored for which of the following long-term complications?
. Acute myelogenous leukemia
. Hodgkin's disease
. Celiac sprue
. Gastric cancer
. Liver cirrhosis
A 54-year-old man is brought to the ER because of an episode of coffee ground emesis and lightheadedness. He has a history of intravenous drug use, hepatitis C infection, and alcohol use. He says he has not had an alcoholic drink for about three days. He has been noncompliant with medications and follow-ups. He takes no medications. His temperature is 36.7°C (98°F), pulse is 110/min, respirations are 16/min, and blood pressure is 90/60 mmHg. Scleral icterus is present. Examination shows coffee ground material in the oropharynx. His lungs are clear. His abdomen is distended and a fluid wave is present. He is slightly tender to palpation in the epigastrium. Laboratory studies show: Complete blood count:Leukocyte count 9,500/mm3, Hemoglobin 10.0 g/L, Platelets 120,000/mm3. Chemistry panel:Serum sodium 140 mEq/L, Serum potassium 3.5 mEq/L, Bicarbonate 27 mEq/L, Blood urea nitrogen (BUN) 34 mg/dL, Serum creatinine 0.8 mg/dL. Coagulation studies :Prothrombin time 27 sec, Partial thromboplastin time 42 sec. Which of the following is the most appropriate next step in the management of this patient?
. Whole blood transfusion
. Fresh frozen plasma infusion
Hemodialysis
. Pooled platelet transfusion
. Plasmapheresis
A 55-year-old man presents to the ED with fever, drooling, trismus, and a swollen neck. He reports a foul taste in his mouth caused by a tooth extraction 2 days ago. On physical examination, the patient appears anxious. He has bilateral submandibular swelling and elevation and protrusion of the tongue. He appears “bull-necked” with tense and markedly tender edema and brawny induration of the upper neck, and he is tender over the lower second and third molars. There is no cervical lymphadenopathy. These lungs are clear to auscultation with good air movement. His vital signs are HR 105 beats per minute, BP 140/85 mmHg, RR 26 breaths per minute, and temperature 102°F. Which of the following is the most appropriate next step in management?
. Obtain a sample for culture, administer a dose of IV antibiotics, and obtain a soft tissue radiograph of the neck
. Obtain a sample for culture, perform a broad incision and drainage at bedside, and administer a dose of IV antibiotics
. Administer a dose of IV antibiotics and obtain a CT scan of the soft tissues of the neck
. Administer a dose of IV antibiotics, obtain a CT scan of the soft tissues of the neck, and obtain an emergent ENT consult
. Secure his airway, administer a dose of IV antibiotics, and obtain an emergent ENT (ear, nose, and throat) consult
A 56-year-old man presents to the emergency department with dyspnea. He describes waking up during the night with difficulty breathing and chest pain that kept him from falling back to sleep. He has never had these symptoms before. His past medical history is significant for long-standing hypertension and non-compliance with his antihypertensive therapy. He has smoked a pack of cigarettes per day for the past 30 years. On physical examination, his blood pressure is 170/100 mmHg and his heart rate is 120/min and regular. Lung auscultation reveals bibasilar rales and scattered wheezes. Which of the following is most likely to relieve this patient's dyspnea?
Metoprolol
Hydralazine
Nitroglycerin
Dopamine
Amiodarone
A 57-year-old man complains of chest palpitations and light-headedness for the past hour. Five years ago he underwent a cardiac catheterization with coronary artery stent placement. He smokes half a pack of cigarettes daily and drinks a glass of wine at dinner. His HR is 140 beats per minute, BP is 115/70 mmHg, and oxygen saturation is 99% on room air. An ECG reveals a wide complex tachycardia at a rate of 140 that is regular in rhythm. An ECG from 6 months ago shows a sinus rhythm at a rate of 80. Which of the following is the most appropriate medication to treat this dysrhythmia?
Digoxin
Amiodarone
Diltiazem
Adenosine
Bretylium
A 59-year-old male presents to the ER with sudden onset severe chest pain associated with vomiting and diaphoresis. The pain radiates to the left shoulder and is not relieved by sublingual nitroglycerine. His past medical history is significant for diabetes mellitus for seven years and hypercholesterolemia for six years. His medications include metformin, glipizide and simvastatin. On physical examination, his blood pressure is 150/98 mmHg and pulse is 86/min. An EKG obtained in the ER shows ST segment elevations in leads aVL and I. Cardiac troponin and CK-MB are elevated. Which of the following medications should be avoided in this patient at this time?
Heparin
Captopril
Nifedipine
Metoprolol
Aspirin
A 59-year-old man with a history of myocardial infarction 2 years ago undergoes an uneventful aortobifemoral bypass graft for aortoiliac occlusive disease. Six hours later he develops ST segment depression, and a 12-lead electrocardiogram (ECG) shows anterolateral ischemia. His hemodynamic parameters are as follows: systemic BP 70/40 mm Hg, pulse 100 beats per minute, CVP 18 mm Hg, PCWP 25 mm Hg, cardiac output 1.5 L/min, and systemic vascular resistance 1000 (dynes)/cm5. Which of the following is the single best pharmacologic intervention for this patient?
. Sublingual nitroglycerin
. Intravenous nitroglycerin
. A short-acting β-blocker
. Sodium nitroprusside
Dobutamine
A 59-year-old woman with renal cell carcinoma presents to the emergency department with severe right upper quadrant (RUQ) pain. She is afebrile, acutely tender in the RUQ, and has shifting dullness and a palpable liver edge. Murphy’s sign is negative. Laboratory studies show: Na+: 138 mEq/L, K+: 3.6 mEq/L, Glucose: 80 mg/dL. Aspartate aminotransferase: 50 U/L Alanine aminotransferase: 43 U/L Alkaline phosphatase: 138 U/L Total protein: 6.4 g/dL, Albumin: 3.8 g/dL, Total bilirubin: 1.1 mg/dL. Imaging demonstrates a spider web of collateral veins in the liver. Although extensive measures are taken, the patient dies 6 hours after arriving. Which of the following was the most likely initial treatment?
A 59-year-old woman with renal cell carcinoma presents to the emergency department with severe right upper quadrant (RUQ) pain. She is afebrile, acutely tender in the RUQ, and has shifting dullness and a palpable liver edge. Murphy’s sign is negative. Laboratory studies show: Na+: 138 mEq/L, K+: 3.6 mEq/L, Glucose: 80 mg/dL. Aspartate aminotransferase: 50 U/L Alanine aminotransferase: 43 U/L Alkaline phosphatase: 138 U/L Total protein: 6.4 g/dL, Albumin: 3.8 g/dL, Total bilirubin: 1.1 mg/dL. Imaging demonstrates a spider web of collateral veins in the liver. Although extensive measures are taken, the patient dies 6 hours after arriving. Which of the following was the most likely initial treatment?
Cholecystectomy
Endoscopic retrograde cholangiopancreatography with dilation of the common bile duct
Exploratory laparotomy
Tissue plasminogen activator followed by anticoagulation
A 6-month-old boy presents to the Emergency Department with a three-day history of cough, congestion and low grade fever. The mother states that the baby has not been feeding well and has used only two diapers over the past 24 hours. Physical examination reveals a pale infant with a temperature of 37.8 C (100.1 F), pulse of 170/min, respirations of 60/min and oxygen saturation of 88% on room air. The patient exhibits nasal flaring, subcostal and intercostal retractions. Lung examination reveals diffuse wheezing. Cardiac examination reveals a regular but tachycardic rhythm with no murmur. Central capillary refill is four seconds. The remainder of the examination is normal. Which of the following is the most appropriate initial step in management?
A 6-month-old boy presents to the Emergency Department with a three-day history of cough, congestion and low grade fever. The mother states that the baby has not been feeding well and has used only two diapers over the past 24 hours. Physical examination reveals a pale infant with a temperature of 37.8 C (100.1 F), pulse of 170/min, respirations of 60/min and oxygen saturation of 88% on room air. The patient exhibits nasal flaring, subcostal and intercostal retractions. Lung examination reveals diffuse wheezing. Cardiac examination reveals a regular but tachycardic rhythm with no murmur. Central capillary refill is four seconds. The remainder of the examination is normal. Which of the following is the most appropriate initial step in management?
. Albuterol nebulizer treatment
. Bolus of intravenous fluids
. Oxygen therapy
. Oxygen therapy
A 60-year-old male is found lying down on the street by police one winter morning. He has been taking ibuprofen for headaches, fluphenazine for his schizophrenia and amitriptyline for chronic painful neuropathy secondary to post-herpetic neuralgia. He is also receiving cephalexin for cellulitis of the right lower leg. His temperature is 34°C (90°F), blood pressure is 80/50 mmHg, pulse is 88/min, and respirations are 12/min. Which of the following medications most likely have contributed to the development of hypothermia in this patient?
Ibuprofen
Ibuprofen
Cephalexin
Fluphenazine
Glucagon
A 60-year-old man comes to the emergency department with shortness of breath and a left-sided dull chest pain. He has had a low-grade fever for the past 3 days. He was treated recently for pneumonia with antibiotics, but says that he never quite returned to baseline. He has no other medical issues and has no allergies. He denies alcohol abuse or drug use. His temperature is 37.8 C (100.0 F), blood pressure is 120/80 mm Hg, and pulse is 70/min. Examination reveals decreased breath sounds on the left and deceased tactile fremitus. Chest x-ray is consistent with a large left-sided pleural effusion greater than 15 mm. A thoracentesis reveals turbid fluid with a white blood cell count of 70,000, red blood cell count of 20,000, LDH of 500 IU/L, and serum LDH of 600 IU/L (normal 50-150 IU/L). A repeat chest x-ray reveals pneumonia in the right upper lobe. Gram stain of the fluid obtained reveals multiple gram-positive diplococci. Pleural fluid pH is 7.1. Which of the following is the most appropriate initial management?
. Antibiotic coverage and observation
. Chest tube insertion
Diuresis
. Pleural biopsy
Pleurodesis
A 61-year-old man with a history of depression and hypertension is brought to the ED by EMS for altered mental status. The patient’s wife states that he stopped taking his fluoxetine 1 month ago and now only takes metoprolol for his hypertension. The patient’s BP is 75/40 mmHg, HR is 39 beats per minute, RR is 14 breaths per minute, oxygen saturation is 99% on 100% oxygen, and fingerstick glucose is 61 mg/dL. The patient is awake and moaning, responding only to deep stimuli. His extremities are cool to the touch. You suspect an overdose of metoprolol. You endotracheally intubate the patient for airway control. Which of the following is the most appropriate next step in management?
. Normal saline bolus, administer atropine, administer 1-g calcium gluconate bolus, then insert a transvenous cardiac pacer
. Put the patient on pacer pads, then administer norepinephrine drip
. Cardioversion with 200 J, then administer atropine
. Normal saline bolus, atropine, norepinephrine
. Normal saline bolus, atropine, glucagon
A 61-year-old woman with a history of congestive heart failure (CHF) is at a family picnic when she starts complaining of shortness of breath. Her daughter brings her to the ED where she is found to have an oxygen saturation of 85% on room air with rales halfway up both of her lung fields. Her BP is 185/90 mmHg and pulse rate is 101 beats per minute. On examination, her jugular venous pressure (JVP) is 6 cm above the sternal angle. There is lower extremity pitting edema. Which of the following is the most appropriate first-line medication to lower cardiac preload?
Metoprolol
Morphine sulfate
Nitroprusside
Nitroglycerin
Oxygen
A 62-year-old Caucasian female complains of frequent headaches, fatigue and recent weight loss. Her shoulder muscles feel stiff in the morning. Her ESR is 85 mm/hr. Which of the following will be the most likely complication of this patient's condition?
. Chronic lymphocytic leukemia
. Hypothyroidism
. Aortic aneurysm
. Ulcerative colitis
. Membranous glomerulonephritis
A 62-year-old man presents to the ED with gradual dyspnea over the last few weeks. He reports that he is a daily smoker and has not seen a physician in years. Upon physical examination, there are decreased breath sounds on the right as compared to the left. A chest radiograph indicates blunting of the right costophrenic angle with a fluid line. A thoracentesis is performed. Given this patient’s history, which of the following most likely describes his effusion?
. Transudative effusion
. Exudative effusion
. Transudative and exudative effusion
. Lactate dehydrogenase < 200 units
. Fluid-to-blood protein ratio < 0.5
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