Molecular biology
Molecular Biology Mastery Quiz
Test your knowledge of molecular biology with this engaging quiz designed for students and enthusiasts alike. Explore key concepts, from the structure of nucleotides to the intricacies of enzyme fun
- Learn about amino acids and their roles in histones.
- Discover what makes DNA negatively charged.
- Understand the importance of various enzymes in purine and pyrimidine synthesis.
Aminoacids that make histones positively charged
Lysine + Arginine
Glutamine + Aspartate
Lysine + Aspartate
Arginine + Glutamate
What makes DNA negative?
The sugar
The phosphate group
The base
The nucleotide
A nucleotide includes:
Nitrogenous base only
Nitrogenous base + phosphate
Nitrogenous base + sugar
Nitrogenous base + sugar + phosphate
Deamination of cytosine gives:
Uracil
Adenine
Guanine
Cytosine
The followings are pared up correctly
A-G
G-C
C-T
A-T
The followings are purines:
Adenine and Thymine
Adenine and Guanine
Guanine and Cytosine
Adenine and Uracil
What gives the sugar and the phosphate for pyrimidine and purine synthesis:
PRPP
PPRP
HGPRT
CPS II
Gives the nitrogen to purine synthesis:
Glycine and glutamine
Glutamine and Aspartate
Glycine and aspartate
THF and CO2
Needed for the novo synthesis of pyrimidines (best answer)
Aspartate and carbamoyl phosphate
Aspartate and CPS II
Aspartate and CO2
Aspartate and Glycine
Hyperuricemia, intellectual disability, self mutilation and aggression, are all characteristics of a deficiency in:
HGPRT
Adenosine deaminase
Orotic acid
CPS II
A deficiency in adenosine deaminase produces:
LEsch-Nyhan
SCID
CVID
Orotic aciduria
CPS II is located in the:
Plasma membrane
Cytosol
Mitochondria
Ribosomes
Rate limiting enzyme for pyrimidine synthesis:
Carbamoyl phosphate synthetase I
Carbamoyl phosphate synthetase II
PRPP
HGPRT
Drug that inhibits ribonucleotide reductase, used for the treatment of Sickle cell disease
5-FU
Metothrexate
Hydroxyurea
Mycophenolate
Drug that inhibits dihydrofolate reductase, lowering dTMP
Pyrimethamine
5-FU
Mycophenolate
Hydroxyurea
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