The Chromosomal Basis of Inheritance
The Chromosomal Basis of Inheritance Quiz
Test your knowledge on the chromosomal basis of inheritance with this informative quiz! Dive into topics ranging from X-linked traits to genetic recombination and discover how much you truly know about genetics.
This quiz includes:
- 20 multiple-choice questions
- Explore various concepts such as linkage maps and genomic imprinting
- Great for learners, teachers, and enthusiasts alike
Most calico cats are female because
A. The males die during embryonic development.
B. the Y chromosome has a gene blocking orange coloration.
C. Only females have Barr bodies.
D. Multiple crossovers on the Y chromosome prevent orange pigment production.
E. A male inherits only one of the two X-linked genes controlling hair color.
A recessive allele on the X chromosome is responsible for red-green color blindness in humans. A woman with normal vision whose father is color-blind marries a colorblind male. What is the probability that a son of this couple will be colorblind?
A. 0
B. 1/4
C. 1/2
D. 3/4
E. 1
Which of the following is true regarding linkage maps? They
A. Always have a total of 100 map units.
B. Can be used to pinpoint the precise physical position of a gene on a chromosome.
C. Reflect the frequency of crossing over between X and Y chromosomes.
D. Require preparation of karyotypes.
E. Are a genetic map based on recombination frequencies.
Which of the following statements is true regarding genomic imprinting?
A. All the choices are correct.
B. It may explain the transmission of Duchenne muscular dystrophy.
C. It is greatest in females because of the larger maternal contribution of cytoplasm.
D. It involves an irreversible alteration in the DNA sequence of imprinted genes.
E. It explains cases in which the gender of the parent from whom an allele is inherited affects the expression of that allele.
One possible result of chromosomal breakage is for a fragment to join a nonhomologous chromosome. This is called a (an)
A. translocation.
B. inversion.
C. duplication.
D. disjunction.
E. deletion.
If a pair of homologous chromosomes fails to separate during anaphase of meiosis I, what will the chromosome number of the four resulting gametes with respect to the normal haploid number (n)?
A. n + 1; n - 1; n - 1; n - 1
B. n + 1; n + 1; n - 1; n - 1
C. n + 1; n - 1; n; n
D. n - 1; n - 1; n; n
E. n + 1; n + 1; n; n
What does a frequency of recombination of 50% indicate?
A. The two genes likely are located on different chromosomes or far apart on the same chromosome.
B. Independent assortment is hindered.
C. Abnormal meiosis has occurred.
D. All of the offspring have combinations of traits that match one of the two parents.
E. The genes are located on sex chromosomes.
What do all human males inherit from their mother?
A. an X chromosome
B. the SRY gene
C. mitochondrial DNA
D. mitochondrial DNA and an X chromosome
E. mitochondrial DNA, an X chromosome, and the SRY gene
The recombination frequency between gene A and gene B is 8.4%, the recombination frequency between gene A and gene C is 6.8%, and the recombination frequency between gene B and gene C is 15.2%. Which is the correct arrangement of these genes?
A. ABC
B. CAB
C. BCA
D. ACB
E. CBA
A human individual is phenotypically female, but her interphase somatic nuclei do not show the presence of Barr bodies. Which of the following statements concerning her is probably true?
A. She has Klinefelter syndrome.
B. She has Turner syndrome.
C. She has the normal number of sex chromosomes.
D. She has an extra X chromosome.
E. She has two Y chromosomes.
Hypophosphatemia (vitamin D-resistant rickets) is inherited as an X-linked dominant disorder. An unaffected woman mates with a male with hypophosphatemia. What is the expected phenotypic ratio of their offspring?
A. 1 normal daughter: 1 daughter with hypophosphatemia
B. 1 normal daughter: 1 son with hypophosphatemia
C. 1 daughter with hypophosphatemia: 1 normal son
D. 3 normal daughters: 1 son with hypophosphatemia
E. 2 normal daughters: 1 normal son: 1 son with hypophosphatemia
What is the mechanism for the production of genetic recombinants?
A. nondisjunction
B. Deletions and duplications during meiosis
C. X inactivation
D. Methylation of cytosine
E. Crossing over and independent assortment
The frequency of crossing over between any two linked genes is
A. Determined by their relative dominance.
B. The same as if they were not linked.
C. Higher if they are recessive.
D. Proportional to the distance between them.
E. Different between males and females.
When Thomas Hunt Morgan crossed his red-eyed F1 generation flies to each other, the F2 generation included both red- and white-eyed flies. Remarkably, all the white-eyed flies were male. What was the explanation for this result?
A. Other female-specific factors influence eye color in flies.
B. The involved gene was on the X chromosome.
C. The involved gene was on an autosome.
D. The involved gene was on the Y chromosome.
E. Other male-specific factors influence eye color in flies.
SRY is
A. An autosomal gene that is required for the expression of genes on the X chromosome.
B. An autosomal gene that is required for the expression of genes on the Y chromosome.
C. Required for development, and males or females lacking the gene do not survive past early childhood.
D. A gene present on the Y chromosome that triggers male development.
E. A gene present on the X chromosome that triggers female development.
Males are more often affected by sex-linked traits that females because
A. X chromosomes in males generally have more mutations that X chromosomes in females.
B. Mutations on the Y chromosome often exacerbate the effects of X-linked mutations.
C. Male hormones such as testosterone often exacerbate the effects of mutations on the X chromosome.
D. Males are hemizygous for the X chromosome.
E. Female hormones such as estrogen often compensate for the effects of mutations on the X.
If a human interphase nucleus of a person contain 3 Barr bodies, it can be assumed that the person
A. has Down syndrome.
B. Is a male.
C. Has four X chromosomes.
D. has Turner syndrome.
E. has 3 X chromosomes.
A map of a chromosome that includes the positions of genes relative to visible chromosomal features, such as stained bands, is called a
A. Cytogenetic map.
B. Physical map.
C. Linkage map.
D. Recombination map.
E. Banded map.
If nondisjunction occurs in meiosis II during gametogenesis, what will be the result at the completion of meiosis?
A. Two gametes will be n + 1, and two will be n - 1.
B. Two of the four gametes will be haploid, and two will be diploid.
C. All the gametes will be diploid.
D. There will be three extra gametes.
E. One gamete will be n + 1, one will be n - 1, and two will be n.
A man who carries an X-linked allele will pass it on to
A. All of his sons.
B. All of his children.
C. All of his daughters.
D. Half of his sons.
E. Half of his daughters.
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