Part 43 (138QCM)
Clinical Diagnosis Challenge
Test your medical knowledge and diagnostic skills with this comprehensive quiz featuring 138 multiple-choice questions. Each question is designed to challenge you and reinforce your understanding of various clinical scenarios, making it an excellent tool for healthcare professionals and students alike.
Highlights of the quiz include:
- Wide range of clinical scenarios
- Detailed explanations provided after each question
- Suitable for both self-assessment and group learning
A 25-year-old previously healthy man is scheduled for elective inguinal hernia repair under general anesthesia. After induction of anesthesia and initial inguinal incision, the patient develops tachycardia, muscle rigidity, fever of 38.5°C, and elevated end-tidal carbon dioxide. Which of the following is the most likely diagnosis?
Malignant hyperthermia
Pneumonia
Atelectasis
Urinary tract infection
Myocardial infarction
A 55-year-old man presents to the emergency department with left lower quadrant abdominal pain. The pain has been present for 1 week, but has increased in intensity over the last 2 days associated with nausea, constipation, and dysuria. Past history is unremarkable. Examination reveals a temperature of 101°F, pulse rate of 95/min, BP of 130/70 mmHg, and normal heart and lung examinations. Abdominal examination reveals fullness and marked tenderness in the left lower quadrant, with voluntary guarding and decreased bowel sounds. Laboratory tests reveal a WBC count of 18,000 with a left shift and 20–50 WBCs in the urinalysis. A CT scan of the abdomen reveals a thickened sigmoid colon with pericolonic inflammation. He is admitted to the hospital for treatment. Which of the following is the most likely diagnosis?
Diverticulitis
Pseudomembranous colitis
colon cancer with contained perforation
Ischemic colitis
Pyelonephritis
A 56-year-old woman has been treated for 3 years for wheezing on exertion, which was diagnosed as asthma. Chest radiograph, shown here, reveals a midline mass compressing the trachea. Which of the following is the most likely diagnosis?
Goiter
Lymphoma
Neurogenic tumor
Lung carcinoma
Pericardial cyst
A 62-year-old woman presents to the physician’s office with complaints of constipation. She has had constipation for the last 6 months, which has worsened over the last month, associated with mild bloating. She noted that her stool has become “pencil thin” in the last month, with occasional blood, but she continues to have bowel movements daily. Past history is unremarkable. Examination reveals normal vital signs and heart and lung examination. Abdominal examination reveals mild fullness, especially in the lower quadrants. Rectal examination shows no rectal masses, but the stool is hematest positive. A barium xray is obtained, and one view is shown in Figure 6-11. Which of the following is the most likely diagnosis?
Untitled
Rectal carcinoma
Diverticulitis with colovesical fistula
Ischemia with stricture
Sigmoid volvulus
Crohn’s disease
A 25-year-old man was admitted to the ICU with severe head injury with a basal skull fracture. Eighteen hours after the injury, he developed polyuria. Urine osmolality was 150 mOsm/Land serum osmolality was 350 mOsm/L. IV fluids were stopped, and 1 hour later urine output and urine osmolality remained unchanged. Five units of vasopressin were administered intravenously, and urine osmolality increased to 300mOsm/L. Select the most likely diagnosis of the patients with polyuria?
Central diabetes insipidus (DI)
Nephrogenic DI
Water intoxication
Solute overload
Diabetes mellitus
A 70-year-old man was admitted to the ICU with severe pancreatitis. During his ICU course, he underwent several CT scans with IV contrast and was also treated with an aminoglycoside for a urinary tract infection. The patient required a prolonged course of TPN, and developed Candida sepsis treated with amphotericin. He subsequently developed polyuria with urine osmolality of 250mOsm/L and serum osmolality of 350 mOsm/L. After receiving 5 units of vasopressin intravenously, there is no change in urine osmolality or urine output. Select the most likely diagnosis of the patients with polyuria?
Nephrogenic DI
Central diabetes insipidus (DI)
Water intoxication
Solute overload
Diabetes mellitus
A 42-year-old man describes intermittent episodes of severe, crushing chest pain that extends to the back and the jaw and last anywhere from a few seconds to several minutes. Many times the pain is accompanied by dysphagia and triggered by the ingestion of very cold or very hot liquids. However, sometimes the pain occurs for no apparent reason. There is no history of regurgitation, and, although the problem has been present for many years, there has been no progression of the symptoms. Repeated ECGs and cardiac enzymes have always been negative. Barium swallow shows an area of "corkscrew" appearance. Manometry shows that about one half of wet swallows produce repetitive simultaneous esophageal contractions of the esophageal body, and that the lower esophageal sphincter has normal pressures and exhibits normal relaxation. Which of the following is the most likely diagnosis?
Diffuse esophageal spasm
Achalasia of the esophagus
Cancer of the lower esophagus
Nutcracker esophagus
Zenker's diverticulum
A 29-year-old man presents to the ER with persistent vomiting and abdominal pain for the last 24 hours. The pain is crampy, diffuse, and has been getting worse. He had a normal bowel movement two days ago and denies diarrhea. The emesis appears green without blood or coffee grounds. He has not eaten since the onset of the pain due to nausea. On exam, his temperature is 36.8° C (98.2° F}, pulse is 91/min, and blood pressure is 116/75 mmHg while sitting and 94/65 mmHg while standing. His abdomen is distended with hyperactive bowel sounds. Percussion reveals tympany and he is diffusely tender to palpation. There is no rebound tenderness or guarding. Laboratory studies reveal:WBC count 9,600/mm3Hematocrit 45%Sodium 147 mEq/LPotassium 3.1 mEq/LCreatinine 1.0 mg/dLAST 20 U/LALT 12 U/LBilirubin 0.8 mg/dLWhich of the following historical findings would you most expect in this patient?
Appendectomy six months ago
High alcohol consumption
Occasional black or tarry stool
Fatty food intolerance
Recent weight loss
A 63-year-old obese female undergoes an elective cholecystectomy after two episodes of acute calculous cholecystitis. Three days after surgery, her blood pressure is 150/100 mmHg, her heart rate is 90/min, and her arterial oxygen saturation is 91 % on room air. She is afebrile. Which of the following would most likely increase her functional residual lung capacity?
Elevation of the head of the bed
Inhaled albuterol
Sequential compression devices to her lower extremities .
Decreasing the dose of her postoperative opioids
Postoperative benzodiazepines
A 62-year-old woman had an abdominal hysterectomy and salpingo-oophorectomy 3 days ago. She had an indwelling bladder catheter during the procedure, which was removed in the recovery room. She has been voiding at will since then. She also had compression pneumatic stockings on both lower extremities during the operation. She began ambulation on the 1st postoperative day, and has been as active as possible under the circumstances, including faithful adherence to a prescribed program of incentive spirometry. On the evening of the 3rd postoperative day, she spikes a fever, with a temperature to 39.4C (103F). Which of the following is the most likely source of the fever?
Urinary tract infection
Atelectasis
Deep thrombophlebitis
Intra-abdominal abscess
Wound infection
A 44-year-old male is found unresponsive and hypotensive at the scene of a high-speed motor vehicle accident. He is intubated and immediately rushed to the emergency department. The passenger in his car is pronounced dead at the scene. Physical examination in the ED shows large bruises over the entire chest wall and collapsed neck veins bilaterally. Lung exam reveals decreased breath sounds on the left side. Chest x-ray shows a large left hemothorax and a widened, rightward deviating mediastinum. The most likely diagnosis is?
Aortic injury
Esophageal rupture
Myocardial rupture
Myocardial contusion
Diaphragm rupture
An 85-year-old male is placed on mechanical ventilation after a complicated elective hernia repair. After five days of endotracheal intubation with mechanical ventilation, the ratio of the rate of carbon dioxide produced to the rate of oxygen uptake is 1.05. What is the best explanation for these findings?
Carbohydrate excess in the diet
Sepsis
High-protein tube feeding
High inspired oxygen fraction
Pulmonary atelectasis
A 75-year-old woman is admitted to the hospital from a nursing home for abdominal pain and pneumonia. She was noted to be short of breath with increasing cough for 2 days before admission. Treatment, consisting of supplemental oxygen, IV antibiotics, and pulmonary toilet, is instituted, with improvement within 2 days. On the third hospital day, her abdominal pain worsens. Examination reveals a mildly distended abdomen with bowel sounds but no signs of peritonitis. Remainder of examination reveals a tender bulge in the medial left thigh below the inguinal ligament. Gentle pressure causes more pain but does not change the size or shape of the bulge. Abdominal films show a nonspecific bowel gas pattern. Laboratory analysis shows a WBC of 13,000, decreased from 18,000 at the time of admission. Which of the following is the most likely diagnosis?
Incarcerated femoral hernia
Incarcerated indirect inguinal hernia
Incarcerated direct inguinal hernia
Lymph node with abscess
Femoral artery aneurysm
A 66-year-old woman picks up a bag of groceries out of the supermarket cart to place it in the trunk of her car. As she does so, she feels sharp, sudden pain in the middle of her arm, and her humerus suddenly breaks. She arrives at the emergency department cradling her arm; the deformity leaves no doubt that the bone is broken. Which of the following is the most likely reason for the fracture?
Bony metastasis to the humerus from breast cancer
Osteitis fibrosa cystica from parathyroid disease
Osteomalacia from nutritional deficiency
Osteoporosis
Primary malignant bone tumor
An 18-year-old male comes to the physician's office because of dull aching and fullness of the scrotum. Examination shows soft left-sided scrotal swelling; transillumination testing is negative. The scrotal swelling increases when the patient performs the Valsalva maneuver. The physical examination is otherwise unremarkable. Which of the following is the most likely cause of his condition?
Dilatation of pampiniform plexus
Hypoalbuminemia
Fluid in the tunica vaginalis
Testicular neoplasia
Cystic dilations of the efferent ductules
A 72-year-old man underwent surgical repair of an aneurysm of the infrarenal aorta. He received perioperative prophylaxis with a second-generation cephalosporin antibiotic. On the first postoperative day he complains of progressive abdominal pain and bloody diarrhea. His temperature is 38.5° C (101° F), blood pressure is 110/65 mm Hg, pulse is 110/min and respirations are 22/min. His abdomen is mildly distended and tender to palpation. The tenderness is mostly in the left lower quadrant without rebound. Femoral pulses are full and symmetric. His white blood cell count is 12,000/mm3. Which of the following is the most likely diagnosis?
Ischemia of the bowel
Pseudomembranous colitis
Invasive infectious diarrhea
Aortoenteric fistula
Perforation of the colon
A 32-year-old male comes to the emergency department because of a 3 day history of increasing lower abdominal pain, mild diarrhea and rectal pain on defecation. Ten days ago he had right lower quadrant (RLQ) pain for about 24 hours that resolved spontaneously. Since then, he has had malaise and low-grade fever. His temperature is 38.7°C (101.6°F), blood pressure is 150/90 mm Hg, pulse is 11 0/min and respirations are 15/min. Examination shows lower abdominal tenderness without rebound. No masses are palpable, and bowel sounds are decreased. Rectal examination shows a very tender, boggy and fluctuant bulging mass on palpation with the tip of the finger anteriorly. Laboratory studies show:Complete blood count Hemoglobin14.0 g/LPlatelets270,000/mm3Leukocyte count15,500/mm3His current condition is most likely a complication of?
Acute appendicitis
Acute diverticulitis
Anorectal abscess
Invasive diarrhea
Colon cancer
A 44-year-old man complains of vague right upper abdominal discomfort that he has had for about 1 month. He describes no other symptoms, and, except for enucleation of one eye at age 21 "for a tumor," he has been in excellent health all his life. He exercises regularly and neither smoke nor drinks. The only findings on physical examination include the artificial eye and a tender, enlarged, and nodular liver. CT scan of the upper abdomen demonstrates multiple masses within the liver. Which of the following will most likely be found on biopsy of these masses?
Metastatic malignant melanoma .
Metastatic prostatic cancer
Metastatic retinoblastoma
Metastatic sarcoma
Primary hepatocellular carcinoma
A previously healthy, intoxicated, 19-year-old man is driving a car without using a seat belt. He crashes the car into the back of a parked truck. In the process he slams his abdomen into the steering wheel and ruptures his spleen. Which of the following is the most important problem associated with this type of injury?
Internal blood loss
Bacteremia
Electrolyte abnormalities
External blood loss
Peritonitis
A 27-year-old immigrant from El Salvador has a 14 × 12 × 9 cm mass in her left breast. It has been present for 7 years and has slowly grown to its present size. The mass is firm, nontender, rubbery, and completely movable, and it is not attached to the overlying skin or the chest wall. There are no palpable axillary nodes or skin ulceration. Which of the following is the most likely diagnosis?
Cystosarcoma phyllodes
Breast cancer
Chronic cystic mastitis
Intraductal papilloma
Mammary dysplasia
A 63-year-old man, who weighs 65 kg, is in his 2nd postoperative day after an abdominoperineal resection for cancer of the rectum. An indwelling Foley catheter was left in place after surgery. The nurses are concerned because, even though his vital signs have been stable, his urinary output in the past 2 hours has been zero. In the preceding 3 hours, they had collected 56 mL, 73 mL, and 61 mL. Which of the following is the most likely diagnosis?
Plugged or kinked catheter
Damage to the bladder during the operation
Damage to the ureters during the operation
Dehydration
Acute renal failure
A 55-year-old woman falls in the shower and hurts her right shoulder. She shows up in the emergency department with her arm held close to her body, but the forearm rotated outward as if she were going to shake hands. She is in pain and will not move the arm from that position. Her shoulder looks "square" in comparison with the rounded unhurt opposite side, and there is numbness in a small area of her shoulder over the deltoid muscle. Which of the following is the most likely diagnosis?
Anterior dislocation of the shoulder
Acromioclavicular separation
Posterior dislocation of the shoulder
Scapular fracture
Fracture of the upper end of the humeral shaft
A 68-year-old man is brought to the emergency department with excruciating back pain that began suddenly 45 minutes ago. The pain is constant and is not exacerbated by sneezing or coughing. He is diaphoretic and has a systolic blood pressure of 90 mm Hg. There is an 8 cm pulsatile mass deep in his epigastrium, above the umbilicus. A chest x-ray film is unremarkable. Two years ago, he was diagnosed with prostatic cancer and was treated with orchiectomy and radiation. At that time, his blood pressure was normal, and he had a 6-cm, asymptomatic abdominal aortic aneurysm for which he declined treatment. Which of the following is the most likely diagnosis?
Rupturing abdominal aortic aneurysm
Dissecting thoracic aortic aneurysm
Fracture of lumbar pedicles with cord compression
Herniated disc
Metastatic tumor to the lumbar spine
An out-of-shape, recently divorced, 42-year-old man is trying to impress a young woman by challenging her to a game of tennis. In the middle of the game, a loud "pop" (like a gunshot) is heard, and the man falls to the ground clutching his ankle. He limps off the court with pain and swelling in the back of the lower leg. Although he can still weakly plantar-flex his foot, he seeks medical help the next day because of persistent pain, swelling, and limping. He can put weight on that foot with no exacerbation of the pain, but the motion of taking a step is painful. Which of the following would be the most likely finding on physical examination?
There is a gap in the Achilles tendon easily felt by palpation
There is crepitation and grating by direct palpation over either malleoli
The ankle joint can be adducted farther in than the normal contralateral side
The ankle joint can be abducted farther out than the normal contralateral side
Tapping on the calcaneus is extremely painful
A 27-year-old man sustained penetrating injuries of the chest and abdomen when he was repeatedly stabbed with a long ice-pick. At the time of admission, he had a right pneumothorax, for which a chest tube was placed prior to undergoing a general anesthetic for exploratory laparotomy. The operation revealed no intraabdominal injuries and was terminated sooner than had been anticipated. The patient remained intubated, waiting for the anesthetic to wear off. Because he was not moving enough air, he was placed on a respirator. Then, he suddenly went into cardiac arrest and died. All through this time he had been hemodynamically stable, and never had any signs of hypotension or arrhythmias. Which of the following was the most likely cause of the cardiac arrest?
Air embolism
Fat embolism
Myocardial infarction
Pulmonary embolus
Tension pneumothorax
A 13-year-old, obese boy complains of persistent knee pain for several weeks. The family brings him in because he has been limping. He sits in the examining table with the sole of the foot on the affected side pointing to the other leg. Physical examination is normal for the knee, but shows limited hip motion. As the hip is flexed, the leg goes into external rotation and cannot be rotated internally. Which of the following is the most likely diagnosis?
Slipped capital femoral epiphysis
Avascular necrosis of the femoral head
Developmental dysplasia of the hip
Osteogenic sarcoma of the lower femur
Tibial torsion with foot inversion
A 72-year-old man comes in complaining of persistent and nagging low back pain that he has had for several weeks. The pain seems to be increasing in intensity, is worse at night, is unrelieved by rest or positional changes, and is not exacerbated by coughing, sneezing, or straining to have a bowel movement. He is a chronic smoker, and for the past 3 months has had persistent cough with occasional bloody streaked sputum, as well as a 20-pound weight loss. On physical examination, he is distinctly tender to palpation at a particular spot over his lower thoracic spine. Which of the following is the most likely diagnosis?
Metastatic tumor to the thoracic spine
Ankylosing spondylitis
Herniated disk
Multiple myeloma
Primary malignant bone tumor
The unrestrained front-seat passenger in a car that crashed at high speed arrives at the emergency department with signs of moderate respiratory distress. Physical examination shows no breath sounds at all on the left hemithorax. Percussion is unremarkable, and his vital signs are normal. A chest x-ray film shows a collapsed left lung and multiple air-fluid levels filling the left pleural cavity. A nasogastric tube that had been placed prior to taking the film shows the tube reaching the upper abdomen and then curling up into the left chest. Which of the following is the most likely diagnosis?
Left diaphragmatic rupture
Blow out of pulmonary blebs
Esophageal rupture or perforation
Left hemopneumothorax
Major injury to the tracheobronchial tree
A 67-year-old man shows up in the emergency department because he has not been able to void for the past 12 hours. He feels the need to, but he cannot do it. He gives a history that, for several years now, he has been getting up four or five times a night to urinate. It would take him a considerable time to get the urinary stream going, and the stream lacked force and often ended in a dribble. Because of a cold, 2 days ago he began taking an antihistamine, taking a decongestant, and drinking plenty of fluids. Physical examination shows a palpable, smooth, round mass arising from the pubis and reaching about half way toward the umbilicus. The mass is dull to percussion, and pushing on it accentuates the feeling of needing to void. Rectal examination reveals a large, boggy, non-tender prostate gland without nodules. This a classic presentation for which of the following acute conditions?
Urinary retention in a patient with benign prostatic hypertrophy
Urinary retention in a patient with prostatic cancer
Bacterial prostatitis
Cystitis in a patient with bladder cancer
Renal failure
Several months after sustaining a crushing injury to his arm, a patient complains bitterly about constant, burning, agonizing pain in that arm, that does not respond to the usual analgesic medications. The pain in his arm is aggravated by the slightest stimulation of the area, such as rubbing from the shirt sleeves. The arm is cold, cyanotic, and moist, but it is not swollen. Pulses at the wrist are normal, and neurologic function of the three major nerves is intact. Which of the following is most appropriate to provide diagnostic confirmation of the nature of the problem and eventual therapy?
Sympathetic block and surgical sympathectomy
Angiogram and subclavian vein bypass .
Doppler studies and arterial reconstruction
Doppler studies and fasciotomy
Cervical spine x-rays and cervical rib resection
A 57-year-old alcoholic man is being treated for acute hemorrhagic pancreatitis. He was in the intensive care unit for 1 week, where he required chest tubes for pleural effusions and was on a respirator for several days. Eventually, he improved sufficiently to be transferred to the floor. Three days after leaving the unit, and about 2 weeks after the onset of the disease, he spikes a fever and develops leukocytosis. Which of the following developments do these recent findings most likely suggest?
Pancreatic abscess
Chronic pancreatitis
Pancreatic pseudocyst
Pelvic abscess
Subphrenic abscess
A 33-year-old woman is involved in a high-speed automobile collision. She arrives at the emergency department gasping for breath. Her lips are cyanotic and she has flaring nostrils. There are bruises over both sides of the chest, and tenderness suggestive of multiple rib fractures. Her blood pressure is 60/45 mm Hg, pulse is 160/min and feeble and central venous pressure is 25 cm H2O. Her neck and forehead veins are distended. She is diaphoretic and has a hint of subcutaneous emphysema in the lower neck and upper chest. Her left hemithorax has no breath sounds and is hyper resonant to percussion. The trachea is deviated to the right, as are the heart sounds. Which of the following is the most likely diagnosis?
Tension pneumothorax caused by lung punctured by broken ribs
Massive mediastinal bleeding from ruptured aorta
Massive intrapleural bleeding from torn intercostal vessels
Flail chest due to multiple rib fractures
Air embolism from tracheobronchial injuries
A 32-year-old male is rushed to the emergency room after a motor vehicle accident. He was driving 55 mph when he suddenly lost control of his vehicle and hit a tree. He was wearing a seat belt. On physical examination, the patient appears scared and complains of moderate chest and abdominal discomfort. His voice is soft. His blood pressure is 190/ 100 mmHg and his heart rate is 100/min. The pupils are symmetric and reactive to light and the trachea is midline. You note bruising over the chest and upper abdomen. No penetrating injuries are evident. Which of the following injuries is most likely in this patient?
Aortic rupture
Esophageal rupture
Tracheobronchial disruption
Vagus nerve disruption
Pulmonary contusion
A 23-year-old male is brought to the emergency department following a motor vehicle accident (MVA) where he was the unrestrained driver. The patient was found unresponsive at the scene and was intubated by paramedics. He receives 2.5L of normal saline over the 20 minutes before he reaches the ED. His blood pressure there is 70/30 mmHg and his heart rate is 120/min. On physical examination, he responds to strong vocal and tactile stimuli by opening his eyes. His pupils are equal and reactive to light. There are multiple bruises over the anterior chest and upper abdomen. His neck veins are flat, trachea is midline and extremities are cold. Cardiac monitoring shows sinus tachycardia. Which of the following is the most likely cause of this patient's current condition?
Loss of intravascular volume
Loss of vascular tone
Air embolism
Ventricular filling restriction
Impaired myocardial contractility
A 33-year-old male falls while riding his bicycle in the park, and presents to the emergency department. Physical examination reveals upper abdominal bruises. His abdomen is non-distended, soft, and mildly tender in the epigastrium. Abdominal CT scan does not reveal any abnormalities. The patient is sent home with analgesic medications. He returns one week later with fever, shaking chills, poor appetite and deep abdominal pain Which of the following is most likely related to this patient's symptoms?
Pancreatic laceration
Spleen rupture
Stomach perforation
Small bowel necrosis
Meckel diverticulitis
A 36-year-old woman presents to the emergency department with severe epigastric pain and right shoulder pain of about two hours duration. She also reports having one episode of emesis. When asked about her diet, she explains that she unintentionally fasted yesterday and had a large meal two hours ago. Her past medical history is significant for frequent heartburn for which she takes ranitidine. Several hours after presenting, the patient's pain resolves completely. Which of the following best explains this episode?
Viscus distention
Acid hypersecretion
Peritoneal irritation
Mucosal inflammation
Vascular obstruction
A 74-year-old male is undergoing elective abdominal aortic aneurysm repair. He is given two units of packed red blood cells during the surgery. He develops fever and chills one hour after finishing the surgery and transfusion. He received one dose of prophylactic antibiotics before surgery. He had coronary bypass grafting two months ago. His temperature is 38.5C (101.3F), blood pressure is 130/76 mm Hg, pulse is 90/min and respirations are 16/min. Physical examination shows a mildly tender wound; there is no redness. The lungs are clearto auscultation. He has a Foley catheter and right subclavian central venous access, each placed at the time of surgery. Which of the following is the most likely cause of his fever?
Transfusion reaction
Nosocomial pneumonia
Drug fever
Urinary tract infection
Catheter associated infection
A 55-year-old male comes to the physician's office because of chronic pain in his buttock, hip and thigh muscles. The aching pain is present in both legs and usually is associated with walking. He has multiple medical problems and takes several medications. He has a 30 pack year smoking history. His temperature is 36.7C (98F), blood pressure is 150/88 mm Hg, pulse is 80/min and respirations are 16/min. Examination shows decreased femoral, popliteal and dorsalis pedis pulses in both legs. Which of the following additional complaints is most likely in this patient?
Impotence
Snoring
Headache
Anorexia
Ankle swelling
A 23-year-old male is brought to the emergency department after a motor vehicle accident. He was an unrestrained driver. He was found unresponsive at the scene of the accident, and was intubated by the paramedics. He has received 2L of normal saline over the last 20 minutes. His blood pressure is 80/40 mmHg, and heart rate is 120/min. He responds to strong vocal and tactile stimuli by opening his eyes. His pupils are equal and reactive to light. His neck veins are distended. There are multiple bruises involving the anterior chest and upper abdomen. His chest x-ray shows a small, left-sided pleural effusion and normal cardiac contours. Which of the following is the most likely diagnosis?
Pericardial tamponade
Lung contusion
Aortic rupture
Esophageal rupture
Bronchial rupture
A 65-year-old male comes to the ER because of sudden onset severe pain in his right leg. He says he has never previously had pain in his leg and denies any recent trauma, fever or chills. He recently suffered an acute anterior wall myocardial infarction that resulted in cardiogenic shock and is currently undergoing cardiac rehabilitation. His other medical problems include hypertension, diabetes and hyperlipidemia. His temperature is 36.7C (98F), blood pressure is 110/70 mm Hg, pulse is 90/min (regular) and respirations are 16/min. His lungs are clear to auscultation. His heart rate is regular with no murmurs. Below the knee the right leg is cool to touch and appears pale. The dorsalis pedis pulse is not palpable while the popliteal pulses are full. Pulses are normal in the contralateral extremity. Neurologic examination shows numbness over the dorsum of the leg and foot. Which of the following is the most likely cause of his symptoms?
Arterial embolism
Nerve compression
Arterial thrombosis
Venous thrombosis
Arterial vasculitis
An 88-year-old male complains of severe right calf pain several hours after undergoing a right femoral artery embolectomy. He also complains of a burning sensation in his posterior right leg. He has a long history of atrial fibrillation and hypertension. His past medical history also includes stroke, bleeding duodenal ulcer, diabetes mellitus and diabetic nephropathy. On physical examination, his blood pressure is 160/70 mm Hg and his heart rate is 100 per minute and irregular. His right calf is swollen, tense and exquisitely tender; the pain is worsened by passive extension of the right knee. Dorsalis pedis and posterior tibial pulses are palpable in the bilateral lower extremities. Which of the following is the most likely cause of this patient's symptoms?
Soft tissue swelling
Recurrent embolism
Venous thrombosis .
Bone infarction
Anaerobic infection
A 62-year-old man is brought to the emergency department after being involved in a motor vehicle collision where he suffered serious burns. On physical examination there are second degree burns covering both upper extremities and third degree burns over the anterior aspects of both lower extremities. On day three of his hospitalization, the patient develops tachycardia and decreased urine output. His blood pressure is 90/60 mmHg, pulse is 120/min, temperature is 95°F (35°C), and respirations are 26/min. Laboratory analysis reveals: Blood glucose 230 mg/dL, WBC 16,000/mm3, Platelets 80,000/mm3. Which of the following is the best explanation for this patient's current condition?
Bacterial infection
Myocardial injury
Extensive protein breakdown
Immune reaction to heterologous proteins
Renal glomerular injury
A 36-year-old male presents with firm, non-tender swelling of his right cheek. He tells you that he had similar swelling at that site two years ago and was diagnosed with a tumor, which was subsequently removed without complication. Examination reveals fullness of the parapharyngeal space on the right side. Repeat surgery in this patient is most likely to result in which of the following complications?
Facial droop
Hoarseness
Tic douloureux
Tongue palsy
Jaw asymmetry
A 43-year-old male complains of right shoulder pain and weakness after falling on his outstretched hands two days ago. He denies any swelling or shoulder deformity. You passively abduct both his arms above his head and then ask him to bring his arms down slowly in an adducting motion. The right arm drops rapidly at the midpoint of its descent. What is the most likely diagnosis?
Rotator cuff tear
Biceps tendon tear
Lower brachial trunk injury
Humoral neck fracture
Long thoracic nerve
A 32-year-old female presents with intermittent blood staining of her bra from her left breast. She has not felt any lumps on either breast. Physical examination shows no breast mass or axillary lymphadenopathy. Ultrasonogram of the breast is within normal limits. Which of the following is the most likely diagnosis?
Intraductal papilloma
Fibrocystic changes
Fibroadenoma
Ductal carcinoma in situ
Hyperprolactinemia
A 31-year-old male presents to your office with pain and swelling over his coccyx. He has never had symptoms like this before. His past medical history is significant for an appendectomy two years ago and acute pyelonephritis one year ago. Which of the following is the most likely diagnosis?
Pilonidal disease
Perianal abscess
Crohn's disease
Suppurative hidradenitis
Bowen's disease
An 18-year-old male comes to the physician's office because of dull aching and fullness of the scrotum. Examination shows soft testicular swelling; transillumination testing is negative. The scrotal swelling increases when the patient performs the Valsalva maneuver. The physical examination is otherwise unremarkable. Which of the following is the most likely cause of his condition?
Dilatation of pampiniform plexus
Hypoalbuminemia
Fluid in the tunica vaginalis
Testicular neoplasia
Cystic dilations of the efferent ductules
A 12-year-old boy is brought to the emergency department after being involved in a motor vehicle collision. He is in no distress and is admitted for observation. Two hours after admission, he develops tachypnea and tachycardia. His temperature is 36.7C (98F), blood pressure is 110/66 mm Hg, pulse is 110/min, and respirations are 22/min. Examination shows bruises on the right side of the chest, but palpation of the ribs does not elicit pain or suspicion for rib fractures. Breath sounds are decreased on the right side. ABG on 6 liters of oxygen shows PO2 of 60 mm Hg, PCO2 of 32 mm Hg, and pH of 7.42. An x-ray film of the chest shows a patchy irregular alveolar infiltrate in the right middle and lower lobes. Which of the following is the most likely diagnosis?
Pulmonary contusion
Adult respiratory distress syndrome
Aspiration pneumonia
Fat embolism
Hemothorax
A 31-year-old male is brought to the emergency department after being involved in a motor vehicle collision as an unrestrained passenger. He was given 3L of normal saline in the ambulance on his way to the hospital and has been receiving 5 L/min of oxygen by nasal cannula. He is agitated and moves all four extremities spontaneously. His blood pressure is 85/55 mmHg and his heart rate is 120/min. His respiratory rate is 30/min. His pupils are symmetric and reactive to light. His neck veins are flat and his trachea is shifted slightly to the right. Over the left hemithorax, breath sounds are absent and there is dullness to percussion. Which of the following diagnoses is most likely?
Hemothorax
Tension pneumothorax
Lung contusion
Lung atelectasis
Diaphragmatic rupture
A 45-year-old policeman presents to your office complaining of tiredness and sleepiness. He says that his job seems tiring to him recently. It is difficult for him to get up in the morning and go to work. He goes to bed early because he feels tired and sleepy. Two months ago, he was investigating a case of massive murder. He slipped on the blood on the floor, fell and hit his head. He also describes recent abdominal pain that is constant and gnawing, interfering with his sleep. His appetite is poor, and he lost 15 pounds over the last month. Physical examination is significant only for tenderness and fullness in the epigastrium. Which of the following is the most likely diagnosis?
Pancreatic cancer
Duodenal ulcer
Major depressive episode
Post-traumatic stress disorder
Chronic subdural hematoma
A 54-year-old female with a 30 pack-year smoking history undergoes cholecystectomy after an episode of biliary pancreatitis. On the third postoperative day, she complains of discomfort in the upper abdomen. Though she is breathing comfortably, her oxygen saturation is 90%, compared with 98% yesterday. Her blood pressure is 130/80 mmHg, heart rate is 90/min, respiratory rate is 20/min, and temperature is 98F (36C). Arterial blood gas analysis reveals the following: pH = 7.44, p02 =64 mmHg, pC02 =34 mmHg, which of the following most likely explains the observed findings?
Impaired cough and deep breathing
Aspiration of gastric secretions
Bronchial wall edema and bronchospasm
Ventilator-associated pneumonia
Diaphragmatic paralysis
A 35-year-old male presents with complaints of muscle weakness and sensory loss in his upper extremities. His medical history is significant for involvement in a motor vehicle accident seven years ago in which he sustained a whiplash cervical spine injury. Physical examination today reveals moderate wasting of the small hand muscles and impaired pain and temperature sensation in the bilateral upper extremities. Light touch, vibration, and position senses are all intact. Which of the following is the most likely diagnosis?
Syringomyelia
Amyotrophic lateral sclerosis
Cervical spondylosis
Intervertebral disk prolapse
Multiple sclerosis
A 45-year-old male presents to his physician with persistent nausea and vomiting of partially digested food for the past month. He has also lost 5 lbs of weight during this period of time. His appetite is good but he feels full after a few bites. His past medical history is significant for a one-year history of type 2 diabetes and a suicide attempt 6 months ago in which he ingested acid. He drinks alcohol and smokes one pack of cigarettes daily. His temperature is 36.80C (98.20 F), blood pressure is 110/65 mm Hg, pulse is 110/min, and respirations are 16/min. Mucous membranes are dry. Examination shows succussion splash on the epigastrium. Which of the following is the most likely diagnosis?
Pyloric stricture
Diabetic gastroparesis
Esophageal stricture
Duodenal carcinoma
Duodenal hematoma
A 34-year-old male undergoes successful laparotomy for a gun-shot wound. He received 5 units of packed red blood cells during the surgery. He has been receiving incentive spirometry and ampicillin/sulbactam. However, he developed a fever of 38.7C (101.7F) on the sixth postoperative day. His blood pressure is 120/76 mm Hg, pulse is 97/min and respirations are 14/min. Examination shows an alert, pleasant male in no acute distress. The oropharynx is clear. The lungs and heart are clear to auscultation. The abdomen is soft and non-tender, and the wound has no discharge. He has a right femoral triple lumen catheter and Foley catheter in place. Extremities have no swelling or redness. Two days later, four bottles of blood cultures grew coagulase negative Staphylococcus. Which of the following is the most likely cause of his fever?
Catheter associated infection
Urinary tract infection
Clostridium difficile infection
Cerebral hemorrhage
Neoplastic fever
An overweight 12-year-old boy presents with left knee pain that has been going on intermittently for the past three months. Physical activity, especially stair climbing, exacerbates the pain. The boy's mother also points out that he has been limping recently. On physical examination, his anterior left hip is moderately tender to palpation, and when he is asked to stand on his left leg, the right half of his pelvis tilts downward. Which of the following best explains this finding?
Tensor fascia lata weakness
Gluteus muscle weakness
Psoas muscle weakness
Quadratus lumborum weakness
Quadriceps muscle weakness
A 23-year-old woman comes to the physician because of a 4-week history of a whistling noise during respiration. She underwent a difficult rhinoplasty a few months ago. The noise is getting louder and is annoying. Which of the following is the most likely diagnosis?
Nasal septal perforation
Nasal polyp
Allergic rhinitis
Nasal furunculosis
Nasal foreign body
A 46-year-old man is brought to the emergency department after being involved in a motor vehicle collision. He is unresponsive. His injuries include a basilar skull fracture, brain contusion, fractures of ribs 7-10, hemopneumothorax on the right and a pelvic fracture. After placement of a chest tube and pelvis fixation, his condition stabilized. On the fifth day of his hospital stay, he is still unresponsive with a Glasgow Coma Scale of 8. He is breathing spontaneously. Examination shows an abnormal facial reaction to abdominal palpation. Pain appears to be elicited by palpation in right upper quadrant. Bowel sounds are diminished. Rectal examination shows no abnormalities. Nasogastric tube aspiration shows retention of gastric contents. An abdominal CT scan shows gaseous distention of the small and large bowels without airfluid levels. The gall bladder is distended and pericholecystic fluid is present. Stones are not seen. Which of the following is the most likely diagnosis?
Cholecystitis
Bowel obstruction
Pancreatitis
Mesenteric contusion
Lung contusion
A 77-year-old woman is brought to the emergency department because of sudden-onset intense diffuse abdominal pain followed by vomiting. Her past medical history is significant for chronic uncontrolled hypertension, cerebrovascular accident, diabetes and hyperlipidemia. She takes multiple medications. She does not use tobacco, alcohol or drugs. Her temperature is 38.30 C (1010 F), blood pressure is 180/100 mm Hg, pulse is 110/min and irregular and her respirations are 22/min. She is in severe distress. Lungs are clear to auscultation. Abdominal examination shows severe pain to palpation and nearly absent bowel sounds. There is rigidity and rebound. Rectal examination shows heme-positive stools. EKG shows absent P waves, irregular rhythm and inverted T waves. There are no previous EKGs for comparison. An x-ray film of the chest shows cardiomegaly. Laboratory studies show: Hematocrit 49%, Leukocyte count 77,500/mm3, Troponin I normal. What is the most likely diagnosis?
Bowel infarction
Acute cholecystitis
Ruptured abdominal aortic aneurysm
Myocardial infarction
Acute pancreatitis
A 35-year-old man is brought to the emergency department after being involved in a motor vehicle collision. He is unconscious. His blood pressure is 100/50 mm Hg, pulse is 100/min, and respirations are 19/min. Examination shows bilaterally reactive and non-dilated pupils. He does not follow commands and makes inappropriate sounds. A CT scan of the head shows numerous minute punctuate hemorrhages with blurring of the gray-white matter interface. Which of the following is the most likely diagnosis?
Diffuse axonal injury
Epidural hematoma
Subdural hematoma
Multiple sclerosis
Subarachnoid hemorrhage
A 65-year-old man with cervical spondylosis secondary to degenerative changes in the cervical spine was admitted after being involved in a motor vehicle accident. He regained consciousness after 5 minutes. After regaining consciousness, he had complete weakness in both upper extremities but was able to move his lower extremities. Vital signs are stable. Plain x-ray films of the cervical spine show no abnormalities except those consistent with mild degenerative changes. Which of the following is the most likely diagnosis?
Central cord syndrome
Brown-Sequard syndrome
Cerebral contusion
Posterior spinal cord syndrome
Anterior spinal cord syndrome
A 54-year-old alcoholic man comes to the emergency department because of dysphagia, drooling and a fever. He has been sick for two days and has not been able to eat. His mouth is swollen and feels hot. Examination shows a pale, febrile man who is drooling. There is redness around the entire mouth extending into the floor of the mouth. A tender, symmetric and indurated swelling with palpable crepitus is present in the submandibular area. Laboratory study shows an elevated W BC count. Which of the following is the most likely source of the oral cavity infection?
Teeth
Blood
Lungs
Parotid gland
Tonsils
A 69-year-old man is evaluated after undergoing an elective repair of a rapidly expanding abdominal aortic aneurysm. The surgical procedure was complicated by a significant amount of blood loss and required multiple transfusions. In the postoperative recovery room, he had weakness in both lower extremities and developed urinary retention. Neurologic examination shows spastic paraplegia and loss of pain sensation over the lower extremities; vibratory sensation is intact. Upper extremity examination shows no abnormalities. Which of the following is the most likely pathophysiologic mechanism of the neurologic dysfunction?
Spinal cord ischemia
Hematoma compressing the spinal cord .
Mechanical damage of the spinal cord .
Conversion disorder
Mechanical damage to the peripheral nerves
A 24-year-old woman comes to the physician because of a one-week history of increasing pain in the right leg. She is an active dancer and practices 4-5 hours a day. One week ago, she felt a dull aching pain in the right middle leg; the pain has been increasing since and is particularly bad when she dances. The pain is interfering with her dancing sessions. She is afebrile and her other vital signs are within normal limits. Examination shows point tenderness over the midpoint of the right leg; there are no abnormalities of the skin overlying the tender point. Knee and ankle examinations show no abnormalities. An x-ray of the lower leg shows no abnormalities. ESR is within normal limits. Which of the following is the most likely cause of her pain?
Stress fracture
Ligamentous tear
Bone infection
Nerve entrapment
Bone neoplasm
A 32-year-old male comes to the emergency department because of a 3 day history of increasing lower abdominal pain, mild diarrhea and rectal pain on defecation. Ten days ago he had right lower quadrant (RLQ) pain for about 24 hours that resolved spontaneously. Since then, he has had malaise and low-grade fever. His temperature is 38.70C (101.60F), blood pressure is 150/90 mm Hg, pulse is 110/min and respirations are 15/min. Examination shows lower abdominal tenderness without rebound. No masses are palpable, and bowel sounds are decreased. Rectal examination shows a very tender, boggy and fluctuant bulging on palpation with the tip of the finger anteriorly. Laboratory studies show: Complete blood count: Hemoglobin 14.0 g/L, Platelets 270,000/mm3, Leukocyte count 15,500/mm3, His current condition is most likely a complication of?
Acute appendicitis
Anorectal abscess
Invasive diarrhea
Acute diverticulitis
Colon cancer
A 70-year-old male rushed to the emergency department because of bright red bleeding per rectum. He says his commode is full of blood and has never experienced any bleeding before. He has a history of constipation. He takes daily aspirin for prevention of stroke and hydrochlorothiazide for high blood pressure. His temperature is 36.50C (97.80F), blood pressure is 100/60 mm Hg, pulse is 120/min and respirations are 20/min. He is not hypoxic. Abdomen is soft, non-distended and non-tender; no masses or organomegaly are palpated; bowel sounds are normal. Rectal examination shows bright red blood and an enlarged prostate. Nasogastric tube aspirate shows non-bilious stomach contents without blood. An x-ray of the abdomen shows no abnormalities. Which of the following is the most likely cause of his bleeding?
Diverticulosis
Peptic ulcer disease
Mesenteric thrombosis
Colon cancer
Ischemic colitis
An 11-year-old boy is brought to the emergency department for evaluation of an injury from jumping off a 10 ft wall, 2 days ago. He had some pain in his feet immediately following the jump, but was able to walk. The past 2 days, he has had increasing pain in his right foot with walking. He has no pain at rest. He has some "crunching" in the right foot. Physical examination shows the foot appears normal with the exception of suffusion on the plantar surface. Passive motion of the second toe and passive dorsiflexion of the foot produces pain in the middle of the foot. Which of the following is the most likely diagnosis?
Fracture of second metatarsal
Stress fracture of second metatarsal
Tenosynoviitis of toe flexors
Hematoma in middle plantar space
Metatarsophalangeal joint dislocation
An 18-year-old woman at 9 weeks' gestation is brought to the emergency department because of an open fracture of the tibia and fibula. She is hemodynamically stabilized and referred to the orthopedic department. She is scheduled for internal fixation of the tibia for the following day. However, before the surgery she develops severe dyspnea and confusion. Her temperature is 37.70C (99.90F), blood pressure is 110/70 mm Hg, pulse is 110/min, and respirations are 22/min. Examination shows numerous non-palpable petechiae in the upper part of the body. Which of the following is the most likely diagnosis?
Fat embolism
Air embolism
Amniotic fluid embolism
Thromboembolism
Acute respiratory distress syndrome
A 55-year-old man comes to the physician because of a 4-month history of an ulcer on the sole of his right foot. He has had no trauma and does not remember how he got the ulcer. He states the ulcer has been difficult to heal and readily gets infected. He does not use tobacco, alcohol or drugs. Examination shows the ulcer is located on the sole of his foot just below the head of the first metatarsal bone. His foot is warm and dry and appears slightly deformed. Dorsalis pedis pulses are present. Which of the following is the most likely cause of his condition?
Peripheral neuropathy
Venous hypertension
Arterial spasm
Central spinal cord lesion
Posterior spinal cord lesion
A 7-year-old child is brought to the emergency department after being involved in a highway motor vehicle collision. He had blunt trauma to his abdomen. Vital signs are stable, except for a respiratory rate of 30 per minute. Physical examination shows bruising of the upper abdomen, abdominal distention, and tenderness. He is in moderate respiratory distress; breath sounds are decreased on the left side. Chest tube placement shows no blood or air in the pleural cavity. An x-ray film of the chest shows an elevated left hemidiaphragm. Laboratory studies show hemoglobin and hematocrit within normal limits. Which of the following is the most likely diagnosis?
Diaphragmatic hernia
Tension pneumothorax
Hemothorax
Pulmonary contusion .
Laceration of the liver
A 25-year-old motorcyclist is brought to the emergency department after being involved in a collision with an automobile. On arrival he is in obvious pain. He expresses an urge to void, but is unable to do so. Genital examination shows blood at the urethral meatus and a scrotal hematoma. Rectal examination reveals a high riding prostate. Abdominal examination is suggestive of a distended bladder. Which of the following is the most likely diagnosis?
Urethral injury
Intraperitoneal bladder rupture
Extraperitoneal bladder injury
Fracture of penis
Renal injury
A 43-year-old mildly overweight female complains of periodic right knee swelling and pain with physical activity for the past three months. She says that this problem started while on a hiking trip three months ago, at which point she experienced a 'popping' sensation in her right knee. She recalls that her knee was swollen the next day, and responded to over-the-counter pain killers. Recently, she has been having to limit her physical activities due to knee pain. On physical examination, there is tenderness of the anterior and medial right knee joint. Which of the following is the most likely diagnosis?
Meniscal tear
Anterior cruciate ligament tear
Osteoarthritis
Patellar tendonitis
Anserine bursitis
A 35-year-old black man is brought to the emergency department after a motorcycle accident. He hit the street with the side of his head. He was found unconscious when the emergency medical team arrived. However, on the way to the emergency department he regains consciousness. Upon arrival he is confused and complains of a headache. His temperature is 36.9C (98.5F), blood pressure is 100/60 mm Hg, pulse is 110/min, and respirations are 22/min. Examination shows a dilated pupil on the right side, with some weakness of the left arm and leg. CT scan of the head shows a biconvex hematoma on the right side of the head. Which of the following is the most likely diagnosis?
Acute epidural hematoma
Acute subdural hematoma
Basilar fracture of skull
Intracerebral bleeding
Subarachnoid hemorrhage
A 54-year-old man is brought to the emergency department 1 0 minutes after being involved in a motor vehicle collision. On arrival, he is breathing spontaneously, is non-cyanotic and has no signs of external injury. His temperature is 37C (98.6F), blood pressure is 104/50 mm Hg, pulse is 122/min and respirations are 16/min. Examination shows bilateral round and reactive pupils of 4 mm. He is making some incomprehensible sounds. He responds to his name by opening his eyes and on applying supraorbital pressure he extends his left extremity and grasps your hand with his right hand. What is the Glasgow coma scale (GCS) in this patient?
10
6
8
12
14
A four-year-old boy is brought to the physician because of discomfort in the left hip and left knee that is causing him to limp. Examination shows normal knee joints bilaterally, but there is marked limitation of internal rotation and abduction of the left hip. His temperature is 37.1 C (98.6F), blood pressure is 90/60 mm Hg, pulse is 80/min and respirations are 16/min. Laboratory studies including complete blood count and basic metabolic profile show no abnormalities. Which of the following is the most likely diagnosis?
Legg-Calve-Perthes disease
Hematogenous osteomyelitis
Slipped capital femoral epiphysis
Septic arthritis of the hip joint
Developmental dysplasia of the hip
A 65-year-old male is being evaluated for hip pain. The pain has been present for several months and is constant. He denies any weight loss or loss of appetite. His past medical history is significant only for high blood pressure. His temperature is 37.2 C (98.9 F), blood pressure is 150/88 mm Hg, pulse is 80/min and respirations are 12/min. Physical examination is unremarkable. Laboratory studies show: Alkaline phosphatase Elevated, Gamma glutamyl, transferase Normal, Serum calcium Normal, 2,5 (OH)2 vitamin D Normal. Bone scan shows increased uptake in several spots. This patient is at high risk of developing?
Hearing loss
Subarachnoid hemorrhage
Carpal tunnel syndrome
Pulmonary hemorrhage
Renal cell carcinoma .
A 78-year-old diabetic man has undergone surgical repair of a large abdominal aortic aneurysm. Postoperatively, he develops left lower quadrant abdominal pain followed by bloody diarrhea. He has a history of prostate cancer and received radiation therapy several years ago. He eats a low fiber diet. He quit smoking recently. Vital signs show a low grade fever. Examination shows tenderness in the left lower quadrant and rectal examination reveals blood in the stool. CT scan of the abdomen demonstrates thickening of the colon at the rectosigmoid junction. On colonoscopy, ulcerations are seen in the same area while the colon above and below the lesions is completely normal. Which of the following is the most likely cause of his symptoms?
Ischemic colitis
Acute diverticulitis
Radiation proctitis
Clostridium difficile colitis
Lnflammatory bowel disease
A 34-year-old man comes to the physician after being involved in a street fight. He has a painful and swollen left arm. Neurovascular examination shows no abnormalities. An x-ray film of the arm shows a fracture of the midshaft of the humerus. Closed reduction of the facture is done and the arm is kept in a hanging cast. One hour later he has numbness of the left wrist and marked limitation of extension at the wrist. Which of the following is the most likely diagnosis?
Radial nerve injury
Brachial artery injury
Compartment syndrome
Ulnar nerve injury
Median nerve injury
A 35-year-old man is brought to the emergency department after he jumped from the fourth floor of a burning building. His temperature is 36.9C (98.5F), blood pressure is 90/40, pulse is 90/min, and respirations are 20/min. Examination shows a fracture of the right tibia. He is conscious and his pupils are bilaterally equal and reactive to light and accommodation. His neurological examination shows paraplegia, with loss of pain and temperature in both legs but normal proprioception. Upper extremities do not show any neurological deficits. Passive straight leg raising test is negative. A CT scan of the spine shows a burst fracture at the level of the fourth thoracic vertebra. Which of the following is the most likely diagnosis?
Anterior cord syndrome
Central cord syndrome
Brown Sequard syndrome
Acute disk prolapse
Cauda equine syndrome
A 32-year-old man comes to the emergency room (ER) because of acute onset left flank pain, hematuria and vomiting. His pain is relieved with ketorolac in the ER. He has a history of abdominal pain due to Crohn disease, but that pain was always in the rightlower quadrant and was never this severe. His temperature is 36.8C (98.2F), blood pressure is 120/65 mm Hg, pulse is 110/min and respirations are 16/min. Chest auscultation is clear. Abdomen is soft and mildly tender over the left flank. He has no rebound or rigidity. Bowel sounds are decreased. A laparotomy scar is present in right lower quadrant. Which of the following is the most likely cause of his symptoms?
Increased absorption of oxalate
Increased recycling of bile salts and fatty acids
Increased absorption of calcium
Increased parathyroid hormone activity
Recurrent bacterial infection in the kidney
A 54-year-old man comes to the physician because of edema of his right ankle. He reports heaviness and cramping in the same leg that is worse after a long day at work. The swelling is usually reduced significantly when he wakes up in the morning and worsens progressively throughout the day. He denies any other symptoms. He has no significant medical problems except hypertension, for which he takes atenolol. His temperature is 36.7C (98F), blood pressure is 120/76 mm Hg, pulse is 80/min and respirations are 16/min. JVP is normal. Lungs are clearto auscultation. There are no murmurs. There is no hepatosplenomegaly. Examination shows edema of the right ankle. Doppler examination of the leg shows no evidence of thrombosis W hich of the following is the most likely cause of his edema?
Venous valve incompetence
Lymphatic obstruction
Impaired cardiac contraction
Reduced diastolic filling of the heart
Increased urinary loss of protein
A 30-year-old man comes to the physician because of a 2-week history of swelling and pain in the right knee. He first experienced pain when he twisted his leg while playing football 15 days ago. He felt something 'popping' in the knee at that time but ignored it. The pain and swelling has been increasing since, and he feels sudden pain with extension of his leg. Examination shows the right knee is swollen and tender along the medial side. Full extension of the right knee is not possible due to sudden pain during terminal extension. Snapping can be felt in the right knee on tibial torsion with the knee flexed at 90 degrees. An x-ray film of the knee joint shows no abnormalities. Which of the following is the most likely diagnosis?
Medial meniscus tear
Lateral collateral ligament tear
Medial collateral ligament tear
Posterior cruciate ligament injury
Anterior cruciate ligament injury
A 46-year-old male is brought to the emergency department after falling on his head and back during a downhill bike race and losing consciousness for 1 minute. He has severe back and abdominal pain. AP and lateral skull films show no abnormalities. Lumbar films show anterior compression wedge fractures of the bodies of L1 and L2. A brace is placed. CT scan of the abdomen shows a mild retroperitoneal bleed and splenic laceration. During the hospitalization he was treated conservatively with analgesics and supportive measures. On hospital day 3, he started to have abdominal distention, pain and nausea. His last bowel movement was 4 days ago and he is not passing gas. His abdomen is distended, tympanic and mildly tender without rebound or guarding. Bowel sounds are absent. An x-ray film of the abdomen is shown below: Which of the following is the most likely diagnosis?
Untitled
Paralytic ileus
Functional constipation
Large bowel obstruction
Peritonitis
Worsening hematoma
A 55-year-old male Asian immigrant presents to the physician because of recent-onset neck swelling. He also notes having several episodes of epistaxis lately. He has not sustained any trauma to the neck or nose. His past medical history is significant for syphilis and recurrent bacterial sinusitis. He drinks 2 beers daily and has a 30-pack year smoking history. He takes daily multivitamins with antioxidants. On physical examination, you note a mass in the posterior nasal cavity. Biopsy shows undifferentiated carcinoma. Which of the following is a risk factor for this cancer?
Viral infection
Alcohol use
Spirochete infection
Bacterial infection
Vitamin supplements
A 12-year-old boy is brought to the emergency department after falling from a tree. Examination shows tenderness and swelling over the left lower arm. An x-ray film of the arm shows a fracture of the distal end of the humerus with proximal and posterior displacement of the distal fracture segment. Closed reduction of the fracture is performed. However, postoperatively the patient complains of increasing pain in the left arm and forearm. Twelve hours postoperatively his forearm is pale and cold. There is marked pain on passive extension of the fingers. Which of the following is the potential dreaded complication of this condition?
Volkmann ischemic contracture
Malunion with alteration of carrying angle
Non-union
Reflex sympathetic dystrophy
Sudeck's atrophy
A 7-year-old boy has been complaining of left hip pain for the past 8 months. Over recent weeks, he has developed a limp. When you examine his gait, you note that he takes short steps with his left leg. On physical examination, his left hip has significantly limited range of motion, and there is atrophy of the left proximal thigh muscle. X-ray of the patient's pelvis is shown below: W hich of the following is most likely responsible for this patient's condition?
Untitled
Osteonecrosis
Slipped epiphysis
Bone infection
Muscle dystrophy
Synovitis
A 73-year-old man comes to the physician because of right anterior thigh pain that is worse with walking. He has a history of stable angina, hypertension, hypercholesterolemia, and COPD with periodic exacerbations. He takes ipratropium, aspirin, metoprolol and pravastatin. He smokes 2 packs a day and drinks alcohol occasionally. Physical examination shows a small pulsatile mass in the right groin area. Which of the following is the most likely diagnosis?
Femoral artery aneurysm
Femoral vein aneurysm
Indirect inguinal hernia
Direct inguinal hernia
Femoral hernia
A 72-year-old man underwent surgical repair of an aneurysm of the infrarenal aorta. He received perioperative prophylaxis with a second-generation cephalosporin antibiotic. On the first postoperative day he complains of progressive abdominal pain and bloody diarrhea. His temperature is 38.5C (101F), blood pressure is 110/65 mm Hg, pulse is 110/min and respirations are 22/min. His abdomen is mildly distended and tender to palpation. The tenderness is mostly in the left lower quadrant without rebound. Femoral pulses are full and symmetric. His white blood cell count is 12,000/mm3. Which of the following is the most likely diagnosis?
Ischemia of the bowel
Pseudomembranous colitis
Invasive infectious diarrhea
Aortoenteric fistula
Perforation of the colon
A 51-year-old male with a history of alcoholic pancreatitis presented to the hospital because of sudden onset severe retrosternal and upper abdominal pain. He has been vomiting for the past few hours after consuming alcohol. His temperature is 38.1C (100.9F), blood pressure is 140/90 mm Hg, pulse is 120/min and respirations are 30/min. Examination shows palpable crepitus in the suprasternal notch. Lungs are clear to auscultation. The abdomen is tender to palpation mostly in the epigastrium. Which of the following is the most likely cause of his current condition?
Esophageal perforation
Spontaneous pneumothorax
Acute pancreatitis
Perforated duodenal ulcer
Mallory-Weiss tear
A 53-year-old male comes to the emergency department complaining of sudden onset intense, stabbing epigastric pain. He also vomited once and a dull, aching pain then spread through his entire abdomen. He has had nonspecific epigastric pain for several months and saw a physician one month ago. He also has a history of constipation, type II diabetes mellitus and hyperlipidemia. He has smoked one and a half packs of cigarettes daily for 26 years. He drinks 4 oz of alcohol daily. His temperature is 38.3C (100.4F), blood pressure is 160/95 mm Hg, pulse is 100/min and respirations are 26/min. The entire abdomen is tender to palpation with rebound, but there is no guarding. No masses are palpable, and Murphy's sign elicits mild pain. Rectal examination shows no abnormalities. Abdominal ultrasound performed 2 weeks ago showed stones in the gall bladder. Upright chest x-ray is shown below: Which of the following is the most likely diagnosis in this patient?
Untitled
Perforated peptic ulcer
Acute cholecystitis
Acute alcoholic pancreatitis
Acute gallstone pancreatitis
Perforated diverticulitis
A 39-year-old paleontologist complains of right-sided hip pain that makes it very difficult for him to lay on his right side while sleeping. He localizes the pain to the outer surface of his thigh. Which of the following is the most likely cause of his pain?
Trochanteric bursitis
Slipped femoral epiphysis
Paget's disease
Peripheral vascular disease
Hip osteoarthritis
A 34-year-old male is involved in a high-speed highway motor vehicle collision. He is intubated by rescue workers at the accident scene. In the emergency department, the patient has decreased breath sounds on the right side, normal breath sounds on the left, and hypotension. A right-sided chest tube is placed. Physical examination reveals multiple bruises over the entire chest wall as well as subcutaneous emphysema. A few hours later, his chest x-ray shows an accumulation of air in the pleural space as well as pneumomediastinum. Which of the following is the most likely diagnosis?
Bronchial rupture
Myocardial contusion
Myocardial rupture
Esophageal rupture
Diaphragmatic rupture
A 22-year-old primigravida woman at 33 weeks gestation is brought to the emergency department after a tonic clonic seizure. On arrival, she also has visual disturbances and a headache. She is given magnesium sulfate and hydralazine. She soon regains consciousness but cannot move her right arm; however, she can move her fingers. Her temperature is 37.2C (99F), blood pressure is 160/100 mm Hg, pulse is 110/min and respirations are 20/min. Examination shows her arm extended along the chest and internally rotated. There is no sensory loss on the arm, but there is an inability to externally rotate the shoulder. Deep tendon reflexes (DTR) are intact. Which of the following is the most likely cause of her inability to move her hand?
Posterior dislocation of shoulder joint
Dislocation of acromioclavicular joint
Magnesium toxicity
Anterior dislocation of shoulder joint
Todd's paralysis
A 15-year-old boy is brought to the physician because of a 15-day history of painful swelling of the right knee. The swelling and redness were immediate after hitting his knee on the door, but have not subsided after 15 days of ibuprofen. He states the pain is increasing. He has no other complaints. His temperature is 37.1C (98.9F), blood pressure is 110/75 mm Hg, pulse is 80/min, and respirations are 22/min. Laboratory studies show a normal ESR and elevated serum alkaline phosphatase. Examination shows the skin is warm and non-tender. An x-ray film of the femur and the knee joint shows an osteolytic lesion of the distal femur along with periosteal inflammation. Which of the following is the most likely diagnosis?
Osteosarcoma
Ewing's sarcoma
Chronic osteomyelitis
Osteoclastoma
Septic arthritis
A 55-year-old man comes to the physician because of chronic leg problems. He has had multiple medical problems and is unable to get good medical care due to lack of insurance. A photograph of his legs is shown below. Which of the following is the most likely cause of his condition?
Untitled
Venous hypertension
Arterial thrombosis
Arterial spasm
Peripheral neuropathy
Posterior spinal cord lesion
A 35-year-old man is brought to the emergency department after he jumped from the fourth floor of a burning building. His temperature is 36.9° C (98.5° F), blood pressure is 90/40, pulse is 90/min, and respirations are 20/min. Examination shows a fracture of the right tibia. He is conscious and his pupils are bilaterally equal and reactive to light and accommodation. His neurological examination shows paraplegia, with loss of pain and temperature in both legs but normal proprioception. Upper extremities do not show any neurological deficits. Passive straight leg raising test is negative. A CT scan of the spine shows a burst fracture at the level of the fourth thoracic vertebra. Which of the following is the most likely diagnosis?
Anterior cord syndrome
Central cord syndrome
Brown Sequard syndrome
Acute disk prolapse
Cauda equine syndrome
A 30-year-old man comes to the physician because of a 2-week history of swelling and pain in the right knee. He first experienced pain when he twisted his leg while playing football 15 days ago. He felt something popping' in the knee at that time but ignored it. The pain and swelling has been increasing since, and he feels sudden pain with extension of his leg. Examination shov1s the right knee is swollen and tender along the medial side. Full extension of the right knee is not possible due to sudden pain during terminal extension. Snapping can be felt in the right knee on tibial torsion with the knee flexed at 90 degrees. An x-ray film of the knee joint shows no abnormalities. Which of the following is the most likely diagnosis?
Medial meniscus tear
Anterior cruciate ligament injury
Posterior cruciate ligament injury
Medial collateral ligament tear
Lateral collateral ligament tear
A 25-year-old male is brought to the emergency department following a motor vehicle accident in which he was the unrestrained driver. The emergency response team's reports indicate that his breath smelled of alcohol at the scene. En route to the hospital, the patient receives 2 liters of intravenous normal saline, and in the ED his blood pressure is 100/60 mmHg, heart rate is 120/min, and respiratory rate is 34/min. His neck veins are flat. You note multiple bruises overlying his anterior chest wall and upper abdomen. On inspiration, there is inward motion of the right side of his chest wall. His abdomen is soft and non-distended. He is put on positive pressure mechanical ventilation and his chest movements become symmetric. Which of the following is the most likely diagnosis?
Flail chest
Tracheobronchial disruption
Esophageal rupture
Pneumothorax
Air embolism
A 56-year-old woman is referred to you about 3 months after a colostomy subsequent to a sigmoid resection for cancer. She complains that her stoma is not functioning properly. Which of the following is the most common serious complication of an end colostomy?
Parastomal hernia
Bleeding
Skin breakdown .
Colonic perforation during irrigation
Stomal prolapse
A 22-year-old college student notices a bulge in his right groin. It is accentuated with coughing, but is easily reducible. Which of the following hernias follows the path of the spermatic cord within the cremaster muscle?
Indirect inguinal
Femoral
Direct inguinal
Spigelian
Interparietal
An 80-year-old man with history of symptomatic cholelithiasis presents with signs and symptoms of a small-bowel obstruction. Which of the following findings would provide the most help in ascertaining the diagnosis?
Pneumobilia
Coffee-grounds aspirate from the stomach
A pH of 7.5, PCO2 of 50 kPa, and paradoxically acid urine
A palpable mass in the pelvis
A leukocyte count of 40,000/mL
A 42-year-old man has bouts of intermittent crampy abdominal pain and rectal bleeding. Colonoscopy is performed and demonstrates multiple hamartomatous polyps. The patient is successfully treated by removing as many polyps as possible with the aid of intraoperative endoscopy and polypectomy. Which of the following is the most likely diagnosis?
Peutz-Jeghers syndrome
Ulcerative colitis
Villous adenomas
Familial polyposis
Crohn colitis
A 35-year-old man is brought to the emergency department after a motorcycle accident. He is unconscious when the emergency medical team arrived. He regains consciousness on the way to the emergency department. Upon arrival, he is mildly confused and complains of headache and nausea. His temperature is 36.9° C (98.5° F), blood pressure is 102/60 mm Hg, pulse is 116/min, and respirations are 22/min. Pupils are equal and reactive to light. He moves all extremities on command, and deep tendon reflexes are symmetric. Head CT scan shows: Which of the following is the most likely diagnosis?
Untitled
Acute epidural hematoma
Acute subdural hematoma
Concussion
Diffuse axonal injury
Intracerebral bleeding
An 18-year-old woman at 9 weeks' gestation is brought to the emergency department because of an open fracture of the tibia and fibula. She is hemodynamically stabilized and referred to the orthopedic department. She is scheduled for internal fixation of the tibia for the following day. However, before the surgery she develops severe dyspnea and confusion. Her temperature is 37.7° C (99.9° F), blood pressure is 110/70 mmHg, pulse is 11 O/min, and respirations are 22/min. Examination shows numerous non-palpable petechiae in the upper part of the body. Which of the following is the most likely diagnosis?
Fat embolism
Air embolism
Amniotic fluid embolism
Thromboembolism .
Acute respiratory distress syndrome
A 46-year-old man is brought to the emergency department after a fall during a downhill bike race. He lost consciousness for approximately 1 minute after the fall. He complains of severe back and abdominal pain. He has no other medical problems. Head computed tomography (CT) scan shows no intracranial bleeding. Lumbar films suggest a compression wedge fracture of the body of L2 vertebra, and a brace is placed. Abdominal CT scan shows a small retroperitoneal bleed and splenic laceration. He is conservatively treated with analgesics and supportive measures. On hospital day three, he complains of abdominal pain and nausea. His abdomen is distended, tympanic, and mildly tender, without rebound or guarding. Bowel sounds are absent. X-ray of the abdomen reveals. Which is the most likely diagnosis?
Untitled
Paralytic ileus
Erosive gastritis
Expanding retroperitoneal hematoma
Colonic pseudoobstruction
Mesenteric ischemia
A 22-year-old man who was involved in a motor vehicle accident undergoes intravenous fluid resuscitation with 2 L normal saline over 20 minutes. He is in respiratory distress, with a respiratory rate of 40/min. He receives bilateral chest tubes. Endotracheal intubation is performed and mechanical ventilation is initiated due to progressive respiratory failure. His blood pressure is 92/50 mm Hg and pulse is 121/min. The patient is responsive to painful stimuli only. Pulmonary examination shows coarse breath sounds bilaterally. The chest x-ray is shown below. Which of the following most likely contributed to this patient's progressive respiratory failure?
Untitled
Flail chest
Diaphragmatic tear
Esophageal rupture
Pulmonary edema
Tension pneumothorax
A 48-year-old woman develops pain in the right lower quadrant while playing tennis. The pain progresses and the patient presents to the emergency room later that day with a low-grade fever, a WBC count of 13,000/mm3 and complaints of anorexia and nausea as well as persistent, sharp pain of the right lower quadrant. On examination, she is tender in the right lower quadrant with muscular spasm, and there is a suggestion of a mass effect. An ultrasound is ordered and shows an apparent mass in the abdominal wall. Which of the following is the most likely diagnosis?
Hematoma of the rectus sheath
Acute appendicitis
Cecal carcinoma
Torsion of an ovarian cyst
Cholecystitis
A 22-year-old woman presents with a painful fluctuant mass in the midline between the gluteal folds. She denies pain on rectal examination. Which of the following is the most likely diagnosis?
Pilonidal abscess
Perianal abscess
Perirectal abscess
Anal fissure
Fistula-in-ano
A 62-year-old man has been diagnosed by endoscopic biopsy as having a sigmoid colon cancer. He is otherwise healthy and presents to your office for preoperative consultation. He asks a number of questions regarding removal of a portion of his colon. Which of the following is most likely to occur after a colon resection?
Patients who undergo major colon resections suffer little long-term change in their bowel habits following operation.
Sodium, potassium, chloride, and bicarbonate will be absorbed by the colonic epithelium by an active transport process.
The remaining colon will absorb long-chain fatty acids that result from bacterial breakdown of lipids
The remaining colon will absorb less water.
The majority (> 50%) of normally formed feces will comprise solid material.
A 40-year-old female is brought to the emergency department following a motor vehicle accident in which she was the front seat passenger. She reports hitting her head against the windshield and hurting her right leg. She appears completely alert and oriented. Glasgow Coma Scale =15/15. Her pupils are equal and reactive to light. There is a bruise over the right forehead, but no tenderness is present on palpation of the cranial bones. Examination of the right leg reveals a hematoma over the thigh. Knee extension on the right is markedly reduced when compared to the left. Sensory examination reveals decreased sensory perception to both sharp and dull stimuli over the medial side of the right lower thigh and leg. All other dermatomes are intact. What nerve injury is most likely present in this patient?
Femoral nerve
Tibial nerve
Obturator nerve
Common peroneal nerve
Fibular nerve
A 28-year-old woman who is 15 weeks pregnant has new onset of nausea, vomiting, and right sided abdominal pain. She has been free of nausea since early in her first trimester. The pain has become worse over the past 6 hours. Which of the following is the most common non-obstetric surgical disease of the abdomen during pregnancy?
Appendicitis
Cholecystitis
Pancreatitis
Intestinal obstruction
Acute fatty liver of pregnancy
A 30-year-old female patient who presents with diarrhea and abdominal discomfort is found at colonoscopy to have colitis confined to the transverse and descending colon. A biopsy is performed. Which of the following is a finding consistent with this patient’s diagnosis?
Noncaseating granulomas can be expected in up to 50% of patients.
The inflammatory process is confined to the mucosa and submucosa.
Superficial as opposed to linear ulcerations can be expected.
Microabscesses within crypts are common
The inflammatory reaction is likely to be continuous.
A 62-year-old man presents with a 3-month history of an enlarged lymph node in the left neck. He is a long-time smoker of cigarettes and denies fevers, night sweats, fatigue, or cough. On physical examination there is a 1.5 cm hard, fixed mass below the angle of the mandible in the left neck. Which of the following is the most likely cause of an enlarged lymph node in the neck?
Metastatic squamous cell carcinoma
Thyroglossal duct cyst
Dermoid tumor
Carotid body tumor
Branchial cleft cyst
A 43-year-old mildly overweight female complains of periodic right knee swelling and pain with physical activity for the past three months. She says that this problem started while on a hiking trip three months ago, at which point she experienced a 'popping' sensation in her right knee. She recalls that her knee was swollen the next day, and responded to over-the-counter pain killers. Recently, she has had to limit her physical activities due to knee pain. On physical examination, there is tenderness of the anterior and medial right knee joint. Which of the following is the most likely diagnosis?
Meniscal tear
Anterior cruciate ligament tear
Osteoarthritis
Patellar tendonitis
Anserine bursitis
A 53-year-old male is brought to the emergency room after a high-speed motor vehicle accident. He was an unrestrained driver and admits to consuming a moderate amount of alcohol before driving. In the ER, he complains of bilateral chest pain and left leg pain. His past medical history is significant for emphysema, diabetes mellitus and remote drug abuse. A traumatic fracture of the left femur is evident on physical examination. His initial arterial blood gas analysis shows a pH of 7.45, p02 of 81 mmHg and pC02 of 32 mmHg. His pulmonary capillary wedge pressure is 1OmmHg. After a 2000 ml IV fluid challenge, his p02 is 76 mmHg and his pulmonary capillary wedge pressure is 12 mmHg. Chest x-ray shows alveolar opacities over the right and left lower lobes. Hours after the accident, he complains of continued chest pain and shortness of breath. Which of the following diagnoses is most likely responsible for his shortness of breath?
Pulmonary contusion
Aspiration pneumonia
Hemothorax
Myocardial contusion
Aortic rupture
A 23-year-old woman comes to the physician because of right-sided foot pain. The pain started 5 weeks ago and is sharp and localized to the forefoot. She recalls no trauma or other inciting event but is an avid runner training for a long-distance race. The pain has been worsening over the past 1 week and prevents her from doing her daily running activities. She takes no medications. She is a vegetarian and does not drink soda. She does not use tobacco, alcohol, or illicit drugs. She is not sexually active, and her last menstrual period was 8 weeks ago. Her temperature is 37°C (98.6°F), blood pressure is 100/60 mm Hg, pulse is 68/min, and respirations are 12/min. Her body mass index is 15 kg/m2. Examination reveals tenderness to palpation along the first four metatarsal bones on the dorsal surface of the right foot, normal range of motion, and no erythema or bruising. Which of the following is the most likely diagnosis?
Stress fracture
Morton neuroma
Plantar fasciitis .
Tarsal tunnel syndrome
Tenosynovitis
An ultrasound is performed on a patient with right upper quadrant pain. It demonstrates a large gallstone in the cystic duct but also a polypoid mass in the fundus. Which of the following is an indication for cholecystectomy for a polypoid gallbladder lesion?
Presence of clinical symptoms
Size greater than 0.5 cm
Patient age of older than 25 years
Presence of multiple small lesions
Absence of shadowing on ultrasound
An alcoholic man has been suffering excruciating pain from chronic pancreatitis recalcitrant to analgesics and splanchnic block. A surgeon recommends total pancreatectomy. A patient who has a total pancreatectomy might be expected to develop which of the following complications?
Diabetes mellitus and steatorrhea
Diabetes mellitus and constipation
Hypoglycemia and steatorrhea
Hypoglycemia and constipation
Hypoglycemia
A 36-year-old man who was hit by a car presents to the ER with hypotension. On examination, he has tenderness and bruising over his left lateral chest below the nipple. An ultrasound examination is performed and reveals free fluid in the abdomen. What is the most likely organ to have been injured in this patient?
Spleen
Liver
Kidney
Intestine
Pancreas
A 30-year-old man is stabbed in the arm. There is no evidence of vascular injury, but he cannot flex his three radial digits. Which of the following structures has he most likely injured?
Median nerve
Thenar and digital nerves at the wrist
Flexor pollicis longus and flexor digitus medius tendons
Radial nerve
Ulnar nerve
A 70-year-old man presents to the ER with several fractures and a ruptured spleen after falling 20 ft. Which of the following will occur in response to the injury?
Hepatic synthesis of acute-phase reactants
Decreased glutamine consumption by fibroblasts, lymphocytes, and intestinal epithelial cells
Decreased urinary nitrogen loss
Inhibition of skeletal muscle breakdown by interleukin 1 and tumor necrosis factor (TNF, cachectin)
Decreased liver gluconeogenesis
A 62-year-old woman is seen after a 3-day history of fever, abdominal pain, nausea, and anorexia. She has not urinated for 24 hours. She has a history of previous abdominal surgery for inflammatory bowel disease. Her blood pressure is 85/64 mm Hg, and her pulse is 136. Her response to this physiologic state includes which of the following?
Hyperkalemia
Increase in sodium and water excretion .
Increase in renal perfusion
Decrease in cortisol levels
Hypoglycemia
A 46-year-old man is brought to the emergency department after being involved in a motor vehicle collision. He is unresponsive and his injuries include a basilar skull fracture, brain contusion, fractures of ribs 7-10, hemopneumothorax on the right, and a pelvic fracture. After placement of a chest tube and pelvis fixation, his condition stabilizes. On the fifth day of his hospital stay, he is still unresponsive with a Glasgow Coma Scale of 8 and spontaneous respirations. Examination shows an abnormal facial reaction with palpation of the right upper quadrant of the abdomen and diminished bowel sounds. Rectal examination shows no abnormalities. Nasogastric tube aspiration shows retention of gastric contents. An abdominal CT scan shows gaseous distention of the small and large bowels without air-fluid levels. The gall bladder is distended with pericholecystic fluid but no gallstones. Which of the following is the most likely diagnosis for this patient's abdominal findings?
Cholecystitis
Bowel obstruction
Pancreatitis .
Mesenteric ischemia
Lung contusion
An 18-year-old woman presents with abdominal pain, fever, and leukocytosis. With the presumptive diagnosis of appendicitis, a right lower quadrant (McBurney) incision is made and a lesion 60 cm proximal to the ileocecal valve is identified (see photo). Which of the following is the most likely diagnosis?
Untitled
Meckel diverticulum
Intestinal duplication
Mesenteric cyst
Ileoileal intussusception
Christmas tree” type of ileal atresia
A newborn infant born from a mother with polyhydramnios presents with excessive salivation along with coughing and choking with the first oral feeding. An xray of the abdomen shows gas in stomach and a nasogastric tube coiled in the esophagus. Which of the following is the most likely diagnosis?
Esophageal atresia and tracheoesophageal fistula (TEF)
Esophageal atresia
Tracheoesophageal fistula
Omphalocele
Gastroschisis
A 2-week-old infant presents with sudden onset of bilious emesis. Plain films of the abdomen show evidence of an intestinal obstruction. An upper gastrointestinal (UGI) contrast series reveals a midgut volvulus with the site of obstruction at the third portion of the duodenum. Which of the following is the most likely diagnosis?
Anomalies of intestinal rotation and fixation
Necrotizing enterocolitis (NEC)
Hirschsprung disease
Hypertrophic pyloric stenosis
Intussusception .
A 65-year-old woman is involved in a motor vehicle collision and sustains multiple left-sided rib fractures. Upon presentation to the ER her vital signs are stable and she is in no respiratory distress. Chest x-ray reveals fractures of ribs 4 to 7 on the left side without evidence of hemothorax or pneumothorax. She is admitted for observation and a few hours later she develops shortness of breath. A repeat chest x-ray demonstrates a well-defined infiltrate in her left lung. What is the most likely diagnosis?
Pulmonary contusion
Pulmonary embolus
Pneumonia
Myocardial infarction
Cardiac tamponade
Following a head-on motor vehicle collision, a 21-year-old unrestrained passenger presents to the ER with dyspnea and respiratory distress. She is intubated and physical examination reveals subcutaneous emphysema and decreased breath sounds. Chest x-ray reveals cervical emphysema, pneumomediastinum, and a right-sided pneumothorax. What is the most likely diagnosis?
Tracheobronchial injury
Tension pneumothorax
Open pneumothorax .
Esophageal injury
Pulmonary contusion
A 35-week-term infant presents with cyanosis shortly after birth. His arterial oxygen saturation is only 30%. Which of the following is the most likely diagnosis?
Transposition of the great vessels
Patent ductus arteriosus
Coarctation of the aorta
Atrial septal defect
Ventricular septal defect
A 22-year-old primi-gravida woman is brought to the emergency department during the 33rd week of pregnancy after a tonic-clonic seizure. She has no history of seizure disorder and has not had any complications during her pregnancy. She is given magnesium sulfate and hydralazine. One hour later, she is lethargic and complains of persistent blurry vision and headache. She also complains of muscle pain, sore joints, and inability to move her right arm. Her temperature is 37.2°C (99°F), blood pressure is 182/111 mm Hg, pulse is 112/min, and respirations are 16/min. She holds her right arm adducted and internally rotated. Examination shows no sensory loss but an inability to externally rotate the right arm. Deep tendon reflexes (DTRs) are intact bilaterally, and handgrip is preserved on both sides. Which of the following is the most likely cause of her arm weakness?
Posterior shoulder dislocation
Anterior shoulder dislocation
Magnesium toxicity
Postictal (Todd) paralysis
Radial nerve compression
A 78-year-old diabetic man has undergone surgical repair of a large abdominal aortic aneurysm. Postoperatively, he develops left lower quadrant abdominal pain followed by bloody diarrhea. He has a history of prostate cancer and received radiation therapy several years ago. He eats a low fiber diet. He quit smoking recently. Vital signs show a low grade fever. Examination shows tenderness in the left lower quadrant and rectal examination reveals blood in the stool. CT scan of the abdomen demonstrates thickening of the colon at the recto-sigmoid junction. On colonoscopy, ulcerations are seen in the same area while the colon above and below the lesions is completely normal. Which of the following is the most likely cause of his symptoms?
Ischemic colitis
Acute diverticulitis
Radiation proctitis
Clostridium difficile colitis
Inflammatory bowel disease
A 55-year-old man comes to the physician because of a 4-month history of an ulcer on the sole of his right foot. He has had no trauma and does not remember how he got the ulcer. He states the ulcer has been difficult to heal and readily gets infected. He has multiple medical problems. He does not use tobacco, alcohol or drugs. Examination shows the ulcer is located on the sole of his foot just below the head of the first metatarsal bone. His foot is warm and dry and appears slightly deformed. Dorsalis pedis pulses are present. Which of the following is the most likely cause of his condition?
Peripheral neuropathy
Venous hypertension
Arterial spasm
Central spinal cord lesion
Posterior spinal cord lesion
A 43-year-old male complains of right shoulder pain and weakness after falling on his outstretched hands two days ago. He denies shoulder deformity. The physician passively abducts both his arms above his head and then asks him to bring his arms down slowly in an adducting motion. The right arm drops rapidly at the midpoint of its descent. What is the most likely diagnosis?
Rotator cuff tear
Biceps tendon tear
Long thoracic nerve injury
Lower brachial trunk injury
Humeral neck fracture
A 45-year-old policeman presents to your office complaining of tiredness and sleepiness. He says that his job seems tiring to him recently. It is difficult for him to get up in the morning and go to work. He goes to bed early because he feels tired and sleepy. Two months ago, he was investigating a case of mass murder. He slipped on the blood on the floor, fell and hit his head. He also describes recent abdominal pain that is constant and gnawing, interfering with his sleep. His appetite is poor, and he lost 15 pounds over the last month. Physical examination is significant only for tenderness and fullness in the epigastrium. Which of the following is the most likely diagnosis?
Pancreatic cancer
Duodenal ulcer
Major depressive episode
Post-traumatic stress disorder
Chronic subdural hematoma
A 32-year-old man comes to the emergency room (ER) because of acute onset left flank pain, hematuria and vomiting. His pain is relieved with analgesics in the ER. He has a history of abdominal pain due to Crohn disease, but that pain was always in the right lower quadrant and was never this severe. His temperature is 36.8°C (98.2°F), blood pressure is 120/65 mm Hg, pulse is 110/min and respirations are 16/min. Chest auscultation is clear. Abdomen is soft and mildly tender over the left flank. He has no rebound or rigidity. Bowel sounds are decreased. A laparotomy scar is present in right lower quadrant. Which of the following is the most likely cause of his symptoms?
Increased absorption of oxalate
Increased recycling of bile salts and fatty acids
Increased absorption of calcium
Recurrent bacterial infection in the kidney
Increased parathyroid hormone activity
A 36-year-old male presents with firm, non-tender swelling of his right cheek. He tells you that he had similar swelling at that site two years ago and was diagnosed with a tumor, which was subsequently removed without complication. Examination reveals fullness of the pre-auricular space on the right side. Repeat surgery in this patient is most likely to result in which of the following complications?
Facial droop
Hoarseness
Tic douloureux
Tongue palsy
Jaw asymmetry
A 39-year-old paleontologist complains of right-sided hip pain that makes it very difficult for him to lie on his right side while sleeping. He localizes the pain to the outer surface of his thigh. He was recently diagnosed with hypertension and hyperlipidemia. He takes hydrochlorothiazide and atorvastatin. He has smoked one pack of cigarettes daily for 15 years. He does not use alcohol or illicit drugs. Which of the following is the most likely cause of his pain?
Trochanteric bursitis
Slipped femoral epiphysis
Paget's disease
Peripheral vascular disease
Hip osteoarthritis
A 65-year-old male is being evaluated for hip pain. The pain has been present for several months and is constant. He denies any weight loss or loss of appetite. His past medical history is significant only for high blood pressure. His temperature is 37.2°C (98.9°F), blood pressure is 150/88 mm Hg, pulse is 80/min and respirations are 12/min. Physical examination is unremarkable. Laboratory studies show: Alkaline phosphatase Elevated, Gamma glutamyl transferase Normal, Serum calcium Normal, 25, (OH)2 vitamin D Normal. Bone scan shows increased uptake in several spots. This patient is at the highest risk of developing?
Hearing loss
Subarachnoid hemorrhage
Renal cell carcinoma
Pulmonary hemorrhage
Carpal tunnel syndrome
A 25-year-old motorcyclist is brought to the emergency department after being involved in a collision with an automobile. On arrival he is in obvious pain. He expresses an urge to void, but is unable to do so. Genital examination shows blood at the urethral meatus and a scrotal hematoma. Rectal examination reveals a high-riding prostate. Abdominal examination is suggestive of a distended bladder. Which of the following is the most likely diagnosis?
Urethral injury
Intraperitoneal bladder rupture
Extraperitoneal bladder injury
Fracture of penis
Renal injury
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