Immuno exam III
Immunology Insights: Passive Transfer Quiz
Test your knowledge on the intricacies of immunoglobulin transfer and neonatal immunity with our engaging quiz! This assessment covers essential topics such as passive immunity, maternal antibody transfer, and the impact of infectious diseases on fetal development.
Whether you're a veterinary student, a practicing professional, or just interested in immunology, this quiz is designed for you. Here are some of the key topics you'll explore:
- Passive transfer mechanisms
- Colostrum absorption in neonates
- Effects of disease on fetal immune development
- Differences in placentation among species
During passive transfer of immunoglobulins from mother to neonate, early absorption during the first 24 hours after birth is crucial. What is the reason for this urgency?
The neonate is most susceptible to infection during this time
The mother only produces vital antibodies for the first 24 hours after parturition
Best antibody absorption in the neonate occurs during the first 24 hours of life via gut absorption, after 24 hours, "gut closure" occurs
The neonate will suckle the most volume during its first 24 hours of life
Which of the following could result after contraction of a disease in the early fetus (1st trimester)?
Nothing, early contraction gives the fetus the best chance for survival
Early contraction will allow the fetus to be born with antibodies from the contracted antigen
The fetus will develop immune tolerance to the contracted antigen, once born will have persistent infection.
The fetus will be born with severe malformations, but be immune to the contracted antigen
Which one of these statements explain absorption of colostral antibodies?
Neonatal GI tract has low proteolytic activity
Presence of trypsin inhibitors in colostrum
Specialized gut epithelial cells
None of the above
All of the above
IgG's are transferred from dams to neonates through which method?
Colostrum
Colostrum and placenta
Placenta
Placenta and maternal secretions
None of the above
You are teaching a seminar about natural vs artificial immunity. As you discuss transplacental immunity, it seems like lots of students are confused why horses, cows, pigs, and sheep have a different outcome than the dog and cat. What is the best statement to clear up this confusion?
Dogs and cats have hemochorial placentation, which transfers IgM across the placenta. Horse, cows, pigs, and sheep have epitheliochorial placentation which results in the transfer of IgG across the placenta.
Dogs and cats have hemochorial placentation, which transfers IgG across the placenta. Horse, cows, pigs, and sheep have epitheliochorial placentation which results in the transfer of IgG across the placenta
Dogs and cats have endotheliochorial placentation, which transfers IgG across the placenta. Horse, cows, pigs, and sheep have epitheliochorial placentation which results in the transfer of IgG across the placenta.
Dogs and cats have endotheliochorial placentation, which transfers IgG across the placenta. Horse, cows, pigs, and sheep have epitheliochorial placentation which results in no transfer of antibodies.
Dogs and cats have epitheliochorial placentation, which transfers IgG across the placenta. Horse, cows, pigs, and sheep have epitheliochorial placentation which results in transfer of IgM across colostrum.
Candice, is a poor cow with mastitis who just gave birth to multiple calfs. You are worried about failure of passive transfer (FPT) which results in _____________________________. You know FPT Treatment is time sensitive. How would you plan treatment for failure of passive transfer (FPT)?
Inadequate transfer of acquired immunoglobulin to the neonate Treat with IV serum or plasma in the first 24 hours Treat with oral colostrum after 24 hours
Inadequate transfer of plasma proteins to the neonate Treat with oral colostrum in the first 24 hours Treat with IV serum or plasma after 24 hours
Inadequate transfer of colostral immunoglobulin to the neonate; Treat with oral colostrum in the first 24 hours Treat with IV serum or plasma after 24 hours
Inadequate transfer of transplacental immunoglobulin to the neonate Treat with IV serum or plasma in the first 24 hours Treat with oral colostrum after 24 hours
Inadequate transfer of artificial immunoglobulins to the neonate Treat with IV serum or plasma in the first 24 hours Treat with oral colostrum after 24 hours
A pregnant cow is brought to your clinic and is diagnosed with Bovine Viral Diarrhea Virus. Which of the following results of in utero infection of cytopathic BVDV would you not see?
Abortion
Malformations
Normal
Tolerance
Mummification
After a mare has given birth, it is important for her foal to feed within the first 6 hours and take in her colostrum. Which of the following are an explanation as to why it is important to take in colostrum so quickly?
Colostrum is not produced after 6 hours
FcR receptors needed for antibody uptake begin to become replaced with epithelium
The neonatal immune system is non-functional for 6 hours after birth
The mother will reject the foal if it does not feed
Horses do not have colostral antibodies
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