Neuro Navigator Quiz
Which of the main structures of the brain is responsible for balance and coordination?
Cerebrum
Brainstem
Cerebellum
Vertebral arteries
Which of the following is NOT one of the four lobes of the brain?
Frontal lobe
Parietal lobe
Temporal lobe
Glial lobe
Which of the four lobes controls personality and high-order functioning?
Frontal lobe
Parietal lobe
Temporal lobe
Occipital lobe
Which of the four lobes controls visual and tactile perception?
Parietal lobe
Frontal lobe
Occipital lobe
Temporal lobe
Which of the following properly defines the blood-brain barrier?
3 membranes that cover the brain and spinal cord
Connected cavities that contain CSF
System of arteries that supply blood to the brain
Tight junction among cells of the brain capillaries that selectively allows substances to cross neuronal membranes
Which type of glial cell produces myelin, a fatty substance that surrounds and insulates the nerve axon of the brain and spinal cord?
Astrocytes
Oligodendrocytes
Ependymal cells
Meninges
Heart rate, blood pressure, breathing, swallowing, level of alertness, and vomiting are all controlled by:
Cerebellum
Hypothalamus
Temporal lobe
Brainstem
A tumor within the cervical area of the spinal cord could lead to loss of function in which areas of the body?
Hip to toes
Chest to umbilicus
Neck, arms, and hands
Hands and toes
What is the main function of CSF?
Serve as a cartilage pad between vertebrae
Bathe and cushion the spinal cord
Supply blood to the spinal cord
Control motor function of the body from the neck to the toes
Select all that apply: Which of the following is TRUE about EGFR?
EGFR stands for Epidermal Growth Factor Receptor
EGFR is amplified in approximately 50% of glioblastomas
Amplification is associated with better prognosis
Amplification is associated with poor prognosis
All of the following are measured in a diagnostic lumbar puncture except:
Cell count and differential
Tumor size
Glucose level
Tumor markers
MGMT (methyl guanine methyl transferase) status is the primary determinant of
Benefit of alkylating agent chemotherapy
Risk of side effects with treatment
Seizure risk
Type of biopsy needed
Each of the following is a type of brain biopsy except:
Needle biopsy
Closed biopsy
Stereotactic biopsy
Open biopsy
The most malignant tumors - those that reproduce rapidly and have a bizarre appearance under the microscope - would be classified as which of the following?
Grade I
Grade II
Grade III
Grade IV
Which of the following is untrue about astrocytomas?
Astrocytomas arise from star-shaped cells that make up the supportive tissue of the brain
Most astrocytomas in adults are high grade
Astroccytomas are graded on a scale from I-IV
Most astrocytomas in children are high grade
There are two types of Grade IV glioblastomas: primary, or 'de novo', and secondary. Which is untrue of primary tumors?
They are very aggressive and the most common form of grade IV glioblastoma
They originate as a lower grade tumor and then evolve into a grade IV tumor
They are actually a grade III tumor
They are always curable with surgery
Mutations in which gene are found in 70-80% of all low-grade gliomas in adults?
MGMT
Chromosome 1
IDH gene
CEA
Optune treatment for primary and recurrent glioblastomas utilizes:
Electrical current
Musical therapy
Inactivated viruses
A specialized series of head movements
Which of the following treatment types is considered the first treatment step for all grades of astrocytoma?
Chemotherapy
Surgery
Radiation
Immunotherapy
Which of the following statements about stereotactic is UNTRUE?
It is the method of tissue diagnosis used when the tumor is difficult to access
It is the method of tissue diagnosis used when the patient is a poor surgical candidate due to comorbidities
Not the preferred method, as sampling error may be possible due to a small tissue sample
It is the preferred method for tissue sampling and is considered the primary treatment modality
Spinal surgical resection is utilized for extradural tumors of the spine for all of the following reasons except:
If the tumor is not radiosensitive
If patient's neurologic status is deteriorating
If the patient has multiple comorbidities that make him/her a poor surgical candidate
If the tumor type is not known
Ventriculoperitoneal (VP) shunt is placed for the management of:
Hydrocephalus
Chemotherapy administration
Assistance with radiation treatment
Prevention of toxicities
Ommaya reservoir is placed for the
Management of hydrocephalus
Management of radiation therapy dose
Delivery of intrathecal chemotherapy
Relief of pressure within the CNS
Radiation therapy is commonly used in the treatment of neurological tumors. EBRT stands for:
Entire Beam Radiation Therapy
Extra Beam Radiation Therapy
Exacting Beam Radiation Therapy
External Beam Radiation Therapy
Which of the following is NOT a symptom of global toxicities caused by radiation therapy for neurologic cancers?
Headache
Vomiting
Somnolence
Neurocognitive changes
Late radiation effects (occurring more than 6 months to several years following radiotherapy) include all of the following EXCEPT:
Optic nerve toxicities
Diffuse white matter changes
Secondary malignancies (risk greatest with cranial radiation given to young children)
Cardiovascular toxicities
All of the following statements are true about temozolomide (Temodar) administration for first-time glioma treatment EXCEPT:
It is able to permeate the blood-brain barrier
Myelosuppression is minimal and noncumulative
In combination with radiation therapy, it is the standard of care in the treatment of high-grade gliomas
It is an IV administered platinum drug
If a patient with CNS lymphoma receives a positive eye exam, which of the following should be considered?
Stopping treatment - the patient is cured
Intraocular chemotherapy
Surgical intervention
Ocular radiation
Which of the following is NOT a type of immunotherapy?
Glucocorticoids
Monoclonal antibodies
Vaccines
Immunotoxins
The benefits of Gamma Knife include all of the following EXCEPT:
It is bloodless and virtually painless
It usually does not result in hair loss
It is directed to targeted areas and prevents treatment of adjacent, normal brain tissue
The patient is under conscious sedation for the procedure
Which of the following is a treatment utilizing focused heat therapy (48-52 degrees Celsius) to the tumor while sparing surrounding healthy tissue?
Gene therapy
Stereotactic Laser Ablation
Siteman's Technique
Thermoregulation Knife
Which of the following is NOT a vaccine type featured in continued, promising research on vaccine therapy for malignant gliomas?
Dendritic cell vaccines
Heat shock protein vaccines
Glial vaccines
Peptide vaccines
Common early symptoms of astrocytoma include all of the following EXCEPT:
Headache
Changes in behavior
Vision loss
Seizures
High doses of which of the following medications can be used to manage acute cerebral edema?
Keppra
Dilantin
Glucocorticoids
Demerol
Which of the following is NOT an oncologic emergency associated with neurologic tumors?
Seizure
CSF leak
Increased intracranial pressure
Somnolence
Which of the following is considered a common Quality of Life (CQL) issue for patients with neurologic tumors?
Sleep disturbance
GERD
New-onset diabetes
Leg cramps
Pituitary tumors cause symptoms in three distinct ways. Which of the following is NOT one of the three?
Producing too much of one or more hormones
Causing balance and coordination disturbances
Causing the pituitary gland to make too little of one or more hormones
Pressing on the optic nerves, causing visual disturbances
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