Olfori pq
Test Your Gastrointestinal Pharmacology Knowledge
Welcome to our pharmacology quiz, where we dive deep into various gastrointestinal medications and their mechanisms of action. Test your knowledge about PPIs, prokinetic agents, and antihistamines!
Prepare to challenge yourself with questions on:
- Drug classifications
- Mechanism of action
- Pharmacological properties
Omeprazole is a PPI, which of the following is true?
Omeprazole is a prodrug
Esomeprazole is the methyl analog of omeprazole
Activation of omperazole involves the generation of a sulfenamide intermediate
Metoclopramide (Reglan®) is a prokinetic agent that belongs to which of the following chemical class(es)?
Anti-emetics
Benzamide derivatives
Benzimidazole
Salicylate
3. Which of the following antispasmodic agents contains a tropane ring system?
Dicyclomine
Mebeverine
Hyoscyamine
Glycopyrolate
Which of the following preparations contains simethicone (anti-bloating agent)?
Milk of magnesia
Alka seltzer
Mylanta
Amphojel
Tums
Which of the compounds is an antihistamine
X
Y
Z
X and Y
X, Y, Z
6. Which of the following statements is/are true about the compounds X-Z? Select all that apply
A) Compound X is a precursor for the biosynthesis of compound Y.
B) Compound Y is a precursor for the biosynthesis of compound X.
C) Compound Z directly inhibits the biological activity of compound Y.
D) Compound X exists as two tautomeric structures in aqueous solution.
The methyl group substitution on the imidazole ring of compound Z
A) imparts H1 receptor selectivity
B) reduces binding to the proton pump
C) imparts H2 receptor selectivity
D) increases its aqueous solubility
E) introduces a stereocenter
Methylnaltrexone hydrochloride is a quartenary ammonium salt.
True
False
Which of the following is a morphine analog used in treating Opioid-Induced Constipation (OIC)?
Lubiprostone (Amitiza)
Ricinoleic acid
Bisacodyl
Methylnaltrexone
Linzess
Cimetidine (Tagemet) is known to inhibit the cytochrome P450 enzyme system. Which of the following structural elements has been shown to be responsible for this effect?
Imidazole ring
Sulfur atom
Cyano group
Methyl-cyano-guanidine
Nitrogen atom
The H2 antagonists used for PUD are susceptible to sulfoxidation because they contain S in the structures
True
False
Pantoprazole is a prodrug that relies on an acidic environment in the parietal cells to be actived
True
False
Esomeprazole is the R-enantiomer of Omeprazole
True
False
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