colloquim 2

class 1a antiarrythmic
proclamide
lidocaine
ethacizine
flecainide
class 1b antiarrythmic
proclamide
lidocaine
ethacizine
flecainide
class 1c antiarrythmic
proclamide
lidocaine
ethacizine
flecainide
propafenon
class 2 antiarrythmic
proclamide
lidocaine
ethacizine
flecainide
propafenon
beta blockers
class 4 antiarrythmic
calcium channel blockers
sotalol
ethacizine
flecainide
vernakalant
beta blockers
class 3 antiarrhythmic
calcium channel blockers
sotalol
amoidarone
flecainide
vernakalant
beta blockers
NOT indicated in ventricular arrythmias
calcium channel blockers
sotalol
amoidarone
flecainide
vernakalant
beta blockers
NOT indicated in supra-ventricular arrythmias
lidocaine
sotalol
amoidarone
magnesium sulfate
vernakalant
beta blockers
non-classified antiarrhythmic agents
atropine
magnesium sulfate
amoidarone
flecainide
epinephrine
digoxin
class 1a antiarrhythmic agents SE
hypotension
torsade de pointes
lupus erythematodes syndrome
CNS toxicity (seizures)
class 1b antiarrhythmic agents SE
hypotension
torsade de pointes
heart failure
CNS toxicity (seizures)
class 1c antiarrhythmic agents SE
hypotension
torsade de pointes
heart failure
CNS toxicity (seizures)
amiodarone SE
hypothyroidism
hepatotoxicity
pneumofibrosis
CNS toxicity (seizures)
blue skin
phototoxicity
vernakalant SE
hypothyroidism
bradicardia
pneumofibrosis
CNS toxicity (seizures)
hypotension
phototoxicity
what antiarrhythmic drugs inhibit only NA+ influx in contractile myocardium phase 0
class 1a
class 1b
class 1c
class 2
class 3
class 4
what antiarrhythmic drugs inhibit only k+ influx in contractile myocardium phase 3
class 1a
class 1b
class 1c
class 2
class 3
class 4
what antiarrhythmic drugs inhibit k+ influx in contractile myocardium phase 3 and NA+ in phase 0
class 1a
class 1b
class 1c
class 2
class 3
class 4
what antiarrhythmic drugs inhibit Ca+ influx in SA and AV phases 0 and 4
class 1a
class 1b
class 1c
class 2
class 3
class 4
ACE inhibitors
enalapril
captopril
valsartan
verapamil
ARB
enalapril
captopril
valsartan
verapamil
osmotic diuretics
mannitol
acetazolamide
furosemide
indapamide
carbonic anhydrase inhibitors
mannitol
acetazolamide
furosemide
indapamide
loop diuretics
mannitol
torasamide
furosemide
indapamide
thiazide and thiazide like diuretics
acetazolomide
torasamide
hydrochlorothiazide
indapamide
mineralcorticoid receptor antagonist
spironolactone
torasamide
hydrochlorothiazide
indapamide
eplerenone
furosemide
mannitol SE
dehydration
electrolyte imbalance
metabolic acidosis
ototoxicity
acetazolamide SE
dehydration
electrolyte imbalance
metabolic acidosis
ototoxicity
loop diuretics SE
hypokalemia
hyperkalemia
hypocalcaemia
ototoxicity
mechanism of action of Osmotic diuretics
Proximal tubules, Loop of Henle Osmotically induced water excretion
Proximal tubules Carbonic anhydrase inhibition
Ascending part of Loop of Henle Inhibition of Na+/K+/2Cl- transporter
Distal tubules Na+/Cl- transporter inhibition
Collection ducts Aldosterone receptor blockade
mechanism of action of loop diuretics
Proximal tubules, Loop of Henle Osmotically induced water excretion
Proximal tubules Carbonic anhydrase inhibition
Ascending part of Loop of Henle Inhibition of Na+/K+/2Cl- transporter
Distal tubules Na+/Cl- transporter inhibition
Collection ducts Aldosterone receptor blockade
mechanism of action of carbonicanhydrase inhibitors
Proximal tubules, Loop of Henle Osmotically induced water excretion
Proximal tubules Carbonic anhydrase inhibition
Ascending part of Loop of Henle Inhibition of Na+/K+/2Cl- transporter
Distal tubules Na+/Cl- transporter inhibition
Collection ducts Aldosterone receptor blockade
mechanism of action of thiazide/thiazide-like diuretics
Proximal tubules, Loop of Henle Osmotically induced water excretion
Proximal tubules Carbonic anhydrase inhibition
Ascending part of Loop of Henle Inhibition of Na+/K+/2Cl- transporter
Distal tubules Na+/Cl- transporter inhibition
Collection ducts Aldosterone receptor blockade
mechanism of action of mineralocorticoid receptor agonist
Proximal tubules, Loop of Henle Osmotically induced water excretion
Proximal tubules Carbonic anhydrase inhibition
Ascending part of Loop of Henle Inhibition of Na+/K+/2Cl- transporter
Distal tubules Na+/Cl- transporter inhibition
Collection ducts Aldosterone receptor blockade
antiplatelet GP IIb / IIIa receptor inhibition by:
Tirofiban
Clopidogrel
Ticagrelor
Acetylsalicylic acid
antiplatelet P2Y12 receptor antagonist:
Tirofiban
Clopidogrel
Ticagrelor
Acetylsalicylic acid
antiplatelet cox 1 inhibition:
Tirofiban
Clopidogrel
Ticagrelor
Acetylsalicylic acid
anticoagulants low molecular weight heparin:
warfarin
Clopidogrel
fondaparinux
enoxaparin
Selective direct inhibitors of factor IIa
dabigatran
Clopidogrel
fondaparinux
warfarin
Selective direct inhibitors of factor Xa
apixaban
rivaroxaban
fondaparinux
enoxaparin
Selective indirect inhibitors of factor Xa
apixaban
rivaroxaban
fondaparinux
enoxaparin
Antithrombotic agents
apixaban
heparin
alteplase
enoxaparin
Zymogen synthesis inhibitors: Vitamin K antagonists
apixaban
heparin
warfarin
enoxaparin
Antihemorrhagic (hemostatic) agents Fibrinolysis inhibitor
apixaban
desmopressin
tranexamic acid
enoxaparin
Antihemorrhagic (hemostatic) agents Vasopressin receptor agonists
apixaban
desmopressin
tranexamic acid
fondaparinux
second generation beta blockers cause vasodilatation
true
false
Methyldopa indication
gestational hypertension
acute hypotension
metabolic syndrome
hypertensive emergencies
Sodium nitroprusside indication
gestational hypertension
acute hypotension
metabolic syndrome
hypertensive emergencies
Centrally acting antihypertensive agents induce vasodilation without inducing reflex tachycardia
true
false
antianginal medications Hypolipidemic agents
Atorvastatin
Tirofiban
Ezetimibs
Evolocumab
Fenofibrate
Ticagrelor
Calcium channel blockers Dihydropyridine
Nifedipine
Amlodipine
Verapamil
Diltiazem
Calcium channel blockers Non-dihydropyridine
Nifedipine
Amlodipine
Verapamil
Diltiazem
Sinus Node Inhibitors
Nifedipine
Ranolazine
Ivabradine
Diltiazem
Late sodium flow inhibitors
Nifedipine
Ranolazine
Ivabradine
Diltiazem
Digoxin SE
rhythm disorders
ototoxicity
hypokalaemia,
hypocalcaemia,
Dobutamine mechanism of action
Beta 1 adrenoreceptor agonist
Dopaminergic D1 receptor, adrenergic beta 1, alpha 1 receptor agonist.
morphine is used to decrease tachypnoea
true
false
drugs used to treat ACS
aspirin
tirofiban
ticagrelor
clopidogrel
heparin
fondaparinux
alteplase
enoxaparin
dabigatran
rivaroxaban
warfarin
drugs used to treat stroke
aspirin
tirofiban
ticagrelor
clopidogrel
heparin
fondaparinux
alteplase
enoxaparin
dabigatran
rivaroxaban
warfarin
drugs used to DVT/PE
aspirin
tirofiban
ticagrelor
clopidogrel
heparin
fondaparinux
alteplase
enoxaparin
dabigatran
rivaroxaban
warfarin
widens QRS and increases qt interval
class 1a
class 1b
class 1c
shortens qt interval
class 1a
class 1b
class 1c
widens qrs only
class 1a
class 1b
class 1c
fast dissociation kinetics of drugs in NA+ channels
class 1a
class 1b
class 1c
slow dissociation kinetics of drugs in NA+ channels
class 1a
class 1b
class 1c
medium dissociation kinetics of drugs in NA+ channels
class 1a
class 1b
class 1c
drug affinity in NA+ channels: open>inactivated
class 1a
class 1b
class 1c
drug affinity in NA+ channels: inactivated>open
class 1a
class 1b
class 1c
amiodarone antidotes
sodium bicarbonate
magnesium
calcium
potasium
0
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