CC1 LEC
Rich source of energy and an efficient way for the body to store excess calories
Cholesterol
Phospolipids
Fatty acids
Lipids
Linear chains of C-H bonds that terminate with a carboxyl group
Triglyceride
Fatty acids
Phospolipids
Cholesterol
Fatty acids are measured with its constituent forms
True
False
What are the constituent form of Fatty acids?
Lipoproteins
Lipids
Triacylglycerol
Cholesterol
Phospolipids
INCREASED TAG
Malabsorption syndrome
Hyperlipoproteinemia types I, IIb, III, IV, V
Alcoholism
Hyperthyroidism
Hyporthyroidism
Pacreatitis
Brain infarction
Nephrotic syndrome
DECREASED TAG
Malabsorption syndrome
Hyperlipoproteinemia types I, IIb, III, IV, V
Hyperthyroidism
Hyporthyroidism
Alcolism
Pancreatitis
Brain infarction
Nephrotic syndrome
Contains two esterified fatty acids molecule attached to 1 molecule by ester bonds
Phospolipids
Triglycerides
Cholesterol
Lipids
Two esterified fatty acids and a phosphorylated glycerol
Phospolipids `
Triglyceride
Cholesterol
Lipids
Cholesterol that contains 4 rings
Chenodeoxycholic acid
Steroids
Cyclipentanoperhydrophenanthrene
Cyclopentaneglyceride
Main protein on HDL
Apolipoprotein
Apo B
Apo A-1
Apo B-100
Transporters of cholesterol and triglycerides
Lipids
Cholesterol
Phospolipids
Lipoprotein
Protein
Smallest but most dense lipoproteins particle
HDL
LDL
VLDL
Chylomicrons
The largest but least dense of the lipoprotein particles
HDL
LDL
VLDL
Chylomicrons
Major carriers of endogenous triglycerides and transfer triglycerides from the liver to peripheral tissue
HDL
LDL
VLDL
Chylomicrons
LDL is also known as?
Alpha lipoprotein
Beta lipoprotein
Gamma Lipoprotein
Delta Lipoprotein
Lipoprotein X is found in patients with?
Obstructive jaundice
Prehepatic jaundice
LCAT defieciency
Anderson's disease
Autosomal recessive disorder that has defective Apo B synthesis
Abetalipoproteinemia
Beta-VLDL
Tangier's disease
Lipoprotein Lipase deficiency
Mild form of LCAT deficieny
Cat eye disease
Fish eye disease
Dog style disease
Scalded scale disease
Other term for Abetalipoprotenemia
Anderson's disease
Tay-sach's disease
Tangier's disease
Bassen-Kornzweig syndrom
Inherited nerurodegenerative disorder of lipid metabolism characterized by deficiency in Hexosaminidase A
Anderson's disease
Tay-sach's disease
Tangier's disease
Bassen-Kornzweig syndrom
These are macromolecules composed of polymers of covalently linked amino acids that are involved in every cellular processes
Lipids
Lipoproteins
Proteins
Cholesterol
Consists of a protein and nonprotein moiety
Simple proteins
Conjugated protein
Amphoteric protein
Primary protein
Chemical messengers that control the actions of specific cells or organs
Hormones
Glands
Steroids
Produced by B-cells that mediates immune response
Hormones
Enzymes
Globulin
Immunoglobulin
Protein present in highest concentration in serum
Pre albumin
Albumin
Globulin
Post albumin
Pre albumin is rich in ___ and contain ____
Tryptophanase and 0.7% carbohydrate
Tryptophan and 0.5% carbohydrate
Tryptophan and 0.8% choleterol
Tryptophanase and 0.5% cholesterol
It is used as landmark to conform that the specimen is really specimen
Pre albumin
Albumin
Post albumin
Globulin
Reference value for fatty acids
150-380 mg/dL
8-12 mg/dL
9-15 mg/dL
Fasting requirement for triglycerides
8-12 hrs
12-14 hrs
24 hrs
48 hrs
Reference value for phospholipids
150-380 mg/dL
8-12 mg/dL
9-15 mg/dL
Desirable Reference value for cholesterol
< 200 mg/dL
200-239 mg/dL
> 240 mg/dL
> 200 mg/dL
Proteins are composed of?
30-40% of cell's dry weight
50-70% of cell's dry weight
10-15% of cell's dry weight
Also known as orosomucoid and the diagnostic pool for neonates with bacterial infection
Alpha 1 - Antichymotrypsin
Alpha 1 - Acid glycoprotein
Alpha 1 - Antitrypsin
Neutralizes trypsin-like enzymes and a major inhibitor of protease activity
Alpha 1 - Antichymotrypsin
Alpha 1 - Acid glycoprotein
Alpha 1 - Antitrypsin
A serine protease with cathepsin G and it binds and inactivates prostate-specific antigen
Alpha 1 - Antichymotrypsin
Alpha 1 - Acid glycoprotein
Alpha 1 - Antitrypsin
Complexes of protein and lipids
Lipoprotein
Beta 2 - Microglobulin
Complement
Participates in the immune reaction and serve as a link to the inflammatory response
Lipoprotein
Beta 2 - Microglobulin
Complement
Binds heme released by degradation of hemoglobin
Fibrinogen
Hemopexin
C-reactive protein
One of the largest proteins in the blood and the most abundant of the coagulation factors
Lipoprotein
Beta 2 - Microglobulin
Complement
Fibrinogen
Light chain component of the Human Leukocyte Antigen (HLA)
Immunoglobulins
Beta 2 - Microglobulin
Lipoprotein
Fibrinogen
Used for the identification of charged particles in an electric field
Electrophoresis
Serum protein electrophoresis
Salt Fractionataion
Albumin
Reagent used for Salt fractionation
Hydrogen peroxide
Sodium Salt
Calcium Salt
NaOH
Principle: Based in the measurement of the nitrogen content of protein
KJELDHAL
REFRACTOMETRY
BIURET
Principle: Cupric ion complex involved in the peptide bond forming a violet-colored chelate
KJELDHAL
REFRACTOMETRY
BIURET
Deposition of copper in skin, brain, and cornea
Anderson's disease
Tangier's disease
Wilson's disease
Malnutrition
Major end product of protein and amino acids catabolism
Ammonia
Creatinine
Blood Uric Acid
Blood Urea Nitrogen
Major product of purine catabolism in the liver
Creatinine
Blood Uric Acid
Blood Urea Nitrogen
Ammonia
Product of muscle metabolism derived from creatinine
Ammonia
Creatinine
Blood Urea Nitrogen
Blood Uric Acid
By product of amino acid determination
Creatinine
Blood Urea Nitrogen
Ammonia
Blood Uric Acid
Reference value of BUN
8-13 mg/dL
2-14 mg/dL
6-20 mg/dL
Fasting sample isrequired for BUN and Creatinine
True
False
Lloyd's reagent
Sodium Aluminum Silicate
Aluminum Mg Silicate
Fueller's Earth Reagent
Sodium Aluminum Silicate
Aluminum Mg Silicate
Deficiency of HGPRT
Lesch-Nyhan syndrome
Chronic renal disease
Gout
Nephrotoxicity
Ammonia is measured with?
Heparinized Red Tube
Heparinized Green Tube
Heparinized EDTA
Elevated levek if nitrogenous substances like urea and creatinine in blood
Urease
Azotemia
Thisemicarbazide
Ferric ions
UREA + DAM --> ???
Yellow diazine derivative
Yellow diamine derivative
Yellow deoxysocholate
Yellow Power Ranger
Chemical method for BUN
Diacetyl Monoxime Method
Isotope Dilution Spectrometry
Hydrolysis of urea by urease
Creatinine + Alkaline Picrate = ?
Alkaline creatinine picrate
Alkalicreatinine
Creatinine Alkaline
Creatinine picrate
Rate of change of absorbance
Jaffe kinetic
Direct Jaffe reaction
Jaffe with absorbent
Largest organ weighing approximately 1.2 - 1.5 kg
Stomach
Liver
Kidney
Heart
Principal pigment of Bile
Bilirubin
Bile acids
Chromagen
Bilirubin
Functional Unit of the liver
Lobules
Bowman's capsule
Hepatocyte
MX3
A chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissues
Cirrhosis
Faciform disease
Hepatocyte
Engulf bacteria, debris, tixins, and other substances following through sinusoids
Hepatocyte
Macrophages
Cholesterol
Formed dues to prolonged elevation of conjugated bilirubin in biliary obstruction
Alpha bilirubin
Beta Bilirubin
Delta Bilirubin
Gamma Bilirubin
Jaundice that is not noticeable in the naked eye
Overt jaundice
Newborn Jaundice
Jaundice
"Bilirubin transport deficit" that is characterized by impaired cellular upatake of bilirubin
Dubin-Johnson Syndrome
Gilbert's disease
Crigler Najjar Syndrome
Rotor Syndrome
Kernicterus
Inherited disorder of bilirubin metabolism resulting from molecular defect within the gene involved with bilirubin conjugation
Dubin-Johnson Syndrome
Gilbert's disease
Crigler Najjar Syndrome
Rotor Syndrome
Kernicterus
Results in cell damage and death
Dubin-Johnson Syndrome
Gilbert's disease
Crigler Najjar Syndrome
Rotor Syndrome
Kernicterus
"Bilirubin excretion deficit" which is obstructive in nature
Dubin-Johnson Syndrome
Gilbert's disease
Crigler Najjar Syndrome
Rotor Syndrome
Kernicterus
"Bilirubin excretion deficit" which its defect causing is not known
Dubin-Johnson Syndrome
Gilbert's disease
Crigler Najjar Syndrome
Rotor Syndrome
Kernicterus
Single collection method of Bromsulfonthalein (BSP) dye excretion test
Rosental White
Mac donald Method
Double collection method of Bromsulfonthalein (BSP) dye excretion test
Rosental White
Mac donald Method
Colorless end product of Bilirubin metabolism that is oxidized by intestinal bacteria to brown pigment
Urobilinogen
Urobilin
Reference value for urine urobilinogen
0.1 - 0.5 Ehrlich units/3 hrs
0.1-1.0 Ehrlich units / 2 hours
0.1-1.0 Ehrlich units / hour
Reference value for urobilinogen (feces)
75-275 units/100 g feces
75-275 units/50 g feces
60-100 units/100 g feces
Is a bitter-tasting, dark green to yellowish brown fluid, produced by the liver
Bile
Bilirubin
Hepatocyte
Bile acids
How many days does the RBC phagocyted?
120 days
126 days
100 days
Popular technique to discreet analyzers
Evelyn and malloy method
Jendrassik and Grof Method
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