Pharmacology Midterm Review
Pharmacology Midterm Review Quiz
Test your knowledge and prepare for your pharmacology midterm with this comprehensive quiz! Designed for students and healthcare professionals alike, this quiz covers essential topics in pharmacology.
- 75 Multiple Choice Questions
- Evaluate Your Understanding
- Enhance Your Learning Experience
Which type of drug name usually begins with a lowercase letter?
Brand name
Code name
Generic name
Trade name
The federal body that determines whether a drug is considered a controlled substance and to which schedule it belongs is the
Food and Drug Administration (FDA).
Federal Trade Commission (FTC).
Drug Enforcement Administration (DEA).
U.S. Pharmacopeia (USP)
Which federal regulatory agency decides which drugs require a prescription and which drugs may be sold over-the-counter (OTC)?
FDA
OSHA
FTC
DEA
The word stat on a prescription means
Before meals.
At bedtime.
Immediately.
Every.
The abbreviation used on prescriptions for four times a day is
Bid
Qid.
Qd.
Ud.
Which of the following statements is true regarding the therapeutic index (TI) of a drug?
A drug with a large TI is more dangerous than a drug with a small TI.
ED is 50% of the effective clinical dose.
TI is the ratio of the median lethal dose to the median effective dose.
None of the above
The distribution of a drug is determined by
Blood flow to the organ
Presence of certain barriers.
Plasma protein–binding capacity
Solubility of the drug.
All of the above
The _____ is the most common site for biotransformation.
Kidney
Blood plasma
Liver
Small intestine
If a drug displays zero-order elimination kinetics
Elimination increases as the dose of the drug is increased.
A constant amount is eliminated per unit time.
The drug is not eliminated and is retained in the body.
The elimination of the drug cannot be predicted mathematically.
An enteral route of administration would be
Intravenous.
Oral.
Sublingual.
Transdermal.
Which organ is involved in the first-pass effect after oral administration of a drug?
Kidney
Lungs
Liver
Spleen
A patient’s perception that a pill without active ingredients is having a pharmacologic effect is termed
Tachyphylaxis.
Hypersensitivity.
Neurosis.
Compliance.
Placebo effect.
A drug effect that is neither predictable nor dose related is called a
Therapeutic effect.
Toxic reaction.
Side effect.
Drug allergy.
The greatest risk to the fetus from exposure to drugs occurs
Just before birth.
During the third trimester
During the second trimester.
Before pregnancy status is known
An acute, life-threatening allergic reaction characterized by hypotension, bronchospasm, laryngeal edema, and cardiac arrhythmias is what type of hypersensitivity?
Type I
Type II
Type III
Type IV
Which is safe to administer to a pregnant patient?
Tetracycline
NSAIDs
Penicillin
Benzodiazepines
The acronym SLUD denotes adverse reactions associated with administration of _____ agents.
Cholinergic
Anticholinergic
Adrenergic
Antiadrenergic
Which drug would be best to treat xerostomia?
Atropine
Propranolol
Pilocarpine
Pseudoephedrine
Stimulation of β2-receptors results in
Vasoconstriction of skin and skeletal muscle.
Increase in heart rate and force of contraction
Smooth-muscle relaxation.
Bronchoconstriction.
Which of the following raises the pain threshold?
Sleep
Sympathy
Analgesics
All of these
The action of nonopioid analgesics is related to their ability to inhibit
The CNS.
Prostaglandin synthesis
Release of epinephrine.
Release of acetylcholine.
Which of the following choices has anti-inflammatory, antipyretic, analgesic, and antiplatelet action?
Acetaminophen
Codeine
Aspirin
Hydrocodone
A drug interaction between aspirin and _____ can result in significant bleeding.
Probenecid
Warfarin
Methotrexate
Sulfonylureas
Which of the following is true concerning NSAIDs?
Many prescribers agree that the NSAIDs are the most useful drug group for the treatment of dental pain.
Unlike aspirin, NSAIDs do not inhibit the enzyme cyclooxygenase (COX).
Most NSAIDs reach a peak blood level in approximately 20 minutes
NSAIDs do not have a significant anti-inflammatory effect.
Which of the following NSAIDs is the drug of choice for treating a nursing woman?
Naproxen
Diflunisal
Ibuprofen
Fenoprofen
Acetaminophen does not possess any of these clinically significant _____ effects: (1) antipyretic, (2) anti-inflammatory, (3) analgesic.
1,2,3
1 and 2
1 and 3
1
2
What do aspirin, acetaminophen, ibuprofen, and codeine have in common?
They are all antiinflammatory.
They are all analgesic.
They all inhibit platelet aggregation.
They are all antipyretic.
___ is usually the cause of death with an overdose of opioid analgesics.
Tachycardia
Respiratory depression
Electrolyte imbalance
Cellular necrosis
Which is an advantage of the nonsteroidal antiinflammatory drugs (NSAIDs) over the opioids for the management of dental pain in an opioid addict?
They are not addictive.
They are antitussive.
They are all useful if the patient is pregnant.
They cause less fluid retention (edema).
Tylenol #3 contains _____ mg of codeine.
7.5
15
30
60
Dental caries is caused by an infection with
Porphyromonas gingivalis
Eikenella corrodens
Streptococcus mutans
Fusobacterium
If an infection is just beginning, the organisms most likely to be present are
Gram-positive cocci.
Gram-negative cocci.
Gram-positive anaerobes.
Gram-negative anaerobes.
Which of the following antibiotics is associated with pseudomembranous colitis?
Penicillin
Erythromycin
Clindamycin
Metronidazole
The disease-producing power of the microorganism is called
Resistance.
Superinfection.
Infection.
Virulence.
Superinfection is more often caused by _____-spectrum antibiotics and increases when taken for a _____ time period.
Narrow; shorter
Narrow; longer
Broad; shorter
Broad; longer
Is the drug of choice for prophylaxis to prevent bacterial endocarditis before a dental procedure
Penicillin G
Penicillin V
Ampicillin
Amoxicillin
A cephalosporin would be most closely related to which of the following agents?
Penicillin VK
Clarithromycin
Ciprofloxacin
Doxycycline
Clindamycin
Tetracyclines should not be used in children younger than _____ years of age.
11
9
12
15
Is associated with a severe drug interaction with alcohol.
Erythromycin
Tetracycline
Metronidazole
Aminoglycosides (e.g., streptomycin)
Nystatin is used for both the treatment and the prevention of _____ in susceptible cases.
Blastomycosis
Histoplasmosis
Oral candidiasis
Tinea
Viruses are difficult to treat because they require cooperation with the host’s cells to replicate
True
False
Topical acyclovir
Will prevent the transmission of herpes labialis
Has been effective in the treatment of herpes labialis infections in nonimmunocompromised patients.
Does not prevent the recurrence of herpes labialis
None of the above
A person with hepatitis _____ is most likely to develop chronic hepatitis.
A
B
C
D
Which of the following local anesthetics is cautioned for use during an inferior alveolar block due to the risk of nerve damage?
4% Septocaine/articaine
2% lidocaine
3% Carbocaine/mepivacaine
0.5% Marcaine/bupivacaine
All can be used without concern for any dental anesthesia.
Addition of vasoconstrictor to local anesthetic (1) reduces blood supply to the area, (2) increases blood supply to the area, (3) limits systemic absorption, (4) increases systemic absorption, (5) reduces systemic toxicity, and (6) increases systemic toxicity. Which of these are correct?
1,3,5
1,4,5
2,3,5
2,3,6
2,4,6
Which of the following local anesthetics is safest to use for dental treatment for a pregnant woman?
Mepivacaine
Lidocaine
Articaine
Bupivacaine
The maximum safe dose of epinephrine for the cardiac patient is _____ mg.
0.02
0.04
0.2
0.4
At the termination of a N2O/O2 sedation procedure, the patient should be placed on 100% oxygen for at least _____ minutes.
2
5
8
11
Nitrous oxide is contraindicated for use in a patient with which of the following conditions?
Diabetes
Emphysema/COPD
Hypertension
Glaucoma
Chronic use of barbiturates can lead to physical and psychologic dependence
False
True
Which of the following is considered to be the strongest centrally acting skeletal muscle relaxant and is used in dentistry for TMD patients?
Ambien
Lunesta
Cyclobenzaprine (Flexeril)
Celebrex
Phase 1 clinical trials involve all of the following except which one?
Safe dose range
Toxic effects of the drug
Metabolism
Effectiveness
On a prescription, the directions to the patient are preceded by
Rx.
Sig.
#.
Disp
In comparing two drugs, the dose-response curve for the drug that is more efficacious would
Be closer to the y-axis.
Be farther from the y-axis.
Have a greater curve height.
Have a higher median effective dose (ED ).
When different drugs compete for the same receptor sites, the drug with the stronger affinity for the receptor will bind to
More receptors than the drug with the weaker affinity.
Fewer receptors than the drug with the weaker affinity.
All of the available receptors
None of the available receptors.
The route of administration of a drug affects
Both the onset and duration of response.
The onset, but not the duration of response.
The duration, but not the onset of response.
Neither the onset nor the duration of response.
Which will block the action of histamine during a medical emergency allergic reaction?
Macrolide
Epinephrine
Anticonvulsants
Benzodiazepines
Which is least likely to be a true allergic reaction?
Urticaria
Rash
Anaphylaxis
Nausea
The autonomic nervous system (ANS) functions as a(n) _____ system for many bodily functions.
Somatic negative feedback
Somatic modulating
Automatic negative feedback
Automatic modulating
The neurotransmitter released from a preganglionic neuron in the sympathetic division of the autonomic nervous system (ANS) is
Epinephrine.
Norepinephrine.
Dopamine.
Acetylcholine.
The S in SLUD stands for
Sympathetic.
Salivation.
Severe.
Secretion.
Agents such as albuterol (Proventil, Ventolin) cause bronchodilation by binding to _____ receptors
Alpha
Nicotinic
Beta1
Beta2
Which of the following is the best to use in pediatric patients for both its analgesic and antipyretic action?
Aspirin
Acetaminophen
Naproxen sodium
Codeine
Which opioid is commonly used as an antitussive?
Propoxyphene
Codeine
Diphenoxylate
Pentazocine
A patient who feels nauseated after taking codeine is allergic to it.
True
False
Which of the following agents is the drug of choice for an early dental infection unless the patient is allergic to it?
Erythromycin
Clindamycin
Penicillin
Metronidazole
The misuse of antibiotics has contributed to antibiotic resistance. The solution to reducing the incidence of antibiotic-resistant bacteria is to write more prescriptions for antibiotics.
Both statements are true.
Both statements are false
The first statement is true, the second is false.
The first statement is false, the second is true.
____ has the highest incidence of gastrointestinal complaints of any of the antibiotics
Penicillin
Erythromycin
Bactrim
Cephalosporin
Which of the following agents is the drug of first choice against infections caused by aerobic microorganisms in penicillin-allergic patients?
Metronidazole
Erythromycin
Doxycycline
Clindamycin
Azithromycin and clarithromycin
Cause lysis of the bacterial cell wall.
Are not effective against anaerobes.
Have a higher incidence of adverse reactions than erythromycin.
May be used as alternative antibiotics for the prophylaxis of endocarditis and prosthetic joint infections.
All of the following are characteristics of the ideal local anesthetic except
Sterilization by autoclave.
Slow onset.
Reversible.
Absence of local reactions.
Patients with uncontrolled high blood pressure, hyperthyroidism, angina pectoris, and cardiac arrhythmias and those who have had a myocardial infarction or cerebrovascular accident in the past _____ should make an appointment for elective dental treatment only after their medical condition is under control
6 weeks
3 months
6 months
12 months
Which of the following agents is the most common topical local anesthetic?
Lidocaine
Benzocaine
Tetracaine
Dyclonine
Which of the following dental specialists is most likely to use general anesthetic drugs in their offices?
Prosthodontist
Endodontist
Oral and maxillofacial surgeon
Orthodontist
Pediatric dentist
Which of the following drugs can be used to treat heroin addiction?
Morphine
Methadone
Naltrexone
Both A and C
Both B and C
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