BioPsych Final sample
Definition: the steps by which drugs are absorbed, distributed, metabolized, and excreted
Black Gangster Disciples, Latin Kings, & M6
Pharmacokinetics
Psychopharmacology
Injection and oral
What is the fastest route to administer drugs?
Inject into abdominal wall
Inject directly into a large muscle
Inject into a vein
Place underneath the tongue
Injection into the space beneath the skin
Intracerebral
Intracerebroventricular
Subcutaneous
Intraperitoneal
4 components (in order) of Pharmacokinetics
Absorption/distribution/metabolism/excretion
Absorption/digestion/metabolism/excretion
Insertion/distribution/indigestion/excretion
Paul, John, George, Ringo
What is a dope-response curve?
The point where drug tolerance increases
Best way to measure effectiveness of drug
Determining point where adverse side effects decrease
Lipid solubility
Term to describe the rate a drug reaches sites of action within the brain
Lipid solubility
Therapeutic index
Metabolism
Dope-response
Therapeutic index
Dose that produces toxic effect in 50% of subjects
Dose that produces desired effect in 50% of subjects
A measure of a drug's margin of safety
Determining point withdrawal symptoms begin
Two reason drugs vary in their effectiveness
Different manufacturers, compound structure
Different sites of action, vary in affinity for binding
Other drug interactions, delayed absorption
Expiration date of drug, improper administration
What prevents the neurotransmitter from activating receptor?
Indirect antagonists
Direct antagonists
Reuptake
Divergents
Binding sites for GABA
Bicuculline, muscimol, diazepam, alprazolam
Bicolax, muscimol, diazepam, anatihistimine
Duramorph, Talwin, diazepam, adzenys
Bicuculline, muscus, desoxyn, alprazolam
Amphetamine and methamphetamine
Receives dopamine and norepinephrine
Releases norepinephrine
Releases dopamine and norepinephrine
Releases dopamine
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