PATHO

What characteristic does Local Immune complex Diseases differ from systemic immune complex disease

There is infiltration of neutrophil causing inflammation

This is accompanied by tissue damage and necrosis

There is an activation of classical complement pathway

Attracted neutrophils and macrophages releases lysosomal enzymes

All of the following are true on Perivascular cuffing EXCEPT

It can be seen in Delayed type hypersensitivity reaction

There is inflitration of mononuclear cells in arteries

Mononuclear cells will become after

None of the above

What is the final result of T cell mediated cytotoxicity

Necrosis

Inflammation

Phagocytosis

Apoptosis

Type of transplant rejection that is involve with activation of C4d classical pathway

Acute Cellular Rejection

Acute Humoral Rejection

Both

Neither

Which of the following related diseases in SLE follow immune complex hypersensitivity reaction

All are TRUE Observed characteristic of Amyloidosis in different lab diagnosis except

In LM it appears as amporphic, basophilic, hyaline

In EM it appears as continous and branching

In X ray crystallograpy and infrared spectroscopy it appears with cross Beta pleated sheet confirmation

None

All of the following are NOT true in the morphology of affected amyloidosis of kidney except:

Grossly it is enlarged, pigmented and waxy

In advanced stage it is shrunken due to deposition of proteins in the venule walls

Microscopically it appears as eosinophilic hyaline intracellular substance

All of the follwing are false

Which of the following is an autosomal recessive condition that is asocciated with excessive production of cytokine IL-1

Hemodialysis-Associated Amyloidosis

Familial Mediterranean Fever

Senise Systemic Amyloidosis

None

What is the correct order of appearance of amyloid in the liver

Space of Disse > Hepatic Parenchymal Cells > SInusoids

Sinusoids > Parenchymal Cells > Space of Disse

Space of Disse >Sinusoids > Parenchymal Cells

Sinusoids > Space of Disse > Parenchymal Cells

There's no amyloidosis occurring in the liver

Which of the following best describes Hemagglutination Inhibition

Positive Result means that there is an Antibody present against Antigen thus there is Agglutination between Ab and Ag coated RBC

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