Immuno exam

Which type of cytokine is secreted by activated Th1?

Receptor TCR on Th cells is able to recognise:

Which type of cells is able to induce cross-priming?

A) macrophages

B) dendritic cells

C) B cells

D) Langerhan's cells

Specific IgM:

A) are secreted by memory cells

B) can cross the placenta

C) in serum usually exist as a monomer

D) are secreted in acute infection during first contact with Ag

How many % of whole lymphocyte pool do constitute lymphocyte Th in whole blood of healthy adult approximately?

Fc fragment of Ig is not responsible to ;

A)ADCC

B) fixation of complement

C) binding to various cell

D) antigen binding

NK cells choose false;

A)represent CD56+CD16+ phenotype

B) their activity is inhibited rather by KIR than KAR receptors recognizing their ligands on target cells

C) are cytotoxic cells taking part in ADCC reaction

d) are an important part of specific antiviral and antineoplasmatic reaction

E) produce perforins and granzymes

Specific phagocytosis is mediated by:

A) Fc receptors on phagocyte

B) PRR receptors

C) Scavenger receptors on the bacterial cell

D.Toll-like receptors on the bacterial cell

E.PAMP receptors on the phagocytes

9. Choose the feature of classic complement pathway:

A) is activated by pathogen opsonized with IgM/IgG

B.is activated by mannose

C.during its’ activation, chemotactic factors C3b, C5b are created

D. factor P deficiency can cause its excessive activation resulting hereditary angioedema

E. The final product of its activation is C3 convertase

10. Choose false about phagocytosis:

A.lymphocytes, neutrophils, eosinophils posses phagocytic activity

B) purulent reaction is the final effect of phagocytosis

C) the professional phagocytic cells are neuropiles and macrophages

D) hydrogen peroxide dismutase participate in oxygen- dependent killing phagocytosis

E) is more effective with opsonines

Which of the following is the earliest cellular component released during primary viral infection?

Which of the following represent the effectory cells during parasitic infections?

A. eosinophils

B) neutrophiles

C) macrophages

D) platelets

3.Which of the following represent bacterial molecules involved in phagocytosis?

4.What is the major effectory mechanism in extracellular bacteria elimination?

5. Choose which of the following describe the IFN α/β mode of action during viral infections.

6. Which of the following belong to the opportunistic infections?

7.Which of the following represent phagocytosis defects?

A) di George syndrome

B) Bruton's syndrome

C) SCID

D) chronic granulomatous disease (CGD)

8. Which of the following represents the most common primary immunodeficiency?

9.Which of the following represent the symptoms of Wiskott- Aldrich syndrome?

10. Choose false about SCID

A) this is an example of benign immunodeficiency

B) all patients represent the same immunophenotype

C) impaired immunoglobulines production is the only manifestation

D) severe opportunitic infections are common in the course of this syndrome

E) this is treated with bone marrow stem cells transplantation

1.Which laboratory findinges can be present in autoimuune diseases

A) high level of suppressor T lymphocytes

B) decrease of immunoglobulin level

C) high level of complement concentration

D) high level of eosinophils

E) presence of immunological complexes in serum

2.Injection of serum containing exogenous protein can result in:

Immuno exam

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