POSAHIT RECAP
Master the Science of Mucormycosis and Posaconazole
Test your knowledge on the antifungal agent posaconazole and its application in treating mucormycosis. This quiz contains 10 thought-provoking questions designed for medical professionals and students alike.
What you can expect:
- Detailed questions about posaconazole's mechanism of action.
- Information on antifungal efficacy against mucorale species.
- Insights into mucormycosis management in COVID-19 patients.
Which one of the following statement is true regarding posaconazole mechanism of action?
It blocks the synthesis of ergosterol
It blocks protein synthesis
It creates artificial pores in fungal cell wall
None of the above
Which one of the following antifungal agents has got no activity against mucorale species?
Isavuconazole
Posaconazole
Liposomal amphothericin B
Voriconazole
Which is the most common and most aggressive form of mucormycosis?
Pulmonary mucormycosis
Gastrointestinal mucormycosis
Rhino-cerebral mucormycosis
Cutaneous mucormycosis
Which one of the following is not an approved Indication of Posaconazole?
Prophylaxis for invasive Aspergillus in high risk patients
Prophylaxis for candida infection in high risk patients
Prophylaxis for zygomycosis
Treatment of oropharyngeal candidiasis
Which one of the POSAHIT formulation is currently not available in India?
Oral suspension 50mg/ml
Gastro resistant tablets 100mg
Injection 300mg/16.7 ml
Oral suspension 40mg/ml
Which one of the following antifungal agent has got highest potency against mucormycosis?
Isavuconazole
Posaconazole
Liposomal amphothericin B
Voriconazole
How much is the loading dose of POSAHIT tablet for prophylaxis of invasive aspergillus and candida infection?
300mg once a day on first day
300mg twice a day on first day
300mg thrice a day on first day
300mg thrice a day on first day
Which of the following is high risk factor or predisposing factor for mucormycosis infection?
Poorly controlled diabetes
High-dose glucocorticoid therapy
Patients with hematological malignancy
All of the above
Which one of the following statement is true regarding POSAHIT?
Injection is indicated for patients 13 years of age and older
Tablets and oral suspension are indicated for paediatric patients 13 years of age and older
Tablets and oral suspension are indicated for patients less than 13 years of age
Injection is indicated for patients less than 13 years of age
As per the ICMR guidelines, which one of the following statement is true for management of Mucormycosis in Covid – 19 patients?
Liposomal Amphotericin B should be used as initial therapy followed by step down approach to oral posaconazole
Posaconazole should be used as initial therapy followed by step down approach to Liposomal Amphotericin B
Isuvaconazole should be used as initial therapy followed by step down approach to Liposomal Amphotericin B
Liposomal Amphotericin B should be used as initial therapy followed by step down approach to oral voriconazole
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