Histology 2D

A detailed and educational infographic illustrating various blood cell types, including erythrocytes, leukocytes, and platelets, with annotations about their fun<wbr>ctions and characteristics in a colorful and engaging style.

Histology 2D Quiz

Test your knowledge of hematopoiesis, blood cells, and bone marrow with our engaging Histology 2D quiz. This quiz is designed to challenge students and enthusiasts alike, providing a comprehensive review of key concepts in hematology.

Features:

Multiple-choice questions covering various aspects of blood cell types
Interactive checkboxes for easy answering
Perfect for students, teachers, and anyone interested in histology

32 Questions8 MinutesCreated by StudyingCells202

Hematopoiesis

Is the process of the blood production

Takes place in the red bone marrow

Involves proliferation and differentiation of cells

All blood cells arise from a single hematopoietic stem cell

During granulopoiesis, specific granules are synthesized in myelocytes

Takes place in the thymus

Erythrocytes:

Cannot leave the blood vessels by diapedesis

Transports oxygen and carbon dioxide

Are anucleated

Lysosomes are present in its cytoplasm

Survives circulation for ≈ 120 days

Decreased number is referred to as anemia

Reticulocytes consitute ≈ 1% of all circulating erythrocytes

Are biconcave in shape

Leukocytes:

Are divided into granulocytes and agranulocytes

Neutrophils are active phagocytes of bacteria

Specific granules of eosinophils contains major basic protein (MCB)

Basophils have receptor for IgE

Neutrophils are less numerous than eosinophils

When activated B lymphocytes proliferate to produce plasma cells

Specific granules are more abundant in neutrophils

Platelets:

Release blood-clotting factors

Are anucleated

Originate from megakaryocytes

Are the predominant cells of the blood

Contains granules, glycogen and mitochondria

Are composed of hyalomere and granulomere

Have granules containing ADP

Platelets originate in the thymus

Neutrophils:

Have a multilobed nuclei

Contains specific granules

Their tertiary granules contains glycoproteins that are dedicated for insertion into the cell membrane

Main function is to phagocytose and destroy bacteria

Erythropoiesis:

Is stimulated by EPO

Pro erythroblast is the precursor for the erythrocyte

Reticulocytes are nucleated

Reticulocytes are filled with hemoglobin

Reticulocytes contain residual ribosomal RNA

What is true regarding stem cells and differentiation?

Differentiation is not the same as proliferation

Differentiation can occur postnatally

Stem cells can not be recognized according to their morphological features

Precursor cells does not leave the bone marrow in normal conditions

The amount of yellow bone marrow decreases with age

Lymphocytes:

Can produce immunoglobulin

Makes up 20-40% of the leukocytes

All lymphocytes originate in the bone marrow

Type B lymphocytes produce antibodies

Their progenitor cells originate in the bone marrow

Their progenitor cells originate in the thymus

Hemopoiesis

All blood cells arise from a single hematopoietic stem cell

Takes place in the yellow bone marrow

Involves only proliferation of cells

During granulopoiesis, specific granules are synthesized in myelocytes

Basophils:

Have a S-shaped bilobulated nuclei

Belongs to the agranulocytes

Contains specific granules

Are the least numerous of white blood cells

Contains heparin and histamine in their granules

Has the IgE receptor on its surface

What is true regarding platelets?

Derive from large polyploidy cells called megakaryocytes

Main function is blood clotting

Are the most abundant in blood

Contains a nuclei

What is true regarding hemopoiesis?

Hemopoiesis depends on a microenvironment with specific endocrine, paracrine and juxtacrine factors

Lymphocytes develop from lymphoid cell

Red blood cells develop from myeloid cell

Hemopoietic growth factors promote cell differentiation and maturation within specific lineages

Granulocytes develop from myeloid cells

During granulopoiesis, specific granules are synthesized in myelocytes

Hematopoietic stem cells:

Are able to response for a growth factor stimulation

All blood cells are derived from one hematopoietic stem cell

Are unable to self-renew

Their morphology is similar to lymphocytes

First stage of nondividing cells during erythropoiesis is:

Proerythroblast

Reticulocyte

CFU-E

Ortochromatophilic erythroblast

Megakaryocytes:

What is true regarding blood?

Red blood cells have a lifespan of ≈ 14 days

Erythrocytes often leave the circulatory system and migrate to tissues

The reticulocytes are not fully mature erythrocytes

Agranulocytes does not have any granules in their cytoplsam

Membrane of normal erythrocytes are highly flexible

Connection: blood cells - feature

Eosinophils - increase in number during parasitic infections

Eosinophils - have an 8-10 lobed nucleus

Lymphocytes B - mature in the thymus

Lymphocytes T - mature in the thymus

Monocytes - secrete antibodies

What is true regarding blood?

Plasma contains fibrinogen

Serum contains fibrinogen

The reticulocytes are not fully mature erythrocytes

Lymphocytes constitute 4-8% of all circulating leukocytes

What is the inductive role of levels of bone morphogenic proteins?

High levels - formation of epidermal ectoderm

Intermediate levels - induction of the neural crest

Low levels - formation of neural tissue

High level - induction of neural crest

Low levels - formation of epidermal ectoderm

What is true regarding the bone marrow?

Great number of adipose cells are present in the yellow bone marrow

Red bone marrow is present in flat bones and vertebrae

Red bone marrow is the place of maturation for T-cells

Red bone marrow is not hematogenous

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Histology 2D

Histology 2D Quiz

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