Chapter 7: Biologic Response to Orthopaedic Implants
Orthopaedic Implant Response Quiz
Test your knowledge on the biologic responses to orthopaedic implants! This quiz covers essential concepts in biological reactions, material properties, and the physiology of implants in orthopaedic settings.
- 11 engaging multiple-choice questions
- Covers key biological and mechanical principles
- Ideal for students, professionals, and enthusiasts in orthopaedics
What biological chemical factors are released after surgical insult? (choose single best answer)
RANKL and RANK
Inflammatory cytokines and chemotatic agents inc. TNF, IL-6, IL-8, NO
Macrophages and leukocytes only
TNF, IL-2, IL-6, IL-8, PDGE
What level of movement around a prosthesis will lead to fibrous tissue formation? (single best answer)
25 um
75um
150um
50um
Any motion not matter how small
250um
What is the optimal pore size to allow ingrowth onto a prosthesis? (singe best answer)
25um
75um
150um
100um
250um
50um
What is osteolysis?
Macrophage response to polyethene particulate 0.1-1.0 microns leading to activation of the OB and OC via the RANK pathway
Particle associated periprosthetic bone loss
Radiographic features associated with bone loss due to wear
All the above
Which of the following is correct?
RANK activates osteoblasts
RANKL activates osteoclasts
RANK is located on osteoclasts
RANKL is located on osteoclasts
RANK is located on osteoblasts
Annealing/Remelting
Remelting melts below the melting point
Annealing removes more free radicles than melting
Annealing melts above the melting point
Annealing improves wear by preserving more of the crystalline structure, has more free radicles than remelting
MoM wear is low because: self-polishes, small radial clearnance, has fluid film lubrication?
True
False
MoM debris is:
Smaller in volume(quantity) and smaller in size than poly
Smaller in volume (quantity)and larger in size than poly
Larger in volume (quantity) and smaller in size
Larger in volume(quantity) and larger in size
MoM reactions cause:
Type 1 hypersenstivity
Type 2 hypersenstivity
Type 3 hypersenstivity
Type 4 hypersenstivity
Type 5 hypersenstivity
Reaming a bone does what to the blood supply?
Nothing
Destroys the periosteal blood
Destroys the endosteal blood supply
Improves endosteal blood supply
Creates a centrifugal blood supply
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