Gout
Mastering Gout: Test Your Knowledge
Welcome to the Gout Quiz! This quiz is designed for anyone looking to deepen their understanding of gout, its treatments, and the medications used in managing this condition.
Test your knowledge with challenging multiple-choice questions that cover:
- The mechanisms of common gout medications
- Natural products used in gout treatment
- Routes of administration for gout therapies
Colchicine is a natural product used to prevent/treat acute attacks of gout, which sentence is not true
Does not affect uric acid serum levels
Retards inflammation from deposition of irate crystals
Reduces anti-inflammatory chemical mediators
Beneficial to combine with Uricosuric agents
Conversion of allopurinol to alloxanthine results in
Lower affinity to XO
Longer half life
Loss of activity
Higher bioavailability
Which drug treats gout through this mechanism
- Xanthine mimic and competitive inhibitor of Xanthine oxidase
- Inhibits synthesis of uric acid --> decrease plasma urate monoanion concentration
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Febuxostat is used for treatment of gout and is preferred over allopurinol in some patients to avoid
Inhibition of xanthine oxidase
Side effects
Short duration
Extensive metabolism
Lesinurad is a treatment for gout which is combined with allopurinol to offer dual mechanism of action, which structure is lesinurab
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The route of administration of pegloticase is
Oral
IM injection
IV injection
Subcutaneous injection
Which is not true regarding pegloticase
Recombinant modified mammalian uricase
Indicated for patients where traditional small molecule therapy has failed
Converts urate into uric acid
Has unique mechanism of action
Which drug has this mechanism of action
- inhibits URAT1
- decreases reabsorption of hate & promotes its excretion
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The following drug acts by decreasing uric acid synthesis
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The following drug doesn’t affect uric acid synthesis
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Other
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