Test Your Knowledge on Primary Immunodeficiency Diseases

An educational illustration showing human immune cells interacting in a healthy body, with highlighted areas indicating primary immunodeficiencies, in a bright and informative style.

Test Your Knowledge on Primary Immunodeficiency Diseases

Welcome to the Primary Immunodeficiency Diseases Quiz! This quiz is designed to test your understanding of various aspects related to primary immune deficiency diseases, their symptoms, diagnosis, and treatment. Whether you're a parent, a student, or just curious about immunology, this quiz will enhance your knowledge and awareness.

Take the quiz to discover:

Key indicators of primary immunodeficiency diseases
Common tests used for diagnosis
Important conditions associated with immunodeficiencies

15 Questions4 MinutesCreated by UnderstandingCell234

Frequent or recurrent types of which of the following infections may strongly indicate the presence of a primary immunodeficiency disease?

Streptococcal pharyngitis

Ear and sinus infections

Urinary tract infections

Viral upper respiratory tract infections

Which of the following would be most worrisome for the presence of a primary immunodeficiency disease consisting of a problem with T lymphocyte function?

Recurrent ear, sinus and lung infections

Recurrent thrush or no thymus on CXR

Recurrent skin abscesses or poor wound healing

Recurrent warts

Which of the following would be most worrisome for the presence of a primary immunodeficiency disease consisting of a problem with neutrophil function?

Recurrent ear, sinus and lung infections

Recurrent thrush or no thymus on CXR

Recurrent skin abscesses or poor wound healing

Recurrent warts

My child has a very high serum IgE level. I should be concerned that he or she may have hyper-IgE syndrome if he or she also has which of the following?

Asthma

Eczema

Skin abscesses

Low platelet count

Which of the following tests might a doctor use to evaluate for defective B lymphocyte function in my child?

Measurement of antibody level in the blood

Oxidative burst assay

Skin testing to Candida or mumps

Newborn screening

Which of the following tests might a doctor use to evaluate for defective T lymphocyte function?

Measurement of chloride levels in sweat

Oxidative burst assay

Skin testing to Candida or mumps

Ciliary biopsy

True or false: All patients with primary immunodeficiency diseases require immunoglobulin replacement therapy to prevent infections.

True

False

The most frequently diagnosed form of specific primary immunodeficiency is:

Data handling for a diagnosis: Given these results from a 4 year-old child, which one PID is most likely?

[Normal range for age is in brackets]

CD3 T cells 2.6 × 109/1 [1.0”7.2 × 109/1]

CD4 T cells 1.8 × 109/1 [0.5”5.2 × 109/1]

CD8 T cells 0.7 × 109/1 [0.4”2.8 × 109/1]

NK cells 0.4 × 109/1 [0.13”0.8 × 109/1]

B cells 0 × 109/1 [0.2”2.7 × 109/1]

Total lymphocytes 3.3 × 109/1 [1.1”5.2 × 109/1]

Which one of the following is most pertinent to healthy individuals with selective IgA deficiency?

All individuals can be considered to be normal without risk of infections.

They are more likely to develop heart disease than those with normal IgA levels.

They have a high risk of a recurrent serious bacterial infection.

They have a higher risk of developing an organ specific autoimmune disease than the general population.

Which one of the following is most pertinent to common variable immune deficiency disorders?

Patients always present before the age of 10 years

Is due to a single gene defect on the X chromosome

Patients are treated by replacement immunoglobulin, intravenously or subcutaneously

Most patients die from complications of malignancy

Which one of the following is most pertinent to transient hypogammaglobulinaemia of infancy:

Occurs at 3 months of age

Is more pronounced in premature babies

Is linked with autoimmune disease later in life

Involves only the IgA class

Which one of the following is the primary defect in chronic granulomatous disease [CGD]?

Neutrophil production in bone marrow

Neutrophil chemotaxis

Neutrophil intracellular killing of organisms

Opsonization

Test Your Knowledge on Primary Immunodeficiency Diseases

Test Your Knowledge on Primary Immunodeficiency Diseases

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