(Beta) Immunology Quiz (PUM)

Which of the following represent the effects of local histamine activity?
None
All
Skin rubour
D. itching
Oedema
Choose correct accroding the vaccination against tuberculosis:
Vaccination contains live attenuated strain of Mycobacterium tuberculosis
Vaccination contains live attenuated strain of Mycobacterium bovis
Vaccination contains inactive microorganisms
Is done in the first day of life
Is done in the 19th year of life
Choose correct according factors leading to self-tolerance defect:
To esogenous factors we include gender and age
To endogenous factors we include genetic factors
HLA-B27 is a clean allel in patients with myasthenia
Anitgen M5 Streptococcus group A can be a cause of rheumatic fever
Exposition to sun light can be related to characteristic skin lesions in lupus
Choose correct according lymphocytes B:
Characteristic receptor is BCR receptor which is coupled with CD3 molecule
IgM and IgG occur on pristine lymphocytes B
Mature in thymus
Show expression of CD80/CD86
Characteristic differntiation marker is CD15
Choose receptors or/and antigens, which are present in trophoblasts
HLAB
CD46
HLAE
CD59
CD23
Choose false:
Protein antigens do not belong the MHC restriction
IFN-y is the main cytokine stimulating formation of IgE
Th2 ist the population of cells regulating acquired humoral response
IL-4 and IL-3 are main cytokines secreted by Th1
Dendritic cells show the expression of MHC I and MHC II
Choose plasma factors responsible for regulation of complement system:
CR1
CD59
Factor I
Vitonectin
DAF
Choose correct
Antigen HLA are included in autoimmunity and are a diagnostic criteria in every autoimmune disease
Autoantibodies are diagnostic criteria in autoagression disease
Hashimoto disease is a systemic disease
Presence of autoantibodies always evidence a autoimmune disease
Skin, kidneys and joints is a common location of changes in systemic disease
Choose correct according cross-match test(CXM):
Done right before a kidney transplant
Aims if the recipient has antibodies against HLA antigenes occuring in our population
Based on the ADCC reaction
Material from recipient are lymphocytes and from donor serum
Helps in prevention of hyperacute rejection
In the course of progressive systemic sclerosis significant antibodies are
ASMA, Ku, Sm, SS-B
ACA, NOR, Scl-70, PM-Scl70
PLAR2, GBM, SS-A
ANCA, ANA, APCA, ACA
AMA, ASMA, LKM, SLA
Choose correct connection: cell – test(picture):
Neutrophil – Wright test
Lymphocyte – blastic transformation test
Neutrophil – Rosette test
Neutrophil – spontaneous NBT test
Lymphocyte – Killing test
Which from the innate immunity diseases is counted to deficiencies of antibody deficiency
Isolated IgA deficiency
CVID
Bruton’s Agammaglobulinemia
SCID
WAS
Which of the following represent effectory cells of type IV hypersensitivity?
Activated macrophages
All
Neutrophiles
Mast cells
Eosinophils
Which type of cytokine is secreted by activated Th1?
Il-2
Il-10
Il-4
TGF-beta
Perforins and granzymes
Which Ig does activate the classical complement path?
SIgA
IgE
IgG4
IgG3
IgD
Which type of cells is able to induce cross-priming?
Macrophages
Dendritic cells
B cells
Langerhans cells
How many % of the whole lymphocyte pool do constitute lymphocyte Th in the whole blood of a healthy adult approximately?
10-20%
80%
60-70%
50-55%
5-10%
Fc fragment of Ig is not responsible (responsive) to:
ADCC
Fixation of complement
Binding to various cell
Antigen binding
Cycle of Hängerness
NK cells choose false:
Represent CD56+CD16+ phenotype
Their activity is inhibited rather by KIR than KAR receptors recognizing heir ligands on target cells
Are cytotoxic cells taking part in ADCC reaction
Are an important part of specific antiviral and anti neoplastic cell reaction
Produce perforins and granzymes
Make Richi drink a Wodka Redbull 80/20 mix
The presence of hemolysis in the final stage of complement fixation test shows:
Absence of wanted antigen
Presence of wanted antigen
Absence of wanted antibodies
Presence of wanted antibodies
Absence of wanted antigenes and antibodies
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