Check for Understanding (Paroxetine)
Check Your Understanding of Paroxetine
Test your knowledge on Paroxetine, a commonly prescribed SSRI, with this comprehensive quiz. Whether you are a healthcare professional, a student, or simply interested in learning more about this medication, this quiz will help reinforce your understanding.
- 21 thought-provoking questions
- Multiple choice format for ease of answering
- Track your progress and improve your knowledge about Paroxetine
Paroxetine is a SSRI that acts on what neurotransmitter
Norepinephrine
Glutamate
Dopamine
Serotonin
Paroxetine has a broad indication in addition to depression and anxiety that includes
OCD
PTSD
Panic disorders
All of the above
It is the mechanism of action of Paroxetine
Paroxetine blocks the release of serotonin in the presynaptic vesicles
Paroxetine blocks the binding of serotonin to its receptors
Paroxetine blocks the serotonin gate to regulate serotonin reuptake
Paroxetine blocks the presynaptic neuron from producing serotonin
Bioavailability of Paroxetine is low due to
Extensive first-pass metabolism
Easy metabolism in the liver
Fast disintegration upon intake
Drug to drug interactions
Peak plasma concentration of Paroxetine is achieved in
3 hours
5.2 hours
4 hours
30 minutes
Metabolism of Paroxetine is in the
Presynaptic neurons
Kidneys
Liver
Small Intestines
Excretion of Paroxetine is both in the urine and feces
~20% urine and ~80% feces
~64% urine and ~36% feces
~90% urine and ~5% feces
25% urine and 75% feces
Recommended starting dose of Paroxetine
20 mg
5 mg
60 mg
60 mg
Maximum daily dose of Paroxetine
80 mg
50 mg or 60 mg
70 mg
40 mg
Discontinuation of Paroxetine is possible
It can be abrupt like other medications
It should be tapered down by a daily dose of 10 mg
It can be discontinued after 1 week
It is based on patient's preference
Paroxetine is indicated to the following patients
Children
Adolescents
Pregnant patients
Adults
Paroxetine can be prescribed in patients with mania
It should be given to adult manic patients
It should not be given at all
It should be used with caution
None of the above
Paroxetine in pregnancy may increase this risk in newborn
Persistent Pulmonary hypertension in newborn
Autism and ADHD in children
Congenital Heart Disease
Juvenile diabetes
Most common side effects of Paroxetine
Sea sickness-like condition
Nausea
Pulmonary conditions
Vertigo
This society recommends SSRIs as first line therapy for GAD, OCD, panic disorder, social anxiety disorder and for pharmacotherapy of core symptoms of PTSD
American Psychiatric Association
NICE, UK
Anxiety Disorders Association of Canada
Philippine Academy of Family Physicians
The dose range of Paroxetine
10 mg - 60 mg
20 mg - 60 mg
10 mg - 40 mg
5 mg - 60 mg
The half life of Paroxetine
20 hours
26 hours
24 hours
18 hours
The only drug of its class indicated for all five anxiety disorders in addition to major depressive disorder, for OCD, panic disorder, social anxiety disorder, GAD and PTSD
Escitalopram
Sertraline
Paroxetine
Duloxetine
Precautions of Paroxetine
Suicidal thoughts
Akathisia
Serotonin syndrome
All of the Above
Paroxetine cannot be co-administered with
MAO-I
Thioridazine
Pimozide
All of the above
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