Round#1
Antibiotics Knowledge Quiz
Test your understanding of antibiotics and their role in treating infections! This quiz covers essential knowledge that is vital for anyone interested in medicine and healthcare.
Challenge yourself with questions on:
- Mechanisms of action
- Side effects and resistance
- Historical developments
1- Antibiotics treat infections from
A) Viruses
B- Bacteria
C) Fungi
D) All Microbes
2- You always need antibiotics for:
A) Strep throat
B- Ear infections
C) Sinus infections
3- What prompted the World Health Organization to change treatment guidelines for chlamydia, gonorrhea, and syphilis?
A) The same antibiotics work well for all three
B- Scientists have created new antibiotics just to treat these conditions
C- Antibiotics may not work against them anymore
4- Which germ worries health officials the most?
A) Clostridium difficile (C. diff)
B- MRSA (methicillin-resistant Staphylococcus aureus )
C- Drug-resistant tuberculosis
5- I can help tackle antibiotic resistance if I:
A) Share my antibiotics with my family when they are sick
B- Get antibiotics as soon as I feel sick - either directly from the pharmacy or a friend
C) Keep my vaccinations up to date
6- What can happen if I get an antibiotic-resistant infection?
A) I may be sick for longer
B- I may have to visit my doctor more or be treated in hospital
C- I may need more expensive medicine that may cause side effects
D- All of the above
7- Sulfonamides were discovered by
A) Alexander Fleming
B- Elizabeth bugie
C- Albert schatz
D- Gerald domgk
8- Mechanism of sulfonamides’ antibacterial effect is:
A) Inhibition of cell wall synthesis
B- Inhibition of folic acid synthesis.
C- Inhibition of cyclooxygenase.
D) Activation of DNA gyrase.
9- Cephalosporines are drugs of choice for treatment of:
A) Gram-positive microorganism infections
B- Gram-negative microorganism infections
C- Gram-negative and gram-positive microorganism infections, if penicillin’s have no effect
D- Only bactericide infections
10- The most frequent side effect of oral ampicillin is
A) Nausea and vomiting
B- Loose motions
C- Constipation
D- Urticaria
11- The penicillin G preparation with the longest duration of action is
A- Benzathine penicillin
B- Sodium penicillin
C- Potassium penicillin
D- Procaine penicillin
12- The mechanism of fluoroquinolones’ action is:
A- Inhibition of phospholipase C
B- Inhibition of DNA gyrase
C- Inhibition of bacterial cell synthesis
D) Alteration of cell membrane permeability
1st antibiotic was discovered in the year
A) 1935
B- 1928
C) 1981
D) 1948
14- Tetracyclins have following unwanted effects
A) Irritation of gastrointestinal mucosa, phototoxicity
B- Hepatotoxicity, anti-anabolic effect
C) Dental hypoplasia, bone deformities
D- All of the above
15- A single oral dose of the following drug can cure most cases of uncomplicated gonorrhoea:
A- Ciprofloxacin
B- Cotrimoxazole
C) Spectinomycin
D- Doxycycline
16- Penicillin was first used clinically for systemic infections in the year
A) 1926
B- 1935
C) 1941
D) 1957
17- Carbapenems are effective against:
A) Gram-positive microorganisms
B- Gram-negative microorganisms
C) Only bacteroide infections
D) Broad-spectrum
18- Which of the following adverse drug reactions precludes a patient from being rechallenged with that drug in future
A- Itching/rash from penicillin.
B- Stevens Johnson syndrome from sulfamethoxazole-trimethoprim
C- GI upset from Clarithromycin
D- Clostridium difficile superinfection from moxifloxacin.
BOOST QUESTION >>>>>>> 1- This drug has activity against many strains of Pseudomonas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in penicillin allergic patients. Its activity against gram-negative rods is enhanced if it is given in combination with tazobactam
A- Amoxicillin
B- Aztreonam
C- Imipenem
D- Piperacillin
E- Vancomycin
19- Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations:
A- Erythromycin
B- Tetracycline
C- Chloramphenicol
D) Ampicillin
20- Quinolones were discovered as a byproduct of research on the ---------- drug
A- Antimalarial drug
B- Anti TB drug
C- Anti cancer drug
D- Anti fungal drug
21- . Antibiotics inhibiting the bacterial cell wall synthesis are:
A) Beta-lactam antibiotics
B- Tetracyclines
C) Aminoglycosides
D- Macrolides
22- Which of the following cephalosporins has activity against gram negative anaerobic pathogens.
A- Cefoxitin
B- Cefepime
C- Ceftriaxone
D- Cefazoline
23- Which of the following adverse effect is associated with daptomycin.
A- Ototoxicity
B- Red man syndrome
C- QTC prolongation
D- Rhabdomyolysis
24- Select the antibiotic that has a high therapeutic index:
A) Streptomycin
B- Doxycycline
C) Cephalexin
D- Vancomycin
25- The first macrolide to be discovered was
A- Erythromycin
B- Clarithromycin
C- Azithromycin
D- Roxithromycin
26- Antibiotics altering permeability of cell membranes are:
A- Glycopeptides
B- Polymyxins
C- Tetracyclines
D- Cephalosporins
27- Select the sulfonamide drug which is active against Pseudomonas and is used by topical application for prophylaxis of infection in burn cases:
A- Sulfadiazine
B- Silver sulfadiazine
C- Sulfadoxine
D- Sulfamethoxazole
28- Vancomicin has the following unwanted effect
A) Pseudomembranous colitis
B- Hepatotoxicity
C) “Red neck” syndrome, phlebitis
D- A,B,and C all are correct.
29- Antibacterials regarded as generally safe to prescribe in pregnancy.
A- erythromycin
B- cephalosporins
C- tetracyclines
D- A & B
30- Ciprofloxacin was discovered by
A- GSK
B- BAYER
C- Pfizer
D- Nova nordisk
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