Erdolytic product knowledge

name

all is true about erdolytic except

has masked thiol group

converted to METI in liver

After first pass metabolism it becomes active

during metabolism thiolactone ring opens

non of the above

in viscosity graph erdolytic effect was more than double the placebo effect

true

false

all is true about smoking except

A.increase MDA

B.decrease ROS

C.Decrease 8-isoprostanes

D.decrease AAT

A&B

B&C

We can't measure ROS but we can measure ...which is a marker of ROS

Free radicals are related to both oxidative stress and inflammation in COPD patients

True

false

all is true except

oxidants activates proteases

erdolytic activates proteases

oxidants inactivates AAT

erdolytic increase elastin indirectly

8-isoprostanes are elevated in stool of smokers

true

false

Main reason of advantages of Erdolytic over NAC (in molecule) is…………..

8-isoprostanes in NAC only decreased in day.....while erdolytic effect mantained till day .........(نكتب الحاجتين حنب بعض)

erdolytic activates catalase enzyme

true

false

erdolytic decrease IL-6&8 & increases CRP

true

false

B-lactam antibiotics and Erdolytic combination benefits patient in.........

daily dose in erdolytic is 600mg/day = 2 hard gelatin capsule/day

true

false

Bacterial anti-adhesion property in erdolytic inhibits which step in vicious circle hypothesis

number of patients..........objective was to assess both.......&........... .(نكتب الحاجتين حنب بعض)

NAC and erdolytic can decrease the duration of AECOPD While only NAC can decrease risk of hospitalization

true

false

number of patients..............

erdolytic is contraindicated in all of the following except

hypersensitivity

pregnancy

breast feeding

mild liver function

erdolytic high safety and tolerability (give reason) 2 short answers

erdolytic is eliminated in urine

true

false

0

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