Pharmacology colloquium 5

A visually engaging image depicting various pharmacological agents, including pill bottles, a human silhouette with highlighted organs, and symbols of the respiratory system amidst a laboratory background.

Pharmacology Mastery Quiz

Test your knowledge and understanding of pharmacological agents with this comprehensive quiz designed for students, healthcare professionals, and anyone interested in pharmacology. Delve into various classes of drugs, their mechanisms, and applications.

Key Features:

Multiple-choice format with checkboxes
Covers diverse topics including COX inhibitors, glucocorticoids, and respiratory agents
Suitable for self-assessment and learning

92 Questions23 MinutesCreated by StudyingScience57

Steroidal anti-inflammatory drug with the most glucocorticoid activity is

Dexamethasone

Fludrocortisone

Hydrocortisone

Prednisolone

Selective, reversible xanthine oxidase inhibitor of non-purine origin is

Febuxostat

Cyclosporine

Fludrocortisone

Allopurinol

Select TRUE statements about acetylsalicylic acid toxicology:

Acute intoxication signs: vomiting, tachypnea, tinnitus, sweating.

Metabolic acidosis should be treated with sodium bicarbonate I/V

Children may develop Reiter's syndrome

Acute and chronic intoxication is possible

Metabolic alkalosis is detected in the laboratory

Select TRUE statements about side effects associated with NSAID use:

COX-2 inhibition is associated with gastrointestinal toxicity

Medications that selectively inhibit COX-1 have a higher incidence of CV toxicity

Medications that selectively inhibit COX-2 have a higher incidence of CV toxicity

COX-1 inhibition is associated with gastrointestinal toxicity

Select TRUE statements about steroidal anti-inflammatory drugs:

Hydrocortisone replacement therapy is used in case of secondary adrenal insufficiency

Used for autoimmune diseases treatment

Mechanism of action: non-selective COX1 / COX2 inhibition

Can cause iatrogenic Cushing's Syndrome

Methylprednisolone has anti-allergic, immunosuppressive effect

Select clinical effects of glucocorticoids:

Enhance bone resorption

Increase T-ly activation and proliferation

Increase blood glucose

Increase water and Na+ reabsorbtion

Increase protein synthesis in muscle

Select possible symptoms and laboratory changes in case of Methotrexate overdose:

Select TRUE statements about Calcineurin inhibitors:

Inhibit T and B lymphocyte proliferation

Activation of IL-2 secretion

Can be used topically

Indication: Relapsing remitting multiple sclerosis

Side effect: nephrotoxicity

Select indications for the use of Immunomodulatory drugs:

Select therapy options in case of Methotrexate overdose:

Fluid deficit correction with crystalloid solutions IV

No antidote for Methotrexate

Calcium folinate I/V

Antidote: Glucarpidase

Nausea can be prevented with anti-emetics

Possible side effects of prolonged use of laxative agents

Correct statement(s) about Loperamide

most common side effect -constipation

Stimulate peripheral opioid receptors

Reduce fluid loss

most common side effect-diarrhea

indicated for viral or bacteria-induced diarrhea

Correct statement(s) about Metoclopramide

Has prokinetic action

useful as a laxative agent

Inhibits the production of stomach acid

has antiparkinson action

Possible risk of extrapyramidal disorders

Correct statements about proton pump inhibitors

can improve the absorption of calcium and magnesium in the gastrointestinal system

Stable antisecretory effects are achieved after 3-4 days of treatment.

Can cause rebound hypergastrinemia(after long term usage)

Can administrate with antacids

medications must be taken before breakfast

Possible pharmacological groups with anti-emetic action

Possible indications of proton pump inhibitors

Correct statement(s) about antacids

a long duration of action

Affect absorption of other drugs

effective against H.Pylori infection

Stimulate the mucosa healing process in the gastrointestinal system

Neutralizes already secreted HCl

Anti-emetic preparations useful for the control of chemotherapy-induced nausea and vomiting

Select TRUE statements about Metoclopramide:

Peripheral mu opioid receptor agonist in the plexus mysentericus which inhibits intestinal peristalsis is

Select pharmacological group(s) with anti-emetic action:

Select TRUE statements about proton pump inhibitors:

Used in treatment of reflux esophagitis

Delay basal, nocturnal and dietary stimulation of gastric acid secretion

Antisecretory effect

Neutralize already secreted hydrochloric acid

Block H2 histamine receptors

Select indications for Ursodeoxycholic acid:

Select TRUE statements about pilocarpine:

Causes IOF production reduction

Reduces intraocular pressure

� Intraocular flow of fluid through the Schlemm canal

Pharmacological group: M cholinoblocker

Causes miotic effects

Select TRUE statements about topical glucocorticosteroids:

Hydrocortisone is mostly used in case of mild atopic dermatitis

First-choice treatment in case of acne vulgaris

Normalize the differentiation of keratinocytes

Side effect: skin atrophy

Select groups of medications to treat acne vulgaris:

What is TRUE about Isotretinoin mechanism of action and clinical effects?

Comedolytic effect

Intracellular retinoic acid receptor agonism

Antiandrogenic effects

Act on cell differentiation and proliferation, induce cell apoptosis

Anti-inflammatory effect

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Pharmacology colloquium 5

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