Test your knowledge on measurable residual disease with time-limited Venetoclax-based regimens

Which of the following is currently the standard threshold for MRD detection for the majority of clinical trials in CLL? 
10-4 
10-5 
10-6 
10-8 
Discordance between uMRD as detected by PB vs. BM could be due to location of the BM aspirate sample, timing of the BM aspirate, the patient’s treatment status, and/or the compartmentalized nature of CLL. 
True
False
Testing MRD at the level of 10-4 assesses for presence of CLL cells at which of the following thresholds: 
1 in 100 
1 in 1,000 
1 in 10,000 
1 in 100,000 
The estimated 5 year PFS for patients with CLL treated with venetoclax in the frontline setting regardless of EOT MRD status is approximately:  
50% 
60% 
70% 
80% 
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