Histology 2G

A detailed diagram of human skin layers highlighting the epidermis, dermis, and associated structures with labeled cells such as melanocytes, keratinocytes, and Langerhans cells.

Skin Histology Quiz

Test your knowledge on the complexities of skin histology with our interactive quiz! This quiz covers various aspects of skin structure, functions, and derivatives, providing a comprehensive overview of this essential topic.

Explore dermal structures and their origins
Identify skin cell types and their roles
Understand skin derivatives and their significance

38 Questions10 MinutesCreated by StudyingSkin101

What is true regarding the dermis?

It is divided into a papillary and reticular layer

Dermis is poor in blood vessels

Both layers contains collagen and elastic fibers

Its thickness is the same in each region of the body

What is true regarding skin derivatives?

Apocrine sweat glands are limited to the axilla, areola and nipple, around the anus and external genitalia

Sweat glands are ectodermal in origin

Each hair is composed of a shaft of cornified cells and root

The hair follicle is responsible for the production and growth of hair

Hairs are elongated keratinized structures derived from invaginations of the epidermal epithelium

Hairs are mainly found on the palms and soles

What is true regarding the langerhans cells of the skin?

Are derived from the bone marrow

Does not contain a nucleus

Are absent in the stratum spinosum

Are bipolar neurons

Are present mainly in the stratum spinosum

Are located in the stratum lucidum of thick skin

In which layer of the epidermis are desmosomes present in the highest number?

What is true regarding the skin?

Skin contains the SALT system

Keratinocytes of malpighian layer is responsible for the renewal of the epidermis

The arrector pili muscle is formed by smooth muscle cells

Sebaceous glands secrete sebum in the holocrine process

The cells of the stratum basale have low mitotic activity

Dermal reticular layer is composed of irregular dense connective tissue

What is true regarding the epidermis?

There is no stratum lucidum in the thin skin

The stratum basale is also called the stratum germinativum

Stratum lucidum is rich in discontinuous capillaries

Melanocytes are present only in thin skin

Which statements are true regarding skin?

SALT system includes keratinocytes, T-lymphocytes and Langerhans cells

Mammary glands are modified sebaceous glands

Statum basale is also called stratum germinativum

Reticular layer of dermis is composed of dense irregular connective tissue

What is true regarding the skin?

SALT system includes: keratinocytes, T-lymphocytes and Langerhans cells

Reticular layer of dermis is composed of loose CT

Thickness of the dermis varies depening on the region of the body

Bulb region of the hair contains stem cells

Arrector pili muscles are composed of smooth muscle cells

Cells of stratum basale have high mitotic activity

Sebaceous glands are branched multicellular saccular glands

Dermis supports the epidermis and binds it to the hypodermis

In which layer of the epidermis are desmosomes present in the highest number?

Stratum spinosum

Stratum basale

The dermis:

Both layers contains collagen and elastic fibers

Secretory parts of eccrine sweat glands are located in the deeper dermis

Reticular layer is composed of dense irregular connective tissue

A basal lamina is found between the stratum germinativum and papillary layer of dermis

Skin derivatives:

Hair are elongated, keratinized structures derived from invaginations of the epidermal epithelium

The hair follicle is responsible for production and growth of hair

Sebaceous glands secrete sebum that coats hair and skin surfaces

Eccrine sweat glands are distributed over the entire body surface

Each hair is composed of a shaft of cornified cells and a root

Sweat glands are ectodermal in origin

Langerhans cells of the epidermis:

Epidermis:

Is composed of keratinized stratified squamous epithelium

Keratinocytes produce keratins

Keratinocytes are the main population of epidermis

Stratum granulosum contains keratohyalin granules

Stratum basale are mitotically inactive

Epidermis:

It is stratified squamous keratinized epithelium

Does not contain blood vessels

Is derived from the ectoderm

Melanocytes are antigen-presenting cells

Cells in the stratum basale are the most differentiated

What is true concerning the skin?

No bodies of the melanocytes are present in the hypodermis

There are zona occludens between the stratum basale cells and basal lamina

Thick skin covers the palms and soles

Langerhans cells can bind, process and present antigens to T-lymphocytes

In the skin of the external auditory meatus there are only apocrine sweat glands

Melanin is synthesized in melanocytes

No bodies of melanocytes are present in the stratum corneum

No basal lamina is present in the epidermis

Epidermis:

The keratinocytes of the stratum lucidum can proliferate

Is composed of non-keratinizing stratified squamous epithelium

Is derived from the mesoderm

Keratinocytes are the main population of cells

Thick skin:

Contains sweat glands

Contains sebaceous glands

Contains hair follicles

Its stratum lucidum is more apparent than in thin skin

Its typically found on palms and soles

Five layers of epidermis

Thin skin:

Four layers of epidermis

Stratum basale, stratum spinosum, stratum lucidum and stratum corneum

Are found everywhere except palms and soles

Contain hair

Stratum spinosum is the thickest layer

Sweat glands:

Not present in thick skin

Tubular glands

Merocrine secretion

Can be unicellular or multicellular

Sebaceous glands:

Holocrine multicellular saccular glands

Present in thick skin

Secretory portion in dermis

Excretory duct found on surface of skin

Excretory duct opens into hair follicles

Excretory duct is lined with stratified squamous epithelium

Stratum granulosum:

Consists of 3-5 layers of flattened polygonal cells filled with basophilic granules

The granules contain: profilaggrin, involucrin, small proline rich proteins and loricrin

What is true regarding skin?

Sweat glands play a role in regulation of body temperature

Sweat glands are not associated with hair follicles

Melanin is synthesized in melanocytes with tyrosinase

Consists of a malpighian layer

Melanocytes:

Are derived from the neural crest

Are rounded cells with long irregular extensions which branch into the epidermis running between the stratum basale and spinosum

Contains mitochondria, golgi apparatus, cisternae of RER and intermediate filaments

Have poorly developed organelles

Are bound to the basal lamina by hemidesmosomes

Are not attached to adjacent keratinocytes by desmosomes

There are no bodies of melanocytes present in the stratum corneum or hypodermis

Eccrine sweat glands:

Are present everywhere and are always functional

Plays a role in thermoregulation

Secretory portion is convoluted tube composed of three cell types: clear, dark and myoepithelial cells

The fluid secreted is viscous and contains many proteins

The main component is water, sodium chloride, urea, ammonia and uric acid

Mucoid cells are pyramidal and lines most of the luminal surface

Clear cells are devoid of secretory granules

Match layers of epidermis to description:

Stratum spinosum - thickest layer

Stratum basale - deepest layer

Mammary glands:

Consists of 15-20 lobes of compound tubuloalveolar

Lobes are separated by dense CT and adipose tissue and are embedded in intralobular loose CT

Each lobe has a lactiferous duct opening into the nipple that dialate to form lactiferous sinuses lined with stratum sinuses

Lymphocytes in the surrounding CT is responsible for secretion of IgA for the newborn

SALT system:

Sweat-associated lymphoid tissue

Contains keratinocytes which produce thymopoietin

Keratinocytes promotes T-cell maturation

Contains T-lymphocytes and langerhans cells

Skin-associated lymphoid tissue

Appocrine sweat glands:

Are functional after puberty

Secretory portion lies only in the dermis

The excretory duct produces odorless viscous secretion

Secretory portion in the dermis and hypodermis

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