HISTO LEC M1

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Understanding Pathology: Test Your Knowledge

Welcome to the HISTO LEC M1 quiz! This assessment is designed to gauge your understanding of pathology, covering essential concepts such as cell injury, disease mechanisms, and various branches of pathology.

Test your skills and knowledge through a range of questions including:

Multiple Choice Questions
True or False Statements
Identifying Causes of Cell Injury

50 Questions12 MinutesCreated by AnalyzingCell34

Branch of pathology concerned with the common reactions of cells and tissues to injurious/infectious stimuli

GENERAL PATHOLOGY

SYSTEMIC PATHOLOGY

Branch of pathology that examines alterations and underlying mechanisms in disease of particular organ systems

GENERAL PATHOLOGY

SYSTEMIC PATHOLOGY

Branch of pathology with a primary focus on examining tissues with the naked eye or under microscope; most significant and time consuming

Branch of pathology that is highly specialized surgical procedure that is performed by a pathologist and consists of a thorough examination of a corpse to determine the cause and manner of death and to evaluate any disease or injury that may be present

A branch of pathology that studies and diagnoses diseases on the cellular level

A branch of pathology that emphasizes the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids

A medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids

Pathogenesis is the initiating cause of disease

True

False

Etiology is the sequence of molecular, biochemical, and cellular events that lead to the development of disease

True

False

Explains how the underlying etiology produces the morphologic and clinical manifestations of the disease

Etiology

Pathogenesis

Morphological Changes

Clinical Manifestations

The end result of genetic, biochemical, and structural changes in cells and tissues abnormality

Etiology

Pathogenesis

Morphological Changes

Clinical Manifestations

Structural alterations in cells or tissues that are characteristic of a disease and hence diagnostic of an etiologic process

Etiology

Pathogenesis

Morphological Changes

Clinical Manifestations

Signs are clinical manifestations of a disease that a patient may experience

True

False

Symptoms are observable characteristics identified by physician

True

False

Examples of symptoms are headache, pain, body temperature, and weight

True

False

Normal cells should be able to handle physiologic demands, maintaining healthy steady state called

Increase in cell number

Change in phenotype of cells

Increase in size and functional activity of cells

Decrease in size and metabolic activity of cells

Two features of reversible reversible cell injury

Stress to cells

Generalized swelling of the cell

Severe, progressive injury

Fatty Change in organs involved in lipid metabolism

Irreversible cell injury are characterized by functional and structural alterations in early stages or mild forms of injury

True

False

Irreversible cell injury happens if the cell is constantly or repeatedly exposed with injury substances

True

False

Reversible cell injury are correctable if the damaging stimulus is not removed

True

False

Removal of damaged, unneeded, and aged cells

A sequence of events that follows if the limits of adaptive responses are exceeded or cells are exposed to damaging stimuli

Undergone by cells that suffers irreversible injury

In reversible cell injury, cells and organelles usually swell up due to K moving into the cell.

True

False

Blebbing of the plasma membrane and clumping of chromatin happens in irreversible cell injury.

True

False

Irreversible cell injury results to decrease in cell functioning

True

False

Irreversible cell injury leads to series of events that may be seen by lab tests or microscopic infection. Which of the following are true?

If early, ultra-structural changes are seen

If long, enough, lab test documentation

If months or years, changes are seen through light microscope

If years or further, changes can be seen microscopically.

What is the earliest manifestations of cell injury?

Cellular Swelling

Apoptosis

Hemolysis

Fatty Changes

Cell death has two principal types which differ in their mechanisms, morphology, and roles in physiology and disease.

True

False

Characteristics of necrosis

Denaturation of cellular proteins

Denaturation of nucleic acids

Exposure to toxins

Leakage of cellular contents through damaged membranes

Local inflammation

Systemic inflammation

Enzymatic digestion of lethally injured cells

Occurs in many commonly encountered injuries, such as exposure to toxins and various infections.

Necrosis

Apoptosis

A regulated mechanism of cell death that serves to eliminate unwanted and irreparably damaged cells, with the least possible host reactions.

Necrosis

Apoptosis

Which are true in the causes of apoptosis?

Physiologic (mostly)

Physiologic (in some cases)

Pathologic (mostly)

Pathologic (in some cases)

Focal areas of fat destruction, typically due to release of activated pancreatic lipases

Not a specific pattern of cell death; actually a coagulative necrosis usually applied to a limb that has lost its blood supply and undergone necrosis

A special form of vascular damage usually seen in immune reactions involving blood vessels

Chromatin condensation is the most characteristic feature of apoptosis.

True

False

What enzyme activates apoptosis?

Caspases

Lipases

Amylases

Less inflammatory or no inflammatory reaction in the nearby cell death

Necrosis

Apoptosis

Pathologic states of apoptosis: DNA damage and accumulation of misfolded proteins

True

False

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HISTO LEC M1

Understanding Pathology: Test Your Knowledge

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