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Stomach Cancer Quiz: Test Your Knowledge of Symptoms and Care

Quick, free stomach cancer knowledge test. Instant feedback.

Editorial: Review CompletedCreated By: Anthony BurtonUpdated Aug 27, 2025
Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art depicting a quiz on stomach cancer knowledge

This stomach cancer quiz helps you check what you know about symptoms, risk factors, and care in 15 quick questions with instant feedback. If you want to explore related issues, try our stomach pain quiz, learn more with an esophageal cancer quiz, or review signs with a gastroparesis symptoms quiz.

Which symptom is most commonly associated with early stomach cancer?
Persistent epigastric discomfort
Sudden unilateral vision loss
New onset joint swelling
Intermittent itchy rash on elbows
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Which bacterium is a well-established risk factor for gastric adenocarcinoma?
Bacteroides fragilis
Staphylococcus aureus
Clostridioides difficile
Helicobacter pylori
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Which diagnostic test is considered the gold standard for confirming stomach cancer?
Stool guaiac test
Upper endoscopy with biopsy
Barium swallow only
Abdominal ultrasound
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Which symptom suggests advanced gastric cancer rather than early disease?
Intermittent hiccups after soda
Brief nausea after a long trip
Persistent weight loss and early satiety
Occasional heartburn after spicy food
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Which imaging modality is commonly used for staging to detect distant metastases in gastric cancer?
Noncontrast knee MRI
Plain abdominal radiograph only
Transvaginal ultrasound only
Contrast-enhanced CT of chest, abdomen, and pelvis
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Gastric cancer incidence increases with age.
False
True
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Which dietary pattern is most strongly linked to increased gastric cancer risk?
Vegetarian diet rich in legumes
Mediterranean diet
High fresh fruit consumption
High intake of smoked and salted foods
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Which lymph node finding is classically associated with metastatic gastric cancer?
Epitrochlear node
Left supraclavicular (Virchow) node
Preauricular node
Right axillary node
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Which staging tool best assesses the depth of tumor invasion (T stage) in gastric cancer?
Chest X-ray
Colonoscopy
DEXA scan
Endoscopic ultrasound (EUS)
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Which targeted therapy is added for HER2-positive metastatic gastric or gastroesophageal junction adenocarcinoma?
Rituximab
Bevacizumab
Trastuzumab
Erlotinib
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Which laboratory finding supports iron deficiency due to chronic gastric bleeding?
Normal iron studies with leukocytosis
Low ferritin with microcytic anemia
High ferritin with macrocytosis
Elevated platelet count with high ferritin only
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Which histologic subtype is characterized by signet-ring cells?
GIST (gastrointestinal stromal tumor)
MALT lymphoma
Intestinal-type gastric adenocarcinoma
Diffuse-type gastric adenocarcinoma
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Which hereditary syndrome is most strongly associated with diffuse gastric cancer?
Lynch syndrome due to MSH2 mutation only
Multiple endocrine neoplasia type 1
Li-Fraumeni syndrome
Hereditary diffuse gastric cancer due to CDH1 mutation
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Which first-line systemic therapy is commonly used for resectable, fit patients with locally advanced gastric cancer in many regions?
Hydroxyurea only
Perioperative FLOT (5-FU, leucovorin, oxaliplatin, docetaxel)
Single-agent prednisone
Imatinib monotherapy
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Which surgical approach is preferred for a distal (antral) gastric adenocarcinoma amenable to resection?
Pancreatectomy alone
Esophagectomy only
Subtotal (distal) gastrectomy with lymphadenectomy
Total colectomy
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Which finding best defines linitis plastica?
Multiple superficial aphthous ulcers
A single pedunculated polyp in the antrum
A circumferential esophageal ring
Diffuse gastric wall thickening causing a rigid, leather-bottle stomach
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Positive peritoneal cytology without visible implants can upstage gastric cancer to metastatic disease in many staging systems.
True
False
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Prophylactic total gastrectomy may be considered in confirmed CDH1 mutation carriers after counseling.
True
False
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Signet-ring cell carcinomas often have an E-cadherin dysfunction related to CDH1.
True
False
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Peritoneal carcinomatosis from gastric cancer may benefit from cytoreductive surgery and HIPEC in all patients as standard of care.
False
True
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Learning Outcomes

  1. Identify early symptoms and risk factors of stomach cancer
  2. Analyse diagnostic procedures and staging criteria
  3. Evaluate treatment options and prognosis factors
  4. Demonstrate understanding of prevention and screening guidelines
  5. Apply pathophysiology concepts to gastric cancer cases
  6. Master key statistics and epidemiological trends

Cheat Sheet

  1. Recognize early symptoms - Spotting persistent indigestion, stomach discomfort, nausea, and unexpected weight loss gives you a head start on tackling stomach cancer. Learning these telltale signs empowers you to seek timely medical advice.
  2. Understand risk factors - Knowing that Helicobacter pylori infection, diets rich in salty or smoked foods, smoking, and family history can raise your risk helps you make savvy lifestyle choices. With these insights, you'll be a prevention pro.
  3. Familiarize with diagnostics - Diagnostic tools like endoscopy and biopsy are your detective duo for confirming stomach cancer. Understanding how these tests work gives you confidence in the journey ahead.
  4. Learn the TNM staging system - The TNM system assesses tumor size (T), lymph node involvement (N), and metastasis (M) to map out the cancer's reach. Accurate staging is your roadmap to effective treatment planning.
  5. Explore treatment options - From surgery and chemotherapy to radiation and targeted therapies, treatment choices depend on your cancer's stage and location. Knowing the playbook helps you team up with your healthcare squad.
  6. Understand prognosis factors - Factors like cancer stage at diagnosis, overall health, and treatment response can shape the outcome and survival rates. Early detection and a healthy lifestyle often swing things in your favor.
  7. Review prevention strategies - Eradicating H. pylori, tweaking your diet, and kicking the smoking habit are simple steps that can lower your stomach cancer risk. Small changes today can lead to big wins tomorrow.
  8. Dive into pathophysiology - Chronic inflammation from H. pylori infection can spark cellular changes that pave the way for cancerous growth. Grasping these mechanisms deepens your understanding of disease progression.
  9. Know key statistics - Stomach cancer ranks as the fifth most common cancer worldwide, with millions of new cases each year. These stats highlight why awareness and research are vital for global health.
  10. Stay updated on trends - Thanks to better food preservation and dropping H. pylori rates, stomach cancer incidence is falling in many regions. Tracking these shifts helps public health experts tailor prevention efforts.
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