Unlock hundreds more features
Save your Quiz to the Dashboard
View and Export Results
Use AI to Create Quizzes and Analyse Results

OR
Sign inSign in with Facebook
Sign inSign in with Google
Quizzes > Science

Benzene Derivative Crossword: Quick Practice Quiz

Quick, free benzene derivatives crossword quiz. Instant results.

Editorial: Review CompletedCreated By: Rikrdo CeliUpdated Aug 23, 2025
Difficulty: Moderate
2-5mins
Learning OutcomesCheat Sheet
Paper art coral backdrop with benzene ring crossword and molecular icons for free benzene derivative quiz

This quiz helps you solve benzene derivative crossword clues and recall common aromatic substituents. Use quick prompts to practice names, spot patterns, and check reasoning, then sharpen fundamentals with our aromatic compounds quiz and build naming skills in the chemical nomenclature quiz. Want more ring reactions? Try the benzene electrophilic substitution quiz for targeted EAS practice.

This benzene derivative has a single methyl group attached to the ring.
Toluene
Phenol
Ethylbenzene
Aniline
Toluene, also known as methylbenzene, is benzene with one methyl substituent. It is a common solvent and precursor in organic synthesis. The methyl group increases the electron density of the aromatic ring by donation through hyperconjugation.
The simplest aromatic compound with a nitro substituent on the benzene ring is called what?
Aniline
Phenol
Nitrotoluene
Nitrobenzene
Nitrobenzene is benzene with one nitro group and is the simplest nitro-substituted aromatic. It is a pale yellow liquid used in the production of aniline. The nitro group is a strong electron-withdrawing substituent that deactivates the ring for electrophilic aromatic substitution.
Also known as phenylamine, this benzene derivative contains an amino group.
Phenol
Aniline
Nitrobenzene
Toluene
Aniline is benzene with an amino (-NH2) substituent and is also called phenylamine. It's a key intermediate in dyes, plastics, and pharmaceuticals. The amino group is strongly activating and directs substitution to ortho and para positions.
This compound is benzene with a carboxylic acid substituent.
Benzoic acid
Benzaldehyde
Phenol
Acetophenone
Benzoic acid is the simplest aromatic carboxylic acid, with formula C6H5COOH. It's used as a food preservative and intermediate in organic synthesis. The carboxyl group deactivates the ring toward further electrophilic substitution.
This benzene derivative features an - OH group and is used as a disinfectant.
Phenol
Nitrobenzene
Aniline
Benzyl alcohol
Phenol, also known as carbolic acid, is benzene with a hydroxyl group. It's widely used as a disinfectant and antiseptic. The - OH makes it more acidic than aliphatic alcohols due to resonance stabilization of its conjugate base.
This derivative contains an aldehyde functional group on the benzene ring.
Acetophenone
Phenol
Benzaldehyde
Benzoic acid
Benzaldehyde is benzene with a formyl (-CHO) substituent. It's responsible for the almond scent in bitter almonds and used in flavorings and fragrances. The aldehyde group is an electron-withdrawing group that influences ring reactivity.
Also known as methyl phenyl ketone, this compound is a benzene ring with an acetyl group.
Ethylbenzene
Acetophenone
Benzophenone
Acetone
Acetophenone is benzene with an acetyl (-COCH3) substituent, also called methyl phenyl ketone. It is used as a fragrance and as a precursor in organic synthesis. The ketone group is moderately deactivating and directs substitution to meta positions.
Benzene with two methyl groups at positions 1 and 4 is called _____.
Cumene
o-Xylene
m-Xylene
p-Xylene
p-Xylene has two methyl groups at the para (1,4) positions on benzene. It's one of three xylene isomers and is used in the production of terephthalic acid. The methyl substituents are ortho/para directors in electrophilic substitution.
This benzene derivative has both amino and nitro groups at para positions, used in dye synthesis.
Naphthalene
o-Nitrophenol
p-Aminobenzoic acid
p-Nitroaniline
p-Nitroaniline has an amino group at position 1 and a nitro group at position 4 on the benzene ring. It's a key intermediate in the manufacture of dyes and pigments. The nitro group is strongly deactivating, while the amino group is strongly activating, affecting reactivity patterns.
This compound has a sulfonic acid group attached to benzene and is used in detergents.
Toluene sulfonic acid
Benzenesulfonic acid
Sulfanilic acid
Phenolsulfonic acid
Benzenesulfonic acid is benzene with a - SO3H group. It's a strong acid and an intermediate in the manufacture of detergents and dyes. Sulfonic acids are strongly deactivating and meta-directing in electrophilic substitution.
This coloring agent derivative of benzene has three nitro groups.
Trinitrophenol
Triiodobenzene
Trinitrotoluene (TNT)
Nitrobenzene
Trinitrotoluene (TNT) is methylbenzene substituted with three nitro groups at the 2,4,6 positions. It's best known as a high explosive and colored yellow. The strong electron-withdrawing nitro groups make the ring extremely deactivated.
This benzene derivative contains both - OH and - COOH substituents, known as salicylic acid.
Benzoic acid
o-Hydroxybenzoic acid
Salicylic acid
p-Hydroxybenzoic acid
Salicylic acid is o-hydroxybenzoic acid, with a hydroxyl at position 2 and a carboxyl at 1. It's used in acne treatments and as a precursor to aspirin. The proximity of - OH and - COOH allows intramolecular hydrogen bonding, affecting acidity.
This heterocyclic benzene analog has nitrogen replacing one carbon in the ring and is used as a solvent.
Pyrrole
Pyridine
Thiophene
Furan
Pyridine is a six-membered aromatic ring with one nitrogen atom replacing a CH group. It's a polar solvent with a distinct fishy smell, used widely in organic chemistry. The nitrogen lone pair does not participate in the aromatic sextet, preserving aromaticity.
This benzene derivative has an - OH group at position 1 and a - NO2 at position 4, used as an intermediate in pharmaceuticals.
o-Nitrophenol
Phenol
p-Nitrophenol
m-Nitrophenol
p-Nitrophenol has hydroxyl and nitro groups at the para positions. It's used as an intermediate in the manufacture of analgesics and dyes. The nitro group deactivates the ring and withdraws electron density, affecting acidity of the phenolic - OH.
0
{"name":"This benzene derivative has a single methyl group attached to the ring.", "url":"https://www.quiz-maker.com/QPREVIEW","txt":"This benzene derivative has a single methyl group attached to the ring., The simplest aromatic compound with a nitro substituent on the benzene ring is called what?, Also known as phenylamine, this benzene derivative contains an amino group.","img":"https://www.quiz-maker.com/3012/images/ogquiz.png"}

Study Outcomes

  1. Identify Benzene Substituents -

    Recognize common functional groups and substituents on a benzene ring when presented with crossword-style clues.

  2. Analyze Clue Context -

    Decode crossword clues to infer the correct benzene derivative based on chemical properties and naming hints.

  3. Apply IUPAC Naming -

    Use systematic nomenclature rules to accurately name benzene derivatives identified in the quiz.

  4. Differentiate Positional Isomers -

    Distinguish between ortho, meta, and para configurations for substituted benzene compounds.

  5. Reinforce Aromatic Chemistry Concepts -

    Solidify understanding of benzene derivative terminology and substituent effects through interactive trivia questions.

  6. Evaluate Quiz Performance -

    Assess your aromatic chemistry IQ and identify areas for further study or review after completing the benzene derivative crossword clue quiz.

Cheat Sheet

  1. IUPAC Numbering and Substitution Patterns -

    Follow IUPAC rules to assign the lowest possible set of locants for substituents on the benzene ring (IUPAC, 2013). Remember the ortho-meta-para mnemonic: 1,2-o; 1,3-m; 1,4-p to quickly map positions during crossword solving.

  2. Activating vs. Deactivating Substituents -

    Activating groups (e.g., - OH, - OCH₃) donate electron density via resonance or induction and direct ortho/para substitution, while deactivating groups (e.g., - NO₂, - CF₃) withdraw electrons and favor meta positions (Clayden et al., 2012). Knowing this distinction helps predict reactivity patterns and solve clues about directing effects.

  3. Common Substituent Prefixes and Examples -

    Memorize key prefixes: methyl (CH₃ - ), ethyl (C₂H₅ - ), nitro ( - NO₂), chloro ( - Cl), bromo ( - Br), and phenyl ( - C₆H₅) as listed in the Merck Index. These building blocks frequently appear in crossword clues, so recognizing shorthand like "toluene" for methylbenzene speeds up identification.

  4. Alphabetical Order in Multi-Substituted Names -

    When naming di- or tri-substituted benzenes, list substituents alphabetically (e.g., 1-bromo-4-nitrobenzene, Br before N) and ignore multiplicative prefixes (di-, tri-) in the order (IUPAC, 2013). This rule ensures you land on the correct systematic name every time.

  5. Resonance and Directing Effects -

    Sketch resonance structures to visualize how substituents either donate (+R) or withdraw ( - I) electrons, influencing ring activation and orientation (University of California, Berkeley). This mental exercise doubles as a powerful mnemonic for predicting where new groups will attach.

Make a Quiz (FREE) Copy & Edit This Quiz Create a Quiz with AI

Chemistry Quizzes

Powered by: Quiz Maker