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Quizzes > Health & Medicine

Cardiovascular Pharmacology: the cardiovascular system test

Quick cardiovascular system quiz to test your knowledge. Instant results.

Editorial: Review CompletedCreated By: Thupten DremaUpdated Aug 23, 2025
Difficulty: Moderate
2-5mins
Learning OutcomesCheat Sheet
Paper art heart and blood vessels on sky blue background with free Pharmacology Made Easy cardiovascular quiz challenge

This quiz helps you practice cardiovascular pharmacology-drug actions, uses, and safety-so you can check your understanding before a test or shift. Try related prep like the NCLEX-RN perfusion quiz, brush up on rhythms with a free ecg test, or track patterns with a telemetry quiz. Take your time, then see which topics to review next.

Which drug class lowers blood pressure by preventing the conversion of angiotensin I to angiotensin II?
Direct renin inhibitors
ACE inhibitors
ARBs
Beta-1 selective blockers
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Dihydropyridine calcium channel blockers primarily act on vascular smooth muscle to reduce peripheral resistance.
True
False
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Which adverse effect is most characteristic of spironolactone compared with eplerenone?
Constipation
Hyperkalemia
Hypokalemia
Gynecomastia
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Nitrates relieve angina primarily by decreasing preload through venodilation.
False
True
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Which lipid-lowering agent most effectively reduces LDL cholesterol levels?
Niacin
High-intensity statins
Omega-3 fatty acids
Bile acid sequestrants
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Thiazide diuretics increase calcium reabsorption in the distal convoluted tubule.
False
True
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Which beta-blocker also has alpha-1 blocking activity useful in heart failure with reduced ejection fraction?
Metoprolol tartrate
Carvedilol
Esmolol
Atenolol
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Clopidogrel requires bioactivation via CYP2C19 to exert its antiplatelet effect.
False
True
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Which antiarrhythmic is associated with pulmonary fibrosis, thyroid dysfunction, corneal deposits, and blue-gray skin discoloration?
Flecainide
Amiodarone
Lidocaine
Sotalol
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Non-dihydropyridine calcium channel blockers are first-line agents for systolic heart failure exacerbations.
False
True
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Which drug combination is specifically beneficial in HFrEF for self-identified Black patients to reduce mortality?
Hydralazine plus isosorbide dinitrate
Spironolactone plus hydrochlorothiazide
Verapamil plus digoxin
Amlodipine plus atenolol
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Loop diuretics tend to cause hypocalcemia, whereas thiazides can cause hypercalcemia.
True
False
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Which medication can cause cyanide toxicity, especially with prolonged high-dose infusion or renal impairment?
Nicardipine
Fenoldopam
Sodium nitroprusside
Nitroglycerin
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Which agent directly inhibits the funny current (If) in the SA node to lower heart rate without lowering blood pressure?
Digoxin
Diltiazem
Ranolazine
Ivabradine
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Which antiarrhythmic class Ic drug is contraindicated in patients with structural heart disease due to proarrhythmic risk?
Procainamide
Mexiletine
Amiodarone
Flecainide
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Which combination has the highest risk of life-threatening bradycardia and AV block?
Atorvastatin plus ezetimibe
Amlodipine plus nitrate
Verapamil plus beta-blocker
Hydrochlorothiazide plus losartan
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Furosemide coadministration with aminoglycosides increases the risk of ototoxicity.
True
False
undefined
Statins with short half-lives are optimally dosed in the evening to align with nocturnal hepatic cholesterol synthesis.
True
False
undefined
Sacubitril-valsartan increases bradykinin levels through neprilysin inhibition, increasing the risk of angioedema, especially with ACE inhibitor coadministration.
True
False
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Prasugrel is contraindicated in patients with a history of stroke or TIA due to bleeding risk.
False
True
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0

Study Outcomes

  1. Identify Cardiovascular Drug Classes -

    Differentiate the major heart and vessel drug categories by their mechanisms of action and therapeutic uses.

  2. Evaluate Mechanisms and Adverse Effects -

    Analyze pharmacokinetics and typical side effect profiles to predict patient responses and manage risks.

  3. Apply Dosing and Monitoring Principles -

    Determine safe dosing regimens and monitoring parameters to optimize outcomes for cardiovascular medications.

  4. Assess Clinical Scenarios -

    Interpret patient case studies to select appropriate pharmacological interventions for conditions such as hypertension, heart failure, and arrhythmias.

  5. Develop Test-Taking Strategies -

    Utilize targeted pharmacology cardiovascular quiz practice to boost confidence and readiness for the pharmacology made easy 5.0 the cardiovascular system test.

Cheat Sheet

  1. RAAS Inhibitors (ACE Inhibitors & ARBs) -

    ACE inhibitors ( - pril) block the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and aldosterone-mediated volume expansion, while ARBs ( - sartan) selectively block AT1 receptors to achieve similar hemodynamic effects. A mnemonic "PRIL for ACE Inhibition, SARTAN for Ang II Receptor ANTagonism" helps anchor their mechanisms (Source: American Heart Association).

  2. Beta-Blocker Selectivity & Mnemonics -

    Beta-blockers vary in β1-selectivity; metoprolol and atenolol preferentially target cardiac β1 receptors, whereas propranolol blocks both β1 and β2 receptors - critical for asthma patients. Remember "AMEBA" (Atenolol, Metoprolol, Esmolol, Bisoprolol, Acebutolol) for cardioselective agents to ace your pharmacology cardiovascular quiz (Source: Goodman & Gilman's).

  3. Calcium Channel Blocker Classes -

    Non-dihydropyridines (verapamil, diltiazem) reduce heart rate and contractility, while dihydropyridines (amlodipine, nifedipine) primarily vasodilate peripheral arteries. Use the "Very Nice Drugs" mnemonic (Verapamil, Nifedipine, Diltiazem) to quickly recall each subclass's clinical effects (Source: UpToDate).

  4. Frank-Starling Law & Stroke Volume -

    The Frank-Starling curve describes how stroke volume (SV) increases with end-diastolic volume (EDV) up to an optimal point, summarized by SV = EDV - end-systolic volume (ESV). Understanding this preload-SV relationship is crucial for questions on volume status and heart failure management (Source: Guyton & Hall Physiology).

  5. Vaughan Williams Antiarrhythmic Classification -

    Antiarrhythmics are grouped into four classes - sodium channel blockers (I), β-blockers (II), potassium channel blockers (III), and calcium channel blockers (IV) - using the mnemonic "No Bad Boy Keeps Clean." When prepping for the pharmacology made easy 5.0 the cardiovascular system test or a heart medication quiz, this system helps you swiftly categorize agents like lidocaine, propranolol, amiodarone, and verapamil (Source: American College of Cardiology).

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