Pediactic. kb 1

Pediatric Health Knowledge Quiz
Test your knowledge on pediatric health concepts with this comprehensive quiz designed for healthcare professionals and students alike.
Whether you’re preparing for an examination or simply want to refresh your understanding, this quiz features:
- 150 thought-provoking questions
- Relevant multiple-choice options
- A variety of pediatric topics

1. Two weeks after a viral syndrome, a 9-year-old boy presents to your clinic with a complaint of several days of weakness of his mouth. In addition to the drooping of the left side of his mouth, you note that he is unable to completely shut his left eye. His smile is asymmetric, but his examination is otherwise normal. Which of the following is the most likely diagnosis?
A. Guillain-Barre̝ syndrome
B. Botulism
C. Cerebral vascular accident
D. Brainstem tumor
E. Bell palsy
2. An infant can regard his parent’s face, follow to the midline, lift his head from the examining table, smile spontaneously, and respond to a bell. He does not yet regard his own hand, follow past the midline, nor lift his head to a 45° angle off the examining table. Which of the following is the most likely age of the infant?
A. 1 month
B. 3 months
C. 6 months
D. 9 months
E. 12 months
 3. A child is brought to your clinic for a routine examination. She can put on a T-shirt but requires a bit of help dressing otherwise. She can copy a circle well but has diffic ulty in copying a square. Her speech is understandable and she knows four colors. She balances proudly on each foot for 2 seconds but is unable to hold the stance for 5 seconds. Which of the following is the most likely age of this child?
A. 1 year
B. 2 years
C. 3 years
D. 4 years
E. 5 years

4. A 4-year-old girl is noticed by her grandmother to have a limp and a some-what swollen left knee. The parents report that the patient occasionally com- plains of pain in that knee. An ophthalmologic examination reveals findings as depicted in the photograph. Which of the following conditions is most likely to be associated with these findings?
A. Juvenile rheumatoid arthritis
B. Slipped capital femoral epiphysis
C. Henoch-Schönlein purpura
D. Legg-Calve̝-Perthes disease
E. Osgood-Schlatter disease

5. A previously healthy 4-year-old child pictured below presents to the emergency room (ER) with a 2-day history of a brightly erythematous rash and temperature of 40°C (104°F). The exquisitely tender, generalized rash is worse in the flexural and perioral areas. The child is admitted and over the next day develops crusting and fissuring around the eyes, mouth, and nose. The desquamation of skin shown in the photograph occurs with gentle traction. Which of the following is the most likely diagnosis?
A. Epidermolysis bullosa
B. Staphylococcal scalded skin syndrome
C. Erythema multiforme
D. Drug eruption
E. Scarlet fever
6. A patient comes to your office for a hospital follow-up. You had sent him to the hospital 3 weeks earlier for persistent fevers but no other symptoms; he was diagnosed with endocarditis and is  currently being treated appropriately. Advice to this family should now include which following?
Restrict the child from all strenuous activities.
Give the child a no-salt-added diet.
Provide the child with antibiotic prophylaxis for dental procedures
Test all family members in the home with repeated blood cultures. 
Avoid allowing the child to get upset or agitated.
7. A mother calls you on the telephone and says that your 4-year-old son bit the hand of her 2- year-old son 48 hours previously. The area around the injury has become red, indurated, and swollen, and he has a temperature of 39.4°C (103°F). Which of the following is the most appropriate response?
A)	Arrange for a plastic  surgery consultation  at the  next available   appointment.
B)	Admit the child to the hospital immediately for surgical debridement and antibiotic treatment.
C)	Prescribe penicillin over the telephone and have the mother apply warm soaks for 15 minutes  four times  a day.
D)	Suggest purchase of bacitracin ointment  to apply  to the lesion  three times a   day.
E)	See the patient  in  the ER to suture the laceration.

8) The adolescent shown presents with a 14-day history of multiple oval lesions over her back. The rash began with a single lesion over the lower abdomen (A); the other lesions developed over the next days (B). These lesions are slightly pruritic. Which of the following is the most likely diagnosis?
A)	Contact dermatitis
B)	Pityriasis  rosea
C)	Seborrheic  dermatitis
D)	Lichen planus
E)	Psoriasis

9) A chubby 6-month-old baby boy is brought to the clinic by his father. His father is concerned that his penis is too small (see photograph). The child is at the 95% for weight and the 50% for length; he has been developing normally and has had no medical problems. Which of the following is the most appropriate first step in management of this child?
A)	Surgical  consultation
B)	Evaluation  of penile  length  after retracting the skin  and fat lateral to the penile  shaft
C)	Ultrasound  for uterus and ovaries
D)	Weight  loss
E)	Serum testosterone levels

10) A previously healthy 5-year-old boy has a 1-day history of low-grade fever, colicky abdominal pain, and a rash. He is well-appearing and alert. His vital signs, other than a temperature of 38°C (100.5°F) are completely normal. A diffuse, erythematous, maculopapular, and petechial rash is present on his buttocks and lower extremities, as shown in the photograph. He has no localized abdominal tenderness or rebound; bowel sounds are active. Laboratory data demonstrate i) Urinalysis: 30 red blood cells (RBCs) per high-powered field, 2+ protein Stool: Guaiac positive Platelet count: 135,000/μL ii) These findings are most consistent with which of the following?
A)     Anaphylactoid  purpura
B)	Meningococcemia
C)	Child  abuse
D)	Leukemia
E)	Hemophilia   B

11) A 4-month-old baby boy arrives to the ER cold and stiff. The parents report that he had been healthy and that they put him to bed as usual for the night at the regular time. When they next saw him, in the morning, he was dead. Physical examination is uninformative. A film from a routine skeletal survey is shown below. Which of the following is the most likely diagnosis?
A)	Scurvy
B)	Congenital  syphilis
C)	Sudden  infant  death syndrome (SIDS)
D)	Osteogenesis imperfecta
E)	Abuse

12) A 6-year-old boy is often teased at school because he has stooled in his underwear almost daily for the last 3 months. He was toilet trained at 2 years of age without difficulty, but over the last 2 years he had developed ongoing constipation. His family is frustrated because they cannot believe him when he says ―I didn’t know I had to go.‖ He is otherwise normal; school is going well, and his home life is stable. His only finding on examination is significant for stool in the rectalvault. The plain radiograph of his abdomen is shown. Initial management of this problem should include which of the following?
A)	Barium  enema and rectal biopsy
B)	Family  counseling
C)	Time-out  when he stools  in  his underwear
D)	Clear fecal impaction  and short-term stool softener use
E)	Daily  enemas for 4 weeks

13) A 2-year-old child presents to the office with a paternal complaint of “bowlegs.” The girl has always had bowlegs; her previous pediatrician told the family she would grow out of it. Now, however, it seems to be worsening. Her weight is greater than 95% for age, and she has i) significant bowing out of her legs and internal tibial torsion; otherwise, her examination is normal. A radiograph of her lower leg is shown. Which of the following is the most likely diagnosis?
B)	Osgood-Schlatter  disease
C)	Physiologic   genu varum
D)	Slipped   capital femoral epiphysis
E)	Legg-Calvé-Perthes disease
F)	Blount  disease
14)	A very concerned mother brings a 2-year-old child to your office because of two episodes of a brief, shrill cry followed  by a prolonged  expiration  and apnea. You have been following  this child  in  your  practice since birth  and know the child  to be a product  of a normal pregnancy and delivery,  to be growing  and developing  normally,  and to have no chronic  medical  problems.  The first  episode  occurred immediately  after the mother  refused to give  the child some juice; the child became cyanotic, unconscious, and had generalized clonic jerks. A few moments later the child  awakened and had no residual effects. The most recent episode  (identical in nature) occurred at the grocery store when the child’s father refused to purchase a toy for her. Your physical examination reveals a delightful child without unexpected physical examination  findings.   Which of the  following   is  the  most likely  diagnosis?
A)	Seizure  disorder
B)	Drug ingestion
C)	Hyperactivity  with  attention deficit
D)	Pervasive development  disorder
E)	Breath-holding  spell
15)	A 10-year-old  child  arrives  with  the complaint   of new-onset bed-wetting.  He has had no fever, his urine culture is negative, and he has had no new stresses in his  life.  He is  well above the 95th percentile  for weight as is  much of his  family.  Which  of the following  is  most helpful  in  making  a diagnosis
A)	Fasting  plasma  glucose  of 135 mg/dL
B)	Random plasma  glucose  of 170 mg/dL
C)	Two-hour glucose  during  glucose  tolerance  test of 165 mg/dL
D)	Acanthosis  nigricans  on  the neck
E)	Symptoms  alone  are enough to make  the diagnosis
16)	You are called to the ER to see one of your patients. The father of this 14-year-old mildly  retarded child says that he found the child about 20 minutes ago in the neighbor’s garden shed with an unknown substance in his mouth. The child first  had a headache, but then became agitated and confused; while you are talking to the father in the ER the child begins to have a seizure and dysrhythmia  on the cardiac monitor.  The blood  gas demonstrates a severe  metabolic  acidosis.  Which  of the following   agents is  most likely   the culprit?
A)	Organophosphate
B)	Chlorophenothane   (DDT)
C)	Sodium  cyanide
D)	Warfarin
E)	Paraquat

17) The mother of a 3-day-old infant brings her child to your office for an early follow-up visit. The mom notes that the child has been eating well, has had no temperature instability, and stools and urinates well. She notes that over the previous 3 days the child has had a progressive rash on the face as pictured here. Which of the following is the most likely diagnosis?
A)	Herpes
B)	Neonatal acne
C)	Milia
D)	Seborrheic  dermatitis
E)	Eczema

18) A 2-year-old child (A) presents with a 4-day history of a rash limited to the feet and ankles. The papular rash is both pruritic and erythematous. The 3-month-old sibling of this patient has similar lesions also involving the head and neck. The most appropriate treatment for this condition includes which of the following?
A)	Coal-tar soap
B)	Permethrin
C)	Hydrocortisone  cream
D)	Emollients
E)	Topical  antifungal cream

19) An 8-hour-old infant develops increased respiratory distress, hypothermia, and hypotension. A complete blood count (CBC) demonstrates a white blood cell (WBC) count of 2500/μL with 80% bands. The chest radiograph is shown below. Which of the following is the most likely diagnosis?
A)	Congenital  syphilis
B)	Diaphragmatic  hernia
C)	Group  B streptococcalpneumonia
D)	Transient tachypnea of  the  newborn
E)	Chlamydial   pneumonia
20)	A 16-year-old arrives to your office soon after beginning basketball season. He states that he has had progressive pain  in  his  knees. A physical  examination  reveals, in  addition to tenderness, a swollen and prominent tibial tubercle. Radiographs of the area are unremarkable.  Which  of the following   is  the  most likely  diagnosis?
A)	Osgood-Schlatter  disease
B)	Popliteal cyst
C)	Slipped   capital femoral epiphysis
D)	Legg-Calvé-Perthes disease
E)	Gonococcal arthritis

21) You are performing a well-child examination on the 1-year-old child shown in the picture. For this particular problem, which of the following is the most appropriate next step in management?
A)	Patch the eye with  the greater refractive error
B)	Patch the eye that deviates
C)	Defer patching or ophthalmologic examination  until  the child  is  older  and better able  to cooperate
D)	Reassure the mother that he  will  outgrow it
E)	Refer immediately   to ophthalmology
22)	You are seeing a 2-year-old child, brought by his father for a well-child examination. In  providing   age-appropriate anticipatory  guidance,  you should  tell him  which of the   following?
A)	He should set his water heater to 71°C (160°F) to ensure the sterility of dishes and clothes,  thereby decreasing the  risk of infections.
B)	Milk  should  be switched from whole  to skim or low   fat.
C)	Continue  rear facing car seats.
D)	Purchase a bed alarm to assist with  the child’s  nocturnal enuresis.
E)	Teach the child to swim so that the parents have the ability to allow the child to be alone  in pools.
23)	A child can walk well holding on to furniture but  is  slightly  wobbly  when walking  alone. She uses a neat pincer grasp to pick up a pellet, and she can release a cube into  a cup after it has been demonstrated to her. She tries to build a tower of two cubes with variable success. She is most likely   at which of the following   age?
A)	2 months
B)	4 months
C)	6 months
D)	9 months
E)	1 year
24)	You are called by  a general practitioner  to consult  on a patient admit-  ted to the hospital  4 days ago. The patient is a 7-month-old white boy with poor weight gain  for the past 3 months,  who has not gained weight in the hospital despite seemingly adequate nutrition.  You take a detailed  diet  his- tory  from his  foster mother, and the amounts  of formula  and baby  food intake seem appropriate for age. Physical examination reveals an active, alert infant with a strong suck reflex who appears wasted. You note generalized lymphadenopathy with hepatomegaly. In addition, you find a severe case of oral candidiasis that apparently has been resistant to treatment. Which of the following  is  the most  appropriate next step in  the  evaluation  or treatment of this  child?
A)	Increase caloric intake  because this  is  probably  a case of underfeeding.
B)	Order human immunodeficiency   virus  (HIV) polymerase  chain reaction (PCR).Testing  because this  is  likely   the presentation of congenitally  acquired  HIV.
C)	Draw blood  cultures  because this  could  be sepsis.
D)	Perform a sweat chloride  test because this  is  probably  cystic fibrosis.
E)	Send stool for fecalfat because this  is  probably  a malabsorption   syndrome.

25) A 5-year-old boy presents with the severe rash shown in the photographs. The rash is pruritic, and it is especially intense in the flexural areas. The mother reports that the symptoms began in infancy (when it also involved the face) and that her 6-month-old child has similar symptoms. Which of the following is the most appropriate treatment of this condition?
A)	Coal-tar soaps and shampoo
B)	Topical  antifungal cream
C)	Ultraviolet  light   therapy
D)	Moisturizers   and topical steroids
E)	Topical antibiotics
26)	A 1-year-old presents for a well-child checkup, but the parents are concerned about giving the child  his  immunizations.   Which  of the following  is  a true contraindication  to  the administration of the fourth DTaP (diphtheria and tetanus      toxoid and acellular pertussis) vaccine?
A)	Child  is  currently on  amoxicillin   for an otitis  media
B)	Positive  family  history  of adverse reactions to DTaP vaccine
C)	A past history  of infantile  spasms
D)	Child  is  currently febrile  to 39°C (102.2°F)
E)	Prolonged  seizures 6 days after the  last DTaP vaccine
27)	A mother arrives to the clinic with her three children (ages 2 months, 18 months, and 36 months). The 18-month-old has an intensely pruritic scalp, especially in the occipital  region,  with 0.5-mm lesions noted at the base of hair shafts, as shown in the picture. Which of the following   therapies should  be  avoided  in  this situation?
A)	Treatment of all household  contacts with  1% lindane   (Kwell)
B)	Use of 1:1  vinegar-water rinse for hair for nit   removal
C)	Washing  of all clothing  and bedding  in  very hot  water
D)	Replacement of all commonly   used brushes
E)	Advice  to the mother that treatment will  again  be necessary in 7 to 10 days
28)	A 2-year-old boy has been vomiting intermittently  for 3 weeks and has been irritable,  listless, and anorectic. His use of language  has regressed to speaking  single  words. In your evaluation of this  patient, which  of the  following   is  the  most reasonable diagnosis   to consider?
A)	Expanding  epidural  hematoma
B)	Herpes simplex  virus  (HSV) encephalitis
C)	Tuberculous  meningitis
D)	Food allergy
E)	Bacterial meningitis
29)	You find a discrete, whitish polyp that extends through the tympanic  membrane in  a child with  a history  of recurrent otitis  media.  This  most likely   represents which of the following?
A)	A cholesteatoma
B)	Tympanosclerosis
C)	Acute otitis  media  with  perforation  and drainage
D)	Dislocation  of the  malleus  from its  insertion  in  the  tympanic membrane
E)	Excessive  cerumen production
30)	An 8-month-old infant arrives to the emergency department (ED) with a 2-day history of diarrhea and poor fluid   intake. Your quick  examination  reveals a lethargic  child;   his  heart rate is 180 beats per minute, his respiratory rate is 30 breaths per minute, and his blood  pressure is  low for age. He has poor skin turgor, 5-second capillary refill,  and cool extremities.  Which  of the  following   fluids  is  most appropriate  management for his  condition?
A)	Dextrose 5% in  1/4 normal  saline  (D5 1/4 NS)
B)	Dextrose 5% in  1/2 normal  saline  (D5 1/2 NS)
C)	Normal saline
D)	Whole  blood
E)	Dextrose 10% in  water (D10W)
31)	During the examination of a 2-month-old infant, you note  that the infant’s umbilical  cord is  still  firmly  attached. This  finding   prompts  you  to suspect which of the following?
A)	Occult omphalocele
B)	Leukocyte  adhesion deficiency
C)	IgG subclass  deficiency
D)	Umbilical  granuloma
E)	Persistent urachus (urachal cyst)
32)	You are seeing an established patient, a 4-year-old girl brought in by her mother for vaginal itching  and irritation.   She is  toilet  trained and has not  complained  of frequency or urgency, nor has she noted any blood in her urine. Her mother noted she has been afebrile and has not complained of abdominal pain. Mom denies the risk  of inappropriate  contact; the girl  also  denies anyone “touching her there.” Your physical examination  of the perineum is  significant  for the lack of foul odor or discharge. You do note some erythema of the vulvar area but no evidence of trauma. Which  of the following   is  the most appropriate  course of  action?
A)	Refer to pediatric gynecology for removal under anesthesia of a suspected foreign body  in  the vagina.
B)	Counsel mother to stop giving the girl bubble baths, have the girl wear only cotton underwear, and improve  hygiene.  
C)	Refer to social services for suspected physical or sexual  abuse.
D)	Swab for gonorrhea  and plate  on  chocolate agar, and send urine  for Chlamydia.
E)	Treat with an antifungal  cream for suspected yeast infection.
33)	A 20-month-old   child  is  brought  to the ED because of fever and irritability   and refusal to move his right lower extremity. Physical examination reveals a swollen  and tender right  knee that resists passive motion. Which of the following  is  the most likely  to yield  the diagnosis  in  this  patient?
A)	Examination   of joint  fluid
B)	X-ray of the knee
C)	Erythrocyte  sedimentation  rate (ESR)
D)	CBC and differential
E)	Blood  culture
34)	A 14-year-old high school student arrives to your clinic for well-child care. In reviewing his records you determine that his most recent immunization for tetanus was at 4 years of age. Which  of the following   should  you recommend?
A)	Tetanus toxoid
B)	Adult  tetanus and diphtheria  toxoid  (Td)
C)	Diphtheria  toxoid,  whole  cell pertussis, and tetanus toxoid   (DPT) booster
D)	Tetanus toxoid  and tetanus immune  globulin
E)	Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine adsorbed (Tdap) 
 35)	A 5-year-old boy is brought into the ER immediately after an unfortunate altercation with a neighbor’s  immunized   Chihuahua  that occurred while  the child  was attempting  to dress the dog as a superhero. The fully immunized child  has a small,  irregular,  superficial laceration on  his right forearm that has stopped bleeding. His neuromuscular  examination  is  completely normal,  and his  perfusion  is  intact. Management should  include  which of the  following?
A)	Irrigation  and antimicrobial   prophylaxis
B)	Tetanus booster immunization   and tetanus toxoid  in  the  wound
C)	Copious  irrigation
D)	Primary rabies  vaccination  for the child
E)	Destruction of the  dog and examination  of brain  tissue  for rabies
36)	Aunt Mary is helping her family move to a new apartment. During the confusion, 3-year-old Jimmy is noted to become lethargic.  The  contents of Aunt Mary’s purse are strewn about on the floor. In the ER, the lethargic  Jimmy  is  found to have miosis,  bradycardia, and  hypotension.  He develops  apnea, respiratory depression,  and has to be intubated.  His condition  would  most  likely   benefit from which  of the following  therapies?
A)	Deferoxamine
B)	Pediatric  intensive  care unit  (PICU) support and trial  of naloxone
C)	N-acetylcysteine  (Mucomyst)
D)	Atropine
E)	Dimercaptosuccinic  acid (DMSA, succimer)
37)	As a city public health officer, you have been charged with the task of screening high-risk children  for lead poisoning.   Which  of the following   is  the  best screen for this purpose?
A)	Careful physical examination  of each infant  and child
B)	Erythrocyte  protoporphyrin   levels  (EP, FEP, or ZPP)
C)	CBC and blood  smear
D)	Blood  lead level
E)	Environmental  history
38)	A 15-year-old is participating in high school football practice in August in Texas. He had complained of headache and nausea earlier in practice, but kept playing after a cup of water. He is now confused and combative. He is dizzy and sweating profusely. His temperature is 41°C (105.8°F).  Therapy should  consist of which of the   following?
A)	Provide  oral rehydration solutions
B)	Administer   acetaminophen rectally
C)	Order to rest on the  bench until  symptoms resolve
D)	Initiate  whole  body  cold  water immersion
E)	Tell him  to go take a shower and rest until  the next day’s  practice
39)	As part of your anticipatory guidance to new parents of a healthy new- born, you suggest putting  the child  in  which of the following   positions  for  sleep?
A)	Supine  position
B)	Prone position
C)	Seated position
D)	Trendelenburg  position
E)	A hammock
40)	A mentally retarded 14-year-old boy has a long face, large ears, micropenis, and large testes. Chromosome  analysis  is  likely   to demonstrate  which of the following?
A)	Trisomy 21
B)	Trisomy 18
C)	Trisomy 13
D)	Fragile  X syndrome
E)	Williams   syndrome
41)	A 5-month-old  child  with  poor  growth presents to the ER with generalized  tonic-clonic seizure activity of about 30-minute duration that stops upon the administration of lorazepam. Which  of the following  historical  bits  of information  gathered from the  mother is  most likely to lead to the correct diagnosis  in  this  patient?
A)	The child  has had congestion  without  fever for the past 3 days
B)	The child  is  developmentally  normal,  as are his  siblings
C)	The mother  has been diluting   the infant’s  formula  to make it  last longer  
D)	The mother  reports there are two dogs  and one cat at home.
E)	The mother  previously  worked as an attorney in  an energy-trading firm

42) The term infant pictured below weighs 2200 g (4 lb, 14 oz). He is found to have a ventricular septal defect on cardiac evaluation. This infant appears to have features consistent with which of the following?
A)	Perinatal phenytoin  exposure
B)	Trisomy 21
C)	Alport  syndrome
D)	Fetal alcohol  syndrome
E)	Infant of diabetic  mother
43)	A newborn is  noted to be quite  jaundiced  at 3 days of life.  Laboratory data demonstrate his total bilirubin  to be 17.8 mg/dL  (direct bilirubin   is  0.3 mg/dL).  Which of the following   factors  is  associated with  an increased risk of neurologic   damage in  a jaundiced newborn?
A)	Metabolic  alkalosis
B)	Increased attachment of bilirubin to binding sites caused by drugs such as sulfisoxazole
C)	Hyperalbuminemia
D)	Neonatal sepsis
E)	Maternal ingestion  of phenobarbital  during  pregnancy
44)	A 2-hour-old full-term newborn infant is noted by the nursing staff to be having episodes of cyanosis and apnea. Per nursery protocol they place an oxygen saturation monitor on him. When they attempted to feed him, his oxygen levels drop into the 60s. When he is  stimulated and cries, his  oxygen levels increase into  the 90s. Which of the following   is the most   important  next step to quickly   establish  the diagnosis?
A)	Echocardiogram
B)	Ventilation   perfusion scan
C)	Passage of catheter into nose
D)	Hemoglobin   electrophoresis
E)	Bronchoscopic  evaluation  of palate  and larynx
45)	A mother calls  you  frantic because she has just been diagnosed  with chicken pox. She delivered 7 days ago a term infant that appears to be eating, stooling, and urinating well. The child has been afebrile and seems to be doing well. Which of the following is the most appropriate  step in  management?
A)	Isolate  the infant  from the mother.
B)	Hospitalize  the  infant  in  the  isolation ward.
C)	Administer  acyclovir  to the infant.
D)	Administer  varicella-zoster  immunoglobulin   to the  infant.
E)	Advise  the  mother to continue  regular  well-baby  care for the infant.
 46)	A mother wishes to breast-feed her newborn infant, but is  worried about medical  conditions  that would prohibit her from doing  so. You counsel her that of her listed  conditions, which of the following  is  a contraindication  to  breast-feeding?
A)	Upper respiratory  tract infection
B)	Cracked and bleeding  nipples
C)	Mastitis
D)	Inverted nipples
E)	HIV infection
47)	A mother delivers  a neonate with  meconium  staining  and Apgar scores of 3 at 1 and 5  minutes of life. She had no prenatal care and the delivery was by emergency cesarean section for what the  obstetricians  report as “severe fetal bradycardia.” Which  of the  following sequelae could  be expected to develop  in  this  intubated  neonate with  respiratory distress?
A)	Sustained  rise  in  pulmonary  arterial pressure
B)	Hyperactive bowel sounds
C)	Microcephaly  with micrognathia
D)	Cataracts
E)	Thrombocytosis
48)	A 2-year-old boy is being followed  for congenital  cytomegalovirus  (CMV) infection.  He is deaf and developmentally delayed. The child’s mother informs you that she has just become pregnant and is concerned that the new baby will be infected and may develop serious consequences. Which of the following   is  true?
A)	The mother  has antibodies  to CMV that are passed to the  fetus.
B)	The mother’s  infection  cannot become reactivated.
C)	The likelihood   that the  new baby will  become clinically   ill  is  approximately  80%.
D)	Termination  of pregnancy is  advised.
E)	The new infant should  be isolated  from the older   child.
49)	A full-term infant is born after a normal pregnancy; delivery, however, is complicated  by marginal placental separation. At 12 hours of age, the child, although appearing to be in good health, passes a bloody meconium stool. For  determining  the  cause of the bleeding,  which  of the following  diagnostic  procedures should  be performed  first?
A)	A barium enema
B)	An Apt test
C)	Gastric lavage with  normal  saline
D)	An upper  gastrointestinal series
E)	A platelet  count,  prothrombin   time,  and partial  thromboplastin time
50)	As you are about to step out of a newly delivered  mother’s room,  she mentions  that she wants to breast-feed her healthy infant, but that her obstetrician was concerned about one of the medicines she was taking. Which of the woman’s medicines, listed below, is clearly contraindicated  in breast-feeding?
A)	Ibuprofen  as needed for pain  or fever
B)	Labetalol for  her chronic  hypertension
C)	Amphetamines  for her attention  deficit  disorder
D)	Carbamazepine  for  her seizure disorder
E)	Acyclovir  for her HSV outbreak
51)	A recovering premature infant who weighs 950 g (2 lb, 1 oz) is fed breast milk to provide 120 cal/kg/d.  Over the ensuing  weeks, the baby is  most apt to develop  which of the  following?
A)	Hypernatremia
B)	Hypocalcemia
C)	Blood  in  the stool
D)	Hyperphosphatemia
E)	Vitamin  D toxicity
52)	A primiparous woman whose blood type is O positive gives birth at term to an infant who has A-positive  blood  and a hematocrit of 55%. A total serum bilirubin   level obtained  at 36 hours   of age is 12 mg/dL. Which of the following  additional  laboratory findings  would  be  characteristic of ABO hemolytic  disease in  this  infant?
A)	A normal  reticulocyte count
B)	A positive   direct Coombs test
C)	Crescent-shaped red blood  cells  in  the blood smear
D)	Elevated  hemoglobin
E)	Petechiae

53) The nurse from the level 2 neonatal intensive care nursery calls you to evaluate a baby. The infant, born at 32 weeks’ gestation, is now 1 week old and had been doing well on increasing nasogastric feedings. This afternoon, how- ever, the nurse noted that the infant has vomited the last two feedings and seems less active. Your examination reveals a tense and distended abdomen with decreased bowelsounds. As you are evaluating the child, he has a grossly bloody stool. The plain film of his abdomen is shown. The next step in your management of this infant should include which of the following?
A)	Surgical  consultation  for  an emergent exploratory laparotomy.
B)	Continued  feeding of the  infant,  as gastroenteritis  is  usually  self-limited.
C)	Stool culture to identify the etiology of the bloody diarrhea and an infectious diseases consultation.
D)	Stopping feeds, beginning intravenous fluids, ordering serial abdominal films, and initiating    systemic antibiotics.
E)	Removal of nasogastric tube, placement of a transpyloric tube and, after confir- mation via radiograph of tube positioning, switching feeds from nasogastric to nasoduodenal.

54) An infant weighing 1400 g (3 lb) is born at 32 weeks’ gestation. Initial evaluation was benign, and the infant was transferred to the level 2 nursery for prematurity. The nurse there calls at 1 hour of life and reports the infant is tachypneic. Vital signs include a heart rate of 140 beats per minute, a respiratory rate of 80 breaths per minute, a temperature of 35°C (95°F), and a peripheral oxygen saturation of 98%. The lungs are clear with bilateral breath sounds and there is no murmur; the infant is in no dis- tress. The child’s chest radiograph is shown. Which of the following is the most appropriate next step in evaluating the infant?
A)	Obtain  a complete  blood  count  and differential.
B)	Perform a lumbar  puncture.
C)	Administer  intravenously  5cc of  D50W.
D)	Place the infant  under a warmer.
E)	Administer   supplemental oxygen.
55)	Two new mothers are discussing their infants outside the neonatal intensive care unit. Both were born at 36 weeks’ gestation. One infant weighs 2600 g (5 lb, 12 oz)  while  the other infant weighs 1600 g (3 lb,  8 oz). The mother  of the second infant  should  be told  that her child  is  more  likely   to have which of the following   conditions?
A)	Congenital  malformations
B)	Low hematocrit
C)	Hyperglycemia
D)	Surfactant deficiency
E)	Rapid  catch-up growth
56)	A 3-day-old infant, born at 32 weeks’ gestation and weighing 1700 g (3 lb, 12 oz), has three episodes of apnea, each lasting 20 to 25 seconds and occurring after a feeding. During these episodes, the heart rate drops from 140 to 100 beats per minute, and the child remains motionless; between episodes, however, the child displays normal activity. Blood sugar is 50 mg/dL and serum calcium is normal. Which of the following is most likely true regarding the child’s   apneic periods?
A)	They are due to an immature  respiratory  center.
B)	They are a part of periodic   breathing.
C)	They are secondary to hypoglycemia.
D)	They are manifestations  of seizures.
E)	They are evidence of underlying   pulmonary   disease.
57)	You have an 11-day-old term infant in your office for a well-child visit.  The mother notes that  she received a letter that day from the state’s Department of Health reporting that her child’s newborn screen had come back abnormal, indicating possible galactosemia. Which of the following   is  the  most appropriate  management at this point?
A)	Discontinue   oral feeds and begin  total parenteralnutrition.
B)	Supplement  her breast-feeding with  a multivitamin.
C)	Refer to endocrinology   for evaluation.
D)	Discontinue  breast-feeding and initiate   soy formula  feedings
E)	Ultrasound  of pancreas.
58)	The father of a 1-week-old infant  comes to the office in  a panic. He has just  noticed on his  child  a right  anterior shoulder  mass that seems ten- der. The father is  an osteosarcoma survivor  and fears the child  has the same malignancy.  In reviewing  the baby’s discharge papers, you note the child was a term, appropriate-for-gestational-age vaginal delivery with a birth weight  of 3200  g (7 lb,  1 oz). Apgar scores were 9 at 1 and 5 minutes.  Your examination is significant for a large firm mass on the right clavicle; the rest of the examination is normal. Management of this  problem  should  include  which  of the following?
A)	Magnetic  resonance imaging  of the  right shoulder
B)	Reassurance and supportive  care
C)	A biopsy  of the mass for culture  and cytology
D)	Referralto an orthopedic   surgeon
E)	Skin  biopsy  to test for osteogenesis  imperfecta
59)	A 1-day-old infant who was born by a difficult forceps delivery is  alert and active. She does not move her left arm spontaneously  or during  a Moro  reflex. Rather, she prefers to maintain it internally rotated by her side with the forearm extended and pronated. The rest of her physical examination is normal. This clinical scenario most likely indicates which  of the following?
A)	Fracture of the  left clavicle
B)	Fracture of the  left humerus
C)	Left-sided  Erb-Duchenne paralysis
D)	Left-sided Klumpke  paralysis
E)	Spinal  injury   with  left hemiparesis
60)	You are examining a newborn infant in the well-baby nursery. The infant was the product of a benign pregnancy and vaginal delivery; he appears to be in no distress. Interestingly, your measurement of fronto- occipital head circumference is about 2 cm larger than the initial measurement done severalhours before. Your examination otherwise is significant  for tachycardia and a “squishy” feel to the entire scalp. You can elicit a fluid wave over the scalp. Management of this  condition  should  include  which of the   following?
A)	Transfer to the  newborn ICU
B)	Observation  and parental reassurance
C)	CT scan of the skull  with  bone windows
D)	Surgical  drainage
E)	Elevation  of the head of the  crib
61)	A 19-year-old primiparous woman develops toxemia  in  her last trimester of pregnancy and during the course of her labor is treated with magnesium sulfate. At 38 weeks’ gestation, she delivers a 2100-g (4-lb, 10-oz) infant with Apgar scores of 1 at 1 minute and 5 at 5 minutes. Laboratory studies at 18 hours of age reveal a hematocrit of 79%, platelet  count  of   100,000/μL,  glucose  41  mg/dL,  magnesium  2.5 mEq/L, and calcium  8.7 mg/dL.  Soon  after, the infant has a generalized convulsion. Which of the following is the most likely cause of the infant’s  seizure?
A)	Polycythemia
B)	Hypoglycemia
C)	Hypocalcemia
D)	Hypermagnesemia
E)	Thrombocytopenia
62)	An infant who appears to be of normal size is noted to be lethargic and somewhat limp after birth. The mother is 28 years old, and this is her fourth delivery. The pregnancy was uncomplicated, with normal fetalmonitoring prior to delivery. Labor was rapid, with local anesthesia and intravenous meperidine (Demerol) administered for maternal pain control. Which  of the following   therapeutic maneuvers is  likely   to improve  this  infant’s  condition most rapidly?
A)	Intravenous infusion   of 10% dextrose in   water
B)	Administration   of naloxone   (Narcan)
C)	Administration   of vitamin  K
D)	Measurement of electrolytes  and magnesium  levels
E)	Neurologic   consultation
63)	At 43 weeks’ gestation, a long, thin infant is delivered. The infant is apneic, limp, pale, and covered with ―pea soup‖ amniotic fluid. Which of the following is the best first step in the resuscitation  of this  infant at delivery?
A)	Intubation  and suction  of the trachea; provision   of oxygen
B)	Artificial  ventilation   with bag and mask
C)	Chest compressions
D)	Administration   of 100%  oxygen  by mask
E)	Catheterization  of the  umbilical  vein

64) The newborn pictured below was born at home and has puffy, tense eye- lids; red conjunctivae; a copious amount of purulent ocular discharge; and chemosis 2 days after birth. Which of the following is the most likely diagnosis?
A)	Dacryocystitis
B)	Chemical  conjunctivitis
C)	Pneumococcalophthalmia
D)	Gonococcal  ophthalmia
E)	Chlamydial   conjunctivitis
65)	After an uneventful  labor  and delivery,  an infant  is  born at 32  weeks’ gestation weighing  1500 g (3 lb, 5 oz). Respiratory difficulty develops immediately after birth and increases in intensity thereafter. At 6 hours of age, the child’s respiratory rate is 60 breaths per minute. Examination  reveals grunting,  intercostal retraction, nasal flaring,  and marked cyanosis in  room air. Auscultation reveals poor air movement. Physiologic abnormalities compatible  with these data include  which of the  following?
A)	Decreased lung compliance,  reduced lung  volume,  left-to-right  shunt of  blood
B)	Decreased lung compliance,  reduced lung  volume,   right-to-left  shunt of blood
C)	Decreased lung compliance,  increased lung  volume,  left-to-right  shunt of  blood
D)	Normal lung  compliance,  reduced lung  volume,  left-to-right   shunt of blood
E)	Normal lung  compliance,  increased lung  volume,  right-to-left   shunt of blood
66)	A term infant is born to a known HIV-positive mother. She has been taking antiretroviral medications for the weeks prior to the delivery of her infant. Routine management of the healthy  infant  should  include  which  of the following?
A)	Admission  to the  neonatal intensive  care unit  for close  cardiovascular monitoring
B)	HIV ELISA on the infant  to determine if  congenital  infection  has  occurred
C)	A course of zidovudine   for the  infant
D)	Chest radiographs  to evaluate  for congenital  Pneumocystis carinii
E)	Administration   of IVIG to the  baby to decrease the risk of perinatal HIV  infection
67)	Initial examination of a full-term infant weighing less than 2500 g (5 lb, 8 oz)  shows edema over the dorsum of her hands and feet. Which of the following findings would support a diagnosis   of  Turner syndrome?
A)	A liver  palpable  to 2 cm below the costal  margin
B)	Tremulous  movements  and ankle  clonus
C)	Redundant skin  folds  at the nape of the  neck
D)	A transient, longitudinal   division   of the body  into  a red half  and a pale half
E)	Softness of the parietal bones at the  vertex
68)	You have been recently named as the medical director of the normal newborn nursery in your community hospital and have been asked to write standardized admission orders for all pediatricians  to follow.  Which  of the following  vaccines will  you  include  on these  orders?
A)	Hepatitis  A vaccine
B)	Hepatitis  B vaccine
C)	Combination   diphtheria,  tetanus, and acellular  pertussis vaccine
D)	Inactivated polio  virus
E)	Haemophilus   influenza   B vaccine

69) A 1-week-old black infant presents to you for the first time with a large, fairly well-defined, purple lesion over the buttocks bilaterally, as shown in the photograph. The lesion is not palpable, and it is not warm nor tender. The mother denies trauma and reports that the lesion has been present since birth. This otherwise well-appearing infant is growing and developing normally and appears normal upon physical examination. Which of the following is the most appropriate course of action in this infant?
A)	Report the family  to child  protective  services
B)	Reassurance of the normalcy  of the  condition
C)	Soft tissues films   of the buttocks  to identify   calcifications
D)	Administration   of vitamin  K
E)	Measurement of bleeding  time  as well as factor VII and XI  levels

70) A newborn infant develops respiratory distress immediately after birth. His abdomen is scaphoid. No breath sounds are heard on the left side of his chest, but they are audible on the right. Immediate intubation is successfulwith little or no improvement in clinical status. Emergency chest x-ray is shown (A) along with an x-ray 2 hours later (B). Which of the following is the most likely explanation for this infant’s condition?
A)	Pneumonia
B)	Cystic  adenomatoid  malformation
C)	Diaphragmatic  hernia
D)	Choanal atresia
E)	Pneumothorax

71) Shortly after birth, an infant develops abdominal distention and begins to drool. When she is given her first feeding, it runs out the side of her mouth, and she coughs and chokes. Physical examination reveals tachypnea, inter- costal retractions, and bilateral pulmonary rales. The esophageal anomaly that most commonly causes these signs and symptoms is illustrated by which of the following?
A)	Figure  A
B)	Figure  B
C)	Figure  C
D)	Figure  D
E)	Figure  E
72)	You are advised by the obstetrician that the mother of a baby she has delivered is a carrier of hepatitis B surface antigen (HBsAg-positive). Which of the following is the most appropriate action  in  managing  this infant?
A)	Screen the infant  for HBsAg.
B)	Isolate  the infant  with  enteric precautions.
C)	Screen the mother  for hepatitis  B “e”antigen  (HBeAg).
D)	Administer  hepatitis  B immune  globulin   and hepatitis  B vaccine to the  infant.
E)	Do nothing because transplacentally acquired antibody will prevent infection in the infant.
73)	You are called to a delivery of a term infant, about to be born via cesarean section to a mother with  multiple  medical problems,  including  a 1-month  history  of a seizure  disorder, for which she takes phenytoin; rheumatic heart disease, for which she must take penicillin daily for life; hypertension, for which she takes propranolol; acid reflux, for which she takes aluminum hydroxide; and a deep venous thrombosis in her left calf diagnosed 2 days ago, for which she  was started on a heparin infusion.  The obstetrician  is  concerned about the  possible  effects of the  mother’s multiple  medications  on the  newborn infant.  Which  of the following   medications is  most  likely  to cause harm in  this  newborn infant  at delivery?
A)	Propranolol
B)	Penicillin
C)	Aluminum   hydroxide
D)	Phenytoin
E)	Heparin
74)	Your older sister, her husband, their 2-day-old infant, and their  pet Chihuahua  arrive at your door. The parents of the child are concerned because the pediatrician noted the child was “yellow” and ordered some studies. They produce a wad of papers for you to review. Both the mother and baby have  O-positive  blood.  The  baby’s direct serum bilirubin   is  0.2 mg/dL,  with  a total serum bilirubin of 11.8 mg/dL. Urine bilirubin is positive. The infant’s white blood  cell  count  is  13,000/μL  with a  differential  of  50%  polymorphonuclear   cells,  45%  lymphocytes, and 5% monocytes. The hemoglobin is  17 g/dL, and the platelet count  is 278,000/μL.  Reticulocyte count is 1.5%. The peripheral smear does not show fragments or abnormal cell shapes. Which of the following  is  the most likely   explanation  for this  infant’s skin    color?
A)	Rh or ABO hemolytic  disease
B)	Physiologic   jaundice
C)	Sepsis
D)	Congenital  spherocytic  anemia
E)	Biliary  atresia

75) At the time of delivery, a woman is noted to have a large volume of amniotic fluid. At 6 hours of age, her baby begins regurgitating small amounts of mucus and bile-stained fluid. Physical examination of the infant is normal, and an abdominal x-ray is obtained (see below). Which of the following is the most likely diagnosis of this infant’s disorder?
A)	Gastric  duplication
B)	Pyloric  stenosis
C)	Esophageal atresia
D)	Duodenal atresia
E)	Midgut  volvulus
76)	The mother and father of a newborn come in  for the 2-week checkup. The mother complains of “colic” and asks if she can switch to goat’s milk instead of breast milk. Which of the following  should  be your  main  concern about using  goat’s milk instead of breast milk  or cow’s milk?
A)	It has insufficient  calories.
B)	It has insufficient  folate.
C)	It has insufficient  whey.
D)	It has insufficient  casein.
E)	It has insufficient  fat.

77) You see the newborn baby shown below for the first time in the nursery. You consult plastic and reconstructive surgeon as well as the hospital’s speech therapist. Understandably, the parents have many questions. Which of the following statements is appropriate anticipatory guidance for this family?
A)	Parenteralalimentation  is  recommended to prevent aspiration.
B)	Surgical  closure of the palatal defect should  be done  before 3 months  of age.
C)	Good  anatomic  closure will  preclude the development  of speech  defects.
D)	Recurrent otitis   media  and hearing  loss  are likely complications.
E)	The chance that a sibling  also would  be affected is 1 in   1000.
78)	The mother  of a 2-week-old infant  reports that since birth,  her infant sleeps most of the day;   she has to awaken her every 4 hours to feed, and she will take only an ounce of formula  at a time. She also is concerned that the infant has persistently hard, pellet-like stools. On your examination you find an infant with normal weight and length, but with an enlarged head. The heart rate is  75 beats per minute  and the temperature is  35°C (95°F). The child  is  still jaundiced. You note large anterior and posterior fontanelles, a distended  abdomen, and an umbilical   hernia. This  clinical  presentation is  likely  a result of which of the   following?
A)	Congenital  hypothyroidism
B)	Congenital  megacolon  (Hirschsprung disease)
C)	Sepsis
D)	Infantile  botulism
E)	Normal development
79)	A routine prenatal ultrasound reveals a male fetus with meningomyelocele. The 24-year-old primigravid mother is told the infant will require surgery shortly after birth. You counsel her about the etiology of this defect and the risk of further pregnancies being  similarly  affected,  and state which of the  following?
A)	The hereditary  pattern for this  condition   is  autosomal recessive.
B)	The prenatal diagnosis can be made by the detection of very low levels of alpha- fetoprotein  in  the  amniotic fluid.
C)	Subsequent pregnancies  are not at increased risk  compared to the general population.
D)	Supplementation of maternal diet with folate leads to a decrease in incidence of this condition.
E)	Neither environmental  nor  social factors have been shown to influence  the  incidence.

80) A term, 4200-g (9-lb, 4-oz) female infant is delivered via cesarean section because of cephalopelvic disproportion. The amniotic fluid was clear, and the infant cried almost immediately after birth. Within the first 15 minutes of life, however, the infant’s respiratory rate increased to 80 breaths per minute, and she began to have intermittent grunting respirations. The infant was transferred to the level 2 nursery and was noted to have an oxygen saturation of 94%. The chest radiograph is shown. Which of the following is the most likely diagnosis?
A)	Diaphragmatic  hernia
B)	Meconium  aspiration
C)	Pneumonia
D)	Idiopathic   respiratory distress  syndrome
E)	Transient  tachypnea of  the newborn

81) The infant in the following picture presents with hepatosplenomegaly, anemia, persistent rhinitis, and a maculopapular rash. Which of the following is the most likely diagnosis for this child?
A)	Toxoplasmosis
B)	Glycogen  storage disease
C)	Congenital  hypothyroidism
D)	Congenital  syphilis
E)	Cytomegalovirus  disease

82) A well-appearing, 3200-g (7-lb, 1-oz) black infant is noted to have fifth finger (postaxial) polydactyly. The extra digit has no skeletal duplications and is attached to the rest of the hand by a threadlike soft tissue pedicle (see photograph). Appropriate treatment for this condition includes which of the following?
A)	Chromosomal  analysis
B)	Excision  of extra digit
C)	Skeletal survey for other skeletal  abnormalities
D)	Echocardiogram
E)	Renal ultrasound
83)	An infant born at 35 weeks’ gestation to a mother with no prenatal care is noted to be jittery and irritable, and is having difficulty feeding. You note coarse tremors on examination. The nurses report a high-pitched cry and note severalepisodes of diarrhea and emesis. You  suspect which of  the following?
A)	Fetal alcohol  syndrome
B)	Prenatalexposure  to marijuana
C)	Heroin  withdrawal syndrome
D)	Cocaine  exposure in utero
E)	Tobacco use by  the mother
84)	A previously healthy full-term infant has several episodes of duskiness and apnea during the second day of life.  Diagnostic  considerations  should  include  which  of the  following?
A)	Hemolytic  anemia
B)	Congenital  heart disease
C)	Idiopathic  apnea
D)	Harlequin  syndrome
E)	Hyperglycemia
85)	The signs and symptoms of meningitis in  an infant  can be different than those in  an adult. Which of the following signs and symptoms of meningitis is  more helpful  in  an adult  patient than in  a 4-month-old?
A)	Lethargy
B)	Jaundice
C)	Vomiting
D)	Brudzinski  sign
E)	Hypothermia
86)	A woman gives birth to twins at 38 weeks’ gestation. The first twin weighs 2800  g (6 lb,  3 oz) and has a hematocrit  of 70%; the second twin  weighs 2100  g (4 lb,  10 oz)  and has a hematocrit of 40%. Which of the  following   statements is   correct?
A)	The second twin is at risk for developing respiratory distress, cyanosis, and congestive  heart failure.
B)	The first  twin  is  more likely   to have hyperbilirubinemia   and convulsions.
C)	The second twin  is  at risk  for renal vein thrombosis.
D)	The second twin  probably  has hydramnios  of the amniotic   sac.
E)	The second twin  is  likely   to be pale, tachycardic, and hypotensive.
87)	Parents bring a 5-day-old infant to your office. The mother is O negative and was Coombs positive at delivery. The term child weighed 3055 g (6 lb, 1 oz) at birth and had measured baseline hemoglobin of 16 g/dL and a total serum bilirubin of 3 mg/dL. He passed a black  tarlike stool within  the first 24 hours of life.  He was discharged at 30 hours of  life  with  a  stable axillary  temperature of 36.5°C (97.7°F). Today the infant’s weight  is  3000  g, his  axillary temperature is 35°C (95°F), and he is jaundiced to the chest. Parents report frequent yellow, seedy stool. You redraw labs and find his hemoglobin is now 14 g/dL, and his total serum bilirubin is 13 mg/dL. The change in which of the following parameters is of most concern?
A)	Hemoglobin
B)	Temperature
C)	Body weight
D)	Bilirubin
E)	Stool
88)	You are called to a delivery  of a woman with  no prenatal care; she is in  active labor  but has  no history of amniotic rupture. The biophysical profile done in the emergency center revealed severe oligohydramnios.   When you get this  infant  to the nursery,  you should  carefully  evaluate  him  for which of the following?
A)	Anencephaly
B)	Trisomy 18
C)	Renal agenesis
D)	Duodenal atresia
E)	Tracheoesophagealfistula
89)	A newborn infant becomes markedly jaundiced on the second day of life, and a faint petechial eruption, first noted at birth, is now a generalized purpuric  rash. Hematologic  studies for hemolytic   diseases are negative.  Acute management should  include   which of the following?
A)	Liver ultrasound
B)	Isolation  of the  infant from pregnant hospital   personnel
C)	Urine drug  screen on the infant
D)	Discharge with  an early follow-up  visit  in  2 days to recheck bilirubin
E)	Thyroid  hormone  assay
90)	A 14-year-old girl, angry at her mother for taking away her MP3 player, takes an unknown quantity of a friend’s pills. Within the first hour she is sleepy, but in the emergency center she develops a widened QRS complex on her electrocardiogram (ECG), hypotension, and right  bundle  branch block.  The therapy you  would  initiate   for this ingestion  is which of the following?
A)	N-acetylcysteine  (Mucomyst)
B)	Naloxone
C)	Intensive care unit (ICU) admission, close monitoring, and possible Fab anti- body fragments
D)	Ethanol
E)	Deferoxamine
91)	A 10-year-old boy, the star pitcher for the Salt Lake City Little League baseball team, had a sore throat about 2 weeks ago but did not tell anyone because he was afraid he would miss the play-offs. Since severalchildren have been diagnosed with rheumatic fever in the area, his mother is worried that he may be at risk as well. You tell her that several criteria must be met to make the diagnosis but the most common finding is which of the following?
A)	Carditis
B)	Arthralgia
C)	Erythema  marginatum
D)	Chorea
E)	Subcutaneous  nodules

92) You are seeing a 2-year-old boy for the first time. His father denies any past medical or surgical history, but does note that the child’s day care recently sent a note home asking about severalepisodes, usually after the child does not get what he wants, when he “breathes funny” and sits in a corner with his knees under his chin for a few minutes. The day-care staffers think this “self-imposed time-out” is a good thing, but they worry about the breathing. One teacher even though he once looked blue, but decided that it was probably because of the finger paints he had been using. On examination, you identify a right ventricular impulse, a systolic thrill along the left sternal border, and a harsh systolic murmur (loudest at the left sternal border but radiating through the lung fields). His chest radio- graph and ECG are shown. Which of the following congenital cardiac lesions would you expect to find in this child?
A)	Patent ductus arteriosus
B)	Right  ventricular   outflow obstruction
C)	Atrial  septal defect (ASD)
D)	Transposition  of the great vessels with  a patent foramen ovale
E)	Hypoplastic   left heart
93)	The parents of a 2-month-old baby boy are concerned about his risk of coronary artery disease because of the recent death of his 40-year-old maternal uncle from a myocardial  infarction. Which  of the following   is  the  most appropriate  management in  this situation?
A)	Screen the parents for total cholesterol.
B)	Counsel the parents regarding appropriate dietary practices for a 2-month-old infant and test him  for total cholesterol at 6 months  of age.
C)	Reduce the infant’s dietary fat to less than 30% of his calories by giving him skim milk.
D)	Initiate  lipid-lowering   agents.
E)	Recommend yearly ECGs  for the  patient.

94) For the past year, a 12-year-old boy has had recurrent episodes of swelling of his hands and feet, which has been getting worse recently. These episodes occur following exercise and emotional stress, last for 2 to 3 days, and resolve spontaneously. The last episode was accompanied by abdominal pain, vomiting, and diarrhea. The results of routine laboratory workup are normal. An older sister and a maternal uncle have had similar episodes, but they were not given a diagnosis. He presents today with another episode as shown in the photographs on the next page. Which of the following is the most likely diagnosis?
A)	Systemic  lupus  erythematosus
B)	Focal glomerulosclerosis
C)	Congenital  nephrotic  syndrome
D)	Hereditary angioedema
E)	Henoch-Schönlein   purpura
95)	A newborn is diagnosed with congenital heart disease. You counsel the family that the incidence  of heart disease in  future  children  is  which of the following?
A. 1%
B.  2% to 6% 
C.    8% to 10%
D.    15% to 20%
E.    25% to 30%
96)	During a regular checkup of an 8-year-old child, you note a loud  first heart sound  with a fixed and widely split second heart sound at the upper left sternalborder that does not change with respirations. The patient is otherwise active  and healthy.  Which  of the following  heart lesions most likely   explains  these findings?
A)	Atrial septal defect (ASD) 
B)	Ventricular  septal defect (VSD)
C)	Isolated  tricuspid  regurgitation
D)	Tetralogy  of Fallot
E)	Mitral  valve prolapse

97) A 2-year-old boy is brought into the emergency room with a complaint of fever for 6 days and the development of a limp. On examination, he is found to have an erythematous macular exanthem over his body as shown in image A, ocular conjunctivitis, dry and cracked lips, a red throat, and cervical lymphadenopa- thy. There is a grade 2/6 vibratory systolic ejection murmur at the lower left sternal border. A white blood cell (WBC) count and differential show predominant neutrophils with increased platelets on smear. Later, he develops the findings as seen in image B. Which of the following is the most likely diagnosis?
A)	Scarlet fever
B)	Rheumatic  fever
C)	Kawasakidisease
D)	Juvenile   rheumatoid arthritis
E)	Infectious  mononucleosis
98)	An ill-appearing 2-week-old baby girl is brought to the emergency room.  She is  pale and dyspneic with a respiratory rate of 80 breaths per minute. Heart rate is 195 beats per minute, heart sounds are distant, a gallop is heard, and she has cardiomegaly on x-ray. An echocardiogram demonstrates poor ventricular function, dilated  ventricles,  and dilation  of the left atrium.  An ECG shows ventricular  depolarization   complexes  that have low  voltage. Which  of the following   is  the most likely   diagnosis  based on this  clinical  picture? 
A)	Myocarditis
B)	Endocardial  fibroelastosis
C)	Pericarditis
D)	Aberrant left coronary artery arising  from  pulmonary artery
E)	Glycogen  storage disease of the heart
99)	A newborn infant has mild cyanosis, diaphoresis, poor peripheral pulses, hepatomegaly, and cardiomegaly.  Respiratory rate is  60 breaths per minute,  and heart rate is  250  beats per minute.  The  child  most likely   has congestive  heart failure  caused by which  of the following?
A)	Large ASD and valvular  pulmonic   stenosis
B)	VSD and transposition  of the great vessels
C)	Total anomalous  pulmonary  venous  return
D)	Hypoplastic   left  heart syndrome
E)	Paroxysmal atrial tachycardia

100) A 3-month-old infant is brought to your office for pallor and listless- ness. Your physical examination reveals tachycardia that is constant and does not vary with crying. He has no hepatomegaly and the lungs are clear. His ECG is shown. Which of the following is the most appropriate initial management of this patient?
A)	Rapid  verapamil infusion
B)	Transthoracic pacing  of  the heart
C)	Carotid  massage
D)	DC cardioversion
E)	Precordial thump
101)	A 2-year-old child with minimal cyanosis has an S3 and S4 (a quadruple rhythm), a systolic murmur in the pulmonic area, and a middiastolic murmur along the lower left sternal border. An ECG shows right atrial hypertrophy  and a ventricular  block  pattern in  the right chest leads. Which  of the  following  is  the most  likely  diagnosis?
A)	Tricuspid  regurgitation  and pulmonic   stenosis
B)	Pulmonic  stenosis and a VSD (tetralogy  of  Fallot)
C)	Atrioventricular  canal
D)	Ebstein  anomaly
E)	Wolff-Parkinson-White   syndrome

102) A 4-year-old girl is brought to the pediatrician’s office. Her father reports that she suddenly became pale and stopped running while he had been playfully chasing her and her pet Chihuahua. After 30 minutes, she was no longer pale and wanted to resume the game. She has never had a previous episode and has never been cyanotic. Her physical examination was normal, as were her chest x-ray and echocardiogram. An ECG showed the pattern seen on the next page, which indicates which of the following?
A)	Paroxysmal ventricular  tachycardia
B)	Paroxysmal supraventricular  tachycardia
C)	Wolff-Parkinson-White   syndrome
D)	Stokes-Adams pattern
E)	Excessive stress during  play
103)	A child has a 2-week history of spiking fevers, which have been as high  as 40°C (104°F). She has spindle-shaped swelling of finger joints and complains of upper sternal pain. When she has fever, the parents note a faint salmon-colored  rash that resolves with the resolution of the fever. She has had no conjunctivitis or mucositis, but her heart sounds are muffled and she has increased pulsus paradoxus. Which of the following is the most likely diagnosis?
A)	Rheumatic  fever
B)	Juvenile   rheumatoid arthritis
C)	Toxic  synovitis
D)	Septic arthritis
E)	Osteoarthritis
104)	A cyanotic newborn is  suspected of having  congenital  heart disease. He has an increased left ventricular impulse and a holosystolic murmur along the left sternal border. The ECG shows left-axis  deviation  and left  ventricular  hypertrophy  (LVH). Which of  the  following   is  the  most likely  diagnosis?
A)	Transposition  of the  great arteries
B)	Truncus  arteriosus
C)	Tricuspid  atresia
D)	Tetralogy  of Fallot
E)	Persistent fetal circulation
105)	A 3-day-old infant with a single second heart sound has had progressively deepening cyanosis since birth but no respiratory distress. Chest radiography demonstrates no cardiomegaly and normal pulmonary vasculature. An ECG shows an axis of 120°and right ventricular  prominence.  Which  of the following  congenital  cardiac malformations  is  most likely   responsible  for the cyanosis?
A)	Tetralogy  of Fallot
B)	Transposition  of the  great vessels
C)	Tricuspid  atresia
D)	Pulmonary  atresia with  intact ventricular  septum
E)	Total anomalous  pulmonary  venous  return below  the diaphragm
106)	During a physical examination  for participation  in  a sport, a 16-year- old  girl  is  noted to have a late apical systolic murmur, which is preceded by a click. The rest of the cardiac examination is normal. She states that her mother also has some type of heart “murmur” but knows nothing  else about it.  Which  of the following   is  the most likely    diagnosis?
A)	ASD
B)	Aortic stenosis
C)	Tricuspid  regurgitation
D)	Mitral  valve prolapse
E)	VSD
107)	A previously normal newborn infant in a community hospital nursery is noted to be cyanotic at 14 hours of life.  She is  placed on a face mask with oxygen  flowing  at 10 L/min.   She remains cyanotic, and her pulse oxymetry reading does not change. An arterial blood gas shows her PaO2 to be 23 mm Hg. Bilateral breath sounds are present, and she has no murmur. She is breathing deeply and quickly, but she is not retracting. While you are waiting for the transport team from the  nearby children’s  hospital,  you should  initiate  which  of the following?
A)	Indomethacin  infusion
B)	Saline  infusion
C)	Adenosine  infusion
D)	Prostaglandin  E1 infusion
E)	Digoxin   infusion
108)	You are asked to evaluate an infant born vaginally 3 hours  previously  to a mother whose only pregnancy complication was poorly  controlled  gestational diabetes. The  nursing staff noticed  that the  infant  was breathing abnormally.  On examination,  you  find  that the infant  is  cyanotic, has irregular, labored  breathing,  and has decreased breath sounds on  the right side. You also note decreased tone in the right arm. You provide oxygen and order a stat portable chest radiograph, which is normal. Which of the following studies is  most likely  to confirm  your diagnosis?
A)	Nasalwash for viral culture
B)	Fiberoptic   bronchoscopy
C)	Chest CT
D)	Chest ultrasound
E)	Induced sputum  culture
109)	A 10-month-old infant has poor weight gain, a persistent cough, and a history of severalbouts of pneumonitis.  The mother describes the child  as having  very large, foul-  smelling stools for months. Which  of the following  diagnostic  maneuvers is  likely  to result  in  the  correct diagnosis  of this child?
A)	CT of the chest
B)	Serum immunoglobulins
C)	TB skin test
D)	Inspiratory  and expiratory  chest x-ray
E)	Sweat chloride  test

110) A previously well 1-year-old infant has had a runny nose and has been sneezing and coughing for 2 days. Two other members of the family had similar symptoms. Four hours ago, his cough became much worse. On physical examination, he is in moderate respiratory distress with nasal flaring, hyper- expansion of the chest, and easily audible wheezing without rales. His chest radiographs are shown. Which of the following is the appropriate next course of action?
A)	Monitoring   oxygenation  and fluid  status alone
B)	Inhaled  epinephrine  and a single  dose  of steroids
C)	Acute-acting bronchodilators   and a short course of oral steroids
D)	Emergent intubation   and antibiotics
E)	Chest tube placement

111) A 6-year-old girl presents with a 2-day history of cough and fever. At your office she has a temperature of 39.4°C (103°F), a respiratory rate of 45 breaths per minute, and decreased breath sounds on the left side. Her chest x-ray is shown below. Which of the following is the most appropriate initial treatment?
A)	N-acetylcysteine  chest physiotherapy
B)	Vancomycin
C)	Partial lobectomy
D)	Postural drainage
E)	Placement of tuberculosis  skin  test
112)	A 2-year-old girl  is  playing  in  the garage with her Chihuahua,  only  partially supervised by her father, who is weed-whacking around the garden gnomes in  the front yard. He finds  her in  the garage, gagging  and vomiting.   She smells  of gasoline.  In a few minutes she stops vomiting,   but  later that day she develops  cough, tachypnea, and subcostal retractions. She is brought to your emergency center. Which of the following is the most appropriate  first  step in management?
A)	Administer  charcoal
B)	Begin  nasogastric lavage
C)	Administer  ipecac
D)	Perform pulse  oximetry  and arterial blood  gas
E)	Administer   gasoline-binding    agent intravenously

113) A 3-year-old girl is admitted with the x-ray shown below. The child lives with her parents and a 6-week-old brother. Her grandfather stayed with the family for 2 months before his return to the West Indies 1 month ago. The grandfather had a 3-month history of weight loss, fever, and hemoptysis. Appropriate management of this problem includes which of the following?
A)	Bronchoscopy and culture  of washings  for all family   members
B)	Placement of a Mantoux  test on the 6-week-old  sibling
C)	Isolating  the  3-year-old patient  for 1 month
D)	Treating the  3-year-old  patient with  isoniazid   (INH) and rifampin
E)	HIV testing  for all  family members
114)	You are asked to evaluate a 4-year-old boy admitted to your local children’s hospital with a diagnosis of pneumonia. The parents state that the child has had multiple, intermittent episodes of fever and respiratory difficulty  over the past 2 years, including   cyanosis,  wheezing, and dyspnea; each episode lasts for about 3 days. During each event he has a small amount of hemoptysis, is diagnosed with left lower lobe pneumonia,  and improves  upon treatment. Repeat radiographs done several days after each event are reportedly normal. His examination on the current admission  is  significant  for findings  similar  to those described above, as well as digital clubbing. Which of the following is the most appropriate primary recommendation?
A)	Intravenous  cephalosporin  and oral macrolide  therapy
B)	Modified  barium  swallow  study  to evaluate for aspiration
C)	Nasalswab for  viral culture
D)	Incentive  spirometry
E)	Bronchoalveolar  lavage
115)	A previously healthy, active, 18-month-old African American child presents with unilateral nasal obstruction and foul-smelling discharge. The child’s examination is otherwise unremarkable.  Which  of the following   is  the  most likely  diagnosis?
A)	Foreign  body
B)	Nasalpolyps
C)	Frontal sinusitis
D)	Deviated septum
E)	Choanal atresia
116)	A 7-year-old child is  brought  by his  mother for a school physical.  His growth parameters show his height to be 50th percentile and his weight to be significantly higher than  95th percentile. His mother complains that he always seems sleepy during  the day and that he  has started complaining of headaches. His second-grade teacher has commented that he has difficulty  staying  awake in  class. His mother  complains  that he  wakes up the  whole  house with  his  snoring  at night.  Which  of the following   is  the  most appropriate  next step in evaluating  and managing  this  condition?
A)	Try steroids  to decrease tonsillar  and adenoid  hypertrophy.
B)	Refer to an otolaryngologist    for tonsillectomy   and adenoidectomy.
C)	Arrange for continuous  positive  airway pressure (CPAP) at  home.
D)	Arrange for home  oxygen  therapy for use at night.
E)	Arrange for  polysomnography.
117)	You admitted  to the  hospital  the previous  evening  a 1-year-old  boy who presented with cough, fever, and mild hypoxia. At the time of his admission,  he had evidence of a right  upper lobe consolidation on his chest radiograph.  A blood  culture  has become positive  in  less than 24 hours for Staphylococcus aureus. Approximately 20 hours into his hospitalization, the nurse calls you because the child has acutely worsened over the previous few minutes, with markedly increased work in breathing, increasing  oxy- gen requirement,  and hypotension.  As you move swiftly to the child’s  hospital  room, you tell the nurse to order which of the    following?
A)	A second chest radiograph  to evaluate for pneumatocele  formation
B)	A large-bore needle and chest tube kit for aspiration of a probable tension pneumothorax
C)	A change in  antibiotics  to include   gentamicin
D)	A sedative  to treat the child’s  attack of severe anxiety
E)	A thoracentesis kit  to drain  his  probable  pleural effusion
118)	A fully immunized 2-year-old presents to the emergency room with severaldays of low-grade fever, barking  cough, and noisy  breathing. Over the past few hours he has  developed a fever of 40°C (104°F) and looks toxic. He has inspiratory and expiratory stridor.  The family has not noticed drooling, and he seems to be drinking without pain. Direct laryngoscopy reveals a normal epiglottis. The management of this disease process includes which  of the following?
A)	Intubation  and intravenous  antibiotics
B)	Inhaled  epinephrine  and oral steroids
C)	Inhaled  steroids
D)	Observation in  a cool mist  tent
E)	Oral antibiotics   and outpatient  follow-up

119) A 6-year-old, fully immunized boy is brought to the emergency room with a 3-hour history of fever to 39.5°C (103.1°F) and sore throat. The child appears alert, but anxious and toxic. He has mild inspiratory stridor and is drooling. He is sitting on the examination table leaning forward with his neck extended. A lateral radiograph of his neck is shown below. Which of the following is the most appropriate immediate management of this patient?
A)	Examine  the throat and obtain  a culture.
B)	Obtain  an arterial blood  gas and start an IV line.
C)	Administer  a dose of nebulized   epinephrine.
D)	Prepare to establish  an airway in  the operating room.
E)	Admit  the child  and place him  in  a mist tent.
120)	A 4-year-old boy was admitted to the hospital  last night  with the complaint  of  “difficulty breathing.” He has no past history of lung infection,  no  recent travel, and no day- care exposure; he does, however, have an annoying tendency to eat dirt. In the emergency center he was noted to be wheezing and to have hepatomegaly. He is able to talk, relaying his concern about his  6-week-old Chihuahua  being  left alone  at home. Laboratory studies revealed marked eosinophilia   (60%  eosinophils).   Which  of the following   tests is  most likely to produce  a specific diagnosis?
A)	Tuberculin  skin  test
B)	Histoplasmin   test
C)	ELISA for  Toxocara
D)	Silver  stain of gastric  aspirate
E)	Stool  examination  for ova and parasites
121)	A 10-year-old girl has had a “cold” for 14 days. In the 2 days prior to the visit to your office, she has developed a fever of 39°C (102.2°F),  purulent  nasaldischarge,  facial pain,  and a daytime cough. Examination of the nose after topical decongestants shows pus in the middle meatus. Which  of the following   is  the most likely   diagnosis?
A)	Brain abscess
B)	Maxillary   sinusitis
C)	Streptococcal throat infection
D)	Sphenoid  sinusitis
E)	Middle-ear  infection
122)	You are awakened in the night by your 2-year-old son, who has developed noisy breathing on inspiration, marked retractions of the chest wall, flaring of the nostrils, and a barking cough. He has had a mild upper respiratory infection (URI) for 2 days. Which of the following   therapies is  indicated?
A)	Short-acting  bronchodilators   and a 5-day course of steroids
B)	Intubation  and antibiotics
C)	Observation for hypoxia   and dehydration  alone
D)	Inhaled  epinephrine  and a dose of steroids
E)	Rigid  bronchoscopy
123)	An 8-year-old girl presents with well-controlled, moderately persistent asthma. Her therapies consist of occasional use of short-acting β-agonists, daily inhaled steroids, and a leukotriene inhibitor. She presents with white patches on her buccal mucosa. You recommend which  of the following?
A)	HIV testing
B)	Tuberculosis  skin  testing
C)	Measurement of serum immunoglobulins
D)	Discontinuation  of all  her asthma  medications
E)	Rinse  her mouth  after use of her inhaled  medications

124) A 13-year-old develops fever, malaise, sore throat, and a dry, hacking cough over severaldays. He does not appear to be particularly sick, but his chest examination is significant for diffuse rales and rhonchi. The chest radio- graph is shown below. Which of the following is the most likely pathogen?
A)	Staphylococcus aureus
B)	Mycobacterium tuberculosis
C)	Haemophilus influenzae
D)	Streptococcus pneumoniae
E)	Mycoplasma pneumoniae
125)	You have just given a 10-year-old boy an injection  of pollen  extract as prescribed by his allergist. You are about to move  on to the next patient  when the boy  starts to complain about nausea and a funny feeling in his chest. You note that his face is flushed and his voice sounds muffled and strained. Which of the following  is  the first  priority  in  managing  this episode  of anaphylaxis?
A)	Preparation for endotracheal intubation  
B)	Intramuscular  injection   of diphenhydramine
C)	Administration   of oxygen
D)	Subcutaneous  injection   of  1:1000 epinephrine
E)	Administration    of corticosteroids
126)	A previously healthy 18-month-old has been in a separate room from his family. The family notices the sudden onset of coughing, which resolves in  a few minutes.  Subsequently,  the patient appears to be normal except for increased amounts of drooling and refusal to take foods  orally.  Which  of the following   is  the  most likely   explanation  for this  toddler’s condition?
A)	Severe gastroesophagealreflux
B)	Foreign body in  the  airway
C)	Croup
D)	Epiglottitis
E)	Foreign  body  in  the esophagus
127)	You receive a telephone call from the mother of a 4-year-old child with sickle-cell anemia. She tells you that the child is breathing fast, coughing, and has a temperature of 40°C (104°F).  Which  of the following   is  the most conservative, prudent course of  action?
A)	Prescribe aspirin  and ask her to call back if  the fever does not respond.
B)	Make an office appointment   for the  next available  opening
C)	Make an office appointment   for the  next day.
D)	Refer the child to the laboratory for an immediate hematocrit, white blood  cell count, and differential.
E)	Admit  the  child  to the hospital.
128)	You are asked by a colleague  to evaluate a 5-year-old boy as a second opinion.   He  has a history of chronic and recurrent upper respiratory tract infections, severaladmissions to the hospital  for pneumonia,  and three surgeries for PE tubes for chronic  otitis  media. Of note   is a right-sided heart on repeated radiographs. Convinced you know the diagnosis  based on history alone, you confirm your  diagnosis  with  a biopsy  of the nasal mucosa. You expect to find  which  of the following?
A)	Eosinophilic   infiltrate
B)	Bordetella pertussis
C)	Absence of nasal mucous  glands
D)	Random orientation   of cilia
E)	Nasalpolyps
129)	A 13-year-old patient with sickle-cell anemia presents with respiratory distress; she has an infiltrate on chest radiograph. The laboratory workup of the patient reveals the following: hemoglobin  5 g/dL; hematocrit 16%; white  blood  cell count  30,000/μL;  and arterial blood (room air) pH 7.1, PO2 35 mm Hg, and PaCO2 28 mm Hg. These values indicate  which  of the following?
A)	Acidemia,  metabolic   acidosis,  respiratory alkalosis,  and hypoxia
B)	Alkalemia,  respiratory  acidosis,  metabolic   alkalosis,  and hypoxia
C)	Acidosis  with  compensatory  hypoventilation
D)	Long-term metabolic   compensation  for  respiratory alkalosis
E)	Primary  respiratory alkalosis
130) A 24-year-old woman arrives in the emergency center in active labor. She is at term, but received no prenatal care after 16 weeks of gestation when she lost her insurance coverage. The mother has an uncomplicated vaginal delivery. You are paged shortly after birth when the baby is noted to have respiratory distress. The infant has diminished breath sounds on the left, and the PMI is shifted toward the right. A chest radiograph is shown. The NG tube you placed earlier reveals the stomach to be below the diaphragm. Which of the following is the most likely diagnosis at this point?
A)	Congenital  cystic  adenomatoid  malformation
B)	Congenital  diaphragmatic   hernia
C)	Bronchogenic  cysts
D)	Congenital  lobar  emphysema
E)	Congenital  pneumonia

131) A 13-year-old boy has a 3-day history of low-grade fever, symptoms of upper respiratory infection, and a sore throat. A few hours before his presentation to the emergency room, he has an abrupt onset of high fever, difficulty swallowing, and poor handling of his secretions. He indicates that he has a marked worsening in the severity of his sore throat. His pharynx has a fluctuant bulge in the posterior wall. A soft tissue radiograph of his neck is shown. Which of the following is the most appropriate initial therapy for this patient?
A)	Narcotic analgesics
B)	Trial of oral penicillin    V
C)	Surgical  consultation  for incision   and drainage  under general anesthesia
D)	Rapid  streptococcalscreen
E)	Monospot  test
132)	A 6-week-old child arrives with a complaint of “breathing fast” and a cough. On examination you note the child to have no temperature elevation, a respiratory rate of 65  breaths per minute, and her oxygen saturation to be 94%. Physical examination also is significant for rales and rhonchi. The past medical history for the child is positive for an eye discharge at 3 weeks of age, which was treated with a topical antibiotic drug. Which of the following   organisms  is  the  most likely   cause of this  child’s condition?
A)	Neisseria gonorrhoeae
B)	Staphylococcus aureus
C)	Group  B streptococcus
D)	Chlamydia trachomatis
E)	Herpesvirus
133)	One of  your  asthmatic patients  arrives for a checkup.  The mother  reports that the child seems to need albuterol daily, especially when exercising, and she has coughing fits that awaken her from sleep about twice  a week. Her grandmother had recommended a Chihuahua as a “cure” for her asthma, but her mother has seen no difference since the arrival of the pet. Appropriate  treatment measures would include   which  of the following?
A)	Short-acting,  inhaledβ-agonists,   as needed
B)	Daily  leukotriene  modifier  with  short-acting  β-agonist
C)	Inhaled  nedocromil  with  short-actingβ-agonists
D)	Medium-dose,  inhaled  corticosteroids  with  short-acting  β-agonists
E)	High-dose,  inhaled  corticosteroids  with  theophylline    and short-actingβ-agonists

134) A previously healthy 2-year-old black child has developed a chronic cough during the previous 6 weeks. He has been seen in different emergency rooms on two occasions during this period and has been placed on antibiotics for pneumonia. Upon auscultation, you hear normal breath sounds on the left. On the right side, you hear decreased air movement during inspiration but none upon expiration. Inspiratory (A) and expiratory (B) radiographs of the chest are shown below. Which of the following is the most appropriate next step in making the diagnosis in this patient?
A)	Measure the patient’s  sweat chloride.
B)	Consult  pediatric  surgery for bronchoscopy.  
C)	Prescribe broad-spectrum oral antibiotics.
D)	Initiate  a trial  of inhaled  β-agonists.
E)	Prescribe appropriate  doses of  oral prednisone.

135) A 4-year-old boy presents with a history of constipation since the age of 6 months. His stools, produced every 3 to 4 days, are described as large and hard. Physical examination is normal; rectalexamination reveals a large ampulla, poor sphincter tone but present anal wink, and stool in the rectal vault. The plain film of his abdomen is shown. Which of the following is the most appropriate next step in the management of this child?
A)	Lower gastrointestinal  (GI)  barium study
B)	Parental reassurance  and dietary counseling
C)	Serum electrolyte measurement
D)	Upper GI  barium study
E)	Initiation   of  thyroid-replacement hormone
136)	A 10-year-old  boy  has been having  “bellyaches”  for about 2 years. They occur at night  as well as during  the day. Occasionally,  he vomits  after the onset of pain.  Occult blood  has been found in his stool. His father also gets frequent, nonspecific stomachaches. Which of  the  following   is  the most  likely diagnosis?
A)	Peptic ulcer
B)	Appendicitis
C)	Meckel diverticulum
D)	Functional  abdominal  pain 
E)	Pinworm  infestation
137)	An 8-year-old boy  presents to your office for a second opinion.   He has a 2-year history of intermittent vomiting, dysphagia,  and epigastric  pain.  His father reports he occasionally gets food “stuck” in his throat. He has been on a proton pump  inhibitor  for 18 months without symptom relief. His past history is significant only for eczema and a peanut allergy. Endoscopy was performed 6 months ago; no erosive lesions were noted and a biopsy  was not performed. You arrange for a repeat endoscopy with  biopsy.  Microscopy  on the  biopsy sample reveals many eosinophils. Treatment of this  condition  should  include  which of  the following?
A)	Corticosteroids
B)	Prolonged  acid blockade
C)	Treatment for  Candida sp.
D)	Treatmentfor Aspergillus sp.
E)	Observation

138) A 1-week-old previously healthy infant presents to the emergency room with the acute onset of bilious vomiting. The abdominal plain film in the emergency department (A) and the barium enema done after admission (B) are shown. Which of the following is the most likely diagnosis for this patient?
A)	Jejunal atresia
B)	Hypertrophic pyloric  stenosis 
C)     Malrotation  with  volvulus
D)	Acute appendicitis
E)	Intussusception

139) The newborn nursery calls to notify you that a 1-day-old baby boy has developed abdominal distension and bilious emesis. Prenatalhistory was significant for areas of echogenic bowel seen on ultrasound. You order an abdominal radiograph; based on the results you order a contrast enema. Both are shown here. This infant is most likely to have which of the following?
A)	Duodenal atresia
B)    Cystic fibrosis
C)	Gastroenteritis
D)	Malrotation  with volvulus
E)	Hirschsprung disease
140)	A 17-year-old adolescent female is 6 weeks postpartum. She presents to the emergency room with the complaints of increased jaundice, abdominal pain, nausea, vomiting, and fever. Her examination is remarkable for jaundice, pain of the right upper quadrant with guarding, and a clear chest. Chest radiographs appear normal. Which of the following   tests is  most likely   to reveal the cause of this pain?
A)	Serum chemistries
B)	Complete blood count  (CBC) with platelets  and differential 
C)    Ultrasound of the right upper quadrant
D)	Upper GI series
E)	Hepatitis panel
141)	An 8-year-old is accidentally hit in  the abdomen  by a baseball bat. After several minutes  of discomfort,  he seems to be fine. Over the ensuing  24 hours, however, he develops  a fever, abdominal pain radiating  to the back, and persistent vomiting.  On examination,  the child appears quite uncomfortable. The abdomen is tender, with decreased bowelsounds throughout, but especially painful in the midepigastric region with guarding. Which  of the following   tests is  most likely   to confirm  the diagnosis?
A)	Serum amylase levels
B)	CBC with differential  and platelets
C)	Serum total and direct  bilirubin  levels
D)	Abdominal  radiograph
E)	Electrolyte  panel
142)	A 10-month-old baby boy, recently adopted from Guyana, has a 5-hour  history of  crying, with intermittent drawing up of his  knees to his  chest. On the way to the emergency room he passes a loose, bloody stool. He has had no vomiting  and has refused his  bottle  since  the crying began. Physical examination is noteworthy for an irritable infant whose abdomen is very difficult  to examine because of constant crying. His temperature is 38.8C (101.8F). The rectalampulla is empty, but there is some gross blood  on the examining finger. Which of the following  studies  would  be most helpful  in  the immediate  management  of this  patient?
A)	Stool culture
B)	Examination of the stool for ova and parasites  
C)     Air contrast enema
D)	Examination  of the  blood  smear
E)	Coagulation  studies
143)	A 12-month-old girl  has been spitting  up her meals since 1 month  of  age. Her growth is at the 95th percentile, and she is otherwise asymptomatic and without findings on physical examination.  Which  of the following   is  the  most likely  diagnosis?
A)	Pyloric  stenosis
B)	Partial duodenal atresia
C)	Hypothyroidism
D)	Gastroesophageal reflux
E)	Tracheoesophageal fistula
144)	A 14-year-old girl has a 9-month history of diarrhea, abdominal pain (usually periumbilical  and postprandial),  fever, and weight loss.  She has had several episodes of blood  in  her stools.  Which  of the following   is  the most  likely diagnosis?
A)	Chronic  appendicitis
B)	Chronic pancreatitis 
C)     Crohn disease
D)	Bulimia
E)	Gallstones
145)	A 4-year-old boy, recently adopted through  an international  adoption  service, is  noted to have intermittent watery diarrhea, nausea, belching, and abdominal pain. His  weight is  less than the fifth percentile for his age. Which of the following studies would be most helpful in making  the diagnosis?
A)	CBC and differential
B)	ESR
C)	Abdominal  ultrasound
D)	Liver  function studies 
E)	Stool  microscopy  for ova  and parasites
 146)	A 5-month-old child regularly regurgitates a large portion of her feeds. A pH probe  study showed significant periods of low esophageal pH. The child has normal growth and no other significant past medical history. Which of the following is the best management at this point?
A)	Barium  swallow and upper GI  series
B)	Oralreflux  medications
C)	Esophageal  manometry
D)	Close  observation only
E)     Surgical correction with fundoplication
147)	A 2-year-old presents to the emergency center with severaldays of rectal bleeding. The mother first noticed reddish-colored stools 2 days prior to arrival and has since changed severaldiapers with just blood. The child is afebrile, alert, and playful,  and is  eating well without emesis. He is  slightly  tachycardic, and his  abdominal  examination  is  normal.  Which of the following   is  the best diagnostic  study to order to confirm  the   diagnosis?
A)	Exploratory  laparotomy
B)	Barium enema
C)	Ultrasound of the abdomen
D)     Radionucleotide scan
E)	Stool culture
148)	A 15-year-old otherwise healthy boy presents with a complaint of intermittent abdominal distention, crampy abdominal pain,  and excessive flatulence. He first started  noticing these symptoms when he  moved into  his  father’s house, and his  stepmother insisted on milk at dinner every night. He has normal growth, has not lost weight, and has no travel history.  Which  of the following   is  the most appropriate  study to diagnose  his   condition?
A)	Barium  swallow  and upper GI
B)	Hydrogen excretion in  breath after oral administration   of lactose
C)	Esophageal manometry
D)	Stool pH after one to 2 weeks of a lactose-free  diet
E)	Fasting  serum lactose levels
149)	A 6-week-old infant is admitted  to the hospital  with  jaundice.  Her outpatient  blood work demonstrated a total bilirubin of 12 mg/dL with a direct portion of 3.5 mg/dL. Which  of  the following  disorders  is  most likely   to be  responsible?
A)	ABO incompatibility
B)    Choledochal cyst
C)	Rh incompatibility
D)	Gilbert  disease
E)	Crigler-Najjar syndrome
150)	A 2-year-old arrives in the emergency center after having swallowed a button battery from one of her toys. She is breathing comfortably, without  stridor.  Radiographs show the battery to be lodged  in  the esophagus. Which  of the following   is  the correct next step?
A)	Induce emesis with  syrup of  ipecac
B)	Admit for observation, and obtain serial radiographs to document  movement of the battery.
C)	Discharge home with instructions  to monitor  the stool for  the battery.
D)	 Immediate  removal of the battery via  endoscopy.
E)     Encourage oral intake to assist in passage of the battery.
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