Cycle 1 - 2023/2024

For a screening method, which of the following would you prefer to have: **not sure
An accurate method with high sensitivity
A precise method with high sensitivity
An accurate method with high specificity ***
A precise method with high specificity
E. A precise method with low specificity
What is the positive predictive value for: prevalence 0,5%, specificity 80%, sensitivity 60% (to three decimal places)?
TP = 0.199, FP = 0.003, PPV = TP/(TP+FP) = 0.985
TP = 0.8, FP = 0.199, PPV = TP/(TT+FP) = 0.801
TP = 0.003, FP = 0.8, PPV = TP/(PT+FP) = 0.004
TP = 0.003, FP = 0.199, PPV = TP/(TP+FP) = 0.1
TP = 0.6, FP = 0.8, PPV = TP/(T+PFP) = 0.429
Which of the following is false:
Urinalysis is important in screening for many diseases, not just for renal diseases
Urinalysis is restricted to biochemical tests
Urinalysis comprises a set of point of care analyses
Urinalysis is an integral part of examination of every patient
Some urine analyses need to be performed in a central laboratory
Microscopic examination of urine includes all of the following exept:
White blood cells
Red blood cells
Osmolality
Crystals
Bacteria
Biochemical examination of urine includes all of the following except
Casts
Protein
Creatinine
Glucose
Urea
Sodium loss in faeces under normal conditions (no fever or strenuous exercise) is approximately (in mmol/day):
5
10
15
20
25
In an 160 kg man, interstitial fluid is:
12 liters
24 liters
10.5 liters
3.5 liters
5 liters
If sodium concentration is 145 mmol/l and urea and glucose are wnl, serum osmolarity equals
120 mOsm/kg
275 mOsm/kg
240 mOsm/kg
290 mOsm/kg
280 mOsm/kg
In an obese 140kg man, TBW is around
48 L
60 L
50 L
12 L
80 L
ECF sodium in a 120 kg man under normal conditions is around
3700 mmol
2800 mmol
2000 mmol
920 mmol
5000 mmol
One tablespoon of NaCl administrated to a new-born could raise plasma sodium by as much as
70 pmol/l
70 nmol/l
70 mmol/l
70 dmol/l
70 mol/l
Pseudohyperkalemia more often results from:
Decreased amount of protein occupying plasma volume
Hemolysis
Hematological -----
Decreased amount of lipoprotein occupying plasma volume
Rhabdomyolysis
Concentration of potassium in serum is around:
4.5 mmol/l
5.5 mmol/l
6.5 mmol/l
7.5 mmol/l
8.5 mmol/l
The loss of potassium in faeces is estimated to be around (normally, no diarrhea):
0.5 mmol/day
5 mmol/day
15 mmol/day
50 mmol/day
100 mmol/day
In Conn´s or Cushing syndrome the serum sodium concentration rarely rises above: **
70 mmol/L
90 mmol/L
110 mmol/L
130 mmol/L *
150 mmol/L
Recovery of bicarbonate by kidney involves:
Diffusion of CO2 from tubular ell to capillaries
Diffusion of CO2 to tubular lumen
Permanent acidification of urine with exchange with sodium
Transient acidification to urine with exchange with sodium
Regeneration of bicarbonate by kidneys involves:
Diffusion of CO2 from tubular cells to capillaries
Diffusion of CO2 to tubular lumen
Permanent acidification of urine with exchange with sodium
4- Transient acidification of urine with exchange with sodium acidification of urine with exchange with sodium
Which of the following is true
Adding H+, removing bicarbonate or lowering pCO2 will all increase [H+]
Adding H+, adding bicarbonate or lowering pCO2, will all increase [H+]
Adding H+, removing bicarbonate or rising pCO2 will all increase [H+]
Removing H+, adding bicarbonate or lowering pCO2 will all increase [H+]
Removing H+, remocing bicarbonate or lowering pCO2, will all increase [H+]
Which of the following is true:
[H+] = K[H2CO3/(HCO3-]
[H+] = K[HCO3-]/[ H2CO3]
[HCO3-] = [H+]/[ H2CO3]
[H2CO3] = K[HCO3-] /[ H+]
[HCO3-] = K[H2CO3]*[ H+];
Actual HCO3 is measured/estimated by: *
[H+] measured directly from blood equilibrated with standard CO2 pressure of 40 mmHg, then calculate pCO2 and [HCO3-] from pH
PCO2 measured directly from blood equilibrated with standard CO2 pressure of 40mmHg, then calculate [H+] and [HCO3-] from pCO2
[H+] and pCO2 measured directly from blood equilibrated with standard CO2 pressure of 40mmHg, then calculate [HCO3-] from pH and pCO2 **
PCO2 measured directly from blood not left to equilibrate, then calculate [H+] and [HCO3-] from pCO2
[H+] and pCO2 measured directly from blood not left to equilibrate, then calculate [HCO3-] from pH and pCO2
Hypoxia with raised PCO2 indicated:  (type II respiratory failure)
Impaired diffusion
Ventilation/perfusion imbalance
Diminished ventilation
Right to left shunting
Extreme ventilation/perfusion imbalance
Blood gas analysers measure:
[H+] directly, calculate PCO2 and [HCO3-]
PCO2 directly, calculate [H+] and [HCO3-]
[H+] and PCO3 directly, calculate [HCO3-]
[HCO3-] directly, calculate PCO2 and [H+]
[HCO3-] and PCO2 directly, calculate [H+]
Type II respiratory failure is defined as:
Hypoxia and hypocapnia
Hypocapnia
Hypercapnia
Hypoxaemia (hypoxia) and hypercapnia
Hypoxaemia (hypoxia)
25. Above which level can we say a metabolic acidosis is definitely present (choose lowest reasonable answer):
Anion gap greater than 10mmol/l
Anion gap greater than 20mmol/l
Anion gap greater than 30mmol/l
Anion gap greater than 40mmol/l
Anion gap greater than 50mmol/l
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